Indication
Central Nervous System Diseases
22 clinical trials
20 products
3 drugs
Clinical trial
An Open-Label Extension of the Study XEN496 in Children With KCNQ2 Developmental and Epileptic EncephalopathyStatus: Terminated, Estimated PCD: 2023-11-17
Product
PlaceboProduct
XEN496Clinical trial
Phase 1b Open-Label, Dose-Identification Study of XPro1595 in Patients With Alzheimer's Disease and Biomarkers of Inflammation.Status: Completed, Estimated PCD: 2021-06-30
Product
XPro1595Clinical trial
Global Study to Investigate Safety and Efficacy of Donanemab in Early Symptomatic Alzheimer's DiseaseStatus: Recruiting, Estimated PCD: 2027-04-16
Product
DonanemabProduct
ACI-35.030Clinical trial
A Phase Ib/IIa Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability and Immunogenicity of Different Doses, Regimens and Combinations of Tau Targeted Vaccines in Subjects With Early Alzheimer's DiseaseStatus: Completed, Estimated PCD: 2023-09-05
Product
JACI-35.054Clinical trial
An Open Label Extension of XPro1595 in Patients With Alzheimer's Disease That Have Completed a Phase 1 or Phase 2 Study With XPro1595Status: Recruiting, Estimated PCD: 2026-05-04
Clinical trial
A Phase 3 Study of Adjunctive XEN496 in Pediatric Subjects With KCNQ2 Developmental and Epileptic EncephalopathyStatus: Terminated, Estimated PCD: 2023-05-16
Clinical trial
A Phase 2, Randomized, Placebo-Controlled, Double-Blind Study of XPro1595 in Patients With Mild Cognitive Impairment (MCI) With Biomarkers of InflammationStatus: Withdrawn, Estimated PCD: 2023-10-26
Clinical trial
A Multi-Center, Phase II, Randomized, Double-Blind, Prospective, Active Placebo- Controlled Trial of Sub-Anesthetic Intravenous Infusion of Ketamine to Treat Levodopa- Induced Dyskinesia in Subjects With Parkinson's DiseaseStatus: , Estimated PCD: 2023-12-30
Product
MidazolamProduct
KetamineClinical trial
General Anesthesia for Endovascular Thrombectomy; A Pilot Study.Status: Completed, Estimated PCD: 2020-12-01
Product
SevofluraneProduct
LidocaineClinical trial
Nummular Headache Iberian Study on the Treatments and Outcomes in Real-World SettingStatus: Recruiting, Estimated PCD: 2024-12-31
Product
Clinical evaluationClinical trial
Higher-Than-Replacement Testosterone Plus Finasteride Treatment After SCIStatus: Terminated, Estimated PCD: 2021-08-13
Product
Testosterone EnanthateDrug
FinasterideClinical trial
Locomotor Training With Testosterone to Promote Bone and Muscle HealthStatus: Recruiting, Estimated PCD: 2025-01-30
Clinical trial
Gadopiclenol Pharmacokinetics, Safety and Efficacy in Pediatric Patients < 2 Years of AgeStatus: Recruiting, Estimated PCD: 2024-07-31
Product
GadopiclenolClinical trial
Investigating the Effect of Different Donanemab Dosing Regimens on ARIA-E and Amyloid Lowering in Adults With Early Symptomatic Alzheimer's DiseaseStatus: Recruiting, Estimated PCD: 2024-06-01
Drug
VarlilumabClinical trial
Donanemab Follow-On Study: Safety, Tolerability, And Efficacy in Symptomatic Alzheimer's Disease With Validation of Remote Neuropsychological AssessmentsStatus: Completed, Estimated PCD: 2024-02-27
Clinical trial
Evaluation of the Safety, Tolerability, Efficacy and Activity of AMX0035, a Fixed Combination of Phenylbutyrate (PB) and Tauroursodeoxycholic Acid (TUDCA), for the Treatment of ALSStatus: Completed, Estimated PCD: 2019-09-25
Product
AMX0035Clinical trial
Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke (EXTEND-AGNES TNK)Status: Not yet recruiting, Estimated PCD: 2027-08-30
Product
TenecteplaseClinical trial
Evaluation of a Combined Analysis of Serum and Cerebrospinal Fluid Inflammatory Biomarkers to Help in Etiological Diagnosis of Central Nervous System Autoimmune DiseasesStatus: Recruiting, Estimated PCD: 2023-04-01
Product
Data analysisClinical trial
Role and Mechanism of Bifidobacterium Triple Viable Capsules in Improving Motor Symptoms in Patients With Mild to Moderate Parkinson's Disease: a Multicenter Randomized Clinical StudyStatus: Recruiting, Estimated PCD: 2023-10-01
Clinical trial
A Real-world Study on the Effectiveness and Safety of Butylphthalide in the Treatment of Ischemic Stroke.Status: Recruiting, Estimated PCD: 2025-09-01
Product
ButylphthalideClinical trial
Phase 1 Trial of Engineered HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsStatus: Active (not recruiting), Estimated PCD: 2025-09-01
Product
G207Clinical trial
An Open-label Multicenter Phase 1b-2 Study of Elacestrant in Combination With Abemaciclib in Women and Men With Brain Metastasis From Estrogen Receptor Positive, HER-2 Negative Breast CancerStatus: Recruiting, Estimated PCD: 2025-12-01
Drug
ElacestrantProduct
Abemaciclib