Clinical trial

Biological Bank for the Patients Followed in a Constitutive Reference Center for Autoimmune Cytopenia

Name
CHUBX 2018/13
Description
The Internal Medicine Department of Haut-Lévêque Hospital (Pr E LAZARO, Pr JL PELLEGRIN, Pr JF VIALLARD) was accredited in 2017 by the Ministry of Health as a Constitutive Reference Center for Autoimmune Cytopenia. The investigators wish to launch new research projects in autoimmune cytopenia and propose a translational and fundamental research based on collaboration between the clinical department, the biological resource center and the CNRS and INSERM research units ("Bedside to the Bench Strategy"). Thus, in the perspective of future research work, it seems imperative to set up a biological bank for the patients followed in our Reference Center.
Trial arms
Trial start
2019-02-02
Estimated PCD
2025-01-01
Trial end
2025-01-01
Status
Recruiting
Treatment
blood sample
45 ml whole blood for Peripheral blood mononuclear cell (PBMC) and monocytes isolation
Arms:
Autoimmune Cytopenia
urine sample
12 ml
Arms:
Autoimmune Cytopenia
Size
200
Primary endpoint
Number of patients with autoimmune cytopenia at diagnosis, or followed but not treated with a biological library (serum, plasma, DNA)
At baseline (Day 0)
Eligibility criteria
Inclusion Criteria: * Patients over 16 years old. * Patients with autoimmune cytopenia according to the definitions reported in the latest update of the French National Care Protocol (PNDS 2017). * Affiliated person or beneficiary of a social security scheme. * Free, informed and written consent signed by the participant and the investigator (at the latest on the day of inclusion and before any examination required by the research). Exclusion Criteria: * Positivity for HIV, Hepatitis C or B virus. * Pregnant or lactating woman. * Patient undergoing treatment for autoimmune cytopenia
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'CASE_ONLY', 'timePerspective': 'PROSPECTIVE'}, 'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': '45 ml whole blood for Peripheral blood mononuclear cell (PBMC) and monocytes isolation and urine sample'}, 'enrollmentInfo': {'count': 200, 'type': 'ESTIMATED'}}
Updated at
2024-02-13

1 organization

2 products

3 indications