Target
PDGFRA
23 abstracts
Abstract
Revealing and targeting metabolic drivers contributing to treatment escape in diffuse midline glioma.Org: Division of Pre-Clinical Innovation Chemistry Technologies, National Center for Advancing Translational Sciences,
Abstract
A phase 2 clinical trial of regorafenib in patients with advanced pretreated melanoma (RegoMel).Org: Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel,
Abstract
DCC-3116 in combination with ripretinib for patients with advanced gastrointestinal stromal tumor: A phase 1/2 study.Org: The Cancer & Hematology Centers,
Abstract
Correlation between imatinib trough concentration and efficacy in patients with advanced GIST with different genotypes.Org: The First Affiliated Hospital of USTC, Anhui Provincial Hospital, Hefei, China, Sun Yat-sen University Cancer Center Gansu Hospital, Center of Gastrointestinal Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China,
Abstract
Famitinib for familial adenomatous polyposis-associated aggressive desmoid tumors: A single-center exploratory study.Org: Department of Gastrointestinal Oncology, Peking University Cancer Hospital and Institute, Beijing, China, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Jiangsu Hengrui Pharmaceuticals Co., Ltd., Shanghai, China, Gracell Biotechnologies, Ltd.,
Abstract
Clinical efficacy of avapritinib in gastrointestinal stromal tumors (GIST) with different KIT genotypes: Post hoc analysis of the phase 1 NAVIGATOR and phase 1/2 CS3007-101 trials.Org: Portland VA Health Care System, OHSU Knight Cancer Institute, Portland, OR, Department of Gastrointestinal Oncology, Peking University Cancer Hospital and Institute, Beijing, China, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, The First Affiliated Hospital of Sun Yat-sen University,
Abstract
Geographical and baseline clinical characteristics of participants enrolled in hepatocellular carcinoma (HCC) trials: Analysis of US FDA approvals.Org: FDA/CDER, U.S. Food and Drug Administration, US Food and Drug Administration, Oncology Center of Excellence, Office of New Drugs,
Abstract
Longitudinal follow-up and outcomes of pediatric and adult patients with SDH-deficient GIST.Org: Pediatric Oncology Branch, Clinical Center National Institutes of Health, Center for Cancer Research, National Cancer Institute, Surgical Oncology Program, Developmental Therapeutics Branch, National Cancer Institute, Vilnius, Lithuania,
Abstract
Efficacy and safety of anlotinib combined with anthracycline and ifosfamide followed by anlotinib maintenance in advanced soft tissue sarcoma: A single-arm, phase 2 trial.Org: Rare Tumors Department, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Huaiyin District Jinan, China, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Science, Jinan, Shandong, China, Shandong First Medical University and Shandong Academy of Medical Sciences, Huaiyin District Jinan, Jinan,
Abstract
Fluorine-18 fluorodeoxyglucose (18FDG)-uptake assessment of PDGFRA mutant gastrointestinal stromal tumors (GIST): A retrospective multicenter Italian study.Org: Oncology Unit S. Chiara Hospital, Trento, Italy, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy, Adult Mesenchymal Tumour & Rare Cancer Medical Oncology Unit, Istituto Nazionale Tumori, Milan, Italy, Adult Mesenchymal Tumour & Rare Cancer Medical Oncology Unit, Istituto Nazionale Tumori, Italy, Milan, Italy, Medical Oncology and Hematology Unit, Humanitas Cancer Center, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy,
Abstract
Outcomes in patients with advanced gastrointestinal stromal tumor who did not have baseline ctDNA detected in the INTRIGUE study.Org: Sylvester Comprehensive Cancer Center, University of Miami Health System, Miami, FL, Sarcoma Unit, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, United Kingdom, Dana-Farber Cancer Institute, Boston, MA, USA, Leiden University Medical Center, Leiden, Netherlands, University Hospitals Leuven, Department of General Medical Oncology, Leuven Cancer Institute, KU Leuven, Leuven, Belgium,
Abstract
Multi-omic characterization of gastrointestinal stromal tumor (GIST) in a large real-world patient cohort.Org: Sylvester Comprehensive Cancer Center, Miami, FL, University of Miami Miller School of Medicine, Miami, FL, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Caris Life Sciences, Irving, TX, Lombardi Comprehensive Cancer Center,
Abstract
Clinical utility of liquid-based comprehensive genomic profiling (CGP) in gastrointestinal stromal tumors (GIST).Org: Boston Medical Center, Foundation Medicine, Inc., Cambridge, MA, Boston University Medical Campus, OHSU Knight Cancer Institute, Portland, OR,
Abstract
Identification of SNVs via targeted comprehensive genome profiling in patients with brain cancer.Org: One Cell Dx, School of Consciousness Studies, MIT-WPU, Pune, India, Dr. D.Y. Patil Vidyapeeth, OneCell Dx,
Abstract
Clinicopathological features and treatment profile of patients referred to a sarcoma medical oncology centre in India: Challenges and insights from the developing world.Org: All India Institute of Medical Sciences, Delhi, India, All India Institute of Medical Sciences, New Delhi, India,
Abstract
Efficacy and safety of ripretinib in Chinese patients with advanced gastrointestinal stromal tumors (GIST) as ≥4th line therapy: Long-term update from a single-arm, phase 2 trial.Org: Peking University Cancer Hospital & Institute, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Fujian Medical University Union Hospital, The First Affiliated Hospital of Chongqing Medical University, Fudan University Shanghai Cancer Center,
Abstract
Predicting the immunotherapy response based on molecular subtypes of pan-immune signatures in gastrointestinal stromal tumor.Org: ChosenMed Technology (Zhejiang) Co., Ltd., Beijing InnoCare Pharma Tech, China National Biotec Group,
Abstract
Comprehensive genomic and transcriptomic profiling analysis of the recurrent gastrointestinal stromal tumor (GIST).Org: ChosenMed Technology (Zhejiang) Co., Ltd., Chinese People’s Liberation Army General Hospital, Beijing Tongren Hospital, Siping Central People’s Hospital,
Abstract
Identification of clinically actionable biomarkers in an Indian cancer cohort using comprehensive genomic profiling (CGP): An institutional experience.Org: Triesta Sciences, HCG Cancer Center Mumbai, Strand Life Sciences,
Abstract
Camrelizumab combined with lenvatinib and RALOX-HAIC for hepatocellular carcinoma (HCC) in BCLC stage B and C: A prospective, single-arm, phase II trial (Cal Era study).Org: Hepatology Unit and Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, China, Nanfang Hospital, Southern Medical University, Guangzhou, China, Hepatology Unit and Department of Infectious Diseases, Nanfang Hospital Southern Medical University, Guangzhou, China, Department of Infectious Diseases, State Key Laboratory of Organ Failure Research, Guangdong Provincial Key Laboratory of Viral Hepatitis Research, Nanfang Hospital, Southern Medical University, Guangzhou, China,
Abstract
Ripretinib therapy in treating advanced gastrointestinal stromal tumors: A single-center analysis in a real-world setting.Org: The First Affiliated Hospital of Sun Yat-sen University, The First Affiliated Hospital of USTC, Anhui Provincial Hospital, Hefei, China, The Seventh Affiliated Hospital of SunYat-sen University,
Abstract
Comparing GIST outcomes between geriatric and non-geriatric patients: A population-based analysis.Org: Worcester Academy, Northwell Health, New Hyde Park, NY, Northwell Heath,
Abstract
Genomic landscape of cancer of unknown primary site (CUP): Mayo Clinic experience.Org: Mayo Clinic, Mayo Clinic, Department of Laboratory Medicine and Pathology, Mayo Clinic, Mankato,