Organization
Nationwide Children's Hospital
28 clinical trials
3 abstracts
Abstract
Preliminary experience of ex-vivo expanded allogeneic universal donor TGFβi NK cell infusions in combination with irinotecan, temozolomide, and dinutuximab in patients with relapsed or refractory neuroblastoma: The Allo - STING trial.Org: Nationwide Children's Hosp, Columbus, OH, OHB Neonatology, Nationwide Childrens Hospital, Nationwide Children's Hospital,
Clinical trial
A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft TissueStatus: Recruiting, Estimated PCD: 2026-12-01
Clinical trial
A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade GliomaStatus: Active (not recruiting), Estimated PCD: 2024-08-01
Clinical trial
Phase 2 Trial of a Novel Peptide Vaccine (PEP-CMV) Targeting CMV Antigen for Newly Diagnosed Pediatric High-grade Glioma and Diffuse Intrinsic Pontine Glioma and Recurrent MedulloblastomaStatus: Not yet recruiting, Estimated PCD: 2028-06-15
Abstract
Comparison of immunoglobulin high-throughput sequencing MRD in bone marrow and peripheral blood in pediatric B-ALL: A report from the Children's Oncology Group AALL1731.Org: Adaptive Biotechnologies, Baylor College of Medicine, Servier Pharmaceuticals, Perlmutter Cancer Center, New York University Langone Health, University of Washington School of Medicine,
Clinical trial
A Phase I/II Safety Lead in Study of Ex-Vivo Expanded Allogeneic Universal Donor TGFβi NK Cell Infusions in Combination With Irinotecan, Temozolomide, and Dinutuximab in Patients With Relapsed or Refractory Neuroblastoma: The Allo - STING TrialStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight InfantsStatus: Recruiting, Estimated PCD: 2026-02-28
Clinical trial
Effect of Vitamin D Supplementation on Rate of Partial Clinical Remission in Children and Adolescents With Type 1 DiabetesStatus: Completed, Estimated PCD: 2014-06-01
Clinical trial
Phase I/IIa Trial Evaluating scAAV1.tMCK.NTF3 for Treatment of Charcot-Marie-Tooth Neuropathy Type 1A (CMT1A)Status: , Estimated PCD: 2028-04-01
Clinical trial
Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA® (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous CraniopharyngiomaStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
PhaseII Study of Ribociclib and Everolimus Following Radiotherapy in Pediatric and Young Adult Patients Newly Diagnosed With HGG Including DIPG, Which Harbor Alterations of the Cell Cycle and/or PI3K/mTOR PathwaysStatus: Not yet recruiting, Estimated PCD: 2028-05-30
Clinical trial
A Pilot and Surgical Study of Larotrectinib for Treatment of Children With Newly-Diagnosed High-Grade Glioma With NTRK FusionStatus: Recruiting, Estimated PCD: 2025-12-01
Clinical trial
Phase I Clinical Intramuscular Gene Transfer of rAAV1.CMV.huFollistatin344 Trial to Patients With Becker Muscular Dystrophy and Sporadic Inclusion Body Myositis.Status: Completed, Estimated PCD: 2017-10-01
Clinical trial
A Randomized Controlled Pilot Trial of Baclofen for Children With Rumination SyndromeStatus: Recruiting, Estimated PCD: 2023-12-01
Clinical trial
Safety and Feasibility of On-Site Manufacture of CD19 CAR T Cells Using the CliniMACS Prodigy in Pediatric and Young Adult Patients With Relapsed/Refractory CD19 Positive Acute Lymphoblastic Leukemia and Non-Hodgkin's LymphomaStatus: Not yet recruiting, Estimated PCD: 2026-12-01
Clinical trial
Characterization of Clinical Skeletal and Cardiac Impairment in Carriers of Duchenne Muscular Dystrophy (DMD) and Becker Muscular Dystrophy (BMD)Status: Recruiting, Estimated PCD: 2025-12-01
Clinical trial
Assessment of Regional Anesthetic Blockade Using Non-Invasive Surface Electromyogram (EMG)Status: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
Open-Label Pilot Study of Haploidentical Donor Adenovirus Specific T Lymphocytes (ADV-VSTS) for the Treatment of Refractory Adenovirus Infection and/or Disease in Hospitalized PatientsStatus: Recruiting, Estimated PCD: 2024-10-01
Clinical trial
Phase 2 Study of Cabozantinib as a Maintenance Agent to Prevent Progression or Recurrence in High-Risk Pediatric Solid TumorsStatus: Recruiting, Estimated PCD: 2025-12-01
Clinical trial
A Phase II Study of <131>I-Metaiodobenzyguanidine (<131>I-MIBG) Therapy for Patients With MIBG Avid TumorsStatus: Active (not recruiting), Estimated PCD: 2025-03-01
Clinical trial
Phase I Study of Intra-Tumoral Injections of Autologous Ex Vivo Expanded Natural Killer Cells in Children With Recurrent High Grade GliomaStatus: Not yet recruiting, Estimated PCD: 2024-10-01
Clinical trial
GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODSStatus: Recruiting, Estimated PCD: 2027-05-31
Clinical trial
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS (TRIPS)Status: Recruiting, Estimated PCD: 2027-05-15
Clinical trial
Prospective, Open-labeled, Single-arm Clinical Trial to Evaluate the Safety and Efficacy of the Second-generation Tissue Engineered Vascular Graft as Vascular Conduits for Extracardiac Total Cavopulmonary Connection.Status: Recruiting, Estimated PCD: 2025-08-01
Clinical trial
Phase 2 Study of the MEK Inhibitor MEKTOVI® (Binimetinib) for the Treatment of Pediatric Adamantinomatous CraniopharyngiomaStatus: Recruiting, Estimated PCD: 2025-04-10
Clinical trial
A Pilot Study of Lorlatinib for Treatment of Children With Newly Diagnosed High-Grade Glioma With ROS-1 (ROS Proto-Oncogene 1, Receptor Tyrosine Kinase) or ALK (Anaplastic Lymphoma Kinase) FusionStatus: Not yet recruiting, Estimated PCD: 2027-09-01
Clinical trial
Killer Cells Against Relapsed/Refractory Myeloid Acute Leukemia (KARMA): A Clinical Trial Evaluating the Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Treatment of Young Adults With Relapsed/Refractory Acute Myeloid LeukemiaStatus: Recruiting, Estimated PCD: 2027-02-01
Clinical trial
Pathophysiological Evidence Driven Management of GERD in Neonatal ICU Infants: Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2027-11-01
Abstract
Subsequent meningiomas in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study (CCSS).Org: Dana-Farber/Boston Children's Cancer and Blood Disorders Center, University of Alberta, University of Minnesota Masonic Cancer Center, Minneapolis, MN, Fred Hutchinson Cancer Research Center, MD Anderson Cancer Center,
Clinical trial
Safety and Feasibility of On-Site Manufacture of CD19 CAR T Cells Using the CliniMACS Prodigy in Pediatric and Young Adult Patients With Relapsed/Refractory CD19 Positive Acute Lymphoblastic Leukemia and Non-Hodgkin's LymphomaStatus: Not yet recruiting, Estimated PCD: 2026-12-01