Clinical trial

Idiopathic Pulmonary Fibrosis and Serum Bank

Name
35RC14_9722
Description
Idiopathic pulmonary fibrosis (IPF) is the most common form of chronic idiopathic diffuse interstitial lung disease (DILD) in adults. It is a fibroproliferative, irreversible disease of unknown cause, usually progressive, occurring mainly from the age of 60 and limited to the lungs. IPF is a serious disease with a median survival rate at diagnosis of 3 years. The aim of the study is to set up a biocollection of serum from patients in a context of idiopathic DILD and a possible or confirmed diagnosis of common interstitial lung disease by chest CT. Patients will be recruited at the consultations of the Rennes Rare Lung Disease Competence Centre. These will be patients in stable condition or in acute exacerbation of IPF.
Trial arms
Trial start
2014-10-22
Estimated PCD
2022-12-28
Trial end
2022-12-28
Status
Completed
Treatment
Blood sample collection
Three additional blood tubes (3 x 8mL) will be collected for this study. They will be added to the traditional diagnostic assessment carried out for their IPF, during their consultation at the competence centre for rare lung diseases. These samples will be taken by a registered nurse in the presence and under the responsibility of the investigator.
Arms:
Patients with DILD
Size
903
Primary endpoint
Determination of circulating CD163 serum concentration
Through study completion, an average of 4 years
Eligibility criteria
Inclusion Criteria: * Patients seen on an outpatient basis and in stable or acute condition * Patient over 18 years of age. * The inclusion criteria will be those edited by the American Thoracic Society (ATS) and the European Respiratory Society (ERS) to diagnosis IPF Exclusion Criteria: * Patients who are unable or unwilling to sign the consent.
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'COHORT', 'timePerspective': 'PROSPECTIVE'}, 'bioSpec': {'retention': 'SAMPLES_WITHOUT_DNA', 'description': 'The aim of the study is to set up a biocollection of serum from patients in a context of idiopathic DILD'}, 'enrollmentInfo': {'count': 903, 'type': 'ACTUAL'}}
Updated at
2023-11-28

1 organization

1 product

3 indications

Indication
Lung Diseases
Indication
Interstitial