dexamethasone

Aliases
Aeroseb-Dex, Decaderm, Decadron, Dexasone, DM (1 other aliases)

30 clinical trials

79 abstracts

34 indications

Indication
COVID-19
Indication
Nausea
Indication
Nerve Block
Indication
Arthroplasty
Indication
Replacement
Indication
Shoulder
Indication
Spinal Disorder
Indication
Leukemia
Indication
Plasmacytoma
Indication
lymphoma
Indication
Anaemia
Indication
Fatigue
Indication
Prostate Cancer
Clinical trial
Optimal Dosing and Timing of Corticosteroids in Hospitalized Patients With COVID-19.
Status: Recruiting, Estimated PCD: 2024-12-01
Abstract
Phase 3 randomized study of isatuximab (Isa) plus lenalidomide and dexamethasone (Rd) with bortezomib versus isard in patients with newly diagnosed transplant ineligible multiple myeloma (NDMM TI).
Org: Université de Poitiers et Centre Hospitalier Universitaire de Poitiers, INSERM U1313 and CIC 1082, Poitiers, France, Hôpital Haut Leveque, University Hospital, Pessac, France, ECSTRA, Centre de Recherche en Epidémiologie et Statistiques, INSERM UMR 1153, Paris, France, Lille University Hospital, Lille, France, CHU de Toulouse, IUCT-O, Université de Toulouse, UPS, Service d’Hématologie, Toulouse, France,
Abstract
Safety results from the phase 3 MajesTEC-7 study in patients (pts) with transplant ineligible/not intended newly diagnosed multiple myeloma (NDMM).
Org: Centre Hospitalier Universitaire de Nantes, Ankara University, University of Athens, School of Medicine, Showa University, Memorial Sloan Kettering Cancer Center,
Abstract
Results from the randomized phase 3 DREAMM-8 study of belantamab mafodotin plus pomalidomide and dexamethasone (BPd) vs pomalidomide plus bortezomib and dexamethasone (PVd) in relapsed/refractory multiple myeloma (RRMM).
Org: Princess Margaret Cancer Centre, Ankara University, University Hospital Brno, General Hospital Evangelismos, Athens, Greece, St. Vincent's Hospital Melbourne,
Abstract
Tolerability and efficacy of BrECADD versus BEACOPP in advanced stage classical Hodgkin lymphoma: GHSG HD21, a randomized study.
Org: University Hospital of Cologne, Center for Integrated Oncology Aachen Bonn Cologne Düsseldorf (CIO ABCD), German Hodgkin Study Group (GHSG), Swiss Group for Clinical Cancer Research (SAKK), Department of Internal Medicine III with Hematology,
Abstract
All-oral triplet iberdomide, ixazomib, and dexamethasone in elderly patients with multiple myeloma at first relapse: Results of the IFM phase 2 study I2D.
Org: Centre Hospitalier Universitaire de Nantes, Centre Hospitalier Universitaire de Poitiers, Vendée Departmental Hospital Centre, Hopital Cote de Nacre, Hematology Department, University Cancer Institute IUCT oncopôle, Toulouse, France,
Abstract
Ambulatory teclistamab administration in patients with relapsed/refractory multiple myeloma.
Org: Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University,
Abstract
Subcutaneous epcoritamab (SC epcor) administered outpatient (outpt) for relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL): Results from phase 2 EPCORE NHL-6.
Org: Lehigh Valley Health Network, University of Oklahoma, Stephenson Cancer Center, H. Lee Moffitt Cancer Center at Memorial Healthcare System, Stony Brook University Medical Center,
Abstract
Phase 3 trial evaluating the efficacy and safety of odronextamab versus standard-of-care (SOC) therapy in relapsed/refractory (R/R) aggressive B-cell non-Hodgkin lymphoma (B-NHL; OLYMPIA-4).
Org: School of Public Health & Preventative Medicine, Monash University, Melbourne, Australia, Hospital Universitario Doctor Peset, Valencia, Spain, Hospital Virgen de las Nieves, Granada, Spain, Olivia Newton-John Cancer Wellness & Research Centre, Heidelberg, Australia, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea,
Abstract
Post-ASCT consolidation with EPD or ERD in patients with high-risk multiple myeloma.
Org: Hackensack University Medical Center, John Theurer Cancer Center at Hackensack Meridian Health, HMH School of Medicine, Hackensack, NJ,
Abstract
Epcoritamab + R-DHAX/C in transplant-eligible patients (pts) with high-risk relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL).
Org: Universitair Ziekenhuis Gent, Health Research Institute IIS-FJD, Lymphoma Service, Memorial Sloan Kettering Cancer Center,
Abstract
Frontline treatment with zanubrutinib plus rituximab (ZR) followed by short course R-DHAOx in patients with mantle cell lymphoma (MCL): Results of the phase II CHESS clinical trial.
Org: Department of Hematology, Huizhou Municipal Central Hospital, Department of Medical Oncology, The Second Hospital of Dalian Medical University, Department of Hematology, The First Affiliated Hospital of Guangdong Pharmaceutical University,
Abstract
Physical activity and dexamethasone for cancer related fatigue: A preliminary placebo controlled randomized control trial.
Org: The University of Texas MD Anderson Cancer Center, Houston, TX, USA,
Abstract
Prevention of pemetrexed-induced rash with low-dose dexamethasone in patients with NSCLC receiving immunotherapy: A prospective, single-arm clinical trial.
Org: Department of Oncology, the Second People's Hospital of Yibin, Yibin, China, Department of Oncology, the Second People's Hospital of Yibin, Yibin, SIchuan, China, Department of Oncology,the Second People's Hospital of Yibin City, Yibin, China,
Abstract
CYP11A1 inhibitor MK-5684 versus next-generation hormonal agent (NHA) switch in patients with metastatic castration-resistant prostate cancer (mCRPC) after NHA and taxane-based chemotherapy: Phase 3 MK-5684-003 trial.
Org: Fred Hutchinson Cancer Center, University of Washington and Fred Hutchinson Cancer Research Centre, Merck & Co., Inc., Rahway, NJ, University of Minnesota Masonic Cancer Center, Minneapolis, MN,
Abstract
Effect of daratumumab on light chain reduction in newly diagnosed multiple myeloma with light chain cast nephropathy.
Org: Weill Cornell Medicine and NewYork-Presbyterian Hospital, New York, NY, New York Oncology Hematology PC,
Abstract
Exposure-response analyses for optimal therapeutic dose selection of ABBV-383 in patients with relapsed/refractory multiple myeloma (RRMM).
Org: Levine Cancer Institute, Atrium Health, Wake Forest University School of Medicine, Froedtert & Medical College of Wisconsin Cancer Center,
Abstract
Analysis of real-world (RW) pomalidomide (pom) dosing patterns in patients (pts) with multiple myeloma (MM) from the Flatiron database.
Org: Myeloma, Waldenstrom’s and Amyloidosis Program, Section of Hematologic Malignancies and Cellular Therapy,
Abstract
Final results of a phase II study of lenalidomide-elotuzumab as maintenance therapy post-autologous stem cell transplant (AuSCT) in patients (Pts) with multiple myeloma (MM).
Org: The University of Texas MD Anderson Cancer Center, Stem Cell Transplantation Rsch, Houston, TX, GlaxoSmithKline,
Clinical trial
Towards a Self-Administered Hearing Protection Regimen
Status: Recruiting, Estimated PCD: 2024-10-01
Abstract
First phase 3 results from CARTITUDE-4: Cilta-cel versus standard of care (PVd or DPd) in lenalidomide-refractory multiple myeloma.
Org: University College London Cancer Institute, University Hospital of Salamanca/IBSAL/CIC/CIBERONC, Medical College of Wisconsin, Peter MacCallum Cancer Centre, Melbourne, Australia, Hematology Clinic,
Abstract
Carfilzomib, lenalidomide, and dexamethasone (KRd) versus elotuzumab and KRd in transplant-eligible patients with newly diagnosed multiple myeloma: Post-induction response and MRD results from an open-label randomized phase 3 study.
Org: Schleswig-Holstein University Hospital, Hospital Salzburg Paracelus University, University Hospital rechts der Isar, Jena University Hospital, Wuerzburg University Medical Center,
Abstract
Maintenance therapy with carfilzomib, pomalidomide, and dexamethasone (KPd) in high-risk myeloma patients (pts): A phase 2 study with a safety run-in.
Org: Winship Cancer Center of Emory University, Emory University, Atlanta, GA, USA, Emory University School of Medicine, Biostatistics Shared Resource, Winship Cancer Institute of Emory University,
Abstract
Final results of phase 2 trial of personal dendritic cell (DC) vaccines loaded with autologous tumor antigens (ATA) in newly diagnosed glioblastoma (GBM).
Org: University of California Irvine, University of California San Diego, University of California Irvine Department of Epidemiology and Biostatistics, Norton Cancer Institute, Rutgers Cancer Center,
Abstract
A phase 1 study of belantamab mafodotin in combination with standard of care in newly diagnosed multiple myeloma: An interim analysis of DREAMM-9.
Org: Memorial Sloan Kettering Cancer Center, Katedra i Klinika Hematoonkologii i Transplantacji Szpiku, Seoul National University Hospital, Hospital Quirón Madrid, University of Kansas Medical Center, Department of Biostatistics & Data Science,
Abstract
Adjusted indirect treatment comparison of progression-free survival (PFS) associated with DRd and VRd based on MAIA and SWOG S0777 individual patient-level data.
Org: Samuel Oschin Comprehensive Cancer Center, Department of Hematology, Mayo Clinic Rochester, Janssen Global Market Access, Janssen Scientific Affairs, Georgetown University Medical Center,
Abstract
Phase 1/2a study of PRL-02, a long-acting intramuscular (IM) depot injection of abiraterone decanoate, in patients (pts) with advanced prostate cancer.
Org: Carolina Urologic Research Center, Oncology Hematology Consultants Ltd., First Urology, Urology Cancer Center, PC, National Cancer Institute, Vilnius, Lithuania,
Abstract
A phase 3, two-stage, randomized study of mezigdomide, carfilzomib, and dexamethasone (MeziKd) versus carfilzomib and dexamethasone (Kd) in relapsed/refractory multiple myeloma (RRMM): SUCCESSOR-2.
Org: Dana-Farber Cancer Institute, Bristol Myers Squibb, Institute for Myeloma and Bone Cancer Research, Hematology Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, Catalan Institute of Oncology and Josep Carreras Institute,
Abstract
Phase 1 study of tasquinimod, an S100A9 inhibitor, alone and in combination with IRd for relapsed and refractory multiple myeloma (RRMM).
Org: Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, The Wistar Institute, Active Biotech,
Abstract
MajesTEC-9: A randomized phase 3 study of teclistamab versus pomalidomide, bortezomib, and dexamethasone or carfilzomib and dexamethasone in patients with relapsed/refractory multiple myeloma.
Org: Centre Hospitalier Universitaire de Nantes, Clinica São Germano, São Paulo, Brazil, Columbia University Medical Center, Sylvester Comprehensive Cancer Center, Miami, FL, Janssen Research & Development,
Abstract
OMNIA-2: Phase I/II study of ANV419, an IL-2R-βγ targeted antibody-IL-2 fusion protein, in patients with relapsed or refractory multiple myeloma.
Org: Anaveon, Institute of Medical Oncology, Department of Internal Medicine C, University Hospital Greifswald, Greifswald, Germany, Lillebaelt Hospital, University Hospital of Southern Denmark,
Abstract
Identification of genes encoding targets associated with adverse events in multiple myeloma.
Org: Kansas State University–Olathe, Taussig Cancer Center, Cleveland Clinic Taussig Cancer Instititute, University of Missouri Kansas City, Indiana University/Melvin and Bren Simon Cancer Center,
Abstract
Safety and preliminary efficacy of intrathecal (IT) and intravenous (IV) nivolumab (N) for patients (pts) with leptomeningeal disease (LMD).
Org: MD Anderson Cancer Center, University of Texas MD Anderson Cancer Center, U T MD Anderson Cancer Center, Department of Biostatistics, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan, The University of Texas MD Anderson Cancer Center, Stem Cell Transplantation Rsch, Houston, TX,
Abstract
Safety and clinical activity of belantamab mafodotin plus lenalidomide and dexamethasone in transplant ineligible patients with newly diagnosed multiple myeloma: The phase 1/2, prospective, open-label, BelaRd study.
Org: Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Attica, Greece, Health Data Specialists, Dublin, Ireland, Dublin, Ireland, Alexandra Hospital, Athens, Greece,
Abstract
Physical and emotional quality of life in children with B-acute lymphoblastic leukemia randomized to every 4- vs. 12-week vincristine/dexamethasone during maintenance: Children’s Oncology Group AALL0932.
Org: Children's Oncology Group Data Center, Yale University Hematology/Oncology, St. Jude Children's Research Hospital, Children's National Medical Center, Washington, DC, University of Texas Southwestern Medical Center,
Abstract
Phase 2 study of abatacept, ixazomib, and dexamethasone in patients with relapsed/refractory multiple myeloma.
Org: Roswell Park Comprehensive Cancer Center, IU Simon Comprehensive Cancer Center, Vanderbilt-Ingram Cancer Center,
Abstract
EXCALIBER-RRMM: A phase 3, two-stage study of iberdomide, daratumumab, and dexamethasone (IberDd) versus daratumumab, bortezomib, and dexamethasone (DVd) in patients (pts) with relapsed/refractory multiple myeloma (RRMM).
Org: Winship Cancer Center of Emory University, St. Vincent’s Hospital, University of Melbourne, National and Kapodistrian University of Athens, Clínica Universidad de Navarra and CIBEREHD,
Abstract
A phase 2 evaluation of daratumumab-based induction therapy in patients with multiple myeloma with severe renal insufficiency.
Org: Emory University School of Medicine and Winship Cancer Institute, UPMC Cancer Center - Hillman Cancer Center, Winship Cancer Institute of Emory University,
Abstract
Prevention of amivantamab infusion related reactions with extended pre-infusion day oral steroid therapy.
Org: Icon Cancer Centre, Singapore General Hospital and SingHealth Duke NUS Blood Cancer Center,
Abstract
Treatments and outcomes of patients with localized extranodal NK/T-cell lymphoma (ENKL) diagnosed between 2014 and 2021: A cooperative study in Japan.
Org: Mie University Graduate School of Medicine, Tsu, Japan, Shimane University Hospital, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Nagano Prefectural Shinshu Medical Center, National Cancer Center Hospital East, Kashiwa, Japan,
Abstract
Safety and efficacy of silibinin in patients with brain metastases after stereotactc radiosurgery: SUSTAIN trial.
Org: University of Florence, AOUC, Azienda Ospedaliera Universitaria Careggi, Istituto Fiorentino di Cura ed Assistenza, Istituto Fiorentino di Cura e Assistenza (IFCA),
Abstract
Bortezomib-induced cardiotoxicity: Real-world data from a single-center.
Org: LSU Health Shreveport, Louisiana State University Shreveport, Feist-Weiller Cancer Center at LSUHSC-Shreveport, Louisiana State University (Shreveport) Program at Feist-Weiller Cancer Center,
Abstract
Single center experience of using Anakinra prophylactically at Day 0 to reduce CD19 CART toxicities.
Org: Augusta University Georgia Cancer Center, University of Illinois Urbana-Champaign, College of Medicine, University of the Philippines - Manila, Medical College of Georgia, Augusta, GA, Department of Internal Medicine C, University Hospital Greifswald, Greifswald, Germany,
Abstract
Incidence of infusion related reactions of daratumumab-hyaluronidase-fihj: Pre-post intervention study of premedication omission.
Org: University of Chicago Medical Center, Chicago, IL, Center for Data Intensive Science at the University of Chicago, University of Chicago,
Abstract
Multi-omic characterization of gastrointestinal stromal tumor (GIST) in a large real-world patient cohort.
Org: Sylvester Comprehensive Cancer Center, Miami, FL, University of Miami Miller School of Medicine, Miami, FL, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Caris Life Sciences, Irving, TX, Lombardi Comprehensive Cancer Center,
Abstract
A phase I/II study of carfilzomib, iberdomide (CC-220), and dexamethasone (KID) in patients with newly diagnosed transplant-eligible multiple myeloma.
Org: John Theurer Cancer Center at Hackensack Meridian Health, HMH School of Medicine, Hackensack, NJ, Hackensack University Medical Center, Georgetown Lombardi Comprehensive Cancer Center, Center for Discovery and Innovation, Hackensack Meridian Health, Hackensack Meridian Health,
Abstract
Dexamethasone and exercise for cancer-related fatigue: A phase III randomized controlled trial.
Org: Tata Memorial Centre, Tata Memorial Hospital (HBNI), Tata Memorial Centre (HBNI),
Abstract
Comparing the time toxicity of cancer treatments in the CCTG LY.12 trial.
Org: University of Minnesota Masonic Cancer Center, Minneapolis, MN, Queen's University, Belfast, Princess Margaret - University Health Network, Canadian Cancer Trials Group, NCIC Clinical Trials Group,
Abstract
A phase IIb study of selinexor in combination with carfilzomib, daratumumab, or pomalidomide in patients with multiple myeloma relapsing on current therapy.
Org: John Theurer Cancer Center at Hackensack Meridian Health, HMH School of Medicine, Hackensack, NJ, Hackensack University Medical Center, Georgetown Lombardi Comprehensive Cancer Center, Center for Discovery and Innovation, Hackensack Meridian Health, Hackensack Meridian Health,
Abstract
ACCLAIM-1 dose escalation: Determination of quaratusugene ozeplasmid and osimertinib recommended phase 2 dose (RP2D).
Org: Valkyrie Clinical Trials, Inc, Rocky Mountain Cancer Centers, Millennium Oncology, Virginia Cancer Specialists, Genprex,
Abstract
External validation of venous thromboembolism risk prediction models in patients with multiple myeloma in a community setting: A retrospective cohort study.
Org: Saint Vincent Hospital Cancer Center Green Bay, University of Pittsburgh Medical Center Cancer Center, Saint Vincent Cancer and Wellness Center, Saint Vincent Hospital, Department of Hematology/Oncology, Internal Medicine, St. Vincent Hospital,
Abstract
Spectrum of germline pathogenic variants among patients with cancer in Mexico.
Org: Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán, Mexico City, Mexico, National Institute of Medical Sciences and Nutrition Salvador Zubirán, City of Hope National Medical Center, Latin American School of Oncology,
Abstract
A novel risk assessment metric for antimyeloma therapies and drug interactions.
Org: Kansas State University–Olathe, DATA Consortium, Computational Comparative Medicine, Department of Mathematics, Università degli Studi di Genova, San Martino, Italy, Myeloma Program,
Abstract
Management and outcomes of advanced stage cardiac AL amyloidosis in the daratumumab era.
Org: University of California, San Diego Center for Advanced Laboratory Medicine,
Abstract
Association of venetoclax-based therapy with increased survival in multiple myeloma (MM) harboring t(11;14): A single-center experience.
Org: H. Lee Moffitt Cancer Center and Research Institute, University of South Florida Morsani College of Medicine,
Abstract
Efficacy and safety of 40 mg vs 60 mg once weekly selinexor in combination with pomalidomide and dexamethasone in relapsed and/or refractory multiple myeloma (RRMM).
Org: Queen Elizabeth II Health Sciences Centre and Dalhousie University, David Geffen School of Medicine at UCLA, Banner MD Anderson Cancer Center, Division of Hematology/Oncology, Columbia University, Clalit Health Services, Ha’Emek Medical Center,
Abstract
Three years (yrs) maintenance with bortezomib, lenalidomide, and dexamethasone (RVD) in multiple myeloma (MM): Results of Total Therapy (TT) IIIB.
Org: University of Arkansas for Medical Sciences (UAMS), Jordan University of Science and Technology, University of Arkansas for Medical Sciences Winthrop P. Rockefeller Institute, Myeloma Center, The University of Arkansas for Medical Sciences/Arkansas Children’s Hospital,
Abstract
Ocular adverse events in transplant ineligible patients with newly diagnosed multiple myeloma treated with belantamab mafodotin plus lenalidomide/dexamethasone from the phase 1/2 BelaRd study.
Org: Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Attica, Greece, Health Data Specialists, Dublin, Ireland, Dublin, Ireland, Alexandra Hospital, Athens, Greece, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Attica, Greece, Health Data Specialists, Dublin, Ireland, Alexandra Hospital, Athens, Greece,
Abstract
Outcomes with bendamustine lymphodepletion prior to brexucabtagene autoleucel for mantle cell lymphoma.
Org: Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA,
Abstract
Bendamustine-bortezomib-dexamethasone in relapsed/refractory multiple myeloma.
Org: Hematology Unit, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, University Federico II, Cimitile, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRST (IRCCS) s,
Abstract
Real-world analysis of D-RVd v. RVd at induction for newly diagnosed transplant eligible multiple myeloma patients.
Org: HealthTree Foundation, The University of Utah Huntsman Cancer Institute, Salt Lake City, UT,
Abstract
Effectiveness of anti-B-cell maturation antigen (BCMA)-targeting therapy after selinexor treatment.
Org: Vanderbilt University Medical Center, Hematology Department, Hospital Universitari i Politècnic La Fe, CHU Nantes-Department of Hepato-Gastroenterology, University of North Carolina School of Medicine, University of Wisconsin Health,
Abstract
Racial differences in outcomes of patients with relapsed/refractory multiple myeloma treated with selinexor.
Org: Michigan State University, Karmanos Cancer Institute, McLaren Greater Lansing, Michigan State University College of Human Medicine, Michigan State University - College of Osteopathic Medicine,
Abstract
Incidence of second primary malignancies (SPMs) in patients with multiple myeloma (MM) receiving anti-CD38 monoclonal antibodies (mAbs): A systematic review and meta-analysis.
Org: Department of Internal Medicine, Cleveland Clinic, Cleveland, OH, Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ, Massachusetts General Hospital, Boston, MA, USA, The University of Arizona, Tucson, AZ, Faculty of Health Sciences, Hamilton, ON, Canada,