Compression Garments in the Community With POTS

REB20-2224

Compression Garments are a commonly prescribed treatment in Postural Orthostatic Tachycardia Syndrome (POTS). The effectiveness of a proof-of-concept compression garment has been demonstrated in an acute laboratory setting. It is not known if commercially available compression garments that participants wear in their every day lives are effective at improving heart rate and reducing symptoms in POTS. This trial will evaluate the use of commercially available waist-high and abdominal compression garments in adults diagnosed with POTS in a community setting.

2021-05-17

2024-12-31

2024-12-31

Recruiting

30

Inclusion Criteria: * Physician diagnosis of Postural Tachycardia Syndrome (POTS) * Resident of Canada * Owns waist-high compression garment: medical grade or commercially available tights with a pressure rating provided (e.g. 15-18 mmHg, 20-30 mmHg, 30-40 mmHg) * Optional Sub-Study: owns an abdominal compression garment (e.g. abdominal shapewear, waist high shorts) * Able to participate in a 4-day study (2x2 day segments with a 5-day washout period) Exclusion Criteria: * Overt cause for postural tachycardia (i.e., acute dehydration, thyroid disease) that precludes POTS diagnosis * Not a resident of Canada * Participants with somatization or severe anxiety symptoms will be excluded * Pregnant (self-reported) * Inability to tolerate compression garments for the duration of the study * Does not own a waist-high compression garment * Other factors which in the investigator's opinion would prevent the participant from completing the protocol, including poor compliance during previous studies

{'studyType': 'INTERVENTIONAL', 'phases': ['NA'], 'designInfo': {'allocation': 'RANDOMIZED', 'interventionModel': 'CROSSOVER', 'interventionModelDescription': 'This study will investigate the effects waist high compression garments and medications compared to waist-high compression garments and medications held. Participants will cross-over and complete both arms. If participants participate in the abdominal compression sub-study, the order of waist-high compression - abdominal compression will also be randomized.', 'primaryPurpose': 'TREATMENT', 'maskingInfo': {'masking': 'NONE', 'maskingDescription': 'It is not possible to mask participants to the compression garment intervention.'}}, 'enrollmentInfo': {'count': 30, 'type': 'ESTIMATED'}}

2024-05-09