Organization
McMaster University
40 clinical trials
Clinical trial
Antibiotic prophyLaxis Versus Placebo in Infants Diagnosed With Hydronephrosis AntenatallyStatus: Active (not recruiting), Estimated PCD: 2024-09-01
Clinical trial
Testing Regional Anesthesia Techniques for Up and Early Discharge Following Knee Arthroplasty: Quality Of Recovery Through Patient Reporting - a Multisite StudyStatus: Not yet recruiting, Estimated PCD: 2026-03-31
Clinical trial
Sputum-guided Treatment With Comprehensive Care Management for Respiratory Improvement to Provide Value and Escalate Care - A Randomized-controlled TrialStatus: Recruiting, Estimated PCD: 2024-09-27
Clinical trial
Mean Visual Acuity Changes Following Five Injections of Aflibercept and the Relationship Between Ocular and Serum Cytokine Levels and Mean Visual Acuity Gains in DME PatientsStatus: Active (not recruiting), Estimated PCD: 2024-09-01
Clinical trial
Single Dose of Antenatal Corticosteroids (SNACS) Randomized Controlled Trial for Pregnancies at Risk of Preterm Delivery: To Keep Babies and Children SafeStatus: Recruiting, Estimated PCD: 2026-12-31
Clinical trial
A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder ComorbidityStatus: Completed, Estimated PCD: 2022-09-30
Clinical trial
Intravenous DNase I for the Treatment of Sepsis: A Phase I Safety and Feasibility Study in ICU PatientsStatus: Recruiting, Estimated PCD: 2025-04-01
Clinical trial
Multi-Nutrient Supplement for Radio-ProtectionStatus: Not yet recruiting, Estimated PCD: 2025-07-01
Clinical trial
Tofacitinib for Hospitalized Acute Severe Ulcerative Colitis Management (the TRIUMPH Study)Status: Active (not recruiting), Estimated PCD: 2023-12-01
Clinical trial
Efficacy of Reslizumab Dose Escalation in Patients With Severe Asthma and Persistent Sputum Eosinophilia Despite Standard Dose TherapyStatus: Completed, Estimated PCD: 2024-01-09
Clinical trial
Investigating the Effects of Probiotics on Synaptic Plasticity in the Follicular and Luteal Phases of the Menstrual CycleStatus: Not yet recruiting, Estimated PCD: 2025-05-01
Clinical trial
The Role of Androgen Deprivation Therapy In Cardiovascular Disease - A Longitudinal Prostate Cancer Study (RADICAL PC1) & A RAndomizeD Intervention for Cardiovascular and Lifestyle Risk Factors in Prostate Cancer Patients (RADICAL PC2)Status: Recruiting, Estimated PCD: 2025-12-01
Clinical trial
Frailty Rehabilitation: A Community-based Intervention to Promote Healthy AgingStatus: Recruiting, Estimated PCD: 2024-08-02
Clinical trial
Ultrasound Guided Sacroiliac Joint Injections With Ketorolac Versus Corticosteroid: A Prospective Non-inferiority StudyStatus: Not yet recruiting, Estimated PCD: 2026-06-01
Clinical trial
Most Effective Opioid Analgesia in Ambulatory Surgeries: a Randomized Control, Investigator Blinded, Parallel Group With Superiority Design Study of Morphine Versus HydromorphoneStatus: Completed, Estimated PCD: 2019-03-01
Clinical trial
Single Dose Antenatal Corticosteroids (SNACS) Pilot Randomized Control Trial for Women at Risk of Preterm BirthStatus: Completed, Estimated PCD: 2021-08-31
Clinical trial
A 9-week Phase 2 Clinical Trial to Evaluate the Safety, Tolerability and Efficacy of Psilocybin-assisted-psychotherapy in Adults With Cannabis Use Disorder: A Proof-of-Concept StudyStatus: Not yet recruiting, Estimated PCD: 2026-03-01
Clinical trial
Restoration of Impaired Microbiota-mediated Aryl Hydrocarbon Receptor Signaling in Celiac Disease by Oral Tryptophan Supplementation: an Exploratory, Pilot TrialStatus: Recruiting, Estimated PCD: 2024-11-01
Clinical trial
Single Blind Clinical Trial: Optimizing TAP Block Timing for Bariatric SurgeryStatus: Not yet recruiting, Estimated PCD: 2024-06-28
Clinical trial
A Two-arm, Placebo-controlled, Randomized Clinical Trial to Evaluate the Effect of Tezepelumab on Airway Structure and Function in Patients With Uncontrolled Moderate-to-severe AsthmaStatus: Recruiting, Estimated PCD: 2024-09-01
Clinical trial
A Randomized Controlled Trial on the Use of Postoperative Extended Venous Thromboprophylaxis in Patients With Inflammatory Bowel Disease: A Pilot StudyStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
Preventing Intravesical Recurrence in Patients With Urothelial Carcinoma of the Upper Urinary Tract: a Pilot Randomized Trial of a Single Prophylactic Bladder Instillation of Mitomycin C After Diagnostic UreteroscopyStatus: Not yet recruiting, Estimated PCD: 2025-09-01
Clinical trial
Re-EValuating the Inhibition of Stress Erosions: Prophylaxis Against Gastrointestinal Bleeding in the Critically Ill (The REVISE) TrialStatus: Completed, Estimated PCD: 2023-10-31
Clinical trial
The Effect of Cannabinoids vs. Placebo on Persistent Post-surgical Pain Following Total Knee Arthroplasty: A Multicenter, Randomized Pilot TrialStatus: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
Probiotic and Antibiotic Therapies in Women With Unexplained InfertilityStatus: Withdrawn, Estimated PCD: 2024-01-01
Clinical trial
Brimonidine/Timolol Fixed Combination Prophylaxis for Intraocular Pressure Elevation Following Intravitreal Injection of Antivascular Endothelial Growth FactorStatus: Withdrawn, Estimated PCD: 2019-01-01
Clinical trial
Pilot Study of Sex-matched vs. Sex-mismatched Red Blood Cell TransfusionStatus: Completed, Estimated PCD: 2022-05-27
Clinical trial
Prospective, Open-label Trial to Evaluate Efficacy of 30-day Duration of Fidaxomicin in Patients With Recurrent C. Difficile InfectionStatus: Terminated, Estimated PCD: 2021-08-30
Clinical trial
Assessing the Effectiveness of Ibuprofen Compared to Morphine as a Pediatric Postoperative Pain Management Tool Following Inguinal Surgery (AIMS)Status: Recruiting, Estimated PCD: 2024-02-01
Clinical trial
A Randomized Pilot Trial Comparing Anti-Thymocyte Globulin (ATG) With ATG Plus Post Transplant Cyclophosphamide (PTCy) for Prophylaxis Against Acute and Chronic Graft Versus Host Disease (GVHD)Status: Recruiting, Estimated PCD: 2024-10-13
Clinical trial
Mepolizumab for the Treatment of Chronic Cough With Eosinophilic Airways DiseasesStatus: Recruiting, Estimated PCD: 2023-12-31
Clinical trial
Caudal vs Local Anesthesia in Hypospadias: The CLASH StudyStatus: Recruiting, Estimated PCD: 2024-01-01
Clinical trial
Phase 1, Open Label Study to Evaluate the Safety and Immunogenicity of ChAd68 and AdHu5 Vector-based Trivalent COVID-19 Vaccines Delivered Via Inhaled AerosolStatus: Active (not recruiting), Estimated PCD: 2024-09-30
Clinical trial
A Multi-Center, Randomized Controlled Trial Comparing The Clinical Effectiveness and Cost-Effectiveness of Collagenase Injection (Xiaflex) and Palmar Fasciectomy in the Management of Dupuytren's DiseaseStatus: Completed, Estimated PCD: 2021-12-17
Clinical trial
A Phase 2 Multi-centre Randomized Double-blind Placebo-controlled Parallel Group Study to Examine the Effects of 24 Weeks Tezepelumab 210 mg sc q4wks on Methacholine Airway Hyperresponsiveness in Participants With Mild Allergic AsthmaStatus: Not yet recruiting, Estimated PCD: 2024-12-30
Clinical trial
The Pharmacokinetics of Oral Tetrahydrocannabinol and Cannabidiol Across the Spectrum of Glomerular Filtration Rate: a PharmacoKinetic StudyStatus: Recruiting, Estimated PCD: 2023-12-31
Clinical trial
Cannabidiol for the Treatment of Anxiety Disorders: An 8-Week Pilot StudyStatus: Recruiting, Estimated PCD: 2023-12-15
Clinical trial
Vancomycin Dosing for Serious MRSA Infections: A Non-inferiority Randomized Trial of Trough Level Versus AUC/MICStatus: Recruiting, Estimated PCD: 2026-01-01
Clinical trial
A Phase 2 Trial to Evaluate Safety and Immunogenicity of a Next-generation COVID-19 Vaccine Delivered by Inhaled Aerosol to HumansStatus: Not yet recruiting, Estimated PCD: 2025-07-01
Clinical trial
SMART (Smallpox Vaccine for Mpox Post-Exposure Prophylaxis: A Cluster Randomized Controlled Trial)Status: Not yet recruiting, Estimated PCD: 2024-12-01