Indication
Menopause
47 clinical trials
60 products
3 drugs
Clinical trial
PhytoSERM for Menopausal Hot Flashes and Sustained Brain Health: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Clinical TrialStatus: Recruiting, Estimated PCD: 2024-11-15
Product
PlaceboProduct
Menopausal hormone therapyClinical trial
Treatment Patterns of Menopausal Hormone Therapy in South Korea: a Nationwide Cohort StudyStatus: Active (not recruiting), Estimated PCD: 2024-05-31
Product
NOE-115Clinical trial
A Phase 2a, 4-Week, Single Arm, Open-label, Multi-center Study to Assess Safety, Tolerability, and Preliminary Efficacy of NOE-115 in Women With Vasomotor Symptoms Due to MenopauseStatus: Recruiting, Estimated PCD: 2025-04-30
Clinical trial
Randomized, Double-Blind, Plac.-Controlled Clinical Study to Compare the Efficacy of FP-101 60mg b.i.d. vs. Placebo for the Treatment of Moderate-to-Severe Hot Flashes in Peri- and Post-menopausal Women Over a Period of 1-Week.Status: Completed, Estimated PCD: 2023-04-05
Product
EstetrolClinical trial
A Randomized Double-blind Placebo Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study II)Status: Completed, Estimated PCD: 2022-08-18
Clinical trial
A Randomized, Placebo-Controlled, Double-Blind, Dose-Ranging, Phase 2b Study to Investigate the Efficacy of ESN364 in Postmenopausal Women Suffering From Vasomotor Symptoms (Hot Flashes)Status: Completed, Estimated PCD: 2018-09-19
Product
FezolinetantProduct
FP-101Product
ElinzanetantClinical trial
A Double-Blind, Randomised, Placebo Controlled, Adaptive Design Study of the Efficacy, Safety and Pharmacokinetics of NT-814 in Female Subjects With Moderate to Severe Vasomotor Symptoms Associated With the MenopauseStatus: Completed, Estimated PCD: 2019-11-21
Clinical trial
A Randomized Double-blind Placebo Controlled Phase 3 Trial to Evaluate the Efficacy and Safety of Estetrol for the Treatment of Moderate to Severe Vasomotor Symptoms in Postmenopausal Women (E4Comfort Study I)Status: Active (not recruiting), Estimated PCD: 2024-02-01
Product
ProgesteroneClinical trial
Vaginal Progesterone Versus Placebo for the Treatment of Vaginal Atrophy - a Double Blind Randomized Control TrialStatus: , Estimated PCD: 2020-12-01
Product
Vaginal ProgesteroneClinical trial
Pharmacokinetic Aspects of 25-mg Estradiol Pellet in Climacteric Women Comprehensive Longitudinal Assessment of Release With Estradiol Pellet Analysis (CLARA Study)Status: Recruiting, Estimated PCD: 2024-10-30
Product
EstradiolClinical trial
Cardiometabolic Consequences of the Loss of Ovarian FunctionStatus: Not yet recruiting, Estimated PCD: 2028-05-31
Product
DegarelixProduct
Transdermal EstradiolProduct
Transdermal PlaceboClinical trial
The Impact of HIV on Accelerated Aging in the Female Genital Tract: a Pilot Trial of Topical Estradiol to Improve the Vaginal Microbiome and Symptoms of Vaginal Atrophy in Menopausal Women With HIVStatus: Completed, Estimated PCD: 2023-08-09
Clinical trial
Clinical Trial on the Treatment of Menopausal Syndrome With Chinese Medicine Gui-zhi-fu-ling-wan With Variation and the Mechanism of Anti-inflammation and Body Surface Temperature DistributionStatus: Not yet recruiting, Estimated PCD: 2025-10-31
Product
Guizhi FulingClinical trial
Study on the (Heart) Brain-gut Axis Mechanism of Qingxin Zishen Decoction in Treating Hot Flashes in Menopausal Syndrome Based on 16S rRNA Sequencing TechnologyStatus: Recruiting, Estimated PCD: 2024-08-31
Product
Qingxin Zishen decoctionProduct
FemostonClinical trial
The Effect of Valerian on Insomnia in Menopausal Women: Randomized Placebo-controlled TrialStatus: Recruiting, Estimated PCD: 2025-01-20
Product
ValerianClinical trial
Clinical Efficacy of Qingxin Zishen Decoction in Treating Menopausal Syndrome and Neuroendocrine Mechanism of Regulating KNDy NeuronsStatus: Completed, Estimated PCD: 2018-06-30
Product
Qingxin Zishen DecoctionClinical trial
Hot Flashes and Neurovascular Function in WomenStatus: Recruiting, Estimated PCD: 2025-12-01
Product
Sodium NitroprussideProduct
AcetylcholineProduct
TerbutalineProduct
NorepinephrineClinical trial
Effect of Local Estriol Treatment Before Vaginal Repair Surgery on Vaginal Tissues and Early Postoperative Pelvic Floor FunctionsStatus: Not yet recruiting, Estimated PCD: 2025-01-01
Product
EstriolClinical trial
Comparison Study of the Effectiveness Between Syndrome Differentiation Treatments and Fixed Formula Treatment for Perimenopausal Syndrome With Chinese Herbal MedicineStatus: Completed, Estimated PCD: 2023-06-30
Product
Intervention GroupProduct
Control GroupClinical trial
The Impact of Estrogen Status on the Biological Function of Brown Adipose Tissue in Women Measured Using Quantitative PET/CTStatus: Completed, Estimated PCD: 2023-05-02
Product
LeuprolideClinical trial
A Prospective Randomized Controlled Study of the Effects of Different Therapy Regimens on Menopausal Sleep DisordersStatus: Not yet recruiting, Estimated PCD: 2024-06-01
Product
TiboloneProduct
XiangshaoClinical trial
Estradiol Supplementation and Rotator Cuff Repair: A Preliminary Randomized TrialStatus: Not yet recruiting, Estimated PCD: 2028-03-01
Product
EstrogenClinical trial
Bioenergetic and Metabolic Consequences of the Loss of Ovarian Function in Women - 2018Status: Recruiting, Estimated PCD: 2024-08-31
Product
GnRH antagonistProduct
Placebo GnRH antagonistClinical trial
Ovarian Hormone Regulation of Central and Cerebrovascular HemodynamicsStatus: Active (not recruiting), Estimated PCD: 2024-09-30
Clinical trial
A Neurosteroid Intervention for Menopausal and Perimenopausal DepressionStatus: Recruiting, Estimated PCD: 2025-01-31
Product
PregnenoloneClinical trial
Menopausal Sleep Fragmentation: Impact on Body Fat Gain Biomarkers in WomenStatus: Completed, Estimated PCD: 2022-08-01
Clinical trial
The Impact of Anti-estrogenic Therapy in Breast Cancer Patients on Brain Architecture, Psychosexual Health, and Quality of LifeStatus: Not yet recruiting, Estimated PCD: 2025-12-01
Drug
TamoxifenProduct
LetrozoleProduct
Letrozole + GnRHClinical trial
Identifying Neurophysiological Mechanisms of Susceptibility to Estradiol Fluctuation and Irritability Symptoms in the Menopause Transition: An Experimental ApproachStatus: Recruiting, Estimated PCD: 2024-12-01
Product
Estradiol PatchDrug
VarlilumabClinical trial
Investigating Reactivation of Ovarian Function Following Autologous PRP Intra-ovarian Infusion in Menopausal WomenStatus: Recruiting, Estimated PCD: 2026-01-30
Product
Autologous PRPClinical trial
The Effect of Low-dose Rhythmic 17-β-estradiol Administration on Bone Turnover in Postmenopausal WomenStatus: Recruiting, Estimated PCD: 2024-07-01
Clinical trial
A Pilot Study to Evaluate the Anabolic Effect of Testosterone on Muscles of the Pelvic Floor in Older Women With Stress Urinary IncontinenceStatus: Not yet recruiting, Estimated PCD: 2026-07-01
Product
Testosterone cypionateClinical trial
Pharmacokinetic, Clinical, Hormonal and Therapeutic Effects of the Use of Estradiol and Testosterone Hormonal Subdermal Implants in Women With Natural Menopause, Premature Ovarian Failure or Surgical Menopause Due to Cervical Cancer.Status: Not yet recruiting, Estimated PCD: 2025-01-31
Product
Testosterone PelletProduct
Luo-Bu-Fu-Ke-Bi-RIProduct
tiboloneClinical trial
The Pilot Study of LINE-1 and Alu Methylation Levels Among Middle Aged Women With Low Cardiovascular Risk Profile in Respect of Menopausal Hot FlashesStatus: Active (not recruiting), Estimated PCD: 2022-12-01
Clinical trial
Evaluating Quality Performance of Extemporaneously Compounded Estrogen Hormone ProductsStatus: Recruiting, Estimated PCD: 2024-10-01
Product
EstrogelProduct
Compounded estradiolClinical trial
A Phase III Prospective, Randomized, Double-Blind Clinical Trial of Hormone Replacement Therapy In Postmenopausal Women With A History Of Node-Negative Or Ductal Carcinoma In Situ Who Are Receiving Adjuvant TamoxifenStatus: Completed, Estimated PCD: 2002-08-01
Product
Conjugated estrogensProduct
medroxyprogesteroneClinical trial
VABIP Study (Vaginal Biorevitalization With Polydeoxyribonucleotides) for the Improvement of the Genitourinary Syndrome of MenopauseStatus: Completed, Estimated PCD: 2021-11-23
Product
PolynucleotideProduct
Conjugated estrogens creamClinical trial
Role of Exogenous and Endogenous Sex Hormones on Tenofovir and EmtricitabineStatus: Completed, Estimated PCD: 2024-02-15
Product
TenofovirProduct
EmtricitabineClinical trial
PhytoSERM Efficacy to Prevent Menopause Associated Decline in Brain Metabolism and Cognition: A Double-Blind, Randomized, Placebo-Controlled Phase 2 Clinical TrialStatus: Recruiting, Estimated PCD: 2027-08-28
Clinical trial
Investigating Reactivation of Ovarian Function Following Autologous PRP Intra-ovarian Infusion in POI PatientsStatus: Recruiting, Estimated PCD: 2026-01-30
Product
Placebo-Platelet Free PlasmaClinical trial
Vitamin D Improves Osteoporosis in Postmenopausal Women With Denosumab FailureStatus: Completed, Estimated PCD: 2021-06-22
Drug
Vitamin D3Clinical trial
The Impact of Different Hormone Therapy Regimens on Overactive Bladder Symptoms, Sexual Function, Depressive Symptoms, Autonomic Function, and Arterial StiffnessStatus: Recruiting, Estimated PCD: 2023-12-31
Clinical trial
Treating Insomnia and Improving Glycemic Control in Midlife Women With Insomnia and Pre-diabetesStatus: Recruiting, Estimated PCD: 2024-09-30
Product
SuvorexantClinical trial
Safety of Oral Micronized Progesterone Versus Norethisterone Acetate in Continuous Combination With Oral Estrogen as Menopausal Hormone Therapy - a Double-blind Randomized Study- PROBES Study (Progesterone Breast Endometrial Safety Study)Status: Recruiting, Estimated PCD: 2026-09-01
Product
Micronized ProgesteroneProduct
Norethisterone acetateClinical trial
Effects of Novel Estrogens on Glucose and Lipids in Postmenopausal Prediabetic Women VeteransStatus: Withdrawn, Estimated PCD: 2024-04-08
Clinical trial
Impact of Early Aging and Menopause on the Vascular Responses to HypoxiaStatus: Not yet recruiting, Estimated PCD: 2025-07-01
Product
PropranololProduct
GemtesaClinical trial
Confirming Quality Performance of Extemporaneously Compounded Estrogen Hormone ProductsStatus: Recruiting, Estimated PCD: 2024-09-01
Product
Topical Estrogen