Organization
Qilu Hospital of Shandong University
30 clinical trials
28 abstracts
Abstract
Perioperative toripalimab + platinum-doublet chemotherapy vs chemotherapy in resectable stage II/III non-small cell lung cancer (NSCLC): Interim event-free survival (EFS) analysis of the phase III NEOTORCH study.Org: Shanghai Chest Hospital, Hunan Cancer Hospital, Department of Pulmonary Medicine, Department of Thoracic Surgery and Oncology, Cancer Hospital of the University of Chinese Academy of Sciences,
Abstract
Efficacy of disitamab vedotin (RC48) plus tislelizumab and S-1 as first-line therapy for HER2-overexpressing advanced stomach or gastroesophageal junction adenocarcinoma: A multicenter, single-arm, phase II trial (RCTS).Org: Qilu Hospital of Shandong University, The Affiliated Hospital of Qingdao University, The Third Hospital of Shandong Province, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Yantai Yuhuangding Hospital,
Abstract
Distribution and mutational landscape of inherited cancer susceptibility syndromes in central nervous system tumors.Org: Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd.,
Abstract
Updated safety and efficacy data of combined KRAS G12C inhibitor (glecirasib, JAB-21822) and SHP2 inhibitor (JAB-3312) in patients with KRAS p.G12C mutated solid tumors.Org: Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Peking University Cancer Hospital and Institute, Beijing, China, Second Department of Thoracic Tumors, Peking University Cancer Hospital, Department of Medical Oncology, Harbin Medical University Cancer Hospital, Tongji Hospital, Tongji Medical College Huazhong University of Science and Technology,
Clinical trial
A Real-world Study of Octreotide Microspheres in Chinese Patients With Neuroendocrine TumorsStatus: Not yet recruiting, Estimated PCD: 2027-11-26
Clinical trial
REACH-01:A Single-arm, Prospective Study of HAIC Sequential TAE Combined With Tislelizumab and Surufatinib in Unresectable Intrahepatic CholangiocarcinomaStatus: Recruiting, Estimated PCD: 2024-05-31
Abstract
A comparative study of double track anastomosis and tubular esophagogastric anastomosis in laparoscopic radical proximal gastrectomy for upper gastric carcinoma.Org: Qilu Hospital of Shandong University,
Abstract
Effect of simvastatin on PD-L1 via ILF3 to enhance CD8+ T cell-mediated ferroptosis in gastric cancer cells.Org: Qilu Hospital of Shandong University, Shandong University of Traditional Chinese Medicine Affiliated Hospital,
Abstract
Phase I summary of the HB0025 efficacy and safety to the heavily pretreated non-small cell lung cancer (NSCLC) population.Org: Fudan University Shanghai Cancer Center, Phase I Cinical Trial Center, Central Hospital Affiliated to Shandong First Medical University, Jinan, China, Jinan Central Hospital, Shandong University, Shandong University of Traditional Chinese Medicine Affiliated Hospital,
Abstract
The patient outcomes with EGFR-mutated advanced non-small-cell lung cancer receiving aumolertinib as first-line treatment.Org: Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy, Italy, Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University of Traditional Chinese Medicine Affiliated Hospital, School of Pharmaceutical Sciences,
Abstract
Effect of first-line bevacizumab on prognosis of second or later-line immunotherapy in patients with advanced non-squamous non-small cell lung cancer: A retrospective analysis.Org: Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan YZY Biopharma, Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy, Italy, Qilu Hospital of Shandong University, Jinan,
Abstract
Development and validation of a prediction model for lymph node metastasis based on molecular classification in endometrial carcinoma.Org: Shandong University of Traditional Chinese Medicine Affiliated Hospital, Qilu Hospital of Shandong University, Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Beijing, China,
Abstract
Differences in clinical features between CA-125 and RECIST progression in patients with ovarian cancer treated with PARP inhibitors.Org: Qilu Hospital of Shandong University, Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, China, Qilu Hospital of Shandong University, Shandong, China, Qilu Hospital of Shandong University, Jinan, China,
Clinical trial
Irinotecan in Combination With Trifluridine-tipiracil and Bevacizumab in Pre-treated Metastatic Colorectal CancerStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
Clinical Observation on the Prognosis of Long-term Cardiac Function by Drug Withdrawal in Patients With Peripartum Cardiomyopathy With Cardiac Function RecoveryStatus: Not yet recruiting, Estimated PCD: 2023-10-10
Clinical trial
Eltrombopag Plus Diacerein vs Eltrombopag in Adult Primary Immune Thrombocytopenia: a Multicenter Randomized Controlled TrialStatus: Completed, Estimated PCD: 2021-12-01
Clinical trial
A Real-world Study of Surufatinib in Refractory Metastatic G3 Neuroendocrine TumorsStatus: Not yet recruiting, Estimated PCD: 2024-06-01
Clinical trial
The Clinical Efficacy and the Changes of Immune Cells Subsets With Bioagents in Ankylosing Spondylitis PatientsStatus: Active (not recruiting), Estimated PCD: 2024-12-31
Clinical trial
Efficacy and Safety of Serplulimab, Lenvatinib, and Paclitaxel in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma After First-line Immunotherapy: a Prospective, Single-armed Clinical TrialStatus: Recruiting, Estimated PCD: 2024-11-01
Clinical trial
Efficacy and Safety of Bismuth Quadruple Therapy Containing Cefuroxime and Tetracycline as First-line Therapy for Eradicating Helicobacter Pylori in Patients Allergic to Penicillin: A Multicenter, Randomized Controlled StudyStatus: Not yet recruiting, Estimated PCD: 2024-12-01
Clinical trial
A Retrospective Observational Study on the Effects of Probiotics on HBsAg ClearanceStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
Randomized, Double-blind, Controlled Study of Clomastine Fumarate in the Treatment of Williams SyndromeStatus: Recruiting, Estimated PCD: 2025-03-02
Clinical trial
The Efficacy and Safety of Fluzopril Combined With Apatinib in Maintenance Treatment of Platinum Resistant Recurrent Ovarian Cancer PatientsStatus: Not yet recruiting, Estimated PCD: 2025-11-01
Clinical trial
Circulating Tumor DNA Minimal Residual Disease-guided Adjuvant Chemotherapy in Patients With Stage II-III Gastric CancerStatus: Recruiting, Estimated PCD: 2027-04-01
Clinical trial
Microvascular Angina Intervention With Compound Danshen Dripping Pill (MAIDS)Status: Recruiting, Estimated PCD: 2027-06-30
Clinical trial
Doublet or Triplet Chemotherapy With Cetuximab as Conversion Therapy in RAS/BRAF Wild Type Unresectable Liver Metastasis Right-sided Colon Cancer With Curative Intent:Multi-center, Ambispective Observational TrialStatus: Recruiting, Estimated PCD: 2024-12-30
Clinical trial
The Correlation of Reduction of Levodopa and Non-motor Symptoms of Parkinson's Disease After Deep Brain StimulationStatus: Completed, Estimated PCD: 2022-06-01
Clinical trial
Regulation of Cardiac Function After TAVR in Patients With Severe Aortic Stenosis Combined With Cardiac Insufficiency: a Prospective, Single-center, Randomized Controlled StudyStatus: Recruiting, Estimated PCD: 2025-01-01
Clinical trial
Efficacy and Safety of Tofacitinib (TF) Combined With Iguratimod(IGU) in the Treatment of Moderate to Severe Active Rheumatoid Arthritis (RA)Status: Completed, Estimated PCD: 2023-06-30
Clinical trial
Treatment and Clinical Outcomes Among SLE Patients in Pregnancy: A Real World StudyStatus: Recruiting, Estimated PCD: 2025-07-30
Clinical trial
Efficacy and Safety of Pseudomonas Aeruginosa Followed by Postoperative Intravesical Instillation in Patients With Intermediate and High-risk Non-muscle Invasive Bladder Cancer: a Multi-center, Single-arm Clinical StudyStatus: Recruiting, Estimated PCD: 2025-08-01
Clinical trial
Effects of Continuous Lidocaine Infusion Via Closed Chest Drainage Tube on Postoperative Analgesia for Patients Undergoing Thoracoscopic Partial Lung Resection: a Single-center Randomized Controlled Clinical TrialStatus: Not yet recruiting, Estimated PCD: 2023-06-01
Clinical trial
The Efficacy and Safety of Bevacizumab in Patients With Severe Covid-19: a Multicenter, Randomized, Double-blind, Parallel-group, Placebo-controlled TrialStatus: Recruiting, Estimated PCD: 2023-11-30
Clinical trial
The Effects of Intravenous Fosaprepitant and Ondansetron for the Prevention of Postoperative Nausea and Vomiting in Thoracicsurgery Patients: A Single-center, Randomized, Double-Blinded Clinical StudyStatus: Not yet recruiting, Estimated PCD: 2023-06-01
Clinical trial
Combination of Disitamab Vedotin and Anlotinib in the Treatment of HR-Negative, HER2-Low-Expressing Metastatic Breast Cancer: A Single-Arm, Multicenter, Phase II Clinical StudyStatus: Not yet recruiting, Estimated PCD: 2024-12-31
Clinical trial
Efficacy and Safety of Apantamide Combined With Docetaxel and ADT vs. Apantamide Combined With ADT in Patients With High Tumor Burden mHSPC: a Multicenter and Prospective Cohort StudyStatus: Recruiting, Estimated PCD: 2026-02-01
Clinical trial
Prospective Clinical Study to Observe the Efficacy and Safety of Iguratimod in Rheumatoid Arthritis and Early Rheumatoid Arthritis Patients for 6 Months Treatment in ChinaStatus: Completed, Estimated PCD: 2023-09-30
Clinical trial
Efficacy, Safety and Predictive Indicators of Immunosuppressant Combined With Pirfenidone in the Treatment of Connective Tissue Disease-related Interstitial Lung Disease (CTD-ILD)Status: Active (not recruiting), Estimated PCD: 2024-06-01
Clinical trial
Development and Validation of Logistic Regression Models to Predict Durable Functional Cure in Patients With Chronic Hepatitis B After Pegylated Interferon Alpha-2b Based TherapyStatus: Recruiting, Estimated PCD: 2024-07-31
Clinical trial
The Clinical Features and Pregnancy Outcomes of Patients With Connective Tissue Disease :a Prospective Cohort StudyStatus: Recruiting, Estimated PCD: 2025-06-30
Abstract
Neoadjuvant camrelizumab plus chemotherapy for locally advanced cervical cancer (NACI study): A prospective, single-arm, phase II trial.Org: Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China, Tongji Medical College Huazhong University of Science and Technology, Huazhong University of Science and Technology Union Shenzhen Hospital, Wuhan, China, Women's Hospital School of Medicine Zhejiang University,
Abstract
A phase II/III study of camrelizumab plus apatinib as perioperative treatment of resectable hepatocellular carcinoma at intermediate-high risk of recurrence: Primary results of major pathologic response from phase II stage.Org: Liver Cancer Institute and Zhongshan Hospital, Fudan University, Shanghai, China, Zhongshan Hospital of Fudan University, Shanghai, China, Key Laboratory of Carcinogenesis and Cancer Invasion (Ministry of Education), Fudan University, Third Affiliated Hospital of Naval Medical University (Eastern Hepatobiliary Surgery Hospital), Qilu Hospital of Shandong University,
Abstract
Safety and efficacy of HB0025, an anti-PD-1/VEGF bispecific antibody fusion protein, in patients with advanced solid tumors: Preliminary results from an FIH trial.Org: Phase I Clinical Trial Center, Fudan University Shanghai Cancer Center, Shanghai, China, Fudan University Shanghai Cancer Center, Central Hospital Affiliated to Shandong First Medical University, Jinan, China, Next Oncology Virginia and Virginia Cancer Specialists, Linyi Cancer Hospital,
Abstract
Pegylated liposomal doxorubicin and carboplatin versus paclitaxel and carboplatin as first-line treatment for Chinese patients with ovarian cancer: A multi‑center, randomized, open‑label trial.Org: Women's Hospital School of Medicine Zhejiang University, Qilu Hospital of Shandong University, The First Affiliated Hospital of USTC, Anhui Provincial Hospital, Hefei, China, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China, West China Second University Hospital,
Abstract
Diagnostic model of low-grade serous ovarian cancer and borderline serous ovarian tumor: Model development and validation based on radiomics.Org: Qilu Hospital of Shandong University, Shandong University of Traditional Chinese Medicine Affiliated Hospital,
Abstract
Analysis of short-term efficacy and safety of mitoxantrone hydrochloride liposome regimen therapy in adult acute myeloid leukemia.Org: Department of Hematology & Oncology, College of Medicine, University of Oklahoma Health Sciences Center, Harbin Institute of Hematology & Oncology, Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, China, Tangdu Hospital, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, Winship Cancer Institute of Emory University, Atlanta, GA, Emory University, Atlanta, GA, Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, Department of Medicine, Massachusetts General Hospital, Boston, MA, Department of Medicine, Emory University School of Medicine, Atlanta, GA, Department of Urology, Emory University School of Medicine, Atlanta, GA,
Abstract
The impact of lymphadenectomy on survival outcomes of ovarian clear cell carcinoma: A systematic review and meta-analysis.Org: Qilu Hospital of Shandong University, Jinan, China,
Abstract
A web-based prediction model for overall survival of elderly patients with epithelial ovarian cancer: A population-based study.Org: Qilu Hospital of Shandong University, Jinan, China,
Abstract
Efficacy and safety of regorafenib plus biweekly TAS-102 for refractory metastatic colorectal cancer (REGTAS): A multicenter single-arm phase II trial.Org: Qilu Hospital of Shandong University, Jinan, China National Biotec Group, Linyi Cancer Hospital, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China,
Abstract
Prognostic risk stratification of low-grade serous ovarian cancer: Model development and validation based on machine learning algorithm.Org: Qilu Hospital of Shandong University, Jinan, China,
Abstract
TQB2450 plus anlotinib combined with paclitaxel and cisplatin as first-line treatment of advanced esophageal squamous cell carcinoma (ESCC): Update results of a single-arm, multicenter phase Ⅱ trial.Org: Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy, Italy, Anyang Cancer Hospital, Anyang, China, Henan Cancer Hospital, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China, The First Affiliated Hospital of Henan University of Science and Technology,
Abstract
Study of endometrial carcinoma on correlation between molecular typing and lymph node metastasis and construction of prediction model.Org: Qilu Hospital of Shandong University, Jinan, China,
Abstract
Oxaliplatin based chemotherapy for advanced well-differentiated neuroendocrine tumors: A systematic review and meta-analysis.Org: Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy, Italy, Qilu Hospital of Shandong University, Jinan, China National Biotec Group,
Abstract
Development and validation of prediction models for coexisting adnexa malignancy in patients with endometrial cancer using machine learning algorithm: A population-based cohort study.Org: Qilu Hospital of Shandong University, Jinan, China,
Abstract
A novel prognostic model for high-grade endometrial cancer using combined neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR).Org: Qilu Hospital of Shandong University, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China, Tongji Medical College Huazhong University of Science and Technology, Huazhong University of Science and Technology Union Shenzhen Hospital, Women's Hospital,
Abstract
Circulating tumor DNA (ctDNA) methylation-based linkage regions to predict recurrence in early-stage lung cancer.Org: Qilu Hospital of Shandong University, ChosenMed Technology (Zhejiang) Co., Ltd., The Affiliated Hospital of Qingdao University, Shengli Oilfield Central Hospital, Zibo Central Hospital,
Clinical trial
An Open-Label, Single Arm Study to Evaluate the Efficacy and Safety of Adebrelimab Plus Apatinib as Adjuvant Therapy in Participants With Hepatocellular Carcinoma at High Risk of Recurrence After Surgical ResectionStatus: Recruiting, Estimated PCD: 2026-12-01
Abstract
A NOVEL DRUG COMBINATION OF IGURATIMOD AND TOFACITINIB ALLEVIATES RHEUMATOID ARTHRITIS AND SECONDARY OSTEOPOROSISOrg: Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Shandong Provincial Clinical Research Center for Immune Diseases and Gout, Department of Rheumatology, Jinan, China, School and Hospital of Stomatology,