Indication
Monkeypox
13 clinical trials
10 products
1 drug
Product
BNT166aClinical trial
A Randomized, Partially Observer-blind, Dose-escalation, Phase I/II Trial Evaluating the Safety and Immunogenicity of Investigational RNA-based Mpox Vaccine CandidatesStatus: Recruiting, Estimated PCD: 2024-10-01
Clinical trial
A Randomized, Placebo-Controlled, Double-Blinded Trial of the Safety and Efficacy of Tecovirimat for the Treatment of Human Monkeypox Virus DiseaseStatus: Recruiting, Estimated PCD: 2025-05-30
Product
TecovirimatProduct
PlaceboClinical trial
A Phase 2 Randomized, Open-Label, Multisite Trial to Inform Public Health Strategies Involving the Use of MVA-BN Vaccine for MpoxStatus: Active (not recruiting), Estimated PCD: 2024-07-01
Product
JYNNEOSClinical trial
Placebo-controlled Randomized Trial of Tecovirimat in Non-hospitalized Patients With Monkeypox: Canadian Feasibility Study (PLATINUM-CAN)Status: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
Follow-up of People at Risk of Monkeypox Infection: a Prospective Cohort StudyStatus: Active (not recruiting), Estimated PCD: 2024-10-01
Product
IMVANEX + JYNNEOSClinical trial
Cohort Events Monitoring (CEM) Study for the Assessment of Safety Profile of MVA-BN (Jynneos) Vaccine in Adult Personnel and Staff in the PALM-007 Study in Democratic Republic Of The CongoStatus: Recruiting, Estimated PCD: 2024-07-01
Product
MVA-BN vaccineClinical trial
Randomized Trial to Evaluate the Efficacy/Effectiveness, Safety, and Immunogenicity of Replicative Live Attenuated Vaccinia Virus Vaccine LC16m8 for Prevention Against Mpox in High-risk Populations During Vaccination Deployment in ColombiaStatus: Recruiting, Estimated PCD: 2024-08-22
Product
LC16m8Clinical trial
A Phase III, Multi-country, Randomized, Placebo-controlled, Double-blinded Trial to Assess the Efficacy and Safety of Tecovirimat Antiviral Treatment for Patients With Monkeypox Virus DiseaseStatus: Recruiting, Estimated PCD: 2024-01-01
Drug
VarlilumabClinical trial
A Phase 2 Randomized, Open-Label, Multisite Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN VaccineStatus: Active (not recruiting), Estimated PCD: 2022-12-01
Clinical trial
European Randomised Clinical Trial on mPOX InfectionStatus: Not yet recruiting, Estimated PCD: 2026-12-01
Clinical trial
An Open, Simple, Randomized Study of the Safety, Tolerability, Pharmacokinetics of NIOCH-14 in Volunteers Aged 18-50 Years in Parallel GroupsStatus: Completed, Estimated PCD: 2021-02-27
Product
NIOCH-14Clinical trial
A Randomized, Placebo-controlled, Double-blinded Trial of the Safety and Efficacy of Tecovirimat for the Treatment of Adult and Pediatric Patients With Monkeypox Virus DiseaseStatus: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
SMART (Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster Randomized Controlled Trial)Status: Not yet recruiting, Estimated PCD: 2024-12-01