Organization
Department of Surgery, Brigham and Women's Hospital, Boston, MA
59 abstracts
Abstract
Neoadjuvant immune-checkpoint blockade therapy combined with TACE for resectable hepatocellular carcinoma with high recurrence risk: A phase II, single-arm clinical trial (MORNING).Org: Center of Hepato-Pancreato-Biliary Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Department of Interventional Oncology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Department of Interventional Radiology, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Clinical Trials Unit, Institute of Precision Medicine, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China,
Abstract
Neoadjuvant therapy in patients with pancreatic ductal adenocarcinoma (PDAC) with germline DNA damage repair (DDR) mutations: A dual institution retrospective study.Org: Cedars-Sinai Medical Center, Samuel Oschin Comprehensive Cancer Institute, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA,
Abstract
Genomic and transcriptomic biomarkers of nab-paclitaxel plus gemcitabine-cisplatin in patients with advanced biliary tract cancer.Org: Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milano), Italy, CHA University School of Medicine, Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy, Italy, CHA Bundang Medical Center, Department of Surgery, Brigham and Women's Hospital, Boston, MA,
Abstract
Detection of contralateral breast cancer in patients with primary breast cancer through AI-assisted mammography.Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea,
Abstract
Correlation of ctDNA with hematologic ratios (NLR, MLR, PLR, ELR) in predicting disease progression in soft tissue sarcomas among non-Hispanic Whites and Hispanics: Single-center experience.Org: Creighton University School of Medicine Phoenix Regional Campus, Creighton University Medical Center, Mayo Clinic, Dignity Health Cancer Institute, Dignity Health Cancer Center,
Abstract
Real-world treatment practices in patients with muscle invasive bladder cancer (MIBC) treated in Alberta, Canada.Org: University of Calgary, Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan, Princess Margaret Cancer Center, University Health Network, University of British Columbia,
Abstract
Disparities in diagnosis and access to care in patients with young-onset rectal cancers in northeast Ohio.Org: Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China, University Hospitals Seidman Cancer Center, Case Western Reserve University School of Medicine, Department of Surgery, Brigham and Women's Hospital, Boston, MA, University Hospitals Cleveland Medical Center,
Abstract
Sustained organ preservation in rectal cancer patients treated with total neoadjuvant therapy: Long-term results of the OPRA trial.Org: Memorial Sloan Kettering Cancer Center, Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, Colorectal Service, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China,
Abstract
Correlation of CDKN2A genomic alterations with tumor response to palbociclib given before chemoradiation therapy (CRT) to patients with human papillomavirus (HPV)-negative, locally advanced head and neck squamous-cell carcinoma (LA-HNSCC): A single-arm, phase 2 trial.Org: Washington University School of Medicine in St Louis, Washington University in Saint Louis Department of Biomedical Engineering, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Washington University Siteman Cancer Center, St. Louis, MO, Washington University in St. Louis,
Abstract
Impact of surgical weight loss treatments on care burden among obese endometrial cancer survivors.Org: University at Buffalo School of Public Health and Health Professions, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Jacobs School of Medicine and Biomedical Sciences, Roswell Park Cancer Institute,
Abstract
Efficacy of adjuvant therapy in patients (pts) with AJCC v8 stage IIIA cutaneous melanoma.Org: Melanoma Institute Australia, The Netherlands Cancer Institute, Amsterdam University Medical Centers, The University of Texas MD Anderson Cancer Center, Stem Cell Transplantation Rsch, Houston, TX, The Christie NHS Foundation Trust,
Abstract
Evolving adjuvant estrogen therapy prescribing among breast oncology workforce.Org: University of Chicago, University of Chicago Medical Center, Chicago, IL, Section of Urology, Department of Surgery, Brigham and Women's Hospital, Boston, MA, University of Chicago Department of Urology,
Abstract
Impact of neoadjuvant chemo-immunotherapy on surgical outcomes and time to radiation in triple negative breast cancer.Org: Breast Service, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Memorial Sloan Kettering Cancer Center, New York, NY, Biostatistics Service,
Abstract
Circulating tumor DNA dynamics as an early predictor of recurrence in patients with radically resected colorectal cancer: Updated results from GALAXY study in the CIRCULATE-Japan.Org: National Cancer Center Hospital East, Kashiwa, Japan, Cancer Chemotherapy Center, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan, Natera, Inc.,
Abstract
Nationwide implementation of best practices in pancreatic cancer care (PACAP-1): Stepped-wedge cluster randomized trial.Org: Amsterdam UMC, VU University Medical Center, Amsterdam, Netherlands, University of Amsterdam, Netherlands Comprehensive Cancer Organisation (IKNL), Department of Surgery, Brigham and Women's Hospital, Boston, MA, Department of Gastroenterology and Hepatology, Hokkaido University Hospital, Hokkaido, Japan,
Abstract
T cell receptor-engineered T cells targeting a human endogenous retrovirus in kidney cancer.Org: Laboratory of Transplantation Immunotherapy, Cellular and Molecular Therapeutics Branch, NHLBI, NIH, Department of Surgery, Brigham and Women's Hospital, Boston, MA, T-Cure Bioscience, Center for Cellular Engineering,
Abstract
Pathologic complete response after neoadjuvant systemic therapy for breast cancer in BRCA mutation carriers and noncarriers.Org: Breast Service, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Memorial Sloan Kettering Cancer Center, New York, NY, Biostatistics Service,
Abstract
Multi-institutional study evaluating the role of circulating tumor DNA (ctDNA) in management of appendiceal cancers (AC).Org: University of Chicago Medical Center, Chicago, IL, Chicago, IL, Il-Yang Pharmaceuticals, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Section of Surgical Oncology,
Abstract
Whole-genome sequencing based assessment of HER2 focal amplification for precision oncology of breast cancers.Org: Genome Insight Inc., Samsung Medical Center, Division of Breast Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Research Institute for Future Medicine,
Abstract
A powerful drug combination strategy targeting BRAF-mutant melanoma.Org: University Hospitals Sussex NHS Foundation Trust, Seidman Cancer Center, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center,
Abstract
The significance of mucin on rectal MRI in patients with locally advanced rectal cancer being considered for watch-and-wait after neoadjuvant therapy.Org: Memorial Sloan Kettering Cancer Center, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, Department of Surgery, Brigham and Women's Hospital, Boston, MA,
Abstract
Safety and efficacy of PIPAC in ovarian cancer patients with peritoneal metastases: A first-in-US phase I study.Org: City of Hope National Medical Center, City of Hope Medical Group, City of Hope Cancer Center, City of Hope Comprehensive Cancer Center, City of Hope National Comprehensive Cancer Center,
Abstract
Survival after isolated hepatic perfusion as a treatment for uveal melanoma liver metastases: Results from a randomized controlled trial (the SCANDIUM trial).Org: Gothenburg University, Department of Oncology and Haematology, Division of Oncology, University Hospital of Modena, Modena, Italy, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital,
Abstract
Additional prognostic value of the BCT score in patients with ER+HER2- breast cancer receiving 21-gene assay–guided adjuvant treatments.Org: Gangnam Severance Hospital, Yonesi University College of Medicine, Seoul National University Hospital, Asan Medical Center, Center for Breast Cancer,
Abstract
The number of lymph nodes examined as a poor prognosis factor in stage II and stage III colon cancer patients undergoing curative surgery.Org: Yonsei University College of Medicine, Netherlands Comprehensive Cancer Organisation (IKNL), Yonsei Cancer Center, Yonsei University Health System, Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, SongDang Institute for Cancer Research, Yonsei University College of Medicine, Seoul, South Korea, Department of Internal Medicine C, University Hospital Greifswald, Greifswald, Germany,
Abstract
Preliminary results of sequential transarterial chemoembolization and stereotactic body radiotherapy followed by immunotherapy using single tremelimumab regular interval durvalumab in locally advanced, unresectable hepatocellular carcinoma (START-FIT using STRIDE): A single-arm, phase II study.Org: The University of Hong Kong, The Chinese University of Hong Kong, Department of Clinical Oncology, The Affiliated Cancer Hospital of Nanjing Medical University, Tuen Mun Hospital, University of Hong Kong,
Abstract
CRES3T: A single-arm confirmatory trial of S-1 plus cisplatin with concurrent radical-dose radiotherapy followed by surgery for superior sulcus tumor.Org: Juntendo University School of Medicine, Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan, Hiroshima University, National Cancer Center Hospital Japan East, Kashiwa, Japan, Division of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX,
Abstract
Infrastructure for rare cancer in the Netherlands: Towards a comprehensive platform for early detection and diagnosis of rare cancers (FORCE).Org: The Netherlands Cancer Institute, Amsterdam/UMC Utrecht ENETS Centre of Excellence, Department of Endocrine Oncology, University Medical Center Groningen, Máxima Medical Center,
Abstract
Omission of breast surgery for predicted pCR patients with MRI and vacuum-assisted biopsy in breast cancer after neoadjuvant chemotherapy: A multicenter, single-arm, non-inferiority trial (OPTIMIST trial).Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, Seoul National University College of Medicine, Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Seoul National University Hospital, Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy,
Abstract
Prospective single-arm study of endocrine therapies with ovarian function suppression in premenopausal patients with node-positive early breast cancer with low genomic risk (INTERSTELLAR trial, KBCSG-25).Org: Gangnam Severance Hospital, Yonesi University College of Medicine, Gangnam-Gu, Nacuity Pharmaceuticals, Korea United Pharmaceuticals Inc.,
Abstract
Positive margin and advanced depth of invasion as the indicators for assessing the necessity of adjuvant chemoradiotherapy in early-stage oral cavity squamous cell carcinoma.Org: Division of Hematology and Oncology, Department of Internal Medicine, China Medical University Hospital, Taichung, Taiwan, Department of Internal Medicine C, University Hospital Greifswald, Greifswald, Germany, Chung Shan Medical University Hospital, Department of Dentistry, Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China,
Abstract
Impact of distance between tumor and nipple on survival outcomes in breast cancer.Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, Seoul Metropolitan Government Seoul National University, Boramae Medical Center, Seoul, South Korea, Seoul National University College of Medicine,
Abstract
The mutational landscape of Chinese breast cancer by liquid biopsy.Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, Xijing Hospital of the Fourth Military Medical University, HaploX Biotechnology, Shenzhen, China,
Abstract
Risk stratification tools to help decide on adjuvant chemotherapy usage in resected soft tissue sarcomas: A 10 year review of an Irish sarcoma centre experience.Org: Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy, Italy, Cork University Hospital Group, Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China, Pathology Department, Cancer Research@UCC,
Abstract
Trabectedin failure-free survival (TFFS) after resuming trabectedin (T) in advanced myxoid liposarcoma (MLPS) patients.Org: Italian National Cancer Institute, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy, Adult Mesenchymal Tumour & Rare Cancer Medical Oncology Unit, Sarcoma Service, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, Department of Surgery, Brigham and Women's Hospital, Boston, MA,
Abstract
Preoperative pembrolizumab for MSI high, EBV positive or PD-L1 positive locally advanced gastric cancer followed by surgery and adjuvant chemoradiation with pembrolizumab: Interim results of a phase 2 multi-center trial.Org: Rutgers Cancer Institue of New Jersey, Winship Cancer Institute, Emory University School of Medicine, Division of Surgical Oncology, Department of Surgery, The Ohio State University, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Emory University, Atlanta, GA, USA,
Abstract
Breast cancer staging for patients with “low risk” disease: Are they all the same?Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, Duke University Medical Center, Department of Biostatistics and Bioinformatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Duke Cancer Institute,
Abstract
Total pancreatectomy: Experience within an integrated health care system.Org: University of California, Davis, UCSF East Bay, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Kaiser Permanente Northern California,
Abstract
A phase I, randomized, controlled, multicentre trial of isolated hepatic perfusion in combination with ipilimumab and nivolumab in patients with uveal melanoma metastases (the SCANDIUM 2 trial).Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, University of Gothenburg, Gothenburg, Sweden,
Abstract
Sustained prognostic impact of primary tumor characteristics on long-term (overall) survival after distant metastasis in young ER+ HER2- breast cancer.Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, Dongtan Sacred Heart Hospital, Hallym University, Seoul National University College of Medicine, Samsung Medical Center,
Abstract
Incidence of synchronous and metachronous peritoneal metastases for gallblader cancer: A single-center cohort analysis.Org: Charité - Universitätsmedizin Berlin, Berlin, Germany, Chirurgische Klinik, Campus Virchow Klinikum, Charité– Universitaetsmedizin Berlin, Corporate Member of Freie Universitaet Berlin and Humboldt-Universitaet Zu Berlin,
Abstract
Cost-effectiveness analysis of a circulating tumor DNA-based molecular residual disease assay to guide adjuvant chemotherapy decisions in patients with resectable early stage colorectal cancer.Org: Avalon Health Economics, Schulich School of Medicine and Dentistry, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Department of Internal Medicine C, University Hospital Greifswald, Greifswald, Germany,
Abstract
The prognostic value of degree of pre- and post-treatment anemia in patients with advanced gastroesophageal cancers.Org: University of Toronto, Princess Margaret Cancer Centre, University Health Network, Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan, Department of Surgery, Brigham and Women's Hospital, Boston, MA,
Abstract
Multi-hospital retrospective study comparing gastric adenocarcinoma in Hispanic versus non-Hispanic patients.Org: Olive-View UCLA Medical Center, Department of Surgery, Brigham and Women's Hospital, Boston, MA, David Geffen School of Medicine at UCLA,
Abstract
Is there an increase in elective utilization of non-operative management for rectal cancer?Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, University of Texas MD Anderson Cancer Center, Department of Colon and Rectal Surgery, The University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Radiation Oncology, University of Texas MD Anderson Cancer Center, Department of Gastrointestinal Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, China,
Abstract
Luminal and basal subtyping of circulating tumor cells and influence on outcomes in patients with metastatic castration-resistant prostate cancer.Org: Cedars-Sinai Cancer, Cedars-Sinai Medical Center, Division of Cancer Systems Biology, Department of Surgery, Brigham and Women's Hospital, Boston, MA, California NanoSystems Institute, University of California,
Abstract
Population-based validation of the Melanoma Institute Australia (MIA) and the Memorial Sloan-Kettering Cancer Center (MSKCC) predictive tool for sentinel node status in patients with melanoma.Org: University of Linköping, Linköping University Hospital, Sweden, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Institute of Clinical Sciences,
Abstract
Real-world impact of olaparib use in patients (pts) with advanced pancreatic cancer (PC) harboring germline BRCA1/2 (gBRCA) mutations.Org: University of Verona, Oncology Section, Verona University Hospital Trust (AOUI Verona), IRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele Facoltà di Medicina e Chirurgia, University of Bologna,
Abstract
Clinicogenomic analysis of rare histologic variants of pancreatic carcinoma: Undifferentiated carcinomas with and without osteoclast-like giant cells.Org: University of Michigan, Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy, Division of Hepatopancreatobiliary Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, MA, University of Michigan Health System Comprehensive Cancer Center,
Abstract
Disparities in presentation, treatment, and overall survival for South Asian American patients with colorectal cancer.Org: Department of Surgery, Brigham and Women's Hospital, Boston, MA, University of Wisconsin - Madison, Madison, WI, University of Wisconsin–Madison, University of Wisconsin-Madison Carbone Cancer Center,
Abstract
Immunohistochemical analysis of the tumor microenvironment in acral lentiginous melanoma (ALM).Org: USC Keck School of Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, USC Norris Cancer Hospital, Los Angeles, CA, Department of Radiation Oncology, Sichuan Cancer Hospital & Institute, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China, Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy,
Abstract
Prospective observational study to evaluate lemborexant utility in insomnia among women with breast cancer (WJOG14921B, LUNAR study).Org: Breast Medical Oncology Department, Cancer Institute Hospital of the Japanese Foundation for Cancer Research (JFCR), Tokyo, Japan, The Cancer Institute Hospital of JFCR, Tokyo, Japan, Department of Breast Surgery, Kyorin University School of Medicine/Saitama Medical Center, Tokyo, Japan, Gifu University Hospital, International University of Health and Welfare Narita Hospital, Narita, Japan,
Abstract
Effect of operative time and blood lost on overall survival after pancreaticoduodenectomy.Org: UCSF East Bay, University of California, Davis, Department of Surgery, Brigham and Women's Hospital, Boston, MA, Kaiser Permanente Northern California,
Abstract
The impact of 4R Oncology Model on patient self management and satisfaction in lung versus breast cancer.Org: Center for Business Models on Healthcare, Northwestern University Feinberg School of Medicine, Kaiser Permanente Oakland Medical Center, Division of Research Services, Kaiser Permanente Northern California,
Abstract
The impact of COVID-19 on mortality, length of stay, and cost of care among patients with gastrointestinal malignancies: A propensity score-matched analysis.Org: CHRISTUS Ochsner St. Patrick Hospital, Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Keck Sch of Medicine, Univ of Southern California/Children's Oncology Group, Arcadia, CA, Washington University School of Medicine in St. Louis,
Abstract
Early onset gastric cancer: An analysis of epidemiological and environmental risk factors.Org: Olive-View UCLA Medical Center, Sylmar, CA, Department of Surgery, Brigham and Women's Hospital, Boston, MA, David Geffen School of Medicine at UCLA, Los Angeles, CA,
Abstract
ALUMINUM CONTAINING PARTICLES IN SYNOVIAL FLUID OF PATIENTS WITH NORMAL RENAL FUNCTION AND ALUMINUM ANTACIDS INTAKEOrg: Department of Medicine - Rheumatology Service, Hospital Militar Central, Department of Physics, Mathematics and Biophysics, Comisión Nacional de Energía Atómica, Department of Surgery, Brigham and Women's Hospital, Boston, MA,
Abstract
A PAN-EUROPEAN STUDY OF MUSCULOSKELETAL PAIN: IMPACT ON QUALITY OF LIFE AND BURDEN OF DISEASEOrg: Rheumatology, Royal Cornwall Hospitals Trust, Truro, Academic Rheumatology, University of Bristol, University of Nottingham,
Abstract
ANNEXIN V (A5) AS A NOVEL FACTOR IN MECHANISM OF ATHEROTHROMBOSIS IN SLE AND GENERAL POPULATIONOrg: Department of Medicine, University of Alberta, Alberta, Canada, Center for Infectious Medicine, Karolinska University Hospital, Huddinge University Hospital, Rheumatology Unit and CMM,