Product
Linerixibat
5 clinical trials
2 indications
Indication
PruritusIndication
CholestasisClinical trial
A Two-part, Randomized, Placebo Controlled, Double Blind, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Linerixibat for the Treatment of Cholestatic Pruritus in Participants With Primary Biliary Cholangitis (PBC)Status: Recruiting, Estimated PCD: 2024-10-30
Clinical trial
Long-term Safety and Tolerability Study of Linerixibat for the Treatment of Cholestatic Pruritus in Participants With Primary Biliary CholangitisStatus: Recruiting, Estimated PCD: 2027-02-02
Clinical trial
A Two-part, Phase 1, Open-label, Randomized, Parallel-arm, Fixed Sequence, Drug-drug Interaction Study to Investigate the Effect of Linerixibat on Plasma Concentrations of Obeticholic Acid and Conjugates in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2022-05-31
Clinical trial
A Phase 1, Open-label, Single-dose Study to Evaluate the Pharmacokinetics and Safety of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Matched Control ParticipantsStatus: Completed, Estimated PCD: 2022-12-06