Organization
University of Calgary
52 clinical trials
19 abstracts
Abstract
Randomized double-blind, placebo-controlled study of topical diclofenac in prevention of hand-foot syndrome in patients receiving capecitabine.Org: All India Institute of Medical Sciences, Dr. Brairch, Abbisko Therapeutics, Department of Medical Oncology, State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, All India Institute of Medical Science (AIIMS),
Abstract
Cost-utility of geriatric assessment in older adults with cancer: Results from the 5C trial.Org: Lawrence S. Bloomberg Faculty of Nursing, Turpanjian College of Health Sciences, Western University, McMaster University and Juravinski Cancer Centre, Bruyere Research Institute,
Clinical trial
Efficacy of a Single Infusion of Zoledronic Acid to Mitigate the Rebound Effect of Rapid Bone Loss Following Denosumab Treatment DiscontinuationStatus: Active (not recruiting), Estimated PCD: 2024-07-01
Clinical trial
A Randomized Placebo-controlled Trial of Adjunctive D-Cycloserine and Accelerated Intermittent Theta Burst Stimulation for Emerging Adults With Suicidal IdeationStatus: Recruiting, Estimated PCD: 2026-07-01
Clinical trial
VERIFY: Vedolizumab for the Prevention of Immune Checkpoint Inhibitor Related Diarrhea or Colitis in Patients With Cancer: A Randomized, Double-Blinded, Placebo Controlled TrialStatus: Not yet recruiting, Estimated PCD: 2026-11-01
Clinical trial
PATHFINDER: A Pragmatic, Active-comparator, Parallel-group, Randomized Trial to Evaluate the Optimal First-line Treatment Strategy for Moderate-to-Severely Active Ileal-dominant Crohn's DiseaseStatus: Recruiting, Estimated PCD: 2027-07-30
Clinical trial
A Phase II Pilot Study of Nonmyeloablative Conditioning Hematopoietic Stem Cell Transplantation in Children With Sickle Cell Disease Who Have a Matched Related Major ABO-Incompatible Donor (Sickle-AID)Status: Recruiting, Estimated PCD: 2028-07-01
Abstract
Real-world treatment practices in patients with muscle invasive bladder cancer (MIBC) treated in Alberta, Canada.Org: University of Calgary, Department of Surgical Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan, Princess Margaret Cancer Center, University Health Network, University of British Columbia,
Clinical trial
A Randomized Sham and Placebo-controlled Trial of Adjunctive D-cycloserine in Repetitive Transcranial Magnetic Stimulation for Obsessive Compulsive DisorderStatus: Active (not recruiting), Estimated PCD: 2024-10-01
Clinical trial
Oral Amiodarone for Acute Cardioversion of Atrial Fibrillation StudyStatus: Recruiting, Estimated PCD: 2027-12-31
Clinical trial
Local Anesthetic Response in Ehlers-Danlos Syndrome (EDS) and Healthy VolunteersStatus: Active (not recruiting), Estimated PCD: 2025-01-01
Clinical trial
The Differential Effects of THC vs. CBD on Cognition in Persons With MSStatus: Not yet recruiting, Estimated PCD: 2025-09-01
Clinical trial
A Pharmacokinetic Study of Adjunctive D-cycloserine to Intermittent Theta Burst Stimulation in Major Depressive DisorderStatus: Completed, Estimated PCD: 2023-06-22
Clinical trial
Mechanisms Supporting Psilocybin-assisted Psychotherapy for Alcohol Use Disorder: A Randomized, Controlled Clinical TrialStatus: Recruiting, Estimated PCD: 2027-10-01
Clinical trial
Efficacy and Safety of Budesonide MMX® vs. Budesonide CR for Induction of Remission in Microscopic Colitis: A Prospective, Randomized, Active Comparator Pilot StudyStatus: Not yet recruiting, Estimated PCD: 2026-09-01
Clinical trial
Investigating Hypercapnia to Treat Neurogenic Orthostatic HypotensionStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
Novel Use of Probenecid to Alleviate Symptoms of Opioid Withdrawal in People With Chronic Pain Undergoing Voluntary Opioid Tapering: a Pilot StudyStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
PrEvention of Posttraumatic Joint contractuRes With Ketotifen 2Status: Active (not recruiting), Estimated PCD: 2024-09-29
Clinical trial
A Clinical Trial to Evaluate the Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Major Depressive DisorderStatus: Recruiting, Estimated PCD: 2024-03-04
Clinical trial
A Multicentre, Prospective, Randomized, Open Label, Blinded-endpoint Trial to Optimize the Use of Intravenous Tenecteplase in Participants With Acute Ischemic Stroke (ACT-GLOBAL THROMBOLYSIS (ACT WHEN-001) Within A Multi-faCtorial, mulTi-arm, Multi-staGe, Randomised, gLOBal Adaptive pLatform Trial for Stroke (ACT-GLOBAL) NCT06352632Status: Not yet recruiting, Estimated PCD: 2030-09-30
Clinical trial
Preemptive Therapy of Graft-vs-Host Disease Using Rabbit Antithymocyte GlobulinStatus: Terminated, Estimated PCD: 2017-06-30
Clinical trial
Ultrasound Guided Platelet Rich Plasma Injections for Post Traumatic Greater Occipital Neuralgia: A Randomized Controlled Pilot StudyStatus: Completed, Estimated PCD: 2023-12-01
Clinical trial
Randomized, Prospective, Placebo-Controlled, Crossover Study of Ondansetron in the Prevention of Sleep Syncope: The Nineth Prevention of Syncope Trial (POST9)Status: Not yet recruiting, Estimated PCD: 2026-12-31
Clinical trial
SPG Block Versus Placebo to Manage Anxiety at Electronic Dance Music FestivalsStatus: Not yet recruiting, Estimated PCD: 2026-05-06
Clinical trial
Multicentre, Prospective Randomized Open Label, Blinded-endpoint (PROBE) Controlled Trial of Thrombolysis With Low Dose Tenecteplase (TNK-tPA) Versus Standard of Care in Minor Ischemic Stroke With Proven Acute Symptomatic OcclusionStatus: Active (not recruiting), Estimated PCD: 2024-01-19
Clinical trial
A Pilot Study of Low Dose Naltrexone Use in Patients With Postural Orthostatic Tachycardia SyndromeStatus: Not yet recruiting, Estimated PCD: 2028-06-01
Clinical trial
Multi-dose Oral Ondansetron For Pediatric Gastroenteritis: A Pragmatic Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
A Pilot Study Assessing the Feasibility of a Randomized Controlled Trial Evaluating Aspirin in Postpartum Women at Risk of Developing Venous ThromboembolismStatus: Completed, Estimated PCD: 2023-09-05
Clinical trial
A Randomized Controlled Trial of Adjunctive D-Cycloserine to Intermittent Theta-burst Stimulation Transcranial Magnetic Stimulation in FibromyalgiaStatus: Active (not recruiting), Estimated PCD: 2026-12-01
Clinical trial
The REDUCED-I Pilot Trial: REDucing the Utilization of CEsarean Sections With InductionStatus: Completed, Estimated PCD: 2024-02-15
Clinical trial
Motor Plasticity Enhancement of Spaced iTBS Trains: a Randomized, Placebo-controlled, Crossover Trial of D-cycloserine.Status: Completed, Estimated PCD: 2021-10-06
Clinical trial
A Randomized, Prospective, Placebo-Controlled, Crossover Study of Atomoxetine in the Prevention of Vasovagal Syncope (POST7)Status: Recruiting, Estimated PCD: 2026-09-01
Clinical trial
Compression Garments in the Community With POTSStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
A Randomized Crossover Study of Propranolol Versus Ivabradine in Postural Tachycardia Syndrome (POTS)Status: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
A Randomized Controlled Trial of Two Hepatitis A Vaccine Doses Among Adolescents With Juvenile Idiopathic Arthritis and Crohn's Disease on Immunosuppressive Therapy: A Pilot StudyStatus: Completed, Estimated PCD: 2023-06-01
Clinical trial
Intravenous Ketorolac Vs. Morphine In Children Presenting With Acute Abdominal Pain And/or Suspected Appendicitis: A Multi-centre Non-Inferiority Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2029-01-01
Clinical trial
The Pathophysiological Role of Adrenergic Antibodies in Postural Tachycardia Syndrome (Aims #1&2)Status: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
A Pilot Clinical Trial of a New Neuromodulation Device for Acute Attacks of Migraine in Children and Adolescents Visiting the Emergency DepartmentStatus: Active (not recruiting), Estimated PCD: 2024-03-01
Clinical trial
Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical InterventionStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
Cannabis for the Prophylactic Treatment of Migraine: a Randomized Double-Blind Placebo-Controlled Clinical TrialStatus: Not yet recruiting, Estimated PCD: 2026-06-01
Clinical trial
Infiltration Between the Popliteal Artery and the Capsule of the Knee (iPACK) With Local Infiltration of Analgesia (LIA) and Adductor Canal Block (ACB) Improves Postoperative Pain in Total Knee Arthroplasty: A Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2024-05-30
Clinical trial
Closed-Loop Insulin Delivery Postpartum in Mothers With Type 1 Diabetes and Their Babies' Feeding PracticesStatus: Completed, Estimated PCD: 2023-02-28
Clinical trial
Treatment of Lower Leg Anterolateral Chronic Exertional Compartment Syndrome With Intra-muscular Botulinum Injections.Status: Not yet recruiting, Estimated PCD: 2023-10-01
Clinical trial
Efficacy of Ultrasound-guided Transversalis Fascia Plane Blocks for Post-cesarean Section Analgesia: a Randomized Double Blinded Control StudyStatus: Completed, Estimated PCD: 2022-10-13
Clinical trial
Hormone Therapy and Angiotensin-Dependent Arterial and RenalStatus: Recruiting, Estimated PCD: 2025-11-30
Clinical trial
Canadian Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of Nosocomial Acquired COVID-19 PatientsStatus: Terminated, Estimated PCD: 2022-01-31
Clinical trial
An Initial Clinical Study to Treat Postictal SymptomsStatus: Recruiting, Estimated PCD: 2025-01-01
Clinical trial
Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging SubjectsStatus: Active (not recruiting), Estimated PCD: 2021-03-01
Clinical trial
Open-Label Trial of Minocycline in Early Multiple Sclerosis: Confirmation of Treatment BenefitStatus: Terminated, Estimated PCD: 2022-12-16
Clinical trial
HIP Fracture Oral thromboPROphylaxis: A Pilot Randomized Controlled Trial (Hip PRO Pilot)Status: Not yet recruiting, Estimated PCD: 2025-03-01
Clinical trial
Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke: QuICR & OPTIMISE Registry Based Pragmatic Randomized Controlled TrialStatus: Completed, Estimated PCD: 2022-04-26
Clinical trial
A Proof of Principle Study of Ondansetron for the Prevention of Vasovagal Syncope: The Eleventh Prevention of Syncope Trial (POST11)Status: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
Vernakalant Versus Amiodarone for Post-operative Atrial Fibrillation in Cardiac Surgery PatientsStatus: Not yet recruiting, Estimated PCD: 2025-01-01
Abstract
Identification of cytokines associated with response and cytokine release syndrome: Analysis of MagnetisMM-3 cohort A.Org: Arnie Charbonneau Cancer Institute, University of Calgary, University of Calgary, Clinica Universidad de Navarra, Pfizer SLU, Pfizer Oncology Division,
Abstract
How reliable are post-mastectomy breast reconstruction videos on YouTube?Org: McGill University Health Center, University of Calgary, McGill University Health Centre Research Institute, St Mary's Research Centre,
Abstract
Characterizing progression to subsequent lines of therapy in metastatic renal cell carcinoma (mRCC) after nivolumab plus ipilimumab (Nivo+Ipi): Results from the International mRCC Database Consortium (IMDC).Org: Tom Baker Cancer Centre, University of Calgary, BC Cancer Agency Vancouver Island Centre, University Hospital of Southern Denmark, University of Bari 'A. Moro',
Abstract
Real-world outcomes among patients with advanced/metastatic renal cell carcinoma (mRCC) treated with cabozantinib or other tyrosine kinase inhibitors (TKIs) after checkpoint inhibitor (CPI) therapy.Org: University of Calgary, Texas Oncology PA, Ipsen, Ontada, McMaster University and Juravinski Cancer Centre,
Abstract
Incidence, outcomes, and risk factors of acute immune checkpoint inhibitor (ICI) pneumonitis post-chemoradiation with durvalumab for patients with locally advanced non-small cell lung cancer (LA-NSCLC): A population-based multicenter study.Org: University of Calgary, Cross Cancer Institute, Tom Baker Cancer Center, Tom Baker Cancer Centre,
Abstract
Clinical analysis of optimized neural network risk models to predict clinically significant prostate cancer and avoid unnecessary prostate biopsies.Org: Nanostics Inc., University of Alberta, University of Calgary, Division of Urology, Department of Surgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, Johns Hopkins Kimmel Cancer Center,
Abstract
Real-world multicentre analysis of patients with hepatocellular carcinoma (HCC) treated with atezolizumab and bevacizumab (A+B): Efficacy, esophagogastroduodenoscopy (EGD) uptake and bleeding complications.Org: Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, University Health Network, University of Toronto, Tom Baker Cancer Centre,
Abstract
Genomic analysis to identify determinants of inherent response and resistance to elranatamab in MagnetisMM-3 cohort A.Org: Arnie Charbonneau Cancer Institute, University of Calgary, University of Calgary, St. Vincent’s Hospital, University of Melbourne, University Medical Center of Hamburg-Eppendorf,
Abstract
Elranatamab, a B-cell maturation antigen (BCMA)-CD3 bispecific antibody, for patients (pts) with relapsed/refractory multiple myeloma (RRMM): Extended follow up and biweekly administration from the MagnetisMM-3 study.Org: Sorbonne University and Saint-Antoine Hospital, Hôpital Saint-Antoine, INSERM UMRs938, Holden Comprehensive Cancer Center, University of Iowa Hospitals & Clinics,
Abstract
Accrual of adolescents and young adults (AYA) into cancer clinical trials in Canada.Org: Canadian Cancer Trials Group, University of Calgary, The Children's Hospital of Eastern Ontario, Research Institute of McGill University Health Centre, CancerCare Manitoba,
Abstract
Canadian (CAN) real-world outcomes for relapsed/recurrent (R/R) metastatic triple-negative breast cancer (mTNBC) in the first-line or later (1L+) setting by early or late recurrence status.Org: Gilead Sciences Canada, University of Calgary, Gilead Sciences Europe Ltd.,
Abstract
Darolutamide observational (DAROL) study in patients with nonmetastatic castration-resistant prostate cancer: Second interim analysis.Org: Fred Hutchinson Cancer Research Center, University of Washington and Fred Hutchinson Cancer Research Centre, Associated Medical Professionals of NY, Toho University Sakura Medical Center, First Urology,
Abstract
Imaging response to immune checkpoint inhibitors in patients with advanced melanoma: A retrospective observational cohort study.Org: Arnie Charbonneau Cancer Research Institute, University of Calgary, Department of Medicine, Icahn School of Medicine at Mount Sinai, University of Alberta, Tom Baker Cancer Centre,
Clinical trial
Bacteriophage Therapy for Methicillin-Sensitive Staphylococcus Aureus Prosthetic Joint InfectionStatus: Not yet recruiting, Estimated PCD: 2025-06-01
Clinical trial
PDE4 Inhibition and Theta-burst Stimulation Transcranial Magnetic Stimulation Motor Plasticity: a Randomized Placebo-controlled Single-blind Crossover StudyStatus: Not yet recruiting, Estimated PCD: 2025-08-01
Abstract
AZD3582 PRODUCES FEWER AND SMALLER GASTRIC ULCERS THAN NAPROXEN IN THE RAT REFEEDING MODELOrg: University of Calgary, AstraZeneca R and D,
Abstract
ASSOCIATION OF LUNG IMAGING PATTERN WITH PROGNOSIS AND IMMUNOSUPPRESSION RESPONSE IN CONNECTIVE TISSUE DISEASE ASSOCIATED INTERSTITIAL LUNG DISEASEOrg: McGill University Health Center, Saint James Hospital, McMaster University and Juravinski Cancer Centre, University of Montreal, University of Calgary,
Abstract
ANTIBODY CLUSTERING IN PEDIATRIC SYSTEMIC LUPUS ERYTHEMATOSUSOrg: Hospital for Sick Children, University of Toronto, Department of Biochemistry & Molecular Biology, University of Calgary,