Target
Smoothened
6 abstracts
Abstract
Phase 1 study of anti–immunoglobulin-like transcript 3 (ILT3) monoclonal antibody (mAb) MK-0482 + pembrolizumab (pembro) in patients with recurrent inoperable glioblastoma (GBM).Org: Seoul National University Hospital, Asan Medical Center, University of Ulsan College of Medicine, John Theurer Cancer Center at Hackensack Meridian Health, Hackensack University Medical Center,
Abstract
Molecular profiling of ctDNA from NCI-MATCH patients enrolled for treatment with mTOR1/2 inhibitor sapanisertib (arm M) and the Hedgehog pathway inhibitor vismodegib (arm T).Org: Illumina, Inc., Molecular Characterization Laboratory, Frederick National Laboratory for Cancer Research, National Cancer Institute, Vilnius, Lithuania, Biometric Research Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD,
Abstract
Comprehensive CRISPR-enabled functional genomics profiling to identify targetable cancer genes in primary acute myeloid leukemia (AML).Org: Function Oncology, San Diego State University Department of Biology, San Diego, CA, Cambridge University Hospitals NHS Foundation Trust,
Abstract
A systematic comparison of whole genome sequencing and targeted panel sequencing for precision oncology.Org: Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Genome Insight, San Diego, CA, Seoul National University Cancer Research Institute, Seoul, Republic of Korea, Department of Thoracic and Cardiovascular Surgery,
Abstract
Disparities in uptake of novel therapies for acute myeloid leukemia.Org: Division of Population Sciences, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, Dana-Farber Cancer Institute,
Abstract
Genomic analysis in NF2 meningiomas: Does co-mutation suggest new subgroups?Org: Department of Pathology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, China, Nanjing Simcere Medical Laboratory Science Co., Ltd, Nanjing, China, The Medical Department, Nanjing Simcere Medical Laboratory Science Co., Ltd, Nanjing, China,