Indication
Grade IV Astrocytoma
4 clinical trials
7 products
1 drug
Clinical trial
An Open-Label Non-Randomized, Multi-Center Phase-2 Study of Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive GlioblastomaStatus: Completed, Estimated PCD: 2019-09-12
Product
MDNA55Clinical trial
A Phase Ib Clinical Trial to Evaluate Early Immunologic Pharmacodynamic Parameters Following Neoadjuvant Anti-PD-1 (Nivolumab), or the Combination of Anti-PD-1 Plus Anti-CTLA-4 (Nivolumab Plus Ipilimumab) in Patients With Surgically Accessible GlioblastomaStatus: Active (not recruiting), Estimated PCD: 2024-06-30
Product
Nivolumab-PlaceboDrug
T-VECProduct
Ipilimumab-PlaceboProduct
IpilimumabClinical trial
Phase I Study of Escalated Pharmacologic Dose, of Oral Folinic Acid in Combination With Temozolomide, According to Stupp R. Regimen, in Patients With Operated Grade-IV Astocytoma and a Non-methylated Gene Status of MGMT.Status: Terminated, Estimated PCD: 2019-12-12
Product
TMZProduct
Folinic acidClinical trial
A Phase IB Study to Use Tadalafil to Overcome Immunosuppression During Chemoradiotherapy for IDH-wildtype Grade III-IV AstrocytomaStatus: Completed, Estimated PCD: 2023-06-07
Product
Tadalafil