Organization
Chemistry, Bar Ilan University, Ramat Gan, Israel
3 abstracts
Abstract
AN ENPP1-SPECIFIC INHIBITOR ATTENUATES EXTRACELLULAR ECTO-PYROPHOSPHATASE ACTIVITY IN HUMAN OSTEOARTHRITIC CARTILAGE Org: Rheumatology, Tel Aviv Medical Center, Faculty of Medicine, Tel Aviv University, Tel Aviv, Chemistry, Bar Ilan University, Ramat Gan, Israel,
Abstract
ARRY-162, A SELECTIVE, POTENT MEK1/2 INHIBITOR, SIGNIFICANTLY REDUCES EX VIVO IL-1 BETA AND TNF ALPHA; PRODUCTION IN NORMAL SUBJECTSOrg: Chemistry, Bar Ilan University, Ramat Gan, Israel, Biology Department, Bashkir State Medical University, Pharmacology Discovery Services Taiwan, Ltd., Translational Research Institute and Dermatology Institute, Drug Metabolism,
Abstract
ARRY-797, A SELECTIVE, POTENT INHIBITOR OF P38, PROMOTES DISEASE NORMALIZATION IN ANIMAL MODELS OF RHEUMATOID ARTHRITIS AND SIGNIFICANTLY REDUCES EX VIVO IL-1 BETA, PGE2 AND TNF- ALPHA PRODUCTION IN NORMAL HUMAN SUBJECTSOrg: Pharmacology Discovery Services Taiwan, Ltd., Biology Department, Bashkir State Medical University, Clinical Trials Unit, Institute of Precision Medicine, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Chemistry, Bar Ilan University, Ramat Gan, Israel, Drug Metabolism,