Efficacy of Carotenoids on Blood Biomarkers Following A Collision Sport Athletes

STUDY00023019

This is a supplement study being conducted to find out if collision sport athletes who are exposed to repetitive head impacts while supplementing with carotenoids will have decreased pro-inflammatory blood biomarkers, increases in macular pigment optical density, improved contrast sensitivity, greater retinal nerve fiber thickness, and better overall visual quality of life scores compared to collision athletes taking a placebo.

2024-08-01

2024-12-20

2024-12-20

Not yet recruiting

Early phase I

52

Inclusion Criteria: * Collision sport athletes: 1. Penn State student ages 18 and over 2. Any gender 3. Participating in club, or intramural collision-sports and is willing to participate in this study (examples: hockey, lacrosse, soccer, wrestling, rugby, boxing, basketball, cheer). Exclusion Criteria: * For all subjects: 1. Subjects with concurrent injury that would impair their ability to perform the assigned procedures will be excluded. 2. Under 18 years of age. 3. Not a Penn State Student 4. Not participating in a collision sport. 5. Diagnosis of a learning disability impacting their capacity to consent. 6. History of ocular or neurological disease (glaucoma, macular degeneration, MS, Parkinson's) 7. Concussion diagnosis within the last calendar year. * However, if a subject sustains a concussion during the course of the study, they may remain as an active participant if they wish to do so.

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2024-03-18