Docetaxel
Aliases
Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, Chemo (55 other aliases)
348 clinical trials
81 products
10 abstracts
481 indications
Indication
Prostate CancerIndication
Breast CancerIndication
Breast NeoplasmsIndication
Breast Cancer (HER2-positive)Indication
Stage I Gastric Cancer AJCC v8Indication
Gastroesophageal Junction AdenocarcinomaIndication
Stage III Gastric CancerIndication
Gastric Cancer AJCC v8Indication
Stomach AdenocarcinomaIndication
Esophageal CancerIndication
Head and Neck CancerIndication
Brain CancerIndication
Neck CancerIndication
Head and Neck Squamous Cell CarcinomaIndication
HNSCCIndication
Stage II Breast CancerIndication
Triple-Negative Breast CarcinomaIndication
Head and NeckIndication
Squamous Cell Carcinoma of Head and NeckIndication
Lung Non-Small Cell CarcinomaIndication
Stage III Lung Cancer AJCC v8Indication
Stage IIIA Lung CancerIndication
Stage IIIB Lung CancerIndication
Lung CancerIndication
Stage IV Lung CancerIndication
Lung Cancer Stage IVA AJCC v8Indication
Advanced Solid TumorIndication
Metastatic Solid TumorIndication
Esophageal adenocarcinomaIndication
Metastatic Non-Small Lung Cell CancerIndication
Recurrent Non-Small Cell Lung CancerIndication
Esophageal squamous cell carcinomaIndication
BRCA1 MutationIndication
Metastatic Bladder Urothelial CarcinomaIndication
Renal Pelvis Urothelial CarcinomaIndication
Ureter Urothelial CarcinomaIndication
Urethral Urothelial CarcinomaIndication
Metastatic Urothelial CarcinomaIndication
Urothelial CarcinomaIndication
Refractory Ureter Urothelial CarcinomaIndication
Stage IV Bladder CancerIndication
Stage IV Renal Pelvis CancerIndication
Stage IV Ureter Cancer AJCC v8Indication
Urethral CancerIndication
Bladder Cancer, Stage IVA (AJCC v8)Indication
Bladder CancerIndication
Colorectal cancerIndication
Liver MetastasisIndication
Colorectal CancerIndication
Head and Neck CarcinomaIndication
Stomach CancerIndication
Castration-Resistant Prostate CarcinomaIndication
Bladder Urothelial CarcinomaIndication
Metastatic Non Small Cell Lung CancerIndication
Triple-Negative Breast CancerIndication
Oral Squamous Cell CarcinomaIndication
Neoadjuvant TherapyIndication
PD-1Indication
ChemotherapyIndication
Stage IIB Breast CancerIndication
Breast Cancer, Stage IVIndication
HER2-Positive Breast CarcinomaIndication
Breast CarcinomaIndication
Stage IIA Breast CancerIndication
Stage IIIA Breast CancerIndication
Stage IIIB Breast CancerIndication
Stage IV Breast Cancer AJCC v8Indication
Castration-resistant Prostate CancerIndication
Soft Tissue SarcomaIndication
OropharynxIndication
Human PapillomavirusIndication
Drug TherapyIndication
Cancer VaccineIndication
Gastric AdenocarcinomaIndication
Peritoneal CarcinomatosisIndication
Pancreatic CancerIndication
Liver MetastasesIndication
Prostate AdenocarcinomaIndication
CancerIndication
Prostate cancerIndication
Low-riskIndication
Esophageal cancerIndication
Recurrent Lung Non-Small Cell CarcinomaIndication
Triple-negative Breast CancerIndication
Squamous Cell CarcinomaIndication
OsteosarcomaIndication
cancerIndication
Squamous CellIndication
AdenocarcinomaIndication
Recurrent Acute Myeloid LeukemiaIndication
Recurrent B Acute Lymphoblastic LeukemiaIndication
Recurrent Mixed Phenotype Acute LeukemiaIndication
Recurrent T Acute Lymphoblastic LeukemiaIndication
Acute Myeloid LeukemiaIndication
Mixed Phenotype Acute LeukemiaIndication
Acute Lymphoblastic LeukemiaIndication
Rheumatoid ArthritisIndication
Esophageal Adenocarcinoma AJCC v8Indication
Esophageal Squamous Cell CarcinomaIndication
Oropharyngeal CancerIndication
Tonsil cancerIndication
throat cancerIndication
Tongue Squamous Cell CarcinomaIndication
Gastric Esophageal CancerIndication
RadiotherapyIndication
Recurrent Non-Small Cell Lung CarcinomaIndication
Stage IV Non-Small Cell Lung CancerIndication
Oligometastatic DiseaseIndication
Gastric Cancer, Stage IIIBIndication
Gastric Cancer Stage IIICIndication
lung cancerIndication
Non-small Cell Lung Cancer MetastaticIndication
Non-small Cell Lung Cancer Stage IIIBIndication
EGFR Negative Non-Small Cell Lung CancerIndication
ATM Gene MutationIndication
BRCA1 Gene MutationIndication
BRCA2Indication
Castration Levels of TestosteroneIndication
Ankylosing spondylitisIndication
Oral Cavity Squamous Cell CarcinomaIndication
Clear Cell AdenocarcinomaIndication
Ovarian Clear Cell AdenocarcinomaIndication
Endometrioid AdenocarcinomaIndication
Ovarian Serous AdenocarcinomaIndication
Mucinous AdenocarcinomaIndication
Brenner TumorIndication
Ovarian Clear Cell AdenocarcinofibromaIndication
Ovarian clear cell adenocarcinomaIndication
Endometrioid ovarian adenocarcinomaIndication
Ovarian Seromucinous CarcinomaIndication
Ovarian Transitional Cell CarcinomaIndication
Ovarian Undifferentiated CarcinomaIndication
Primary Peritoneal Serous AdenocarcinomaIndication
Recurrent Fallopian Tube CarcinomaIndication
Recurrent Ovarian CarcinomaIndication
Recurrent Primary Peritoneal CarcinomaIndication
Rectal CancerIndication
Malignant NeoplasmIndication
Metastatic Malignant Solid NeoplasmIndication
HRDIndication
prostate-specific antigen progressionIndication
Prostate Cancer, Stage III AJCC v8Indication
Prostate Cancer Stage IIIB AJCC v8Indication
NeoplasmIndication
Breast Cancer AJCC Stage IAIndication
Childhood EpendymomaIndication
Esophageal AdenocarcinomaIndication
Solid TumorIndication
AdultIndication
RetinoblastomaIndication
Drug EffectIndication
Primary Central Nervous System LymphomaIndication
Juvenile Idiopathic ArthritisIndication
Recurrent Non-small Cell Lung CancerIndication
MRDIndication
Genetic AbnormalityIndication
Non-Hodgkin lymphomaIndication
Chemotherapy ToxicityIndication
Uterine SarcomaIndication
Uterine Corpus LeiomyosarcomaIndication
Lymphoblastic LymphomaIndication
Breast Neoplasm FemaleIndication
Bladder AdenocarcinomaIndication
Bladder mixed adenocarcinomaIndication
Small Cell Lung CancerIndication
Small Cell Lung CarcinomaIndication
Thymic Epithelial TumorIndication
Thymic CarcinomaIndication
Thymic CancerIndication
Locally Advanced OperableIndication
PCNSLIndication
Bladder Squamous Cell CarcinomaIndication
Clear Cell VariantIndication
Micropapillary VariantIndication
Nested VariantIndication
plasmacytoid variantIndication
Atopic DermatitisIndication
Hematopoietic and Lymphoid Cell NeoplasmIndication
Stomach NeoplasmIndication
Gastrointestinal CancerIndication
Deleterious HRR Gene MutationIndication
BRIP1 Gene MutationIndication
CHEK2 mutationIndication
Fanconi anemiaIndication
PALB2 Gene MutationIndication
RAD51BIndication
RAD54L Gene MutationIndication
Chemotherapy EffectIndication
Predictive Cancer ModelIndication
Adult Lymphoblastic LymphomaIndication
Mucous Membrane PemphigoidIndication
Cicatrizing ConjunctivitisIndication
Biochemical RecurrenceIndication
Esophageal Adenocarcinoma Stage IIIAIndication
Alopecia AreataIndication
Recurrent B Lymphoblastic LymphomaIndication
B Lymphoblastic LymphomaIndication
Breast AdenocarcinomaIndication
HER2-positive breast carcinomaIndication
Stage III Breast CancerIndication
Breast cancerIndication
Psoriatic ArthritisIndication
PsoriasisIndication
lymphomaIndication
Myelodysplastic SyndromeIndication
Pediatric Solid TumorIndication
Chemotherapeutic Agent ToxicityIndication
Cognitive/Functional EffectsIndication
NeurotoxicityIndication
Radiation ToxicityIndication
Down syndromeIndication
Non-muscle-invasive Bladder CancerIndication
Gestational Trophoblastic TumorIndication
Gestational Trophoblastic NeoplasiaIndication
Invasive MoleIndication
ChoriocarcinomaIndication
Neoadjuvant ChemotherapyIndication
Testicular NeoplasmsIndication
Acute Lymphoblastic LymphomaIndication
Stage IIndication
Stage IIIndication
Acute Leukemia of Ambiguous LineageIndication
SarcomaIndication
LeukemiaIndication
Diffuse Large B-cell LymphomaIndication
Mantle Cell LymphomaIndication
Malignant Fibrous Histiocytoma of BoneIndication
ArthritisIndication
OncologyIndication
Endometrial CancerIndication
Advanced CancerIndication
Recurrent CancerIndication
Metastatic CancerIndication
Cardiac SarcoidosisIndication
SarcoidosisIndication
Oesophago-Gastric CarcinomaIndication
GliomaIndication
Pediatric Brain TumorIndication
Optic nerve gliomaIndication
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From Acute Leukemia of Ambiguous LineageIndication
Recurrent Acute Myeloid Leukemia Due to Lineage Switch From B Acute Lymphoblastic LeukemiaIndication
KMT2A RearrangedIndication
Refractory Acute Myeloid Leukemia Due to Lineage Switch From Mixed Phenotype Acute LeukemiaIndication
Hypopharyngeal carcinomaIndication
ImmunotherapyIndication
Recurrent/Advanced Gastric CancerIndication
Ph-Like Acute Lymphoblastic LeukemiaIndication
Primary central nervous system lymphomaIndication
HPVIndication
Oropharyngeal Squamous Cell CarcinomaIndication
Prostate Cancer Metastatic to BoneIndication
OligometastasisIndication
Bone Marrow MetastasisIndication
Disseminated Intravascular CoagulationIndication
B-cell Acute Lymphoblastic LeukemiaIndication
Neuroendocrine CarcinomaIndication
Non-Small Cell LungIndication
Ectopic PregnancyIndication
HER2-positive early breast cancerIndication
Follicular LymphomaIndication
VitiligoIndication
Recurrent Squamous Cell Lung CarcinomaIndication
Castration-Resistant Prostate CancerIndication
Advanced Soft Tissue SarcomaIndication
Undifferentiated Pleomorphic SarcomaIndication
MyxofibrosarcomaIndication
RheumatoidIndication
Osteoarthritis, KneeIndication
Synovial EffusionIndication
Knee PainIndication
hematologic malignanciesIndication
Diffuse Large B-Cell LymphomaIndication
High-Grade B-Cell LymphomaIndication
NSCLCIndication
Malignant NeoplasmsIndication
MelanomaIndication
Hodgkin lymphomaIndication
Renal Cell CarcinomaIndication
Subungual Squamous Cell CarcinomaIndication
Esophageal CarcinomaIndication
MSI-H Colorectal CancerIndication
Pleural mesotheliomaIndication
Brain and Central Nervous System TumorsIndication
Pancreatic adenocarcinomaIndication
Pancreatic Ductal AdenocarcinomaIndication
Pancreatic Cancer (Stage I)Indication
Colorectal AdenocarcinomaIndication
Colorectal Cancer stage IV AJCC v8Indication
Stage IVA Colorectal Cancer AJCC v8Indication
Stage IVB Colorectal Cancer AJCC v8Indication
Stage IVC Colorectal Cancer AJCC v8Indication
MesotheliomaIndication
Acute Lymphocytic LeukemiaIndication
Interstitial Lung DiseaseIndication
Angioimmunoblastic T-cell LymphomaIndication
Locally Advanced Breast CancerIndication
Pediatric Crohn's DiseaseIndication
Erythema Nodosum LeprosumIndication
Gastric CancerIndication
Adjuvant TherapyIndication
Ewing sarcomaIndication
RhabdomyosarcomaIndication
Myelodysplastic SyndromesIndication
Chronic Myeloid LeukemiaIndication
Chronic Lymphocytic LeukemiaIndication
Myeloproliferative DisordersIndication
Non-Hodgkin's LymphomaIndication
Multiple MyelomaIndication
Enteropathy-Associated T-Cell LymphomaIndication
Follicular T-Cell LymphomaIndication
Peripheral T-Cell LymphomaIndication
NOSIndication
Breast Cancer MetastaticIndication
Unresectable Sinonasal TumorsIndication
Sinonasal TumorsIndication
B-cell LymphomaIndication
Burkitt lymphomaIndication
Breast Cancer Stage IIIndication
Breast Cancer Stage IIIIndication
Hematopoietic Stem Cell TransplantationIndication
Langerhans Cell HistiocytosisIndication
Microbial ColonizationIndication
T-cell non-Hodgkin lymphomaIndication
Aplastic AnemiaIndication
Proliferative VitreoretinopathyIndication
Sinonasal CarcinomaIndication
Non-Hodgkin LymphomaIndication
Crohn's DiseaseIndication
AzathioprineIndication
MethotrexateIndication
Graft-Versus-Host DiseaseIndication
Cervical CancerIndication
Renal CellIndication
Ovarian CancerIndication
Nasopharyngeal CarcinomaIndication
Esophagogastric junctionIndication
T Lymphoblastic LymphomaIndication
PulmonaryIndication
AcuteIndication
ChildhoodIndication
Peripheral T-cell LymphomaIndication
Previously IrradiatedIndication
Liver ToxicityIndication
Chemically InducedIndication
KRAS Gene MutationIndication
LaryngocarcinomaIndication
JuvenileIndication
Testicular CancerIndication
BCR-ABL1 Fusion Protein ExpressionIndication
Blast Phase Chronic Myelogenous LeukemiaIndication
BCR-ABL1-positiveIndication
Philadelphia Chromosome PositiveIndication
t(9;22)Indication
lymphoproliferative disorderIndication
HHV-8Indication
HIVIndication
Brain MetastasesIndication
Metastatic Hormone-Naive Prostate CancerIndication
MucositisIndication
Oral ComplicationsIndication
Anus NeoplasmsIndication
Salivary Gland CarcinomaIndication
Recurrent Salivary Gland CarcinomaIndication
Bone SarcomaIndication
Non-Small Cell Lung Cancer Stage IVIndication
GlioblastomaIndication
Glioblastoma MultiformeIndication
IDH-wildtypeIndication
Brain cancerIndication
Non-Small Cell Lung Cancer Stage IIIBIndication
Non-Small Cell Lung Cancer Stage IIICIndication
HER2/Neu PositiveIndication
Progesterone Receptor PositiveIndication
Breast Cancer Stage IB AJCC v7Indication
Breast Cancer, Stage IIAIndication
AIDS-Related Anal CarcinomaIndication
Basaloid Squamous Cell CarcinomaIndication
Anal Canal Cloacogenic CarcinomaIndication
Anal Margin Squamous Cell CarcinomaIndication
Anal Squamous Cell CarcinomaIndication
HIV InfectionIndication
Rectal Squamous Cell CarcinomaIndication
Anal Cancer Stage I (AJCC v8)Indication
Anal CancerIndication
Rectal cancerIndication
Glottic Web of LarynxIndication
Laryngeal StenosisIndication
Laryngeal CancerIndication
Laryngeal LeukoplakiaIndication
Laryngeal PolypIndication
Laryngeal PapillomaIndication
Ewing SarcomaIndication
Bone MetastasisIndication
Pediatric CancerIndication
Nasal CavityIndication
Paranasal SinusesIndication
Sickle Cell DiseaseIndication
Transurethral ResectionIndication
EpendymomaIndication
MedulloblastomaIndication
Central Nervous System MalignanciesIndication
HR+/HER2- Breast CancerIndication
Metastatic TumorIndication
Non-Small Cell Lung CancerIndication
Chronic Actinic DermatitisClinical trial
Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate CancerStatus: Completed, Estimated PCD: 2008-02-01
Clinical trial
A Combined Phase I/II Feasibility-and-Efficacy Study of a Carbohydrate Mimotope-based Vaccine With MONTANIDE™ ISA 51 VG Combined With Neoadjuvant ChemotherapyStatus: Completed, Estimated PCD: 2023-01-03
Clinical trial
A Randomised, Phase 3 Trial Comparing 3-weekly Docetaxel 75 mg/m2 (in a 3 Week Cycle) Versus 2-weekly Docetaxel 50 mg/m2 (in a 4 Week Cycle) in Combination With Darolutamide + ADT in Patients With mHSPCStatus: Recruiting, Estimated PCD: 2025-02-01
Clinical trial
A Phase II, Open-label, Platform Study, to Evaluate Immunotherapy-based Combinations in Participants With Advanced Non-Small Cell Lung CancerStatus: Recruiting, Estimated PCD: 2026-09-01
Clinical trial
A Phase 2, Open-label, Randomized, Multi-arm Study of BGB-A445 in Combination With Investigational Agents in Non-Small Cell Lung Cancer Patients Previously Treated With Anti-PD-(L)1 AntibodyStatus: Recruiting, Estimated PCD: 2026-01-01
Abstract
Cabazitaxel with abiraterone versus abiraterone alone randomized trial for extensive disease following docetaxel: The CHAARTED2 trial of the ECOG-ACRIN Cancer Research Group (EA8153).Org: University of Wisconsin Carbone Cancer Center, Madison, WI, Dana-Farber Cancer Institute, Boston, MA, University of Wisconsin,
Clinical trial
BRE-10: BIomarker OptimizatioN of NeOadjuVAnt Therapy in BrEast Cancer: The INNOVATE TrialStatus: Recruiting, Estimated PCD: 2028-06-01
Clinical trial
A Randomized Phase II Study of Perioperative Atezolizumab +/- Chemotherapy in Resectable MSI-H/dMMR Gastric and Gastroesophageal Junction (GEJ) CancerStatus: Recruiting, Estimated PCD: 2027-10-31
Clinical trial
A Pilot Study of Neoadjuvant Cemiplimab With Platinum-Doublet Chemotherapy, and Cetuximab in Patients With Resectable, Locally Advanced Head and Neck Squamous Cell CarcinomaStatus: Recruiting, Estimated PCD: 2026-06-20
Clinical trial
Shorter Anthracycline-Free Chemo Immunotherapy Adapted to Pathological Response in Early Triple Negative Breast Cancer (SCARLET), A Randomized Phase III StudyStatus: Recruiting, Estimated PCD: 2033-03-31
Clinical trial
A Prospective, Multi-cohort, Exploratory Phase II Study of Trilaciclib Combined With Standard Chemotherapy in The Adjuvant Treatment of Hormone Receptor (HR) Negative Breast CancerStatus: Recruiting, Estimated PCD: 2026-12-31
Clinical trial
DETECT V / CHEVENDO A Multicenter, Randomized Phase III Study to Compare Chemo- Versus Endocrine Therapy in Combination With Dual HER2-targeted Therapy of Herceptin® (Trastuzumab) and Perjeta® (Pertuzumab) Plus Kisqali® (Ribociclib) in Patients With HER2 Positive and Hormone-receptor Positive Metastatic Breast Cancer.Status: Active (not recruiting), Estimated PCD: 2025-01-31
Clinical trial
Phase II Trial of Magrolimab and Cetuximab With Pembrolizumab or Docetaxel for Recurrent/Metastatic Head Neck Squamous Cell CarcinomaStatus: , Estimated PCD: 2027-11-30
Clinical trial
A Randomized Phase III Trial Investigating Platinum and Taxane Chemotherapy in Metastatic Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response GenesStatus: Not yet recruiting, Estimated PCD: 2029-09-30
Clinical trial
Randomized Phase II Study of Standard Chemotherapy With Docetaxel With or Without Bintrafusp Alfa in Patients With Advanced NSCLC After Progressing on a Combination of Anti-PD-1/PD-L1 Agents and ChemotherapyStatus: Terminated, Estimated PCD: 2023-12-31
Clinical trial
A Phase 1, Multicenter, Open-label, Dose-escalation Study Evaluating the Safety and Tolerability of Intravenous KK2269 Monotherapy and Combination Therapy With Docetaxel in Adult Participants With Solid TumorsStatus: Recruiting, Estimated PCD: 2027-12-01
Clinical trial
A Phase 2 Study of Docetaxel, Ramucirumab, and Pembrolizumab for Patients With Metastatic or Recurrent Non-Small Cell Lung Cancer Who Progressed on Platinum-Doublet and PD-1/PD-L1 BlockadeStatus: Recruiting, Estimated PCD: 2025-06-30
Clinical trial
A Phase III Randomized Controlled Clinical Study Comparing BL-B01D1 With Docetaxel in Patients With Unresectable Locally Advanced or Metastatic EGFR Wild-type Non-small Cell Lung Cancer After Failure of Anti-PD-1/PD-L1 Monoclonal Antibodies and Platinum-based ChemotherapyStatus: Recruiting, Estimated PCD: 2026-05-01
Clinical trial
Randomized, Open Label, Multicentric Phase III Evaluating the Benefit of a Sequential Regimen Associating FEC 100 and Ixabepilone in Adjuvant Treatment of Non Metastatic, Poor Prognosis Breast Cancer Defined as Triple-negative Tumor [HER2 Negative - ER Negative - PR Negative] or [HER2 Negative and PR Negative] Tumor; in Node Positive or Node Negative Patients.Status: Completed, Estimated PCD: 2017-06-01
Clinical trial
A Prospective Study of Savolitinib Plus Docetaxel in Pretreated EGFR/ALK/ROS1/MET ex14m-wildtype Advanced NSCLC Patients With MET Overexpression (FirstMET)Status: Recruiting, Estimated PCD: 2027-08-31
Clinical trial
A Prospective, Single-armed Study to Evaluate the Efficacy and Safety of Neoadjuvant Pembrolizumab Plus Chemotherapy in Resectable Locally Advanced Esophageal Squamous Cell Carcinoma PatientsStatus: Completed, Estimated PCD: 2023-03-30
Clinical trial
Neoadjuvant Phase II Trial Combining [3 FEC 100 Followed by 3 Docetaxel Associated With Trastuzumab Plus Pertuzumab] or [6 Docetaxel, Carboplatin Associated With Trastuzumab Plus Pertuzumab] According to TOP2A Status in Patients With T1c Operable, HER2-positive Breast CancerStatus: Active (not recruiting), Estimated PCD: 2019-10-07
Clinical trial
Multicenter Phase III, Randomized Study to Evaluate Treatment Customized According to RAP80 and BRCA1 Assessment in Patients With Advanced Non-small-cell Lung CancerStatus: Terminated, Estimated PCD: 2015-04-01
Clinical trial
A Phase III Randomized Trial of Eribulin (NSC #707389) With Gemcitabine Versus Standard of Care (Physician's Choice) for Treatment of Metastatic Urothelial Carcinoma Refractory to, or Ineligible for, Anti PD1/PDL1 TherapyStatus: Recruiting, Estimated PCD: 2027-08-15
Clinical trial
Sequential Therapy With Induction TPN Followed by Nivolumab With Radiation in Locoregionally Advanced Laryngeal and Hypopharyngeal CancerStatus: Completed, Estimated PCD: 2022-10-31
Clinical trial
A Phase I Trial of Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer (CRPC)Status: Active (not recruiting), Estimated PCD: 2024-12-31
Clinical trial
Randomized Controlled Phase II Trial of Liver Resection Versus No Surgery in Patients With Liver and Unresectable Pulmonary Metastases From Colorectal CancerStatus: Active (not recruiting), Estimated PCD: 2025-12-31
Clinical trial
Immunomodulation of Pembrolizumab Plus Docetaxel for the Treatment of Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (HNSCC) After Platinum FailureStatus: Completed, Estimated PCD: 2021-12-01
Clinical trial
The Single-center Randomized Study "Comparison of Safety and Effectiveness of the First Line of Polychemotherapy and Polychemotherapy in Combination With PIPAC Sessions in Primary Gastric Cancer With Isolated Peritoneal Carcinomatosis.Status: Recruiting, Estimated PCD: 2026-01-19
Clinical trial
A Phase 2 Study of M6620 (VX-970, Berzosertib) in Combination With Carboplatin Compared With Docetaxel in Combination With Carboplatin in Metastatic Castration-Resistant Prostate CancerStatus: Active (not recruiting), Estimated PCD: 2024-12-31
Clinical trial
A Phase II Trial for the Use of Intravesical Gemcitabine and Docetaxel (GEMDOCE) in the Treatment of BCG naïve Non-muscle Invasive Urothelial Carcinoma of the BladderStatus: Active (not recruiting), Estimated PCD: 2022-10-04
Clinical trial
A Multicenter, Phase II, Open Label, Randomized Trial Evaluating the Efficacy of Tedopi Plus Docetaxel or Tedopi Plus Nivolumab as Second-line Therapy in Metastatic Non-small-cell Lung Cancer Progressing After First-line Chemo-immunotherapy (Combi-TED)Status: Recruiting, Estimated PCD: 2023-10-17
Clinical trial
Phase II Study of Docetaxel Chemotherapy With Pembrolizumab and Interleukin-12 Gene Therapy in Patients With Anthracycline- Refractory Triple Negative Breast Cancer (INTEGRAL)Status: , Estimated PCD: 2024-06-01
Clinical trial
A Pilot Study of Sequential ("First Strike, Second Strike") Therapies, Modeled on Evolutionary Dynamics of Anthropocene Extinctions, for Hormone Positive Metastatic Breast CancerStatus: Recruiting, Estimated PCD: 2027-04-01
Clinical trial
Randomized, Placebo-Controlled, Phase 2 Study Of Induction Chemotherapy With Cisplatin/Carboplatin, And Docetaxel With Or Without Erlotinib In Patients With Head And Neck Squamous Cell Carcinomas Amenable For Surgical ResectionStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
A Phase II Study of OSI-774 in Combination With Cisplatin and Docetaxel in Metastatic or Recurrent Head and Neck Squamous Cell CancerStatus: Active (not recruiting), Estimated PCD: 2025-06-30
Clinical trial
Neoadjuvant Toripalimab and Albumin Paclitaxel /Cisplatin Versus Docetaxel/ Cisplatin/ 5-fluorouracil (TPF) on Pathological Response in Patients With Locally Advanced and Resectable Oral Squamous Cell CarcinomaStatus: Recruiting, Estimated PCD: 2024-09-30
Clinical trial
A Phase 1B Trial Evaluating the Safety of Ribociclib, Tucatinib, and Trastuzumab in Patients With Metastatic, HER2+ Breast Cancer and a Multicenter, Randomized, Open-Label, Phase 2 Study of Preoperative Treatment With Ribociclib,Ttrastuzumab, Tucatinib, and Fulvestrant Versus Docetaxel, Carboplatin,Ttrastuzumab, and Pertuzumab in HR+/HER2+ Breast Cancer and Ribociclib, Trastuzumab, and Tucatinib Versus Docetaxel, Carboplatin, Trastuzumab, and Pertuzumab in Patients With HR-/HER2+ Breast CancerStatus: Recruiting, Estimated PCD: 2025-04-01
Clinical trial
A Randomized Trial of Trastuzumab Deruxtecan and Biology-Driven Selection of Neoadjuvant Treatment for HER2-positive Breast Cancer: ARIADNEStatus: Recruiting, Estimated PCD: 2027-04-30
Clinical trial
Prospective Biomarker Analysis of Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Undergoing Sequential Treatment With Docetaxel and EnzalutamideStatus: Active (not recruiting), Estimated PCD: 2024-03-01
Clinical trial
PhAse 1/2 StuDy of Modern ImmunotherApy in BCG-Unresponsive, BCG-RelaPsing, and High-Risk BCG-Naive Non-muscle Invasive UroThelial Carcinoma of the BLADDERStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
A Phase I/II Study of M9241 With Docetaxel and Abiraterone in Adults With Metastatic Castration Sensitive and M9241 With Docetaxel in Castration Resistant Prostate CancerStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
A Phase II Trial of ADI-PEG 20 in Combination With Gemcitabine and Docetaxel for the Treatment of Soft Tissue Sarcoma Osteosarcoma, Ewing's Sarcoma, and Small Cell Lung CancerStatus: Completed, Estimated PCD: 2022-07-08
Clinical trial
Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) CancerStatus: Recruiting, Estimated PCD: 2028-01-10
Clinical trial
A Multi-center, Non-randomized, Three-cohort, Phase II Trial of a Modified Triplet Combination of Docetaxel, Oxaliplatin and Fluorouracil for Gastric Cancer With Peritoneal Carcinomatosis and Inoperable Malignant Bowel ObstructionStatus: Recruiting, Estimated PCD: 2026-12-31
Clinical trial
Neoadjuvant TIL- and Response-Adapted Chemoimmunotherapy for TNBCStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
EFFECT-neo: A Prospective, Open-label, Multicenter Phase III Study to Evaluate Efficacy and Safety of Pembrolizumab Combined With Standard Chemotherapy in the Neoadjuvant Treatment of Local Advanced (LA) HNSCCStatus: Recruiting, Estimated PCD: 2027-04-30
Clinical trial
A Feasibility Study of De-escalation of Chemotherapy in Patients With Early-Stage HER2 Positive Breast CancerStatus: , Estimated PCD: 2025-06-01
Clinical trial
Utility of Exosomal microRNAs to Predict Response to Androgen Deprivation Therapy in Prostate Cancer PatientsStatus: Active (not recruiting), Estimated PCD: 2021-05-11
Clinical trial
TreAtment Response and Omic-Markers in Triple-Negative Breast CAncer Patients Receiving Standard of Care Chemotherapy (TARMAC)Status: Not yet recruiting, Estimated PCD: 2029-06-01
Clinical trial
Phase 2 Randomized Trial of Standard of Care Chemotherapy With or Without Stereotactic Body Radiation Therapy for the Treatment of Oligometastatic Pancreatic AdenocarcinomaStatus: Recruiting, Estimated PCD: 2026-07-02
Clinical trial
A Randomized Clinical Trial Comparing Overall Survival in Selected Patients With ColoRectal Carcinoma Treated by Liver Transplantation or ChemotherapyStatus: Recruiting, Estimated PCD: 2027-01-01
Clinical trial
Effect of Chemotherapy Alone vs. Chemotherapy Followed by Surgical Resection on Survival and Quality of Life in Patients With Limited-metastatic Adenocarcinoma of the Stomach or Esophagogastric Junction - A Phase III Trial of Arbeitsgemeinschaft Internistische Onkologie/Chirurgische Arbeitsgemeinschaft Onkologie/Chirurgische Arbeitsgemeinschaft für Den Oberen Gastrointestinaltrakt (AIO/CAO-V/CAOGI)Status: Active (not recruiting), Estimated PCD: 2026-02-01
Clinical trial
SIMCAP (Surgery in Metastatic Carcinoma of Prostate): Phase 2.5 Multi-Institution Randomized Prospective Clinical Trial Evaluating the Impact of Cytoreductive Radical Prostatectomy Combined With Best Systemic Therapy on Oncologic and Quality of Life Outcomes in Men With Newly Diagnosed Metastatic Prostate CancerStatus: Recruiting, Estimated PCD: 2024-10-31
Clinical trial
Phase I, Open Label, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of the Combination RAD001 Plus Docetaxel in Patients With Metastatic Breast CancerStatus: Terminated, Estimated PCD: 2012-04-01
Clinical trial
A Phase 1, Three-Part, Open-Label, Parallel-Cohort Safety and Tolerability Study of Relugolix in Combination With Abiraterone Acetate Plus a Corticosteroid, Apalutamide, or Docetaxel With or Without Prednisone in Men With Metastatic Castration-Sensitive Prostate Cancer or Non-Metastatic or Metastatic Castration-Resistant Prostate CancerStatus: Active (not recruiting), Estimated PCD: 2024-05-29
Clinical trial
A Pilot Trial of Pembrolizumab Plus Chemoradiotherapy in Participants With Unresectable Gastroesophageal CancerStatus: Active (not recruiting), Estimated PCD: 2024-07-18
Clinical trial
Docetaxel and Prostvac for Metastatic Castration Sensitive Prostate CancerStatus: Active (not recruiting), Estimated PCD: 2022-07-01
Clinical trial
A Prospective, Multisite, Randomized, Open-label Phase III Clinical Trial (CLOVER Study)Comparing 4 Cycles With 6 Cycles of TC (Docetaxel+Cyclophosphamide) Adjuvant Chemotherapy for 1-3 Lymph Node Positive ER+/HER2- Early Breast CancerStatus: Recruiting, Estimated PCD: 2024-11-01
Clinical trial
A Multicentre Randomised Phase II Trial of Neo-adjuvant Chemotherapy Followed by Surgery vs. Neo-adjuvant Chemotherapy and Subsequent Chemoradiotherapy Followed by Surgery vs. Neo-adjuvant Chemoradiotherapy Followed by Surgery in Resectable Gastric CancerStatus: Active (not recruiting), Estimated PCD: 2025-04-01
Clinical trial
Precise Neoadjuvant Chemoresection of Low Grade NMIBC Guided by Drug Screens in Patient Derived Organoidst: A Single Center, Open-label, Phase II TrialStatus: Not yet recruiting, Estimated PCD: 2026-10-01
Clinical trial
A Phase III Clinical Trial of Docetaxel Plus Cisplatin Versus Vinorelbine Plus Cisplatin in Neoadjuvant Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma (NEOCRTEC308)Status: Active (not recruiting), Estimated PCD: 2025-07-01
Clinical trial
A Phase II Randomized Study of Ramucirumab Plus MK3475 (Pembrolizumab) Versus Standard of Care for Patients Previously Treated With Immunotherapy for Stage IV or Recurrent Non-Small Cell Lung Cancer (Lung-MAP Non-Matched Sub-Study)Status: Active (not recruiting), Estimated PCD: 2022-04-14
Clinical trial
An Open, Single-center, Phase II Trial of Cetuximab+Zimberelimab Combined With Platinum-containing Dual-agent Neoadjuvant Therapy for Locally Advanced Head and Neck Squamous Cell CarcinomaStatus: Not yet recruiting, Estimated PCD: 2024-11-01
Clinical trial
Phase 1/2 Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal CancerStatus: Completed, Estimated PCD: 2022-06-16
Clinical trial
Phase 1 Study of Cemiplimab - TP Induction Chemotherapy in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and NeckStatus: Recruiting, Estimated PCD: 2025-05-01
Clinical trial
Neoadjuvant Phase II Study of Pembrolizumab And Carboplatin Plus Docetaxel in Triple Negative Breast CancerStatus: Active (not recruiting), Estimated PCD: 2022-01-27
Clinical trial
A Salvage Trial of AR Inhibition With ADT and Apalutamide With Radiation Therapy Followed by Docetaxel in Men With PSA Recurrent Prostate Cancer After Radical Prostatectomy (STARTAR)Status: Completed, Estimated PCD: 2022-12-22
Clinical trial
A Randomized, Phase II Study of Definitive Radiotherapy With Concurrent Cisplatin vs. Docetaxel-cetuximab in Locally Advanced Head and Neck Squamous Cell Carcinoma: an ERCC1 Biomarker Enrichment and Interaction DesignStatus: Recruiting, Estimated PCD: 2030-12-01
Clinical trial
Phase 1 Trial of Dose Escalated BGB324 in Combination With Docetaxel for Previously Treated Advanced Non-small Cell Lung Cancer (NSCLC)Status: Completed, Estimated PCD: 2023-02-06
Clinical trial
A Phase 1/2 Study of Gemcitabine and Docetaxel in Combination With Hydroxychloroquine (Autophagy Inhibitor) in Patients With Recurrent OsteosarcomaStatus: Active (not recruiting), Estimated PCD: 2024-09-13
Clinical trial
National Lung Matrix Trial: Multi-drug, Genetic Marker-directed, Non-comparative, Multi-centre, Multi-arm Phase II Trial in Non-small Cell Lung CancerStatus: Active (not recruiting), Estimated PCD: 2024-09-01
Clinical trial
A Phase 1b Study of Combination of Avelumab and Taxane Based Chemotherapy in Platinum Refractory or Ineligible Metastatic Urothelial CancerStatus: Active (not recruiting), Estimated PCD: 2021-12-15
Clinical trial
A PedAL/EuPAL Phase 1/2 Trial of IMGN632 in Pediatric Patients With Relapsed or Refractory LeukemiaStatus: Withdrawn, Estimated PCD: 2023-09-01
Clinical trial
Efficacy, Tolerability and Preferences of Per Oral or Subcutaneous Methotrexate in Patients With Early Rheumatoid Arthritis - a Randomised Register Based Multicentre StudyStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
Phase II Trial of Pevonedistat (TAK-924) Plus Docetaxel in Patients With Previously Treated Advanced Non-Small Cell Lung CancerStatus: Terminated, Estimated PCD: 2021-11-04
Clinical trial
Phase II Study: Induction Chemotherapy Followed by Transoral Robotic Surgery and Neck Dissection for Definitive Management of Oropharyngeal Squamous Cell Carcinoma. (NECTORS Trial)Status: Recruiting, Estimated PCD: 2024-08-30
Clinical trial
Total Neoadjuvant Chemotherapy With 5-fluoruracil, Leucovorin, Oxaliplatin and Docetaxel in Locally Advanced Gastric and Gastroesophageal Junction Cancer (OCTASUR): Randomized, Single Center, Open Label Trial, Phase 2/3Status: Recruiting, Estimated PCD: 2027-12-01
Clinical trial
DART-HPV: A Phase III Evaluation of De-escalated Adjuvant Radiation Therapy for HPV-Associated Oropharynx CancerStatus: Active (not recruiting), Estimated PCD: 2022-08-20
Clinical trial
4CAST: A Phase 1b Dose Exploration and Dose Expansion, Open-label, Single-centre Study Evaluating the Safety and Efficacy of INO-464 in Combination With Chemotherapy in Patients With metASTatic Breast CancerStatus: Recruiting, Estimated PCD: 2024-07-01
Clinical trial
Consolidative Radiotherapy for Colorectal Cancer Liver Metastases Receiving Surgery or Radiofrequency AblationStatus: Withdrawn, Estimated PCD: 2021-06-01
Clinical trial
Maintenance Systemic Therapy Versus Local Consolidative Therapy (LCT) Plus Maintenance Systemic Therapy for Limited Metastatic Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II/III TrialStatus: Active (not recruiting), Estimated PCD: 2023-12-20
Clinical trial
Weekly Docetaxel, Cisplatin, and Cetuximab (TPC) in Palliative Treatment of Patients With SCCHNStatus: Completed, Estimated PCD: 2018-09-11
Clinical trial
A Prospective Randomised Phase III Study Of Androgen Deprivation Therapy With Or Without Docetaxel With Or Without Local Radiotherapy With Or Without Abiraterone Acetate And Prednisone In Patients With Metastatic Hormone-Naïve Prostate CancerStatus: Active (not recruiting), Estimated PCD: 2021-08-18
Clinical trial
Phase II Study for Curative Intent Treatment for Patients With Oligometastatic Disease at Initial PresentationStatus: Terminated, Estimated PCD: 2022-05-03
Clinical trial
Phase II, Open-label, Single-center Study Evaluating Safety and Activity of Androgen Deprivation Therapy Followed by Chemoimmunotherapy for Newly Metastatic Hormone-sensitive Prostate Cancer (mHSPC)Status: Active (not recruiting), Estimated PCD: 2024-03-01
Clinical trial
An Exploratory Study of the Safety and Efficacy of Genomic Biomarker-guided Neoadjuvant Therapy for Locally Advanced and Oligometastatic Prostate Cancer (SEGNO)Status: Recruiting, Estimated PCD: 2026-04-01
Clinical trial
A Randomized Phase II Study of ADT + Abiraterone Versus ADT + Docetaxel + Abiraterone in Patients With Low Volume Metastatic Hormone Sensitive Prostate CancerStatus: Active (not recruiting), Estimated PCD: 2024-05-03
Clinical trial
A Parallel Arm Phase 1b/2a Study of DKN-01 as Monotherapy or in Combination With Docetaxel for the Treatment of Advanced Prostate Cancer With Elevated DKK1Status: Terminated, Estimated PCD: 2022-07-19
Clinical trial
The Effect of Traditional Chinese Treatment Combined Adjuvant Chemotherapy in IIIb and IIIc Gastric Cancer: A Randomized Controlled TrialStatus: Completed, Estimated PCD: 2022-10-31
Clinical trial
Phase I Study of Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLCStatus: Active (not recruiting), Estimated PCD: 2025-04-01
Clinical trial
A Phase II/III Multicenter Study Evaluating the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Patients With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) Harboring Actionable Somatic Mutations Detected in Blood (B-FAST: Blood-First Assay Screening Trial)Status: Recruiting, Estimated PCD: 2028-08-03
Clinical trial
PLATI-PARP: A Phase 2 Study of Induction Docetaxel and Carboplatin Followed by Maintenance Rucaparib in Treatment of Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair DeficiencyStatus: Active (not recruiting), Estimated PCD: 2025-05-15
Clinical trial
Effect of Two Methotrexate Injections in Sync With the First Adalimumab Injection to Prevent the Immunisation Anti Adalimumab During Treatment of SpondyloarthritisStatus: Completed, Estimated PCD: 2022-09-13
Clinical trial
Postoperative Radiation and Concurrent Chemotherapy With Weekly Docetaxel Versus Cisplatin in Patients With High-risk Oral Cavity Cancer: a Randomized Phase II Clinical TrialStatus: Completed, Estimated PCD: 2022-02-28
Clinical trial
Prospective Validation Trial of Taxane Therapy (Docetaxel or Weekly Paclitaxel) and Risk of Chemotherapy-Induced Peripheral Neuropathy in African American WomenStatus: Active (not recruiting), Estimated PCD: 2024-06-30
Clinical trial
A Phase III Randomized Controlled Clinical Trial of Carboplatin and Paclitaxel (or Gemcitabine) Alone or in Combination With Bevacizumab (NSC #704865) Followed by Bevacizumab and Secondary Cytoreductive Surgery in Platinum-Sensitive, Recurrent Ovarian, Peritoneal Primary and Fallopian Tube Cancer. NCI-Supplied Agents: Bevacizumab (NSC #704865)Status: Active (not recruiting), Estimated PCD: 2019-04-30
Clinical trial
An International Clinical Program for the Diagnosis and Treatment of Children, Adolescents and Young Adults With EpendymomaStatus: Recruiting, Estimated PCD: 2028-06-01
Clinical trial
A Prospective, Single-arm, Phase II Clinical Trial to Evaluate the Efficacy and Safety of Tafolecimab and Sintilimab Combined With Chemotherapy in Patients With Advanced or Metastatic Driver Gene-negative Non-small Cell Lung Cancer After Failure of First-line Immunotherapy.Status: Recruiting, Estimated PCD: 2027-05-30
Clinical trial
Phase 2 Study of Total Neoadjuvant mFOLFOX and Short-Course Radiotherapy in Resectable Rectal CancerStatus: Recruiting, Estimated PCD: 2028-01-31
Clinical trial
A Phase I Study of AZD8186 in Combination With Docetaxel in Patients With PTEN Mutated or PIK3CB Mutated Advanced Solid Tumors, Potentially Amenable to DocetaxelStatus: Active (not recruiting), Estimated PCD: 2022-07-25
Clinical trial
A Phase II Trial of Atezolizumab Plus Chemotherapy After Progression on PD-1 or PD-L1 Inhibitor in Cisplatin-ineligible Patients With Advanced Urothelial Carcinoma: HCRN GU17-295Status: Terminated, Estimated PCD: 2022-03-08
Clinical trial
A Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of Second Mitochondrial-derived Activator of Caspases Mimetic BGB-24714 as Monotherapy and With Combination Therapies in Patients With Solid TumorsStatus: Recruiting, Estimated PCD: 2025-10-30
Clinical trial
Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary EnucleatedStatus: Recruiting, Estimated PCD: 2030-03-01
Clinical trial
Phase ll Trial of Docetaxel/Pembrolizumab Combination Treatment in Patients With Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaStatus: Recruiting, Estimated PCD: 2024-01-31
Clinical trial
Assessing the Efficacy and Safety of Optimal Neoadjuvant to Adjuvant Anti-HER2- Based Therapy in Nigerian Women With HER2+ Breast CancerStatus: Not yet recruiting, Estimated PCD: 2034-07-01
Clinical trial
A Randomized, Open Label, Multi-center Phase II-III Neoadjuvant Study Comparing the Efficacy and Safety of ARX788 Combined With Pyrotinib Maleate Versus TCBHP (Trastuzumab Plus Pertuzumab With Docetaxel and Carboplatin) in Patients With HER2-positive Breast CancerStatus: Active (not recruiting), Estimated PCD: 2025-12-30
Clinical trial
Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, Rituximab (TEDDI-R) in Primary CNS LymphomaStatus: Recruiting, Estimated PCD: 2025-06-15
Clinical trial
The Ondansetron Premedication Trial in Juvenile Idiopathic ArthritisStatus: Active (not recruiting), Estimated PCD: 2024-10-01
Clinical trial
A Multi-Center and Randomized Control Trial of Cisplatin, Carboplatin, Oxaliplatin, Docetaxel and Gemcitabine Plus Surgery as Treatment for Relapsed and Refractory Non-Small Cell Lung CancerStatus: Recruiting, Estimated PCD: 2026-12-01
Clinical trial
Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil - a Prospective Collaborative StudyStatus: Recruiting, Estimated PCD: 2028-06-01
Clinical trial
Tailoring NEOadjuvant Therapy in Hormone Receptor Positive, HER2 Negative, Luminal Breast Cancer.Status: Active (not recruiting), Estimated PCD: 2026-03-04
Clinical trial
Pilot-trial of Methotrexate, Tafasitamab (Minjuvi®), Lenalidomide (Revlimid®) and Rituximab in Patients Ineligible for HCT-ASCT With Primary Central Nervous System Lymphoma (PCNSL)Status: Not yet recruiting, Estimated PCD: 2027-02-01
Clinical trial
A Phase 2 Study of Preoperative Pembrolizumab and Chemotherapy Followed by Adjuvant Pembrolizumab in Resectable Locoregionally Recurrent Head and Neck Squamous Cell CarcinomaStatus: Recruiting, Estimated PCD: 2025-05-20
Clinical trial
A Pilot Safety and Toxicity Trial of Adjuvant Chemotherapy With Gemcitabine and Docetaxel and Radiation Therapy for Completely Resected Uterine LeiomyosarcomaStatus: Terminated, Estimated PCD: 2017-02-24
Clinical trial
Treatment Optimization in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment - a Phase IV-trial With a Phase III-part to Evaluate Safety and Efficacy of Nelarabine in T-ALL PatientsStatus: Active (not recruiting), Estimated PCD: 2022-08-01
Clinical trial
A Prospective, Open, Multicenter Single-arm Clinical Studie of Docetaxel, Carboplatin Combined With Inetetamab and Pyrotinib in the Treatment of Local-advanced HER2-positive Breast CancerStatus: Recruiting, Estimated PCD: 2025-07-31
Clinical trial
An Investigator-sponsored, Phase 1/2 Trial of the Oral XPO1 Inhibitor Selinexor (KPT-330) Monotherapy and in Combination With Docetaxel for Previously Treated, Advanced KRAS Mutant Non-small Cell Lung Cancer (NSCLC)Status: Completed, Estimated PCD: 2022-11-08
Clinical trial
Phase 2 Open Label Study of Durvalumab With Neoadjuvant Chemotherapy in Variant Histology Bladder CancerStatus: Terminated, Estimated PCD: 2022-08-11
Clinical trial
ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung CancersStatus: Recruiting, Estimated PCD: 2027-12-31
Clinical trial
Molecular Landscape Analysis and Treatment Options for Thymic Epithelial TumorsStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
An Open, Single-center, Phase II Trial of Cadonilimab Combined With Platinum-containing Dual-agent Neoadjuvant Therapy for Locally Advanced Operable Head and Neck Squamous Cell CarcinomaStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
Zanubrutinib Combined With Rituximab and Chemotherapy for Newly-Diagnosed Primary Central Nervous System Large B-Cell Lymphoma Patients Intolerant to Haematopoietic Stem Cell TransplantationStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
'Mind and Skin': A Prospective Cohort Study Evaluating the Impact of Inflammation, Itch and Sleep Disturbance on the Brain, Mental Health and Cognition, in Patients With Severe AtopyStatus: Recruiting, Estimated PCD: 2025-12-01
Clinical trial
Anti-CD22 Immunoconjugate Inotuzumab Ozogamicin (CMC-544) Added to Fludarabine, Bendamustine and Rituximab and Allogeneic Transplantation for CD22 Positive-Lymphoid MalignanciesStatus: Completed, Estimated PCD: 2023-06-28
Clinical trial
Preventive HIPEC in Combination With Perioperative FLOT Versus FLOT Alone for Resectable Diffuse Type Gastric and Gastroesophageal Junction Type II/III Adenocarcinoma - The Phase III "PREVENT" Trial of the AIO /CAOGI /ACOStatus: Recruiting, Estimated PCD: 2026-11-01
Clinical trial
Hispanic/Latino and Non-Hispanic BlAck Patients Treated With niRaparib and Abiraterone Acetate Plus Prednisone for Metastatic hOrmone Sensitive Prostate Cancer With Deleterious Homologous recombinatioN Repair Alterations: a Phase II, Open Label studYStatus: Not yet recruiting, Estimated PCD: 2027-04-01
Clinical trial
Postgenome-based Systemic Discovery of Strong Biomarkers Predict Gastric Cancer Chemotherapy ResponseStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
Phase Ib/II Study of the Combination of Low-Intensity Chemotherapy and Tagraxofusp in Patients With Acute Lymphoblastic Leukemia (ALL)Status: Recruiting, Estimated PCD: 2025-07-01
Clinical trial
Phase III Randomized Trial of Proton Beam Therapy (PBT) Versus Intensity Modulated Photon Radiotherapy (IMRT) for the Treatment of Esophageal CancerStatus: Recruiting, Estimated PCD: 2026-12-21
Clinical trial
Baricitinib for the Treatment of Ocular Mucous Membrane PemphigoidStatus: Terminated, Estimated PCD: 2023-09-11
Clinical trial
Salvage Radiotherapy Combined With Androgen Deprivation Therapy (ADT) With or Without Rezvilutamide in the Treatment of Biochemical Recurrence After Radical Prostatectomy for Prostate Cancer: a Prospective, Multicenter, Randomized Controlled Clinical StudyStatus: Recruiting, Estimated PCD: 2028-03-01
Clinical trial
Treatment of High-Risk Prostate Cancer Guided by Novel Diagnostic Radio- and Molecular Tracers (THUNDER): A Two-part Phase 2/ 3 TrialStatus: Recruiting, Estimated PCD: 2030-07-31
Clinical trial
Phase 1/2 Study of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metastatic Pancreatic CancerStatus: Completed, Estimated PCD: 2019-06-01
Clinical trial
Methotrexate With Microneedling Versus Triamcinilone Acetonide With Microneedling in Treatment of Recalcitrant Alopecia AreataStatus: Not yet recruiting, Estimated PCD: 2024-03-01
Clinical trial
A Phase 2 Study of Inotuzumab Ozogamicin (NSC# 772518) in Children and Young Adults With Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)Status: Recruiting, Estimated PCD: 2026-03-31
Clinical trial
A Randomized, Double-Blind, Phase III Trial of Taxane/Trastuzumab/Pertuzumab With Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast CancerStatus: Active (not recruiting), Estimated PCD: 2024-04-30
Clinical trial
Clinical Effectiveness of Standard Step up Care (Methotrexate) Compared to Early Combination DMARD Therapy With Standard Step up Care Compared to Early Use of TNF Inhibitors With Standard Step up Care for the Treatment of Moderate to Severe Psoriatic Arthritis: a 3-arm Parallel Group Randomised Controlled Trial.Status: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
Multicenter Randomized Double Blind Controlled-study to Assess the Potential of Methotrexate Versus Placebo to Improve and Maintain Response to Anti TNF- Alpha Agents in Adult Patients With Moderate to Severe PsoriasisStatus: Active (not recruiting), Estimated PCD: 2023-01-10
Clinical trial
Histological Response Rate After Mastectomy and Immediate Breast Reconstruction at the End of Neoadjuvant Chemotherapy and RadiotherapyStatus: Active (not recruiting), Estimated PCD: 2021-03-29
Clinical trial
Phase II Study of Rituximab Given in Conjunction With Standard Chemotherapy in Primary Central Nervous System (CNS) LymphomaStatus: Terminated, Estimated PCD: 2015-07-01
Clinical trial
A Phase II Clinical Trial to Evaluate the Efficacy and Safety of BL-M07D1, BL-M07D1+Pertuzumab and BL-M07D1+Pertuzumab+Docetaxel as First-line Treatment in Patients With Unresectable Locally Advanced or Metastatic HER2-positive Breast CancerStatus: Not yet recruiting, Estimated PCD: 2026-06-01
Clinical trial
A Feasibility Trial of MLN4924 (Pevonedistat, TAK 924) Given in Combination With Azacitidine, Fludarabine, and Cytarabine, in Children, Adolescents, and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeStatus: Completed, Estimated PCD: 2021-09-30
Clinical trial
Phase I Dose Escalation and Pharmacokinetics Clinical Trial of Mitoxantrone Hydrochloride Liposome in Children With Relapsed and Refractory Lymphoma and Solid TumorsStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
Phase II Randomized Study of Rituximab, Methotrexate, Procarbazine, Vincristine, and Cytarabine With and Without Low-Dose Whole-Brain Radiotherapy for Primary Central Nervous System LymphomaStatus: Completed, Estimated PCD: 2020-03-19
Clinical trial
A Phase 2 Study of Blinatumomab (NSC# 765986) in Combination With Nivolumab (NSC # 748726), a Checkpoint Inhibitor of PD-1, in B-ALL Patients Aged >/= 1 to < 31 Years Old With First RelapseStatus: , Estimated PCD: 2028-06-30
Clinical trial
A Randomized Phase III Trial of Intravesical BCG veRsus Intravesical Docetaxel and GEmcitabine Treatment in BCG Naïve High Grade Non-Muscle Invasive Bladder Cancer (BRIDGE)Status: Recruiting, Estimated PCD: 2029-11-01
Clinical trial
A Prospective,Multicenter,Randomized Trial of Biweekly Single-dose Actinomycin-D Versus Multi-day Methotrexate Protocol for the Treatment of Low-risk Gestational Trophoblastic NeoplasiaStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
A Phase II Study of Induction Chemotherapy Followed by Surgical Treatment in Locally Advanced Oropharyngeal And Supraglotic Cell CarcinomaStatus: Active (not recruiting), Estimated PCD: 2023-12-30
Clinical trial
Perioperative Chemotherapy (FLOT Protocol) Compared To Neoadjuvant Chemoradiation (CROSS Protocol) in Patients With Adenocarcinoma of the EsophagusStatus: Active (not recruiting), Estimated PCD: 2024-05-01
Clinical trial
A Multi-center Randomized Phase II Study of Doxorubicin Liposome Versus Epirubicin Plus Cyclophosphamide Combined With Trastuzumab and Pertuzumab(HP), Followed by Taxon Plus HP as Neoadjuvant Therapy for HER2-positive Early Breast CancerStatus: Active (not recruiting), Estimated PCD: 2023-09-30
Clinical trial
GAMEC-SHORT (S) & GAMEC-ANTHRACYCLINE(A) (Combination Chemotherapy With GCSF, Actinomycin-D, Methotrexate, Etoposide and Cisplatin) Risk-adapted Protocol for Relapsed Germ Cell Tumours (GCT)Status: Completed, Estimated PCD: 2013-06-01
Clinical trial
A Phase II Study of Docetaxel Before Medical Castration With Degarelix in Patients With Newly Diagnosed Metastatic Prostatic Adenocarcinoma.Status: Active (not recruiting), Estimated PCD: 2024-05-31
Clinical trial
The Study of Envafolimab Plus Docetaxel in Combination With or Without Trilaciclib Versus Docetaxel in Advanced NSCLC Previously Treated With a PD-1 Inhibitor Combined With ChemotherapyStatus: Not yet recruiting, Estimated PCD: 2025-12-30
Clinical trial
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and LymphomaStatus: Active (not recruiting), Estimated PCD: 2026-09-30
Clinical trial
Predicting Esophageal Cancer Borders Using PET-Imaging PEGASUSStatus: Recruiting, Estimated PCD: 2026-01-01
Clinical trial
A Groupwide Pilot Study to Test the Tolerability and Biologic Activity of the Addition of Azacitidine (NSC# 102816) to Chemotherapy in Infants With Acute Lymphoblastic Leukemia (ALL) and KMT2A (MLL) Gene RearrangementStatus: Active (not recruiting), Estimated PCD: 2020-09-30
Clinical trial
Phase I/II Study of Gemcitabine and Docetaxel Combined With Immune Checkpoint Blockade (Retifanlimab) in Patients With Advanced Soft Tissue SarcomaStatus: Active (not recruiting), Estimated PCD: 2025-09-29
Clinical trial
Phase II Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic LeukemiaStatus: Recruiting, Estimated PCD: 2027-12-31
Clinical trial
A Clinical Study Was Conducted to Evaluate the Efficacy and Safety of the RCMOP Regimen Sequential Therapy as a First-line Treatment for Patients With Intermediate-to-high Risk Diffuse Large B-cell Lymphoma Who Had Incomplete Remission.Status: Not yet recruiting, Estimated PCD: 2024-08-01
Clinical trial
Ofatumumab (O) in Combination With Chemotherapy: Hyper-Fractionated Cyclophosphamide, Doxorubicin, Vincristine and Dexamethasone (O-HyperCVAD) Alternating With Ofatumumab High-Dose Cytarabine and Methotrexate (O-MA) for Patients With Newly Diagnosed Mantle Cell LymphomaStatus: Completed, Estimated PCD: 2018-04-26
Clinical trial
A Randomized, Open Labeled Phase II Pilot Study of Total Neoadjuvant Chemotherapy With FLOT ( FLOT-TNT) VS Standard Perioperative FLOT ( FLOTPOP) in Patients With Gastric or GEJ Cancer, and Assessment of CTDNA as Correlative Biological ResponseStatus: Recruiting, Estimated PCD: 2028-10-01
Clinical trial
First-line Anti-PD-1 Therapy Plus Chemotherapy With or Without Radiotherapy in Metastatic Esophageal Squamous Cell Carcinoma: A Phase II Multi-center, Randomized Trial (SCR-ESCC-01)Status: Recruiting, Estimated PCD: 2026-01-01
Clinical trial
A Study of Bevacizumab, a Humanized Monoclonal Antibody Against Vascular Endothelial Growth Factor (VEGF), in Combination With Chemotherapy for Treatment of OsteosarcomaStatus: Completed, Estimated PCD: 2014-08-01
Clinical trial
Methotrexate Treatment of Arthritis Caused by Chikungunya Virus (MARCH): A Phase III Randomized Controlled Clinical Trial of the Efficacy of Methotrexate Monotherapy in the Treatment of Chronic Arthritis After Chikungunya InfectionStatus: , Estimated PCD: 2027-08-30
Clinical trial
A Randomized Phase II Study of Reolysin in Patients With Previously Treated Advanced or Metastatic, Non Small Cell Lung Cancer Receiving Standard Salvage Therapy.Status: Completed, Estimated PCD: 2016-01-26
Clinical trial
Patients Characteristics, Treatment Pattern & Outcomes of Patients With Advanced, Recurrent or Metastatic Endometrial Carcinoma: A Retrospective StudyStatus: Completed, Estimated PCD: 2022-11-22
Clinical trial
Cardiac Sarcoidosis Multi-Center Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2025-12-01
Clinical trial
ESSAI DE PHASE III RANDOMISE EVALUANT LE FOLFOX AVEC OU SANS DOCETAXEL (TFOX) EN 1ère LIGNE DE CHIMIOTHERAPIE DES ADENOCARCINOMES OESO-GASTRIQUES LOCALEMENT AVANCES OU METASTATIQUESStatus: Active (not recruiting), Estimated PCD: 2023-04-01
Clinical trial
Clinical Study of Modified Carboplatin/Vincristine Chemotherapy Regimen for Visual Function Protection in Children With Optic Pathway GliomasStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
A Phase 2 Study of SNDX-5613 in Combination With Chemotherapy for Patients With Relapsed or Refractory KMT2A-Rearranged Infant LeukemiaStatus: Recruiting, Estimated PCD: 2027-12-31
Clinical trial
A Phase II, Single-center, Open-label, Single-arm Study of Induction Chemotherapy Combined With Immunotherapy for Locally Advanced Hypopharyngeal CarcinomaStatus: Active (not recruiting), Estimated PCD: 2023-04-16
Clinical trial
An Open Label, Single-Arm, Multi-Center Phase II Study to Evaluate the Efficacy of Triplet Combination With Pembrolizumab, Neratinib, and Paclitaxel as a Second Line Treatment in Recurrent/Advanced Gastric Cancer Having Somatic Human Epidermal Growth Factor Receptor Family (EGFR, HER2, HER3, HER4) Mutations or HER2 Amplification/OverexpressionStatus: Withdrawn, Estimated PCD: 2023-10-30
Clinical trial
A Phase 1 Study Combining Venetoclax With a Pediatric-Inspired Regimen for Newly Diagnosed Adults With B Cell Ph-Like Acute Lymphoblastic LeukemiaStatus: Recruiting, Estimated PCD: 2024-05-22
Clinical trial
Selinexor in Combination With Methotrexate and Rituximab for Relapsed /Refractory Central Nervous System (CNS) LymphomaStatus: Recruiting, Estimated PCD: 2026-06-30
Clinical trial
Phase II Evaluation of Adjuvant Hyperfractionated Radiation and Docetaxel for HPV Associated Oropharynx CancerStatus: Completed, Estimated PCD: 2016-10-20
Clinical trial
Outcomes of Local Treatment for Oligometastatic Prostate Cancer Diagnosed Using PSMA PET Imaging: OLIGOMET StudyStatus: Not yet recruiting, Estimated PCD: 2031-01-01
Clinical trial
Infusional Fluorouracil and Weekly Docetaxel as First-line Therapy for Gastric Cancer With Bone Marrow Metastasis and Disseminated Intravascular Coagulation: a Multi-center, Phase II TrailStatus: Completed, Estimated PCD: 2024-02-25
Clinical trial
Phase I Study of Inotuzumab Ozogamicin With 3 and 4 Drug Augmented Berlin-Frankfurt-Münster (BFM) Re-Induction for Patients With Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia (B-ALL)Status: Active (not recruiting), Estimated PCD: 2023-07-15
Clinical trial
A Multi-centre, Randomised, Parallel Group, Open-label, Phase II, Single-stage Selection Trial of Liposomal Irinotecan (Nal-IRI) and 5-fluorouracil (5-FU)/Folinic Acid or Docetaxel as Second-line Therapy in Patients With Progressive Poorly Differentiated Extra-pulmonary Neuroendocrine Carcinoma (NEC))Status: Active (not recruiting), Estimated PCD: 2023-12-01
Clinical trial
A Prospective Randomized Controlled Study Comparing the Efficacy and Safety of Rezvilutamide+ADT+Docetaxel Versus Rezvilutamide +ADT in the Treatment of Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)Status: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating The Efficacy And Safety Of Multiple Immunotherapy-Based Treatment Combinations In Patients With Metastatic Non-Small Cell Lung Cancer (Morpheus-Lung)Status: Active (not recruiting), Estimated PCD: 2025-09-30
Clinical trial
A Phase II Study of Initial Treatment With Methotrexate in Large Granular Lymphocytic (LGL) LeukemiaStatus: Terminated, Estimated PCD: 2010-12-01
Clinical trial
Use of Letrozole in the Treatment of Early Ectopic PregnancyStatus: Recruiting, Estimated PCD: 2026-12-31
Clinical trial
Phase II Study of Rituximab in Combination With Methotrexate, Doxorubicin, Cyclophosphamide, Leucovorin, Vincristine, Ifosfamide, Etoposide, Cytarabine and Mesna (R-MACLO/VAM) in Patients With Previously Untreated Mantle Cell LymphomaStatus: Active (not recruiting), Estimated PCD: 2024-09-01
Clinical trial
A Randomized Controlled, Phase III Trial in HER2-positive Lymph Node Positive Early Breast Cancer to Compare the Efficacy and Safety of Epriubin Plus Cyclophosphamide Followed by Docetaxel Plus Trastuzumab and Pertuzumab (EC-THP) Versus Docetaxel and Carboplatin Plus Trastuzumab and Pertuzumab (TCbHP) in the Adjuvant TreatmentStatus: Recruiting, Estimated PCD: 2031-07-01
Clinical trial
A Real-world Study of the Efficacy and Safety of Obinutuzumab-based Therapy for Previously Untreated Follicular LymphomaStatus: Recruiting, Estimated PCD: 2025-06-30
Clinical trial
A Single Arm, Multi-center, Phase II Clinical Trial of Rituximab, Lenalidomide Combined With High-dose Methotrexate and Temozolomide (RL-MT) in the First-line Treatment for Patients With Primary Central Nervous System LymphomaStatus: Recruiting, Estimated PCD: 2024-01-13
Clinical trial
An International Phase II Trial Assessing Tolerability and Efficacy of Sequential Methotrexate-Aracytin-based Combination and R-ICE Combination, Followed by HD Chemotherapy Supported by ASCT, in Patients With Systemic B-cell Lymphoma With CNS Involvement at Diagnosis or Relapse (MARIETTA Regimen)Status: Active (not recruiting), Estimated PCD: 2019-08-01
Clinical trial
Efficacy and Tolerance of the Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo: a Randomized Double-blind Prospective StudyStatus: Recruiting, Estimated PCD: 2025-10-10
Clinical trial
Randomized, Multicentre Phase II Trial of the Sequencing of Radium-223 and Docetaxel Plus Prednisone in Symptomatic Bone-only Metastatic Castration-resistant Prostate Cancer (mCRPC)Status: Recruiting, Estimated PCD: 2025-07-01
Clinical trial
Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate CancerStatus: Recruiting, Estimated PCD: 2026-04-01
Clinical trial
Roflumilast Versus Methotrexate in the Treatment of PsoriasisStatus: Completed, Estimated PCD: 2023-05-09
Clinical trial
A Phase II Study of MEDI4736 for Previously Treated Patients With Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers (Lung-Map Sub-Study)Status: Completed, Estimated PCD: 2018-09-01
Clinical trial
Phase 2 Open Label Study of Pembrolizumab in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC) With or Without DNA Damage Repair DefectsStatus: Completed, Estimated PCD: 2023-09-28
Clinical trial
Induction by Docetaxel/Cisplatin/5-Fluorouracil (TCF) Prior to Radiotherapy With Concomintant Cetuximab in Locally Advanced Inoperable Head and Neck Tumours - a Methodical TrialStatus: Completed, Estimated PCD: 2010-01-19
Clinical trial
Brightline-3: A Phase III, Randomized, Open-label, Multi-center Trial of Brigimadlin + Ezabenlimab Compared to Gemcitabine + Docetaxel for Second-line Treatment of Patients With Advanced TP53 Wild-type Soft Tissue Sarcoma SubtypesStatus: Not yet recruiting, Estimated PCD: 2026-07-03
Clinical trial
A Phase II Study to Measure Response Rate and Toxicity of Neo-adjuvant Chemoradiotherapy With Oxaliplatin (OX) and Infusional 5-Fluorouracil (5-FU) Plus Cetuximab Followed by Post-Operative Docetaxel and Cetuximab in Patients With Operable Adenocarcinoma of the EsophagusStatus: Terminated, Estimated PCD: 2011-10-01
Clinical trial
The Efficacy and Safety of the Modified Zhiwang Decoction Combined With Methotrexate in Early Rheumatoid ArthritisStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
CADENCE: Carboplatin and Docetaxel in Neoadjuvant Treatment of ER-Negative, HER2-Negative Breast Cancer: A Co-Clinical Trial With Genoproteomic DiscoveryStatus: Active (not recruiting), Estimated PCD: 2019-06-25
Clinical trial
Pharmacokinetics and Pharmacogenetics-based Adaptive Dosing of 5-fu (5-Fluorouracile) in Head & Neck Cancer Patient Undergoing Docetaxel, Cisplatin, 5-Fluorouracile (=TPF) TherapyStatus: Completed, Estimated PCD: 2017-01-25
Clinical trial
A Randomized, Double-blind, Placebo-controlled Clinical Trial of Methotrexate (MTX) in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitisStatus: Completed, Estimated PCD: 2023-11-01
Clinical trial
A Feasibility Trial of Everolimus (RAD001),an mTOR Inhibitor, Given in Combination With Multiagent Re-Induction Chemotherapy in Pediatric Patients With Relapsed Acute Lymphoblastic Leukemia (ALL)Status: Completed, Estimated PCD: 2017-01-01
Clinical trial
Comparative Effectiveness Trial of Transoral Head and Neck Surgery Followed by Adjuvant Radio(Chemo)Therapy Versus Primary Radiochemotherapy for Oropharyngeal CancerStatus: Active (not recruiting), Estimated PCD: 2024-05-05
Clinical trial
PROACTIVE: Prevention of Acute and Chronic GVHD Using TocIlizumab in Combination With Standard GVHD Prophylaxis After allogEneic TransplantationStatus: Completed, Estimated PCD: 2022-03-02
Clinical trial
A Phase I-II Study of the Combination of Ruxolitinib or Dasatinib With Chemotherapy in Patients With Philadelphia Chromosome (Ph)-Like Acute Lymphoblastic Leukemia (ALL)Status: Terminated, Estimated PCD: 2021-01-20
Clinical trial
A Randomized, Open-label Phase II/III Efficacy and Safety Study of Atezolizumab in Combination With FLOT Versus FLOT Alone in Patients With Gastric Cancer and Adenocarcinoma of the Oesophago-gastric Junction and High Immune Responsiveness (MO30039/MO43340) - The DANTE TrialStatus: Recruiting, Estimated PCD: 2027-05-31
Clinical trial
Immunostart: Prephase Tafasitamab, Retifanlimab, and Rituximab (TRR), Followed by TRR With Standard Therapy for Previously Untreated Diffuse Large B-Cell LymphomaStatus: Recruiting, Estimated PCD: 2026-01-05
Clinical trial
A Phase III Randomized Trial of Steroids + Tyrosine Kinase Inhibitor (TKI) Induction With Chemotherapy or Blinatumomab for Newly Diagnosed BCR-ABL-Positive Acute Lymphoblastic Leukemia (ALL) in AdultsStatus: Recruiting, Estimated PCD: 2028-07-01
Clinical trial
A Phase II Study of Adjuvant Treatment With Cisplatin-based Chemotherapy Plus Concomitant Atezolizumab in Patients With Stage I (Tumors ≥ 4cm), IIA, IIB, and Select Stage III [Any T1-3 N1-2 and T4N0-2] Resected Non-small Cell Lung Cancer (NSCLC) and the Clearance of Circulating Tumor DNA (ctDNA) Big Ten Cancer Research Consortium BTCRC-LUN19-396Status: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
A Phase II/III Study of N-803 (ALT-803) Plus Pembrolizumab Versus Standard of Care in Participants With Stage IV or Recurrent Non-Small Cell Lung Cancer Previously Treated With Anti-PD-1 or Anti-PD-L1 Therapy (Lung-MAP Non-Match Sub-Study)Status: Active (not recruiting), Estimated PCD: 2027-02-01
Clinical trial
"A Randomized Multicenter Phase II Trial to Evaluate the Effectiveness of Selective Neoadjuvant Treatment According to Immunohistochemical Subtype for HER2 Negative Breast Cancer Patients"Status: Completed, Estimated PCD: 2010-09-01
Clinical trial
Efficacy and Toxicity of Docetaxel as a Radiosenstizer in Head and Neck CancerStatus: Not yet recruiting, Estimated PCD: 2025-06-01
Clinical trial
Phase III Randomized Comparing Docetaxel, Doxorubicin and Cyclophosphamide (TAC) vs 5-Fluorouracil, Doxorubicin and Cyclophosphamide (FAC) as Adjuvant Treatment of High Risk Operable Breast Cancer Patients With Negative Axillary Lymph NodesStatus: Completed, Estimated PCD: 2010-12-02
Clinical trial
A Phase Ib Dose Escalation, Open Label, Multicenter Study Evaluating LDE225 (Sonidegib) in Combination With Docetaxel in Triple Negative (TN) Advanced Breast Cancer (ABC) Patients "EDALINE"Status: Completed, Estimated PCD: 2016-04-01
Clinical trial
Phase II Trial of Response-Adapted Therapy Based on Positron Emission Tomography (PET) for Bulky Stage I and II Classical Hodgkin Lymphoma (HL)Status: Terminated, Estimated PCD: 2015-04-09
Clinical trial
Phase III Trial of Laryngeal Preservation Comparing Induction Chemotherapy With Cisplatin, 5-fluorouracil and Docetaxel (TPF) Followed by Radiotherapy and Concomitant Administration of Radiotherapy With CisplatinStatus: Active (not recruiting), Estimated PCD: 2028-10-01
Clinical trial
A Randomized Multicenter Phase III Trial Comparing Docetaxel or Hormone Therapy as Second Line Treatment in Patients With Asymptomatic or Oligosymptomatic Metastatic Castration-resistent Prostate Cancer (mCRPC) Progressing After Abiraterone or Enzalutamide.Status: Active (not recruiting), Estimated PCD: 2023-12-01
Clinical trial
A Phase Ib/II Open Label, Multi-arm, Parallel Cohort Dose Finding and Expansion Study to Assess the Safety, Pharmacokinetics and Efficacy of NUC-3373, a Nucleotide Analogue, Given in Combination With Standard Approved Agents in Patients With Advanced Solid TumoursStatus: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
Multiple-Arm Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of XmAb20717 in Combination With Standard of Care Treatment in Patients With Metastatic Castration Sensitive Prostate CancerStatus: Recruiting, Estimated PCD: 2026-12-16
Clinical trial
A Phase 2 Multicohort Study of Nivolumab in Combination With Docetaxel and Androgen Deprivation Therapy in Metastatic Hormone Sensitive Prostate Cancer Patients With DNA Damage Repair Defects or Inflamed TumorsStatus: Active (not recruiting), Estimated PCD: 2024-06-30
Clinical trial
Prospective Clinical Study to Observe the Efficacy and Safety of Tacrolimus in Refractory Rheumatoid Arthritis Patients for 6 Months Treatment in ChinaStatus: Completed, Estimated PCD: 2022-09-30
Clinical trial
A Multicenter, Double-blind, Randomized, Parallel-group, Phase III Study of the Efficacy and Safety of QL1701 Plus Docetaxel Versus Herceptin® Plus Docetaxel as First Line Therapy in Patients With HER2-positive Metastatic Breast CancerStatus: Completed, Estimated PCD: 2022-12-31
Clinical trial
A Phase 1/1b Study to Evaluate the Safety and Tolerability of AB801 Monotherapy and Combination Therapy in Participants With Advanced MalignanciesStatus: Recruiting, Estimated PCD: 2026-11-01
Clinical trial
Phase III Trial to Compare Epirubicin and Cyclophosphamide (EC) Followed by Docetaxel (T) to Epirubicin and Docetaxel (ET) Followed by Capecitabine (X) as Adjuvant Treatment, Node Positive Breast Cancer PatientsStatus: Completed, Estimated PCD: 2013-06-01
Clinical trial
A Phase II Trial of Preradiation Multiagent Chemotherapy for Adults With "Poor Risk" Medulloblastoma, PNET, and Disseminated EpendymomaStatus: , Estimated PCD: 2004-03-01
Clinical trial
Comparison of With and Without Sequential Single Drug Therapy of S-1 After Adjuvant Chemotherapy With Docetaxel Plus S-1 in Stage III Gastric CancerStatus: Recruiting, Estimated PCD: 2026-12-31
Clinical trial
A Phase II-R and a Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (Ph III) as Adjuvant Treatment for Patients With Resected Head of Pancreas AdenocarcinomaStatus: Active (not recruiting), Estimated PCD: 2023-12-10
Clinical trial
A Randomized Phase II Trial of Cabozantinib and Cabozantinib Plus Nivolumab Versus Standard Chemotherapy in Patients With Previously Treated Non-Squamous NSCLCStatus: Active (not recruiting), Estimated PCD: 2024-09-30
Clinical trial
A Phase 1 Dose Escalation and Cohort Expansion Study of TSR-022, an Anti-TIM-3 Monoclonal Antibody, in Patients With Advanced Solid Tumors (AMBER)Status: Recruiting, Estimated PCD: 2025-04-09
Clinical trial
Durvalumab and Standard Chemotherapy for the Treatment of Lymph Node Positive Bladder CancerStatus: Recruiting, Estimated PCD: 2026-08-31
Clinical trial
The Role of Multimodality Management in Risk-Stratified Patients With Lung-Limited Metastatic Colorectal CancerStatus: Active (not recruiting), Estimated PCD: 2030-01-31
Clinical trial
GALLANT: A Phase 2 Study Using Metronomic Gemcitabine, Doxorubicin, Docetaxel and Nivolumab as Second/Third Line Therapy for Advanced SarcomaStatus: Recruiting, Estimated PCD: 2025-09-30
Clinical trial
Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic LeukemiaStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
Aggressive Multi-Modality Management of Malignant Pleural MesotheliomaStatus: Completed, Estimated PCD: 2009-06-01
Clinical trial
Pilot Study for Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic LeukemiaStatus: Completed, Estimated PCD: 2003-06-01
Clinical trial
Effects of Tofacitinib vs Methotrexate on Clinical and Molecular Disease Activity Markers in Joints and Lungs in Early Rheumatoid Arthritis (PULMORA) - A Randomized, Controlled, Open-label, Assessor-blinded, Phase IV TrialStatus: Terminated, Estimated PCD: 2023-11-30
Clinical trial
A Randomized Phase II Study of CHO(E)P vs CC-486-CHO(E)P vs Duvelisib-CHO(E)P in Previously Untreated CD30 Negative Peripheral T-Cell LymphomasStatus: Recruiting, Estimated PCD: 2025-06-30
Clinical trial
A Randomized, Open-label, Single-center, Phase III Trial Comparing Docetaxel Plus Carboplatin (TCb) Versus Epirubicin Plus Cyclophosphamide Followed by Docetaxel (EC-T) Regimen as Adjuvant Chemotherapy in Patients With LN≥4 Estrogen Receptor Positive and Human Epidermal Growth Factor Receptor 2 Negative (ER+/HER2-) Breast CancerStatus: Recruiting, Estimated PCD: 2026-06-01
Clinical trial
A Phase II Randomized Trial Evaluating Neoadjuvant Dose-Dense Doxorubicin/Cyclophosphamide Followed by Paclitaxel/Trastuzumab/Pertuzumab (AC THP) and Docetaxel/Carboplatin/Trastuzumab/Pertuzumab (TCHP) For Early Her2Neu Positive Breast CancerStatus: Terminated, Estimated PCD: 2021-03-07
Clinical trial
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Pragmatic Clinical Trial To Evaluate The Effectiveness Of Low Dose Oral Methotrexate In Patients With Pediatric Crohn's Disease Initiating Anti-TNF TherapyStatus: Completed, Estimated PCD: 2022-04-07
Clinical trial
A Randomized Controlled, Open-label, Multicenter Clinical Study of Pyrotinib Maleate Combined With Trastuzumab,Dalpiciclib, and Letrozole Versus Trastuzumab Combined With Pertuzumab, Docetaxel, and Carboplatin as Neoadjuvant Therapy for Stage II-III HR +/HER2 + Breast CancerStatus: Recruiting, Estimated PCD: 2025-12-10
Clinical trial
Multicenter Trial for Treatment of Acute Lymphoblastic Leukemia in Adults (05/93)Status: Completed, Estimated PCD: 1999-01-01
Clinical trial
A Multicentre, Randomised Phase II to Compare Epirubicin (E) & Cyclophosphamide (C) Treatment Plus Docetaxel (D) & Trastuzumab vs. E & C Treatment Plus D & Lapatinib in Women With Primary Resectable or Locally Advanced HER2+ Breast CancerStatus: Completed, Estimated PCD: 2011-12-01
Clinical trial
A Phase II Study of Doxil (Liposomal Doxorubicin), Cyclophosphamide, Vincristine and Prednisone for AIDS-Related Systemic LymphomaStatus: , Estimated PCD: 2003-04-01
Clinical trial
A Phase II Study of Dasatinib (Sprycel®) (NSC #732517) as Primary Therapy Followed by Transplantation for Adults >/= 18 Years With Newly Diagnosed Ph+ Acute Lymphoblastic Leukemia by CALGB, ECOG and SWOGStatus: Completed, Estimated PCD: 2017-11-14
Clinical trial
A Phase 1b Study to Evaluate HMBD-001 in Combination With Docetaxel With or Without Cetuximab in Participants With Advanced Squamous Non-small Cell Lung CancersStatus: Recruiting, Estimated PCD: 2026-04-01
Clinical trial
Adjuvant Dynamic Marker-Adjusted Personalized Therapy Trial Optimizing Risk Assessment and Therapy Response Prediction in Early Breast CancerStatus: Active (not recruiting), Estimated PCD: 2019-09-01
Clinical trial
Methotrexate and Prednisolone Study in Erythema Nodosum Leprosum (MaPS in ENLStatus: Recruiting, Estimated PCD: 2023-12-01
Clinical trial
A Study to Evaluate Serplulimab in Combination With Docetaxel +S-1 VS. Docetaxel +S-1 as Adjuvant Treatment Therapy in Stage IIIc Gastric Cancer(PD-L1 + / MSI-H / EBV +/dMMR)Status: Recruiting, Estimated PCD: 2025-03-31
Clinical trial
Phase 1/2 Study of Vincristine and Temozolomide in Combination With PEN-866 for Adolescents and Young Adults With Relapsed or Refractory Solid TumorsStatus: Not yet recruiting, Estimated PCD: 2026-02-28
Clinical trial
Multicenter Trial for Treatment of Acute Lymphocytic Leukemia in Adults (Pilot Study 06/99)Status: Completed, Estimated PCD: 2003-11-01
Clinical trial
A Randomized, Multi-Center, Phase III Trial of Calcineurin Inhibitor-Free Interventions for Prevention of Graft-versus-Host Disease (BMT CTN 1301; Progress II)Status: Completed, Estimated PCD: 2020-10-05
Clinical trial
Phase II Study of Timed Sequential Busulfan in Combination With Fludarabine in Allogeneic Stem Cell TransplantationStatus: Completed, Estimated PCD: 2022-08-11
Clinical trial
Multicenter Study To Optimize Treatment in Elderly Patients (> 55 Years, No Upper Age Limit) With Acute Lymphoblastic Leukemia (GMALL Elderly 1/2003)(Amend 2)Status: Completed, Estimated PCD: 2011-06-01
Clinical trial
Pediatric-inspired Regimen Combined With Venetoclax for Adolescent and Adult Patients With de Novo Philadelphia Chromosome-Negative Acute Lymphoblastic LeukemiaStatus: Recruiting, Estimated PCD: 2024-12-15
Clinical trial
A Single-Arm, Phase II Study of Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer: The SAPPHO Study:Status: Not yet recruiting, Estimated PCD: 2030-03-30
Clinical trial
A Phase II Study of Reduced Intensity Allogeneic Bone Marrow Transplant for the Treatment of Myelodysplastic SyndromesStatus: Completed, Estimated PCD: 2014-02-01
Clinical trial
Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors: Phase II Study of Chemotherapy, Photon and Heavy Ion Radiotherapy Integration for More Effective and Less Toxic Treatment in Inoperable PatientsStatus: , Estimated PCD: 2020-06-01
Clinical trial
Multidisciplinary Approach for Poor Prognosis Sinonasal Tumors: Phase II Study of Chemotherapy, Surgery, Photon and Heavy Ion Radiotherapy Integration for More Effective and Less Toxic Treatment in Operable PatientsStatus: , Estimated PCD: 2020-01-01
Clinical trial
A Multicenter Phase 1, Open-Label Trial of Loncastuximab Tesirine in Combination With DA-EPOCH-R in Patients With Previously Untreated Aggressive B-cell Lymphoid MalignanciesStatus: Recruiting, Estimated PCD: 2026-05-01
Clinical trial
The Registry to Observe Clinical Outcomes of Patients With High-risk Metastatic Hormone-naïve Prostate Cancer in JapanStatus: Active (not recruiting), Estimated PCD: 2024-08-31
Clinical trial
A Randomized Phase II Study Comparing Pembrolizumab With Methotrexate in Elderly, Frail or Cisplatin-ineligible Patients With Head and Neck CancersStatus: Terminated, Estimated PCD: 2021-11-24
Clinical trial
Assessing REsponse to Neoadjuvant Taxotere and Trastuzumab in Nigerian Women With HER2-positive Breast Cancer (ARETTA)Status: Recruiting, Estimated PCD: 2023-09-10
Clinical trial
Randomized Phase II Trial Contrasting Weekly Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell CarcinomaStatus: Active (not recruiting), Estimated PCD: 2025-12-31
Clinical trial
The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell Carcinoma: A Multi-center Randomized Controlled Prospective StudyStatus: Recruiting, Estimated PCD: 2025-11-01
Clinical trial
Phase III Study Comparing the Efficacy of Paclitaxel-bevacizumab With Docetaxel in 2nd or 3rd Line of Treatment of Non Squamous Non Small Cells Lung CancerStatus: Completed, Estimated PCD: 2015-12-01
Clinical trial
A Randomized Phase 2 Trial of Ascorbic Acid in Combination With Docetaxel in Men With Metastatic Prostate CancerStatus: Terminated, Estimated PCD: 2021-07-31
Clinical trial
Phase II Open-Label Trial of Tacrolimus/Methotrexate and Tocilizumab for the Prevention of Acute Graft-Versus-Host Disease After Allogeneic Hematopoietic Stem Cell TransplantationStatus: Completed, Estimated PCD: 2018-09-01
Clinical trial
Phase II Study of Dose Attenuated Chemotherapy in Patients With Lung Cancer and Age > 70 and/or ComorbiditiesStatus: Recruiting, Estimated PCD: 2028-08-01
Clinical trial
LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell HistiocytosisStatus: Recruiting, Estimated PCD: 2025-07-01
Clinical trial
A Study of Chemotherapy With WeiLeShu Versus Chemotherapy Alone in Patients With Metastatic Colorectal CancerStatus: Completed, Estimated PCD: 2021-10-30
Clinical trial
A Phase II Study of CHOEP Induction Followed by Gemcitabine/Busulfan/Melphalan Autologous Stem Cell Transplantation for Patients With Newly Diagnosed T-Cell LymphomaStatus: Terminated, Estimated PCD: 2014-10-01
Clinical trial
A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation With Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)Status: Recruiting, Estimated PCD: 2029-12-01
Clinical trial
A Phase I, Multicenter, Uncontrolled, Open Label Study Assessing the Efficacy and Safety of a Combination of Systemic and Intravitreal Injections of Methotrexate for the Prevention and Treatment of Proliferative Vitreoretinopathy in Pediatric Patients With RheGmatogenous Retinal DetacHmenT (the SIGHT Study)Status: Withdrawn, Estimated PCD: 2023-04-01
Clinical trial
A Phase Ib/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Initial Efficacy of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab and With Standard Chemotherapy in Patients With Advanced Lung CancerStatus: Recruiting, Estimated PCD: 2024-09-18
Clinical trial
A Phase 2 Study of Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary Central Nervous System LymphomaStatus: Recruiting, Estimated PCD: 2028-05-31
Clinical trial
A Phase II Single-arm Study of Tazemetostat With Docetaxel, Cisplatin, and 5-fluorouracil as Preoperative Treatment for Locally Advanced Potentially Resectable SMARCB1 (INI-1)- Deficient Sinonasal CarcinomaStatus: Not yet recruiting, Estimated PCD: 2026-08-31
Clinical trial
Efficacy and Safety of Rezvilutamide in Patients With Biochemical Recurrence After Radical Prostatectomy for Prostate Cancer: A Prospective, Multi-centre StudyStatus: Recruiting, Estimated PCD: 2027-03-01
Clinical trial
Phase II Study of Concurrent Cisplatin/Pemetrexed and RT Followed by Docetaxel in Stage III NSCLC (Non Small Cell Lung Cancer)Status: Completed, Estimated PCD: 2012-09-01
Clinical trial
Randomized Phase III Study Testing Nivolumab and Ipilimumab Versus a Carboplatin Based Doublet in First Line Treatment of PS 2 or Elderly (More Than 70 Years Old) Patients With Advanced Non-small Cell Lung CancerStatus: Completed, Estimated PCD: 2021-07-31
Clinical trial
Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2023-08-01
Clinical trial
Randomized Phase 2 Study Testing Two Conditioning Regimen With a Single Prophylaxis of Graft-versus-host Disease by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft TransplantationStatus: Not yet recruiting, Estimated PCD: 2027-09-15
Clinical trial
A Phase I Trial of Apalutamide Plus Abiraterone Acetate, Docetaxel, and Prednisone in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC)Status: Active (not recruiting), Estimated PCD: 2021-06-30
Clinical trial
International Phase 3 Trial in Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ALL) Testing Imatinib in Combination With Two Different Cytotoxic Chemotherapy BackbonesStatus: Recruiting, Estimated PCD: 2027-09-30
Clinical trial
A Multicenter, Prospective, Cohort Study on the Treatment of Metastatic Hormone-sensitive Prostate Cancer Patients Who Have Progressed After Pre-treatment With Rezvilutamide Combined With AbirateroneStatus: Not yet recruiting, Estimated PCD: 2025-04-30
Clinical trial
A Phase 1/2 Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid TumorsStatus: Recruiting, Estimated PCD: 2025-04-10
Clinical trial
A Multicenter Phase II Study of 18F-FDG PET/CT Guided Reduced-dose Radiotherapy for Nasopharyngeal CarcinomaStatus: Recruiting, Estimated PCD: 2024-06-30
Clinical trial
Phase II Trial of Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal CytologyStatus: Active (not recruiting), Estimated PCD: 2025-10-01
Clinical trial
Intensified Methotrexate, Nelarabine (Compound 506U78) and Augmented BFM Therapy for Children and Young Adults With Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (ALL) or T-cell Lymphoblastic LymphomaStatus: Active (not recruiting), Estimated PCD: 2017-09-30
Clinical trial
A Phase 2, Randomized, Open-label Three-arm Clinical Study to Evaluate the Safety and Efficacy of Lenvatinib (E7080/MK-7902) in Combination With Pembrolizumab (MK-3475) Versus Standard of Care Chemotherapy and Lenvatinib Monotherapy in Participants With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) That Have Progressed After Platinum Therapy and Immunotherapy (PD-1/PD-L1 Inhibitors) (LEAP-009)Status: Recruiting, Estimated PCD: 2025-07-18
Clinical trial
The PREDMETH Trial: Effectiveness of Methotrexate Versus Prednisolone as First-line Therapy for Pulmonary Sarcoidosis - A Randomized Controlled TrialStatus: Active (not recruiting), Estimated PCD: 2024-07-01
Clinical trial
ALinC 17: Protocol for Patients With Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia (ALL): A Phase III StudyStatus: Completed, Estimated PCD: 2005-07-01
Clinical trial
A Phase I Trial of Temsirolimus (CCI-779, Pfizer, Inc.) in Combination With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins LymphomaStatus: Completed, Estimated PCD: 2019-12-15
Clinical trial
Pharmacodynamic Biomarkers of Standard Anti-microtubule Drugs as Assessed by Early Tumor BiopsyStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
Open-label Phase I-II Clinical Trial to Evaluate Treatment With Myocet/Taxotere/Herceptin as Primary Chemotherapy Treatment for HER2neu Positive Breast Cancer PatientsStatus: Completed, Estimated PCD: 2008-12-01
Clinical trial
Study to Investigate Outcome of Individualized Treatment Based on Pharmacogenomic Profiling & Ex Vivo Drug Sensitivity Testing of Patient-derived Organoids in Patients With Metastatic Colorectal CancerStatus: Recruiting, Estimated PCD: 2038-12-31
Clinical trial
Randomized Phase II Trial of Stereotactic Body Radiation Therapy (SBRT) With Cetuximab +/- Docetaxel Followed by Adjuvant Cetuximab +/- Docetaxel in Recurrent, Previously-Irradiated Squamous Cell Carcinoma of the Head and Neck (SCCHN)Status: Completed, Estimated PCD: 2019-03-15
Clinical trial
A Phase III Trial to Evaluate the Efficacy of the Addition of Inotuzumab Ozogamicin (a Conjugated Anti-CD22 Monoclonal Antibody) to Frontline Therapy in Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALLStatus: , Estimated PCD: 2025-03-01
Clinical trial
STAMPEDE: Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy: A Multi-Stage Multi-Arm Randomised Controlled TrialStatus: Active (not recruiting), Estimated PCD: 2026-03-01
Clinical trial
Evaluation of Liver Function Test to Identify Hepatotoxcicity Among Acute Leukemia Patients Who Are Receiving Chemotherapy InductionStatus: Not yet recruiting, Estimated PCD: 2025-05-01
Clinical trial
A Phase II Trial of Trametinib With Docetaxel in Patients With KRAS Mutation Positive Non-Small Cell Lung Cancer (NSCLC) and Progressive Disease Following One or Two Prior Systemic TherapiesStatus: Active (not recruiting), Estimated PCD: 2019-05-15
Clinical trial
Efficacy and Safety of Perioperative Chemotherapy Combined With Tislelizumab and Trastuzumab in Patients With HER2-positive Resectable Gastric or Gastr-oesophageal Junction Carcinoma (GC/EGJ) -- a Prospective, Single-arm, Phase II StudyStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
(CompassHER2-pCR): Preoperative THP and Postoperative HP in Patients Who Achieve a Pathologic Complete ResponseStatus: Recruiting, Estimated PCD: 2026-10-31
Clinical trial
Concomitant Chemotherapy AND Bcl-xL Inhibitor (AT-101) For Bio-selection For Organ Preservation In Patients With Advanced Laryngeal CancerStatus: Completed, Estimated PCD: 2021-11-06
Clinical trial
A Multicenter, Open-Label Trial of Intravenous Golimumab, a Human Anti-TNFα Antibody, in Pediatric Subjects With Active Polyarticular Course Juvenile Idiopathic Arthritis Despite Methotrexate TherapyStatus: Active (not recruiting), Estimated PCD: 2018-07-09
Clinical trial
High-dose Chemotherapy for Poor-Prognosis Relapsed Germ-Cell TumorsStatus: Completed, Estimated PCD: 2024-01-11
Clinical trial
Phase II Study of Combination of Hyper-CVAD and Dasatinib in Patients With Philadelphia (Ph) Chromosome Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL)Status: Completed, Estimated PCD: 2024-02-02
Clinical trial
Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease With Laboratory and Clinical Correlates of Disease ActivityStatus: Active (not recruiting), Estimated PCD: 2025-10-01
Clinical trial
A Randomized Phase II Study Comparing Inotuzumab Plus Chemotherapy Versus Standard Chemotherapy in Older Adults With Philadelphia-Chromosome-Negative B-Cell Acute Lymphoblastic LeukemiaStatus: Recruiting, Estimated PCD: 2025-05-31
Clinical trial
Study of Regorafenib in Combination With Oral Methotrexate for KRAS Mutated Non-Small Cell Lung Cancer (NSCLC)Status: Completed, Estimated PCD: 2022-06-15
Clinical trial
A Phase 1 Study of NBTXR3 Activated by Radiotherapy With Concurrent Chemotherapy for Adenocarcinoma of the EsophagusStatus: Recruiting, Estimated PCD: 2025-10-31
Clinical trial
A Phase II Randomized Trial, Non Comparative, Evaluating Chemotherapy Associated Cisplatin, 5-fluorouracil and Docetaxel at Adapted Doses in Patients With Locally Advanced Squamous Cell CarcinomaStatus: Active (not recruiting), Estimated PCD: 2025-06-01
Clinical trial
Perioperative Immunotherapy vs. Chemo-immunotherapy Stratified by Early Response Evaluation in Patients With Advanced Gastric Cancer (GC) and Adenocarcinoma of the Esophago-gastric Junction (AEG)Status: Active (not recruiting), Estimated PCD: 2024-03-01
Clinical trial
UpFrontPSMA : A Randomised Phase 2 Study of Sequential 177Lu-PSMA617 and Docetaxel Versus Docetaxel in Metastatic Hormone-Naive Prostate CancerStatus: Active (not recruiting), Estimated PCD: 2024-04-01
Clinical trial
A Randomized Trial for Adults With Newly Diagnosed Acute Lymphoblastic LeukemiaStatus: Active (not recruiting), Estimated PCD: 2024-12-01
Clinical trial
A Phase 1 First-in-Human Study With ABBV-155 Alone and in Combination With Taxane Therapy in Adults With Relapsed and/or Refractory Solid TumorsStatus: Active (not recruiting), Estimated PCD: 2024-12-31
Clinical trial
A Prospective Pilot Study to Evaluate the Feasibility of Intensity Modulated Proton Therapy in Reducing Toxicity in Anal CancerStatus: Active (not recruiting), Estimated PCD: 2022-04-07
Clinical trial
A Controlled, Randomized Phase II Trial of Docetaxel Plus Trastuzumab Versus Ado-Trastuzumab Emtansine for Recurrent, Metastatic, or Treatment-Naive, Unresectable HER2-Positive Salivary Gland CancerStatus: Recruiting, Estimated PCD: 2028-07-31
Clinical trial
Phase I-II Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone SarcomasStatus: Recruiting, Estimated PCD: 2025-06-30
Clinical trial
Phase I Study of Afatinib With Postoperative Radiation Therapy for Intermediate and High Risk Squamous Cancer of the Head and Neck (SCCHN)Status: Completed, Estimated PCD: 2017-11-20
Clinical trial
The Efficacy and Safety of Pyrotinib, Trastuzumab Combined With Taxanes in the Treatment of Early Trastuzumab-treated HER2+ Advanced Breast Cancer (ABC).Status: Recruiting, Estimated PCD: 2025-12-11
Clinical trial
A Phase II Randomized Controlled Trial Comparing GVHD-Reduction Strategies for Allogeneic Peripheral Blood Transplantation (PBSCT) for Patients With Acute Leukemia or Myelodysplastic Syndrome: Selective Depletion of CD45RA+ Naïve T Cells (TND) vs. Post-Transplantation Cyclophosphamide (PTCy)Status: Recruiting, Estimated PCD: 2026-12-31
Clinical trial
A Phase Ib/II Trial of Cadonilimab (PD-1/CTLA-4 Bispecific Antibody) in Combination With Anlotinib and Docetaxel in Patients (Pts) With Checkpoint Inhibitor (CPI)-Experienced Advanced Non-small Cell Lung Cancer (NSCLC)Status: Recruiting, Estimated PCD: 2024-12-30
Clinical trial
Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With GlioblastomaStatus: Recruiting, Estimated PCD: 2026-11-21
Clinical trial
A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women With Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast CancerStatus: Active (not recruiting), Estimated PCD: 2017-07-31
Clinical trial
Risk-Adapted Therapy for HIV-Associated Anal CancerStatus: Recruiting, Estimated PCD: 2029-09-15
Clinical trial
A Randomized Phase III Study Comparing Cyclophosphamide + Methotrexate + Fluorouracil vs. Goserelin + Tamoxifen in Premenopausal, Hormone Receptor-positive, Lymph Node-positive or -Negative PatientsStatus: Completed, Estimated PCD: 2004-06-01
Clinical trial
Clinical Study of Curcumin in Preventing Postoperative Adhesion of Bilateral Vocal CordsStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
CHemotherapy Plus Enzalutamide In First Line Therapy for Castration Resistant prOstate caNcerStatus: Completed, Estimated PCD: 2018-04-01
Clinical trial
Randomized Phase 3 Trial Evaluating the Addition of the IGF-1R Monoclonal Antibody Ganitumab (AMG 479, NSC# 750008) to Multiagent Chemotherapy for Patients With Newly Diagnosed Metastatic Ewing SarcomaStatus: Active (not recruiting), Estimated PCD: 2021-03-31
Clinical trial
CHildren Treated With Vincristine: A Trial Regarding Pharmacokinetics, DNA And Toxicity of Targeted Therapy In Pediatric Oncology Patients.Status: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
A Randomized Phase II Study of 177 LuPSMA-617 vs Docetaxel in Patients With Metastatic Castration-Resistant Prostate Cancer and PSMA-Positive DiseaseStatus: Active (not recruiting), Estimated PCD: 2024-07-31
Clinical trial
Immunotherapy With Chemotherapy and Chemoradiation for Advanced Squamous Cancer of Nasal Cavity / Paranasal Sinuses (I-NAPA)Status: Recruiting, Estimated PCD: 2026-03-30
Clinical trial
A Phase 3 Study of Erdafitinib Compared With Vinflunine or Docetaxel or Pembrolizumab in Subjects With Advanced Urothelial Cancer and Selected FGFR Gene AberrationsStatus: Active (not recruiting), Estimated PCD: 2024-09-11
Clinical trial
Subcutaneous Methotrexate, Oral Dexamethasone or Oral Montelukast for the Prevention of Infusion Related Reaction Associated With Amivantamab, an EGFR-MET Bispecific Antibody, Among Post-osimertinib Treated EGFRm NSCLC; SKIPPirr, a Phase 2 StudyStatus: Active (not recruiting), Estimated PCD: 2024-12-15
Clinical trial
A Randomized International Phase 3 Trial of Imatinib and Chemotherapy With or Without Blinatumomab in Patients With Newly-Diagnosed Philadelphia Chromosome-Positive or Philadelphia Chromosome-Like ABL-Class B-Cell Acute Lymphoblastic LeukemiaStatus: Not yet recruiting, Estimated PCD: 2030-12-01
Abstract
Prostate irradiation in men with de novo, low-volume, metastatic, castration-sensitive prostate cancer (mCSPC): Results of PEACE-1, a phase 3 randomized trial with a 2x2 design.Org: Gustave Roussy Institute, Bergonié Institute, Léon Bérard Cancer Center, Institut de Cancérologie de l'Ouest, Azuréen Center of Oncology,
Abstract
Longitudinal MRI-based radiomic model to complement sentinel lymph node biopsy assessment after neoadjuvant chemotherapy in initially clinically node-positive breast cancer: A multicentre, diagnostic study.Org: Department of Breast Cancer, Hubei Cancer Hospital, Wuhan, China, Cancer Center, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China, Southern Medical University, The First People’s Hospital of Foshan,
Abstract
Safety, tolerability, and quality of life (QoL) of single-agent plinabulin (Plin) for the prevention of docetaxel (Doc) chemotherapy (chemo)-induced neutropenia (CIN) in non-small cell lung cancer (NSCLC) patients (pts) from two randomized trials.Org: Stanford Cancer Institute, BeyondSpring Pharmaceuticals, Inc.,
Abstract
Prognostic value of baseline immune suppressive biomarkers to select non-small cell lung cancer (NSCLC) patients (pts) likely to benefit from the plinabulin/docetaxel (Plin/Doc) combination.Org: Piedmont Cancer Institue, BeyondSpring Pharmaceuticals, Inc.,
Abstract
Outcomes of myeloid malignancies in patients previously treated with PARP inhibitors for solid malignancies: A single institution experience.Org: University of Texas MD Anderson Cancer Center, The University of Texas at MD Anderson Cancer Center, MD Anderson Cancer Center, Department of Leukemia,
Abstract
Characterization of drug and non-drug interactions in patients treated in medical oncology.Org: Faculty of Medicine, University of Tlemcen, Department of Medicine, Laboratoire Toxicomed, University of Tlemcen, Department of Medical Oncology, CHU Tlemcen,
Abstract
Impact of PD-L1 and KRAS status on the efficacy of nintedanib (NIN) + docetaxel (DOC) following treatment with first-line immune checkpoint inhibitor (ICI) + chemotherapy in patients with adenocarcinoma NSCLC: Analysis of cohort C of the non-interventional VARGADO trial.Org: Department of Respiratory Diseases, ELK Berlin, Universitätsklinikum Gießen und Marburg, Medizinische Klinik IV, Organonkologie, Innere Medizin V, Medizinische Klinik, Universitätskliniken des Saarlandes, Department of Internal Medicine, Klinikum Chemnitz GmbH,
Abstract
Prevention of chemotherapy-induced neutropenia (CIN) with plinabulin (Plin) vs placebo (Plac) in patients (pts) with non-small cell lung cancer (NSCLC) treated with docetaxel (Doc): A pooled analysis from 3 randomized trials.Org: Stanford Cancer Institute, Stanford, CA, BeyondSpring Pharmaceuticals, Inc., New York, NY, Newyork, NY,
Abstract
Real-world efficacy of chemotherapy in patients with advanced extramammary Paget's disease: A retrospective, multicenter study of 204 Japanese patients.Org: Kumamoto University Hospital, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan, Nagoya City University Graduate School of Medical Sciences, National Cancer Center Hospital East, Kashiwa, Japan, Graduate School of Medicine, Chiba University,
Product
Docetaxel + Cisplatin HIPECProduct
MethotrexateProduct
ADT with or without docetaxel plus abiraterone acetate, prednisone, and prostate radiotherapyProduct
IMM2520Product
ADT + Docetaxel + NivolumabProduct
TaxanesProduct
Placebo + MethotrexateProduct
darolutamide + docetaxelProduct
Docetaxel + PlaceboProduct
Tislelizumab + TPF + CCRTProduct
DKN-01 + docetaxelProduct
sintilimab plus docetaxelProduct
SIMPONI + MTXProduct
placebo + ADT + docetaxelProduct
Docetaxel + Prostvac + ADTProduct
conventional chemotherapyProduct
docetaxel + ramucirumabProduct
Plinabulin + DocetaxelProduct
Docetaxel + PevonedistatProduct
Induction chemo-immunotherapy followed by chemoradiation with or without maintenance immunotherapyProduct
M9241 + Docetaxel + ADTProduct
Docetaxel + PlinabulinProduct
ADT + ApalutamideProduct
Adalimumab + MethotrexateProduct
Docetaxel, CisplatinProduct
docetaxel and prednisoneProduct
anlotinib + docetaxelProduct
Docetaxel plus TrametinibProduct
Docetaxel, S1Product
Surufatinib + DocetaxelProduct
Rezvilutamide + DocetaxelProduct
TCHPProduct
Docetaxel + IV Vitamin CProduct
Anlotinib plus DocetaxelProduct
Other maintenance therapyProduct
placebo + MTXProduct
ramucirumab + docetaxelProduct
ADT+ARPIProduct
ADT + cemiplimab + docetaxelProduct
NAP + DocetaxelProduct
TaxaneProduct
darolutamide, docetaxel, ADTProduct
Docetaxel + Radium-223Product
selinexor + docetaxelClinical trial
Abatacept for Graft Versus Host Disease Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease: a Sickle Transplant Alliance for Research TrialStatus: Completed, Estimated PCD: 2021-12-30
Clinical trial
BCG + MMC: Adding Mitomycin C to BCG as Adjuvant Intravesical Therapy for High-risk, Non-muscle-invasive Bladder Cancer: a Randomised Phase 3 TrialStatus: Active (not recruiting), Estimated PCD: 2026-12-01
Clinical trial
Development and Validation of the ChemoResist Signature Precisely Predictive of Chemotherapy Sensitivity in Resected Pancreatic Ductal AdenocarcinomaStatus: Completed, Estimated PCD: 2020-03-16
Clinical trial
Fourth Ventricular Administration of Immune Checkpoint Inhibitor (Nivolumab) and Methotrexate or 5-Azacytidine for Recurrent Medulloblastoma, Ependymoma, and Other CNS MalignanciesStatus: Not yet recruiting, Estimated PCD: 2027-07-01
Clinical trial
To Evaluate the Efficacy and Safety of Adebrelimab Combined With Chemotherapy Neoadjuvant Therapy in Early or Local Advanced Breast Cancer After Induction Treatment of High-intensity Focused Ultrasound and AdebrelimabStatus: Not yet recruiting, Estimated PCD: 2026-06-01
Clinical trial
Evaluation of Clinical Outcomes of Chemotherapy or Androgen-receptor Targeting Therapy (Alone or in Combination) or Radiotherapy on the Primary Tumor in Combination With Androgen Deprivation Therapy in Metastatic Hormone-sensitive Prostate Cancer: Multicenter Observational Study of Patients Undergoing Treatment in Clinical Practice in Italian HospitalsStatus: Recruiting, Estimated PCD: 2026-12-01
Clinical trial
A Randomised, Open-label, Phase 3 Trial Comparing the Efficacy and Safety of OSE2101 Versus Docetaxel in HLA-A2 Positive Patients With Metastatic Non-Small Cell Lung Cancer (NSCLC) With Secondary Resistance to Immune Checkpoint InhibitorStatus: Not yet recruiting, Estimated PCD: 2027-12-15
Clinical trial
Comparison of Efficacy of Methotrexate and Azathioprine in Patients With Chronic Actinic DermatitisStatus: Not yet recruiting, Estimated PCD: 2025-07-13
Clinical trial
A Pilot Study of Pembrolizumab in Combination With Chemotherapy in Newly Diagnosed Primary Central Nervous System LymphomaStatus: Not yet recruiting, Estimated PCD: 2025-06-30
Clinical trial
Ebastine in Combination With Docetaxel as a Treatment for Castration-resistant Metastatic Prostate CancerStatus: Recruiting, Estimated PCD: 2026-12-01
Clinical trial
Dendritic Cell Vaccination in Combination With Docetaxel for Patients With Cancer Prostate - a Randomized Phase II StudyStatus: Completed, Estimated PCD: 2015-08-01
Clinical trial
Intravesical Gemcitabine and Docetaxel for Low Grade Intermediate Risk Bladder CancerStatus: Not yet recruiting, Estimated PCD: 2027-08-01