CHEK2
28 abstracts
Abstract
Germline alterations in patients with lung cancer.Org: Tempus Labs, Inc., Washington University School of Medicine, Washington University in Saint Louis,
Abstract
Clonal hematopoiesis in survivors of childhood cancer.Org: New York City, St Louis, Washington University School of Medicine, ModernaTX, St. Louis,
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Ancestry-adjusted genomic analysis to identify known and novel associations with single and multiple cancer phenotypes.Org: Memorial Sloan Kettering Cancer Center,
Abstract
Germline mutations and the presence of clonal hematopoiesis of indeterminate potential (CHIP) in 20,963 patients with BRCA-associated cancers.Org: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Tempus Labs, Inc., Johns Hopkins University Bloomberg School of Public Health, University of Minnesota Masonic Cancer Center, Minneapolis, MN,
Abstract
Prevalence of unexpected actionable germline pathogenic variants identified on broad-based multi-gene panel testing in a cohort of cancer patients.Org: University of Vermont Larner College of Medicine, Dana-Farber Cancer Institute,
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Comprehensive profiling of mutational signatures and machine learning and subtypes of homologous recombination deficiency.Org: Genome Insight Inc., Research Institute for Future Medicine, Division of Breast Surgery, Division of Breast and Endocrine Surgery, Samsung Medical Center,
Abstract
Multi-omic characterization of gastrointestinal stromal tumor (GIST) in a large real-world patient cohort.Org: Sylvester Comprehensive Cancer Center, Miami, FL, University of Miami Miller School of Medicine, Miami, FL, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Caris Life Sciences, Irving, TX, Lombardi Comprehensive Cancer Center,
Abstract
Integrated clinical, pathologic, and genetic data in a racially diverse hereditary breast cancer cohort.Org: Vanderbilt University Medical Center, Meharry Medical College, Nihon Medi-Physics, Vanderbilt-Ingram Cancer Center,
Abstract
Implementing a germline testing program using fingernail specimens for patients with hematologic malignancies and initial clinical findings.Org: Memorial Sloan Kettering Cancer Center,
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Frequency of pathogenic germline variants in cancer susceptibility genes in 841 renal cell carcinoma cases.Org: AcornMed Biotechnology Co., Ltd., Beijing, China,
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Impact of early testing and analysis of germline genetic mutation patterns in patients with breast cancer: A single institution experience.Org: Mercy Clinic Oncology- Fort Smith, Fort Smith, Arcus Biosciences,
Abstract
Implementation of universal pan-cancer germline genetic testing in an Arab population: The Jordanian Exploratory Cancer Genetics (Jo-ECAG) study.Org: King Hussein Cancer Center, Invitae, King Hussein Medical Center,
Abstract
Accuracy of a simplified sequencing and bioinformatics platform on genetic variant detection in patients with prostate cancer.Org: Icahn School of Medicine at the Mount Sinai Hospital, Integrated Medical Professionals, PLLC,
Abstract
Hereditary breast and ovarian cancer syndrome: A misnomer?Org: New York Medical College - Saint Michael's Medical Center, Weill Cornell Medicine and NewYork-Presbyterian Hospital, New York, NY,
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Spectrum of germline pathogenic variants among patients with cancer in Mexico.Org: Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán, Mexico City, Mexico, National Institute of Medical Sciences and Nutrition Salvador Zubirán, City of Hope National Medical Center, Latin American School of Oncology,
Abstract
Genetic testing outcomes and pathogenic germline mutation prevalence in renal cell carcinoma.Org: Rogel Comprehensive Cancer Center, University of Michigan, Department of Internal Medicine C, University Hospital Greifswald, Greifswald, Germany, Division of Metabolism, Endocrinology, and Diabetes,
Abstract
Eliminating barriers to uptake of germline genetic testing for patients with advanced cancer: The GTAC study.Org: University of Vermont Larner College of Medicine, University of Vermont Cancer Center, Invitae, University of Colorado Denver Anschutz Medical Center,
Abstract
Women with pathogenic variants in moderate penetrance breast cancer genes: How frequently do they meet high penetrance genetic testing criteria?Org: Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, Institute for Genomic Health, 23andMe Inc., Sunnyvale, CA,
Abstract
Utility of multi-gene panel-based germline analysis following genomic profiling and cascade testing in advanced solid tumors: An initial report of the BRANCH study.Org: National Cancer Center Hospital East, Kashiwa, Japan, National Cancer Center Hospital Japan East, Kashiwa, Japan, National Hospital Organization Shikoku Cancer Center, Department of Gastroenterology, Saitama Cancer Center, Saitama-Shi, Japan, Kanagawa Cancer Center,
Abstract
Disparities in minority patients with breast cancer under 40 years of age: A single center experience.Org: UT Austin Dell Medical School, Ascension Seton,
Abstract
Clinical synergy of universal paired tumor genomic and germline sequencing in an unselected, pan-cancer cohort of patients: Greater than the sum of the parts.Org: Invitae, Mayo Clinic, Mayo Clinic Cancer Center Scottsdale, Mayo Clinic in Arizona, Division of Gastroenterology and Hepatology, Mayo Clinic,
Abstract
Effect of somatic-germline genomic integration on the contribution of pathogenic germline genetic variants (gPV) to colorectal cancer (CRC) carcinogenesis.Org: Memorial Sloan Kettering Cancer Center, New York, NY, Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, New York, NY,
Abstract
Somatic hereditary gene panel analysis: A pilot study from Uzbekistan.Org: Vita Alliance Hospital, Tashkent, Uzbekistan,
Abstract
Prevalence of pathogenic variants in non-BRCA genes and their impact on clinical practice in Argentina.Org: Hospital Privado Universitario de Córdoba, CIMETSA-IUCBC,
Abstract
Homologous recombination-related (HRR) gene mutations in patients with glioma and their relevance to genomic characteristics, tumor mutation burden (TMB), and prognosis.Org: Jinan, China, Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd., The State Key Lab of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd, Nanjing, China,
Abstract
3D genomics identify alternate mechanisms of homologous recombination deficiency in uterine sarcoma.Org: Memorial Sloan Kettering Cancer Center, New York, NY, NYU Langone Health, New York, NY, King Edward Memorial Hospital, Perth, Australia,
Abstract
Clinical implications of universal germline testing in breast cancer patients in an Arab population: The Jordanian Exploratory Cancer Genetics (Jo-ECAG) study.Org: King Hussein Cancer Center, Amman, Jordan, Invitae, San Francisco, CA, King Hussien Cancer Center,
Abstract
Relations between mutant KRAS and TP53 subtypes and other co-mutations in pancreatic cancer.Org: Bridgeport Hospital, Yale New Haven Health, University of Pittsburgh, School of Medicine, Yale University Dept of Pathology, Yale University,