Indication
Tobacco use disorder
35 clinical trials
32 products
2 drugs
Clinical trial
A Randomized, Double-Blind, Placebo-Controlled, Crossover Design Study of CERC-501 in a Human Laboratory Model of Smoking BehaviorStatus: Completed, Estimated PCD: 2016-09-13
Product
PlaceboProduct
CERC-501Clinical trial
Imaging the Neurochemistry of Drug Addiction With PETStatus: Recruiting, Estimated PCD: 2024-09-01
Drug
cannabisClinical trial
Metabolism Informed Smoking Treatment in Medicaid and Medicare Patients: The MIST RCTStatus: Active (not recruiting), Estimated PCD: 2025-11-01
Product
Nicotine Replacement TherapyProduct
VareniclineClinical trial
The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With AbstinenceStatus: Recruiting, Estimated PCD: 2026-06-01
Product
AB-free kavaClinical trial
PARQuit Smoking Cessation Intervention for Adults With Serious Mental IllnessStatus: Recruiting, Estimated PCD: 2025-07-01
Product
BupropionClinical trial
Biomarkers of Exposure and Effect in Standardized Research E-cigarette (SREC) UsersStatus: Recruiting, Estimated PCD: 2024-07-19
Product
Nicotine Mini-LozengeClinical trial
Treating Nicotine Addiction in Caregivers of Children at American Family Children's HospitalStatus: Recruiting, Estimated PCD: 2024-10-01
Product
Nicotine ReplacementClinical trial
A Translational Randomized Clinical Trial of Varenicline Sampling to Promote Smoking Cessation and Scalable Treatment DisseminationStatus: Recruiting, Estimated PCD: 2025-03-01
Clinical trial
Measurement of Pulmonary Inflammation Using 18F-NOS Positron Emission Tomography (PET/CT) in E-cigarette UsersStatus: Recruiting, Estimated PCD: 2024-10-23
Product
[18F]NOSClinical trial
Reducing Tobacco-associated Lung Cancer Risk: A Randomized Clinical Trial of AB-free KavaStatus: Recruiting, Estimated PCD: 2024-11-01
Product
KavaClinical trial
Varenicline and Mobile Behavioral Assistance for Tobacco Cessation in HIV Care in IndiaStatus: Recruiting, Estimated PCD: 2025-07-20
Clinical trial
Impact of Low Nicotine Cigarette Messaging on Risk Perceptions and Hypothetical Tobacco and Nicotine Product Choices.Status: Completed, Estimated PCD: 2022-08-24
Clinical trial
Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer ScreeningStatus: Completed, Estimated PCD: 2024-01-31
Product
NicotineClinical trial
Integrating Financial Coaching and Smoking Cessation Coaching for People With Low Income Who Smoke: a Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2026-10-01
Clinical trial
Improving the Quality of Smoking Cessation and Shared Decision Making for Lung Cancer Screening: A Cluster Randomized TrialStatus: Recruiting, Estimated PCD: 2025-02-28
Clinical trial
Acetylcholine, Tobacco Smoking, Genes and Nicotinic ReceptorsStatus: Completed, Estimated PCD: 2021-12-01
Product
PhysostigmineClinical trial
Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and ChildrenStatus: Recruiting, Estimated PCD: 2025-06-02
Product
ProgesteroneClinical trial
Mechanisms Linking Obsessive-Compulsive Symptoms and Tobacco DependenceStatus: Completed, Estimated PCD: 2023-03-23
Product
CigaretteProduct
Cigarette 2Product
Patch 1Product
Patch 2Clinical trial
The Neural Mechanisms Associated With Alcohol and Cigarette Craving in Alcohol Use Disorder Smokers During Oxytocin TreatmentStatus: Completed, Estimated PCD: 2024-04-02
Product
OxytocinDrug
VarlilumabClinical trial
STUDY 2: CLINICAL PROTOCOL Metabolism of NNK Among Japanese AmericansStatus: Recruiting, Estimated PCD: 2021-10-15
Clinical trial
BREATHE 2 Cluster-randomized Trial of Health System Changes to Increase Reach of Smoking Cessation TreatmentsStatus: , Estimated PCD: 2024-10-01
Product
Wisconsin Tobacco QuitLineProduct
Primary Care ProviderClinical trial
Smoking Cessation Intervention for Depressed Smokers: Treatment DevelopmentStatus: Active (not recruiting), Estimated PCD: 2026-06-30
Product
BREATHE 2 Cessation StudyClinical trial
Isradipine Enhancement of Virtual Reality Cue Exposure for Smoking CessationStatus: Completed, Estimated PCD: 2023-06-14
Product
IsradipineClinical trial
A Test of Short and Long Term Naturalistic Outcomes of Smokers Who Sample Smokeless TobaccoStatus: Completed, Estimated PCD: 2016-03-01
Clinical trial
The Effect of Nicotine Exposure on Periodontal Tissues After Non- Surgical Periodontal Therapy With and Without the Use of a Chlorhexidine-based Antiseptic in Patients With PeriodontitisStatus: Active (not recruiting), Estimated PCD: 2023-10-16
Product
ChlorhexidineClinical trial
The Influence of Nicotinic Hepatic Metabolism on Neuroreceptor Substrates of Nicotine AddictionStatus: Active (not recruiting), Estimated PCD: 2025-11-22
Product
2-[18F]-FA PET/CTClinical trial
High Dose Bupropion Treatment for Smoking Cessation - Pilot StudyStatus: Terminated, Estimated PCD: 2023-07-01
Clinical trial
CPT-SMART for Treatment of PTSD and Cigarette SmokingStatus: Recruiting, Estimated PCD: 2024-09-30
Clinical trial
A Pilot SMART Pre- and Post-testing of an Integrative Mindfulness-Based Smoking Cessation Intervention for HIV PatientsStatus: Recruiting, Estimated PCD: 2024-12-09
Clinical trial
A Personalized mHealth Approach to Smoking Cessation for Veterans Living With HIV (CDA 17-005)Status: Completed, Estimated PCD: 2021-07-15
Clinical trial
An MRI Study of Neural Activity Following Exposure to a Specific Substance in Young Cigarette SmokersStatus: Recruiting, Estimated PCD: 2024-03-31
Product
Study AgentClinical trial
Assessing the Effect of Glucobrassicin-Rich Brussels Sprouts on the Metabolism of Deuterated Phenanthrene: Developing Food-Based Chemoprevention of Tobacco-Related Lung CancerStatus: Completed, Estimated PCD: 2021-03-22
Product
Deuterated PhenanthreneClinical trial
Efficacy of Naltrexone in Women's Smoking CessationStatus: Completed, Estimated PCD: 2009-06-01
Product
NaltrexoneClinical trial
Optimizing Smoking Cessation for People With HIV/AIDS Who SmokeStatus: Completed, Estimated PCD: 2021-04-01
Clinical trial
Mindfulness Training Plus Oxytocin to Reduce Smoking and Craving Among Smokers in WithdrawalStatus: Terminated, Estimated PCD: 2023-12-31