Target

POLE P286R

11 abstracts

Abstract
Clinical and molecular characterization of microsatellite stable (MSS) tumors in patients with Lynch syndrome (LS).
Org: Memorial Sloan Kettering Cancer Center, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, New York, NY,
Abstract
Evaluation of genomic alterations in early-onset versus late-onset colorectal cancer.
Org: Natera, Inc., Natera, Inc, Vanderbilt-Ingram Cancer Center,
Abstract
A deep learning model for the prediction of microsatellite instability and pathogenic POLE mutations in colorectal cancer using histopathologic images.
Org: Department of GI Oncology, Department of Gastrointestinal Oncology, Peking University Cancer Hospital and Institute, Beijing, China, Peking University Cancer Hospital & Institute, Beijing Advanced Innovation Center for Big Data and Brain Computing, Beihang University,
Abstract
Risk reclassification of endometrial cancer according to molecular profiling: UK single centre experience.
Org: The Royal Marsden Hospital, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, The Royal Marsden Hospital NHS Foundation Trust, Royal Marsden Hospital and Institute of Cancer Research,
Abstract
Effect of somatic-germline genomic integration on the contribution of pathogenic germline genetic variants (gPV) to colorectal cancer (CRC) carcinogenesis.
Org: Memorial Sloan Kettering Cancer Center, New York, NY, Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, New York, NY,
Abstract
3D genomics identifies previously unreported yet clinically actionable gene fusions and complex rearrangements in a cohort of driver-negative colorectal carcinoma tumors.
Org: Arima Genomics, Scripps Clinic/Green Hospital, Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Scripps Clinic and Scripps MD Anderson Cancer Center,
Abstract
The association of progesterone receptor and abnormal p53 expression in endometrioid endometrial cancer.
Org: Linkou Chang Gung Memorial Hospital and Chang Gung University, Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy, Chang Gung Memorial Hospital, Chang Gung University Medical College, Gynecologic Cancer Research Center,
Abstract
Comprehensive analysis of the mutational status of early colon cancer: Real world data from the AIO ColoPredict registry study.
Org: Institut für Pathologie, Georgius Agricola Stiftung Ruhr, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, Winship Cancer Institute of Emory University, Atlanta, GA, Emory University, Atlanta, GA, Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA, Department of Medicine, Massachusetts General Hospital, Boston, MA, Department of Medicine, Emory University School of Medicine, Atlanta, GA, Department of Urology, Emory University School of Medicine, Atlanta, GA, Oncology and Palliative Care Units, Ruhr-University Bochum,