Product
AT-527
Aliases
AT-527 and Probenecid, Bemnifosbuvir
4 clinical trials
4 indications
Indication
Renal ImpairmentIndication
Healthy VolunteerIndication
COVID-19Indication
Healthy Volunteer StudyClinical trial
A Phase 1, Open-Label, Parallel-Group, Single-Dose Adaptive Study to Evaluate the Safety and Pharmacokinetics of AT-527 in Adult Subjects With Normal and Impaired Renal Function Sub-Study: Effects of Probenecid on the Pharmacokinetics of AT-527 in Healthy Adult SubjectsStatus: Recruiting, Estimated PCD: 2024-04-23
Clinical trial
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of AT-527 in Subjects With Moderate COVID-19Status: Terminated, Estimated PCD: 2022-01-10
Clinical trial
A Phase II Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Antiviral Activity, Safety, Pharmacokinetics, and Efficacy of RO7496998 (AT-527) in Non-Hospitalized Adult Patients With Mild or Moderate COVID-19Status: Completed, Estimated PCD: 2021-09-17
Clinical trial
Phase 1, Multiple Dose, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of AT-527 Following Oral Administration Under Fasting Conditions or With a Meal in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-08-23