Product
PF614
Aliases
Oxycodone prodrug, PF614 solution, PRF06104
4 clinical trials
3 indications
Indication
pharmacokineticsIndication
Healthy Control ParticipantsIndication
Substance AbuseClinical trial
A Single Dose Study to Evaluate the Pharmacokinetics of Oxycodone and PF614 When PF614 Solution is Co-Administered With Nafamostat, as an Immediate Release Solution and/or Extended Release (ER) Capsule Formulations in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-04-26
Clinical trial
A Phase 1b, Randomized 2-Part Single-Center Study to Evaluate the PK and Safety of Multiple Ascending Oral Doses of PF614 and the Food Effect and BA/BE of Single Oral Doses of PF614 Relative to OxyContin in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-03-21
Clinical trial
A Randomized, Double-blind, Placebo-and Active-Controlled Crossover Study to Evaluate the Intranasal Abuse Potential of PF614 Compared With Immediate-Release Oxycodone and Placebo in Non-Dependent Recreational Opioid UsersStatus: Completed, Estimated PCD: 2022-08-31
Clinical trial
A Randomized, Double-Blind, Placebo- and Active-Controlled Crossover Study to Evaluate the Oral Abuse Potential of PF614 Compared With Oxycodone Immediate-Release Tablets and Placebo in Non-Dependent Recreational Opioid UsersStatus: Completed, Estimated PCD: 2022-12-23