Clinical trial

Study of Analgesic Action of Pregabalin, Duloxetine and Tramadol in Patients With Different Neuropathic Pain Phenotypes. Clinical Study

Name
3/28
Description
Chronic pain is the most frequent cause from which millions of patients suffer worldwide, which makes them unable to work but also greatly affects their quality of life. Chronic pain is a condition in itself. Neuropathic pain is a consequence of damage or disease of the peripheral or central nervous system and presents a heterogeneous clinical profile. A large number of pharmaceutical and non-pharmacological agents, as well as various complementary therapies, have been used in the treatment of neuropathic pain. However, their effectiveness is considered moderate and limited and is under investigation because a significant proportion of patients do not respond satisfactorily to treatment. Purpose: The purpose of the study is to investigate the effectiveness of analgesics in the different phenotypes of neuropathic pain.
Trial arms
Trial start
2018-03-05
Estimated PCD
2024-07-20
Trial end
2024-09-07
Status
Recruiting
Treatment
Pregabalin group
Pregabalin group
Arms:
Neuropathic pain patients
Duloxetine group
Duloxetine group
Arms:
Neuropathic pain patients
Size
100
Primary endpoint
NRS Scale assessment
1 month
Eligibility criteria
Inclusion Criteria: * neuropathic pain Exclusion Criteria: * under 18 years old * cancer pain * patients receiving pregabalin, duloxetine, tramadol * drug or alcohol abuse * psychiatric decease * renal failure, heart failure, liver failure, thrombocytopenia, closed-angle glaucoma
Protocol
{'studyType': 'OBSERVATIONAL', 'patientRegistry': True, 'targetDuration': '3 Months', 'designInfo': {'observationalModel': 'COHORT', 'timePerspective': 'PROSPECTIVE'}, 'enrollmentInfo': {'count': 100, 'type': 'ESTIMATED'}}
Updated at
2024-02-09

1 organization

2 products

1 indication

Product
Pregabalin
Product
Duloxetine