Effectiveness of Adjuvant Continuous Lidocaine in General Anesthesia on Depth of Anesthesia (qCON), Pain Response (qNOX), and Blood Sugar Levels in Elective Primary Tumor Craniotomy Surgery

IndonesiaUAnes1001

This study aims to investigate the effect of adjuvant continuous lidocaine in General Anesthesia on Depth of Anesthesia (qCON), Pain Response (qNOX), and Blood Sugar Levels in Elective Primary Tumor Craniotomy Surgery

2023-01-16

2023-11-23

2024-01-10

Completed

60

Inclusion Criteria: * Adult patients aged 18 - 65 years with a diagnosis of brain tumor supratentorial who will undergo craniotomy by opening the dura * ASA physical status 1-3 * Surgery using a head pin * The level of consciousness was assessed with the Glasgow Coma Scale 15 Exclusion Criteria: 1. The patient's family or guardian refuses informed consent included in the research 2. The patient has atrioventricular block 3. There is a midline shift \> 5.4 mm 4. Diagnosis of glioblastoma multiforme or metastases 5. History of allergies to drugs used in the study 6. The patient routinely consumes or is administered class of drugs adrenergic agonists or antagonists (e.g., beta blockers, α-2 agonists, vasodilator, vasoconstrictor or inotropic). 7. The patient has been regularly consuming analgesic agents for the past 2 weeks. 8. The patient has a history of cardiac arrhythmia, kidney or liver disease based on the results of the history and confirmed by further examination. 9. Suffering from diabetes mellitus or taking anti-drugs hyperglycemia based on preoperative assessment.

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'DOUBLE', 'whoMasked': ['PARTICIPANT', 'INVESTIGATOR']}}, 'enrollmentInfo': {'count': 60, 'type': 'ACTUAL'}}

2024-02-16