Product
BMS-986278
Aliases
BMS-986278 Placebo
8 clinical trials
5 indications
Indication
Healthy Control ParticipantsIndication
Pulmonary FibrosisIndication
Idiopathic Pulmonary FibrosisIndication
Healthy ParticipantsIndication
Liver ImpairmentClinical trial
A Phase 1, Open-label, Fixed-sequence Study to Investigate the Effects of Multiple Doses of BMS-986278 on the Pharmacokinetics of Combined Oral Contraceptives (Drospirenone/Ethinyl Estradiol) in Healthy Female ParticipantsStatus: Completed, Estimated PCD: 2023-12-11
Clinical trial
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Progressive Pulmonary FibrosisStatus: Recruiting, Estimated PCD: 2027-12-27
Clinical trial
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986278 in Participants With Idiopathic Pulmonary FibrosisStatus: Recruiting, Estimated PCD: 2026-10-26
Clinical trial
A Double-blind, Placebo-controlled, Randomized, Single and Multiple Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of BMS-986278 in Healthy Chinese ParticipantsStatus: Completed, Estimated PCD: 2023-05-23
Clinical trial
A Phase 1, 2-Part, Randomized, Double-Blind, Placebo-controlled, Multiple Dose Study to Test the Potential Interaction of a PDE5 Inhibitor With BMS-986278 and to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BMS-986278 in Healthy Adult Participants (Part 1) and in Japanese Participants (Part 2)Status: Completed, Estimated PCD: 2023-05-02
Clinical trial
A Phase 1, 3-arm, Open-label, Sequential Design Study to Investigate the Effect of Multiple Doses of Itraconazole, Gemfibrozil, or Carbamazepine on Single-dose Pharmacokinetics of BMS-986278 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-10-23
Clinical trial
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 2 Study of the Efficacy and the Safety and Tolerability of BMS-986278 in Participants With Pulmonary FibrosisStatus: Completed, Estimated PCD: 2022-08-04
Clinical trial
A Phase 1, Multi-center, Open-label Study to Assess the Pharmacokinetics and Safety of BMS-986278 in Healthy Participants and Those With Mild, Moderate and Severe Hepatic ImpairmentStatus: Not yet recruiting, Estimated PCD: 2024-12-23