Target
CD28
1 product, 1 indication
Indications
kidney transplantation (1 products)
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1 drug
6 abstracts
Abstract
A phase 1/2 study of REGN7075 in combination with cemiplimab (cemi) in patients (pts) with advanced solid tumors: Efficacy and safety results.Org: Memorial Sloan Kettering Cancer Center, Division of Gynecologic Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, University of Cincinnati Cancer Center, START Midwest, Grand Rapids, MI,
Abstract
Effect of the killing style of individual CAR T cells on the clinicopathological behavior of therapeutic products in the clinic.Org: Center for Cell and Gene Therapy, Texas Children’s Hospital, Houston Methodist Hospital, Department of Pathology and Genomic Medicine, Baylor College of Medicine, University of Houston,
Abstract
Neoadjuvant pembrolizumab, GX-188E, and GX-I7 in patients with human papillomavirus-16- and/or 18-positive head and neck squamous cell carcinoma: Single-arm, phase 2 trial with single cell transcriptomic analysis and artificial intelligence-powered spatial analysis.Org: Genome Insight Inc., Heavy Ion Research Institute, Korea Advanced Institute of Science and Technology, Lunit Inc.,
Abstract
Phase 2 study of abatacept, ixazomib, and dexamethasone in patients with relapsed/refractory multiple myeloma.Org: Roswell Park Comprehensive Cancer Center, IU Simon Comprehensive Cancer Center, Vanderbilt-Ingram Cancer Center,
Abstract
Dysregulation of immune checkpoint proteins in patients with newly diagnosed early breast cancer undergoing neoadjuvant chemotherapy: A comparison between patients with triple negative breast cancer (TNBC) and non-TNBC.Org: The Medical Oncology Centre of Rosebank, Johannesburg, South Africa, Department of Immunology, Faculty of Health Science, University of Pretoria, Pretoria, South Africa, University of Pretoria, Department of Immunology, Pretoria, South Africa, Netcare, City of Johannesburg, South Africa, Drs Gritzman and Thatcher Inc. Pathology Laboratory, City of Johannesburg, South Africa,
Abstract
"Armed" CEA CAR-T with a SIRPγ-CD28 chimeric co-receptor to exhibit the enhanced antitumor activity in preclinical study of colorectal cancer.Org: Chongqing Precision Biotech Co., Ltd.,
Drug
belatacept