Product
Linaprazan
Aliases
Linaprazan glurate, X842
4 clinical trials
8 indications
Indication
pharmacokineticsIndication
ElectrocardiogramIndication
SafetyIndication
TolerabilityIndication
Gastroesophageal reflux diseaseIndication
Safety IssuesIndication
Drug InteractionIndication
BioavailabilityClinical trial
A Phase I Study to Investigate the Pharmacokinetics and ECG Effects of Two Single Ascending Doses of Linaprazan Glurate Given as Oral Tablets to Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-12-02
Clinical trial
Ph 1, OL, Randomized, Parallel-group Study to Investigate PK and PD (Intragastric pH) of Linaprazan Glurate/Linaprazan After 14 Days Administration of Linaprazan Glurate to Healthy SubjectsStatus: Active (not recruiting), Estimated PCD: 2023-03-24
Clinical trial
Effect of Repeated Dosing of Clarithromycin on PK of Linaprazan Glurate/Linaprazan, Effect of Single Dose of Linaprazan Glurate on PK of Clarithromycin, Single/Repeated Dosing of Linaprazan Glurate on PK of Midazolam to Healthy SubjectsStatus: Completed, Estimated PCD: 2023-05-30
Clinical trial
A Randomized, Single Dose, Crossover Study in Healthy Volunteers to Investigate the Relative Bioavailability of Linaprazan for a New Oral Tablet Formulation of Linaprazan Glurate, and to Assess the Effect of Food on the Pharmacokinetics of LinaprazanStatus: Completed, Estimated PCD: 2022-12-30