Indication
Grade IV
9 clinical trials
16 products
4 drugs
Clinical trial
Phase 2 Study of Olutasidenib With Temozolomide as Maintenance Therapy in Pediatric and Young Adult Patients Newly Diagnosed With High-Grade Glioma (HGG), Including Diffuse Intrinsic Pontine Glioma (DIPG), Which Harbor IDH1 MutationsStatus: Not yet recruiting, Estimated PCD: 2029-06-01
Product
OlutasidenibClinical trial
A Phase I/IIa Open Label Multicenter, Non-Randomized, Trial to Assess the Safety and Efficacy of CYNK-001in Combination With Recombinant Human Interleukin-2 in Adults With Recurrent Resection Eligible IDH1 Wild-type GlioblastomaStatus: Withdrawn, Estimated PCD: 2024-02-01
Product
CYNK-001Clinical trial
ATTAC-II: A Phase II Randomized, Blinded, and Placebo-controlled Trial of CMV RNA-Pulsed Dendritic Cells With Tetanus-Diphtheria Toxoid Vaccine in Patients With Newly-Diagnosed GlioblastomaStatus: Completed, Estimated PCD: 2023-11-30
Product
pp65-shLAMP DC with GM-CSFProduct
unpulsed PBMC and salineProduct
TdProduct
SalineProduct
pp65-flLAMP DCClinical trial
Phase I/II Clinical Trial of Allogeneic Cytomegalovirus-specific T Cells in Combination With Pembrolizumab for Recurrent and Newly Diagnosed Glioblastoma MultiformeStatus: Recruiting, Estimated PCD: 2026-04-01
Product
PembrolizumabClinical trial
A Phase II Study of Checkpoint Blockade Immunotherapy in Patients With Somatically Hypermutated Recurrent WHO Grade 4 GliomaStatus: , Estimated PCD: 2025-05-31
Drug
LurbinectedinDrug
T-VECClinical trial
Phase 0/I Dose Escalation Study of Mycophenolate Mofetil Combined With Radiation Therapy in GlioblastomaStatus: Recruiting, Estimated PCD: 2024-10-01
Product
TMZClinical trial
A Phase II Randomized Controlled Trial for the Addition of Chloroquine, an Autophagy Inhibitor, to Concurrent Chemoradiation for Newly Diagnosed GlioblastomaStatus: Withdrawn, Estimated PCD: 2023-11-10
Product
ChloroquineClinical trial
A Phase IB Study to Use Tadalafil to Overcome Immunosuppression During Chemoradiotherapy for IDH-wildtype Grade III-IV AstrocytomaStatus: Completed, Estimated PCD: 2023-06-07
Product
TadalafilClinical trial
Evaluation of Overcoming Limited Migration and Enhancing Cytomegalovirus-specific Dendritic Cell Vaccines With Adjuvant TEtanus Pre-conditioning in Patients With Newly-diagnosed GlioblastomaStatus: Completed, Estimated PCD: 2020-10-31
Product
Unpulsed DCsProduct
111In-labeled DCsDrug
VarlilumabProduct
Basiliximab