Risk Stratification of Sudden Unexpected Death in Infant Based on Biomarkers - Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome

RC23_0260

This is a multicenter genetic study aimed at identifying new genes/variants associated with sudden infant death syndrome (SIDS) based on whole-genome sequencing of family trios

2024-02-01

2026-02-01

2027-04-01

Not yet recruiting

650

Child Inclusion Criteria * Death of a child between 0 and 2 years of age due to sudden unexpected death in infant * Child included in the French SUDI registry with effective participation in the biocollection * Children who also meet the inclusion criteria for the BIOMINRISK-NEUROBIO (axis 2) and BIOMINRISK-RADIO-ANAT (axis 3) studies in the overall BIOMINRISK project. Parents Inclusion Criteria * Biological parents of the child included in the BIOMINRISK study * Parents who have both signed the consent form for blood collection and inclusion of their samples in the biocollection * parents beneficiaries of a social security or similar scheme Child Exclusion Criteria: * Presence of a known metabolic, genetic or syndromic pathology at the time of death Parents Exclusion Crtiteria: * Parent under guardianship * Presence of a known metabolic, genetic or syndromic pathology

{'studyType': 'OBSERVATIONAL', 'patientRegistry': False, 'designInfo': {'observationalModel': 'FAMILY_BASED', 'timePerspective': 'CROSS_SECTIONAL'}, 'bioSpec': {'retention': 'SAMPLES_WITH_DNA', 'description': 'blood and DNA samples'}, 'enrollmentInfo': {'count': 650, 'type': 'ESTIMATED'}}

2024-02-06