Indication
Neuromuscular Blockade
21 clinical trials
17 products
1 drug
Clinical trial
A Phase 4 Double-blinded, Randomized, Active Comparator-controlled Clinical Trial to Study the Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 YearsStatus: Completed, Estimated PCD: 2023-09-21
Product
SugammadexProduct
Neostigmine + GlycopyrrolateProduct
Neostigmine + AtropineProduct
BX1000Product
Rocuronium BromideClinical trial
A Phase 2, Randomized, Double-Blind, Active-Controlled, Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing SurgeryStatus: Completed, Estimated PCD: 2023-04-10
Clinical trial
Postoperative Urinary Retention After Reversal of Neuromuscular Block by Neostigmine Versus Sugammadex in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2026-09-01
Product
NeostigmineClinical trial
An Observational Study on the Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic SurgeryStatus: Not yet recruiting, Estimated PCD: 2025-01-31
Clinical trial
Rocuronium vs Cis-atracurium: Do Rocuronium Still 'ROCKS' In Coronary Artery Bypass GraftingStatus: Completed, Estimated PCD: 2023-11-23
Product
NimbexClinical trial
Comparison of Time to Full Recovery From Muscle Paralysis (TOF>0.9) and Extubation Using Sugammadex Versus Neostigmine/Glycopyrrolate in Patients With Pulmonary Disease in the Outpatient Bronchoscopy SuiteStatus: Completed, Estimated PCD: 2023-07-30
Product
neostigmine/glycopyrrolateProduct
sugammadexClinical trial
Deep Versus Moderate Neuromuscular Blockade During Total HIP Replacement Surgery to Improve POstoperative Quality of Recovery and Immune Function: a Randomized Controlled StudyStatus: Recruiting, Estimated PCD: 2024-05-01
Product
RocuroniumClinical trial
An Assessor-blinded, Randomized, Controlled, Single Center, Parallel Design Trial With Patient Masking to Compare Early Postoperative Gastric Emptying Associated With Rocuronium Neuromuscular Reversal With Sugammadex Versus Neostigmine in Adults Undergoing Colon and Rectal SurgeryStatus: Active (not recruiting), Estimated PCD: 2023-07-14
Clinical trial
A Blinded Randomized Study of Neostigmine/Glyco-pyrrolate 50 Mikrogram/kg or Sugammadex 2 mg/kg for Reversal of Neuromuscular Blockade in Elderly Patients (≥ 75 Years)Status: Recruiting, Estimated PCD: 2024-10-01
Clinical trial
Postoperative Urinary Retention in Patients After Noncardiac Surgery and Reversal of Neuromuscular Block by Neostigmine or Sugammadex: A Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
Reversal of Neuromuscular Blockade in Patients With Severe Renal ImpairmentStatus: Completed, Estimated PCD: 2022-08-11
Product
Cisatracurium + NeostigmineProduct
Rocuronium + SugammadexClinical trial
Reversal of Neuromuscular Blockade During the General AnaesthesiaStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
A Double-blinded, Randomized, Parallel Design Study to Compare the Effect of Deep Block Versus Moderate Block on the Stress Response After Laparoscopic GastrectomyStatus: Completed, Estimated PCD: 2017-06-14
Product
Deep BlockClinical trial
Effect of Neuromuscular Reversal Agents on Time for Neurological Assessment After Endotracheal Intubation in Critically Ill PatientsStatus: Not yet recruiting, Estimated PCD: 2025-08-14
Clinical trial
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of CareStatus: Completed, Estimated PCD: 2019-11-01
Product
POPSClinical trial
The Use of Sugammadex as Rescue Therapy Following Inadequate Reversal With NeostigmineStatus: Recruiting, Estimated PCD: 2024-07-01
Drug
VarlilumabClinical trial
Comparison of Efficacy of Sugammadex Versus Neostigmine in Reversing Neuromuscular Blocks in Patients Having Outpatient Endoscopic Retrograde Cholangiopancreatography (ERCP). A Randomized, Double-Blinded TrialStatus: Not yet recruiting, Estimated PCD: 2025-10-31
Clinical trial
Partial Neuromuscular Blockade in Acute Respiratory Distress SyndromeStatus: Terminated, Estimated PCD: 2023-03-01
Product
Neuromuscular blockadeClinical trial
Interaction Between Intravenous Magnesium Sulphate and Neostigmine or Sugammadex for the Reversal of a Rocuronium-induced Neuromuscular Block - A Randomized, Double Blinded, Electrophysiological StudyStatus: Completed, Estimated PCD: 2023-04-12
Product
Magnesium SulfateClinical trial
Interaction Between Intravenous Magnesium Sulfate and Volatile Anesthetics Compared to Propofol. A Three-center Prospective Randomized Single-blinded Electrophysiological StudyStatus: Recruiting, Estimated PCD: 2025-08-31
Clinical trial
The Effects of Nondepolarizing Muscle Relaxants During General Anesthesia on Perioperative and Postoperative Bleeding in Pediatric and Adult Patients Undergoing TonsillectomyStatus: Recruiting, Estimated PCD: 2025-06-30