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Clinical trial

Effect of Milrinone on the Right Ventricular Strain in Cardiac Surgery

ID
Name
KUH 2023-09-060
Description
The purpose of this study is to analyze the changes in right ventricular strain before and after milrinone administration in order to find out whether milrinone improves RV systolic performance in patients undergoing cardiac surgery.
Trial arms
Trial start
2023-11-03
Estimated PCD
2024-12-01
Trial end
2024-12-01
Status
Recruiting
Treatment
Milrinone
giving intravenous milrinone: 50 mcg/kg loading dose by IV push over 10 minutes, then 0.375-0.75 mcg/kg/ min infusion
Other names:
Milrinone intravenous administration
Size
41
Primary endpoint
1. Right ventricular strain
15 min after milrinone administration
Eligibility criteria
Inclusion Criteria: * patient agree and provide written informed consent. * patient undergoing elective cardiac surgery * preoperative LV EF\>50% (TTE) Exclusion Criteria: * preoperative cardiac dysrhythmia * preoperative IABP * use of other inotropic agents
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'OTHER', 'timePerspective': 'PROSPECTIVE'}, 'enrollmentInfo': {'count': 41, 'type': 'ESTIMATED'}}
Updated at
2024-01-19

1 organization

1 product

2 indications

Organization
Konkuk University Medical Center
Product
Milrinone
Indication
Ischaemic Heart Disease
Indication
Valvular Heart Disease