Evaluation of the Benefit of Non-opioid General Anaesthesia on Postoperative Pain in Laparoscopic Colonic Surgery

2020-A02585-34

Evaluation of the benefit of non-opioid general anaesthesia on postoperative pain in laparoscopic colonic surgery

2020-12-17

2023-02-17

2023-02-17

Completed

160

Inclusion Criteria: * Patient over 18 years of age who has read and signed the consent form for participation in the study * Patient candidate for laparoscopic colectomy (planned or emergency) with possible conversion to laparotomy Exclusion Criteria: * Severe renal failure with baseline clearance\<30, hepatic failure with baseline PT\<40%, cardiac failure with LVEF\<20%. * Patient under court protection, guardianship or curatorship * Pregnant or breastfeeding patient * Patient not affiliated to the French social security system * Impossible to give the subject informed information and/or to give written informed consent: dementia, psychosis, disturbed consciousness, non-French speaking patient * Contraindication to anaesthesia or to the administration of one of the products used in the anaesthesia protocol * Patient participating in another interventional research or in a period of exclusion from a previous research

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'PARALLEL', 'interventionModelDescription': 'Single-centre prospective randomised study carried out in two parallel groups of patients undergoing laparoscopic colectomy.\n\n* Group 1: conventional general anaesthesia with morphine\n* Group 2: general anaesthesia without opiates', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'SINGLE', 'maskingDescription': 'The patient does not know which treatment is used for the anesthesia', 'whoMasked': ['PARTICIPANT']}}, 'enrollmentInfo': {'count': 160, 'type': 'ACTUAL'}}

2023-12-18