Association Between Time of Oxytocin Initiation at 2nd Stage of Labor and Adverse Outcomes

0061-22-RMB

Early oxytocin administration at the 2nd stage of labor is associated with a higher rate of vaginal delivery, shorter second stage duration, and fewer adverse maternal and neonatal outcomes.

2023-10-01

2025-10-01

2026-10-01

Recruiting

120

Inclusion Criteria: 1. Singleton pregnancy 2. Maternal age ≥ 18 years' old 3. Oxytocin administration initiated or renewed during second stage of labor Exclusion Criteria: 1. Maternal age \< 18 years' old 2. Multiple gestation pregnancy 3. Known fetal malformations 4. Uterine scar

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'A randomized controlled trial of singleton gestations receiving oxytocin during the second stage of labor at a single tertiary medical center. Women will be randomly allocated to one of two groups - immediate initiation of oxytocin at full dilation versus delayed oxytocin initiation following one hour of full dilation.', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'NONE'}}, 'enrollmentInfo': {'count': 120, 'type': 'ESTIMATED'}}

2023-12-26