Target
APC
25 abstracts
Abstract
A clinical-genetic (CG) circulating tumor DNA (ctDNA)-based prognostic model for predicting overall survival (OS) in men with metastatic castrate-resistant prostate cancer (mCRPC) treated with potent androgen receptor inhibition (Alliance).Org: Department of Biostatistics and Bioinformatics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Duke Cancer Institute Center for Prostate and Urologic Cancers, Duke University School of Medicine, Duke University Medical Center, Duke University Department of Biostatistics and Bioinformatics,
Abstract
Clinicopathological characteristics and survival in metastatic colorectal cancer with short-form APC mutations.Org: Department of Gastroenterological Chemotherapy, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan, Translational Research Support Office, Division of Drug and Diagnostic Development Promotion, Department for the Promotion of Drug and Diagnostic Development, National Cancer Center Hospital East, Kashiwa, Japan, National Cancer Center Hospital East, Kashiwa, Japan, Genomic Medicine, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan, Department of Medical Oncology, The Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan, Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan, Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan,
Abstract
Impact of DNA damage repair alterations on real-world response to therapy in metastatic colorectal cancer.Org: Huntsman Cancer Institute, University of Utah Health, Salt Lake City, UT, Department of Internal Medicine C, University Hospital Greifswald, Greifswald, Germany,
Abstract
Characterization of cell-free circulating tumor DNA in patients with brain metastases.Org: UC San Diego Moores Cancer Center, Center for Personalized Cancer Therapy and Division of Hematology and Oncology, UCSD Moores Cancer Center, UC San Diego Medical Center, UC San Diego,
Abstract
Cancer of unknown primary with gastrointestinal profiles: A distinct CUP subset.Org: Baylor College of Medicine, University of Texas MD Anderson Cancer Center, MD Anderson Cancer Center, MD Anderson Cancer Center Hematology/Oncology, The University of Texas MD Anderson Cancer Center, Stem Cell Transplantation Rsch, Houston, TX,
Abstract
Novel deep learning–based prognostic prediction model for colorectal cancer using hematoxylin and eosin–stained whole slide images.Org: Biomy Inc., Tokyo, Japan, Akita University Graduate School of Medicine, Akita, Japan, Keio University School of Medicine,
Abstract
Evaluation of genomic alterations in early-onset versus late-onset colorectal cancer.Org: Natera, Inc., Natera, Inc, Vanderbilt-Ingram Cancer Center,
Abstract
Genomic landscapes of early-onset versus average-onset colorectal cancer populations.Org: Mayo Clinic, Department of Quantitative Science Research, Vanderbilt-Ingram Cancer Center, University of Colorado Cancer Center, Tempus Labs, Inc.,
Abstract
A systematic comparison of whole genome sequencing and targeted panel sequencing for precision oncology.Org: Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Genome Insight, San Diego, CA, Seoul National University Cancer Research Institute, Seoul, Republic of Korea, Department of Thoracic and Cardiovascular Surgery,
Abstract
Implementation of universal pan-cancer germline genetic testing in an Arab population: The Jordanian Exploratory Cancer Genetics (Jo-ECAG) study.Org: King Hussein Cancer Center, Invitae, King Hussein Medical Center,
Abstract
Trends in the needs and clinical utility of comprehensive genomic profiling test in rare cancers before and after the National Health Insurance coverage in Japan.Org: National Cancer Center Hospital East, Kashiwa, Japan, National Cancer Center Research Institute,
Abstract
Screening the key pathogenic mutations in Chinese patients with colorectal cancers using liquid and tissue biopsy.Org: Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy, The First Affiliated Hospital of Harbin Medical University, Harbin, China, HaploX Biotechnology, Shenzhen, China, Shenzhen TargetRx,
Abstract
Genomic characterization in gastrointestinal cancer patients based on cfDNA sequencing.Org: Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy, Longgang District People's Hospital, HaploX Biotechnology, Shenzhen, China,
Abstract
Effect of somatic-germline genomic integration on the contribution of pathogenic germline genetic variants (gPV) to colorectal cancer (CRC) carcinogenesis.Org: Memorial Sloan Kettering Cancer Center, New York, NY, Clinical Genetics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, Division of Solid Tumor Oncology, Memorial Sloan Kettering Cancer Center, New York, NY,
Abstract
Clinical and genomic characteristics between DDR germline and somatic mutations in pan-cancer.Org: Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd., The State Key Lab of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd, Nanjing, China,
Abstract
Spectrum of germline pathogenic variants among patients with cancer in Mexico.Org: Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubirán, Mexico City, Mexico, National Institute of Medical Sciences and Nutrition Salvador Zubirán, City of Hope National Medical Center, Latin American School of Oncology,
Abstract
Intratumoral heterogeneity as a predictive biomarker in immunotherapy for advanced esophageal cancer.Org: Department of Oncology and Haematology, Division of Oncology, University Hospital of Modena, Modena, Italy, Shanghai East Hospital, Tongji University, Shanghai, China, Tongji Universtity School of Medicine,
Abstract
Thoracic SMARCA4-deficient undifferentiated tumor: A clinicopathologic study.Org: University of Kansas Medical Center, Department of Biostatistics & Data Science, Kansas City, MO, KSQ Therapeutics, Cambridge, MA,
Abstract
Comprehensive multigene profiling impact on clinical decisions in patients with advanced cancers: A multicenter, retrospective analysis.Org: Federal State Budgetary Institution N.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation (N.N. Blokhin NMRCO), OncoAtlas LLC, Federal State Budgetary Institution "N.N. Blokhin National Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation (N.N. Blokhin NMRCO),
Abstract
3D genomics identifies previously unreported yet clinically actionable gene fusions and complex rearrangements in a cohort of driver-negative colorectal carcinoma tumors.Org: Arima Genomics, Scripps Clinic/Green Hospital, Department of Hematology and Oncology, University Hospital Mannheim, Heidelberg University, Scripps Clinic and Scripps MD Anderson Cancer Center,
Abstract
Serial ctDNA monitoring to predict response in mCRC patients treated with anlotinib in combination with oxaliplatin and capecitabine (CAPEOX) as the first-line therapy.Org: Cancer Center Zhejiang University, Jiangsu Simcere Diagnostics Co., Ltd., Nanjing Simcere Medical Laboratory Science Co., Ltd., State Key Laboratory of Translational Medicine and Innovative Drug Development, Jiangsu Simcere Diagnostics Co., Ltd,
Abstract
The landscape of ATM alteration in Chinese solid tumor patients.Org: Ya’an People’s Hospital, Yinfeng Gene Technology Co Ltd, Huaxi Kindstar Medical Diagnostics (Sichuan) Co Ltd, Clinical Oncology Research Alliance,
Abstract
Commercial next generation sequencing in a real-world cohort of patients with metastatic breast cancer.Org: Renaissance School of Medicine at Stony Brook University, Stony Brook University Hospital - Cancer Center,
Abstract
Prevalence and clinical correlations of Lynch syndrome (LS) in northeast Brazil.Org: Instituto do Câncer do Ceará ICC, Universidade de Fortaleza/UNIFOR, Fortaleza, Brazil, Instituto do Câncer do Ceará/ICC, Cancer Insititute of Ceará,
Abstract
Frequency of pathogenic germline variants in cancer susceptibility genes in 841 renal cell carcinoma cases.Org: AcornMed Biotechnology Co., Ltd., Beijing, China,