Indication
Noonan syndrome
11 clinical trials
13 products
2 drugs
Clinical trial
A Study Evaluating the Safety and Efficacy of Once-weekly Dosing of Somapacitan in a Basket Study Design in Paediatric Participants With Short Stature Either Born Small for Gestational Age or With Turner Syndrome, Noonan Syndrome or Idiopathic Short StatureStatus: Recruiting, Estimated PCD: 2024-11-15
Product
SomapacitanClinical trial
A Study Comparing the Effect and Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® as Well as Evaluating Long-term Safety of Somapacitan in a Basket Study Design in Children With Short Stature Either Born Small for Gestational Age or With Turner Syndrome, Noonan Syndrome, or Idiopathic Short StatureStatus: Recruiting, Estimated PCD: 2024-05-20
Product
Norditropin®Product
somatropinClinical trial
Post Marketing Surveillance on Long-term Use With Norditropin® (Short Stature Due to Noonan Syndrome)Status: Completed, Estimated PCD: 2022-01-18
Product
SomatropinClinical trial
Genetic Testing of Noonan Subjects Previously Treated With Norditropin® in the GHNOO-1658 TrialStatus: Completed, Estimated PCD: 2008-10-01
Clinical trial
French Registry of Children Treated With Norditropin® for Short Stature Associated With Noonan SyndromeStatus: , Estimated PCD: 2028-03-17
Product
NorditropinClinical trial
A Trial to Assess the Safety and Efficacy of Epcoritamab-containing Combination Salvage Therapy Followed by Autologous Stem Cell Transplantation and Epcoritamab Consolidation in Patients With Relapsed Large B-cell LymphomaStatus: Not yet recruiting, Estimated PCD: 2026-11-01
Drug
EpcoritamabClinical trial
Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell LymphomaStatus: Recruiting, Estimated PCD: 2025-01-01
Product
131-I ApamistamabProduct
CAR T-cellClinical trial
A Phase 2 Study of Acalabrutinib in Combination With Lisocabtagene Maraleucel in Relapsed/Refractory Aggressive B-cell LymphomasStatus: Recruiting, Estimated PCD: 2025-03-01
Product
ACALABRUTINIBProduct
Lisocabtagene maraleucelProduct
Lymphodepleting chemotherapyClinical trial
A Phase I Study of T-cell Receptor Alpha Constant (TRAC) Locus Integrated CD19-Targeted 19(T2)28z1xx Chimeric Antigen Receptor (CAR) Modified T Cells in Adult Patients With CD19+ Relapsed or Refractory Large B-Cell LymphomaStatus: Recruiting, Estimated PCD: 2025-02-23
Product
19(T2)28z1xx TRAC T cellClinical trial
Constitution of a Biological Collection to Study the Pathophysiology in Noonan Syndrome and to Identify Predictive Factors of Disease ProgressionStatus: Recruiting, Estimated PCD: 2027-01-26
Product
Blood and Urine SamplingClinical trial
Treatment With HMG-COA Reductase Inhibitor (Simvastatin) of Growth and Bone Abnormalities in Children With Noonan Syndrome: A Phase III Randomised, Double Blind, Placebo-controlled Therapeutic TrialStatus: Completed, Estimated PCD: 2023-03-03
Product
SimvastatinDrug
Varlilumab