Organization
Erasmus Medical Center
44 clinical trials
9 abstracts
5 posters
Abstract
Primary outcome analysis of the ORCHESTRA trial: A randomized phase III trial of additional tumor debulking to first-line palliative systemic therapy for patients with multiorgan metastatic colorectal cancer.Org: Radboud UMC, Erasmus Medical Center, Radboud University Medical Center and Radboud Institute for Molecular Life Sciences, Amsterdam UMC location VUMC, Erasmus MC Cancer Institute,
Abstract
Zotiraciclib for newly diagnosed or recurrent glioblastoma: Updated outcome and biomarker analysis.Org: University Hospital Zurich, Brain Tumor Centre, University of Zurich, EORTC Headquarters, Institute of Neuropathology,
Clinical trial
Total Neoadjuvant Therapy for Adenocarcinoma of the OESophagus and Oesophagogastric Junction: TNT-OES-2 TrialStatus: Not yet recruiting, Estimated PCD: 2029-09-01
Clinical trial
Top-down Infliximab Study in Kids With Crohn's DiseaseStatus: Completed, Estimated PCD: 2019-12-01
Clinical trial
Evaluation of the Omission of Dexamethasone in Premedication Regimens During Paclitaxel TreatmentStatus: Not yet recruiting, Estimated PCD: 2027-01-01
Clinical trial
Azole-echinocandin Combination Therapy for Invasive Aspergillosis A Randomized Pragmatic Superiority TrialStatus: Terminated, Estimated PCD: 2024-05-01
Clinical trial
Phase I/II Study to Determine the Safety, Immunogenicity and Efficacy of the Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination ISA104Status: Recruiting, Estimated PCD: 2024-09-01
Clinical trial
Nivolumab Dose Optimization in Patients With a Complete, Partial or Stable ResponseStatus: Recruiting, Estimated PCD: 2024-10-01
Clinical trial
Chemotherapy and Sequential Immunotherapy for Locally Advanced Urothelial Cancer: the CHASIT StudyStatus: Recruiting, Estimated PCD: 2025-04-01
Clinical trial
Dual Thrombolytic Therapy With Mutant Pro-urokinase (M-pro-urokinase, HisproUK) and Low Dose Alteplase for Ischemic StrokeStatus: Completed, Estimated PCD: 2022-03-26
Clinical trial
Predicting an Accurate Tamoxifen Dose: a Feasibility Study in Patients With Hormone Sensitive Breast CancerStatus: Recruiting, Estimated PCD: 2023-12-31
Clinical trial
FUnctional Selection of Advanced Breast Cancer Patients for Talazoparib Treatment Using the REpair Capacity (RECAP) Test: The FUTURE TrialStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
Optimizing Reversal of HIV Latency With Combination Therapy (Pyrimethamine, Lenalidomide, Panobinostat)Status: Not yet recruiting, Estimated PCD: 2025-05-01
Clinical trial
Adoptive Therapy With TCR Gene-engineered T Cells to Treat Patients With MAGE-C2-positive Melanoma and Head and Neck CancerStatus: Recruiting, Estimated PCD: 2024-12-20
Clinical trial
Doxapram Versus Placebo in Preterm Newborns: An International Double Blinded Multicenter Randomized Controlled TrialStatus: Recruiting, Estimated PCD: 2026-05-01
Clinical trial
INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701Status: Withdrawn, Estimated PCD: 2024-02-16
Clinical trial
Prospective Analysis of Pharmacokinetic Infliximab Data in Pediatric CD Patients (ProRAPID)Status: Recruiting, Estimated PCD: 2025-01-01
Clinical trial
Concomitant Intraperitoneal and Systemic Chemotherapy in Patients With Extensive Peritoneal Carcinomatosis of Gastric OriginStatus: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
Guided by Light: Optimizing Surgical Excision of Oral Cancer Using Real-time Fluorescence ImagingStatus: Recruiting, Estimated PCD: 2024-09-01
Clinical trial
Resistance Under the Microscope; a Randomized Placebo Controlled Parallel Group DesignStatus: Completed, Estimated PCD: 2011-09-01
Clinical trial
A Randomized Phase II Trial of Docetaxel or Cabazitaxel With or Without Darolutamide in Men With Metastatic Castration-resistant Prostate CancerStatus: Recruiting, Estimated PCD: 2027-05-01
Clinical trial
Safe Stop IPI-NIVO Trial: Early Discontinuation of Nivolumab Upon Achieving a (Confirmed) Complete or Partial Response in Patients With Irresectable Stage III or Metastatic Melanoma Treated With First-line Ipilimumab-nivolumabStatus: Recruiting, Estimated PCD: 2025-12-01
Clinical trial
Heavy Isotope-labeled-butyrate and Glucose in Breath Testing to Detect Mesenteric Ischemia, a Proof-of-concept Study in Healthy Volunteers.Status: Completed, Estimated PCD: 2021-04-01
Clinical trial
Intraperitoneal Paclitaxel for Patients With Primary Malignant Peritoneal Mesothelioma - a Phase I/II Dose Escalation and Safety StudyStatus: Recruiting, Estimated PCD: 2026-02-01
Clinical trial
Treatment of Vascular Stiffness in Patients With Autosomal Dominant Polycystic Kidney DiseaseStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
Adjuvant Nonavalent HPV Vaccination in Women Treated for Vulvar HSIL, a Randomised Placebo Controlled TrialStatus: Not yet recruiting, Estimated PCD: 2028-12-01
Clinical trial
Perioperative Versus Adjuvant FOLFIRINOX for Resectable Pancreatic Cancer: the PREOPANC-3 StudyStatus: Recruiting, Estimated PCD: 2026-02-01
Clinical trial
Long-term Pain Modulation by Intravenous Esketamine in Complex Regional Pain Syndrome: a Non-inferiority StudyStatus: , Estimated PCD: 2026-10-01
Clinical trial
Adherence to Lifestyle Changes for Age-related Macular DegenerationStatus: Active (not recruiting), Estimated PCD: 2025-08-01
Clinical trial
Prospective Individualization of the First Vancomycin Dose Using Population Pharmacokinetic Models.Status: Not yet recruiting, Estimated PCD: 2025-10-01
Clinical trial
Phase I, Open-Label Study With Dendritic Cell Therapy (MesoPher) In Combination With Ex-tended-Pleurectomy/Decortication After Chemotherapy in Subjects With Resectable MesotheliomaStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
Personalized Targeted Immunomodulation in Patients With ARDS Related to COVID19 and Future Pandemic PathogensStatus: Completed, Estimated PCD: 2022-02-01
Clinical trial
The STELLAR Trial: Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility TrialStatus: Not yet recruiting, Estimated PCD: 2025-05-01
Clinical trial
Ex Vivo Tumor Visualization and Resection Margin Assessment Using Topically Applied Fluorescent Imaging AgentsStatus: Not yet recruiting, Estimated PCD: 2027-12-01
Clinical trial
T-cell Epitopes Associated With Impaired Peptide Processing (TEIPP)- Targeting Immunotherapy in Patients With Relapsed Advanced Non Small Cell Lung Cancer (NSCLC)Status: Recruiting, Estimated PCD: 2024-07-01
Clinical trial
Improving Peptide Receptor Radionuclide Therapy With PARP InhibitorsStatus: Recruiting, Estimated PCD: 2025-01-01
Clinical trial
The Effect of Switching the H1-antagonist Clemastine to Cetirizine in Premedication Regimens During Paclitaxel Treatment: 'The H1-SWITCH Study'Status: Completed, Estimated PCD: 2023-04-27
Clinical trial
Pediatric Analgesia After Cardiac Surgery; Morphine IV Versus Paracetamol IV After Cardiac Surgery in Neonates and Infants.Status: Completed, Estimated PCD: 2020-07-11
Clinical trial
Biomarker Identification of Radionuclide Therapy-induced Radiation ResponsesStatus: Recruiting, Estimated PCD: 2024-10-01
Clinical trial
Investigator Led, Double-masked, Multicenter, Randomized Clinical Trial for the Comparison of Atropine 0.5% Versus Atropine 0.05% Eye Drops for the Prevention of Myopia Progression in Dutch ChildrenStatus: Recruiting, Estimated PCD: 2028-12-01
Clinical trial
The Efficacy of Laser Hair Removal Therapy in Patients With Mild to Moderate HS, a Randomized Controlled Trial.Status: Not yet recruiting, Estimated PCD: 2024-12-01
Clinical trial
SWITCH ON: Analysing the Immunogenicity of Additional Booster Vaccinations in Healthcare Workers. A Multicenter, Randomised, Controlled TrialStatus: Active (not recruiting), Estimated PCD: 2022-09-15
Clinical trial
Nivolumab During Active Surveillance After Neoadjuvant Chemoradiation for Esophageal Cancer: SANO-3 StudyStatus: Recruiting, Estimated PCD: 2025-04-01
Clinical trial
Formoterol-beclomethasone in Patients With Bronchiectasis: a Randomized Controlled TrialStatus: Terminated, Estimated PCD: 2022-07-05
Clinical trial
The PREDMETH Trial: Effectiveness of Methotrexate Versus Prednisolone as First-line Therapy for Pulmonary Sarcoidosis - A Randomized Controlled TrialStatus: Active (not recruiting), Estimated PCD: 2024-07-01
Clinical trial
A Phase I/II Clinical Trial Investigating the Effect of Topiramate on the Reactivation of the HIV-1 Reservoir in People Living With HIV on Antiretroviral TherapyStatus: Not yet recruiting, Estimated PCD: 2025-04-01
Abstract
Genome-wide aneuploidy detected in circulating cell-free DNA of patients with metastatic urothelial cancer as a predictive biomarker of response to pembrolizumab.Org: Erasmus MC Cancer Institute, University Medical Center, Department of Hematology, Rotterdam, Netherlands, Erasmus University Rotterdam, Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy, Italy, Amphia Hospital, Cancer Center Amsterdam,
Abstract
The relationship between a priori defined prognostic risk groups and and overall survival (OS) in men with metastatic hormone sensitive prostate cancer (mHSPC).Org: Duke University Medical Center, Duke University School of Medicine, Department of Head and Neck Surgery & Communication Sciences, Durham, NC, MRC Clinical Trials Unit at UCL, Northwestern University, Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center, SWOG Statistical Center,
Abstract
Upfront palliative resection of primary tumor versus no resection in patients with synchronous metastatic colorectal cancer: The randomized phase 3 CAIRO4 study of the Dutch Colorectal Cancer Group (DCCG).Org: University Medical Center Utrecht, Utrecht University, Netherlands Comprehensive Cancer Organisation (IKNL), Erasmus Medical Center, Amsterdam University Medical Centers,
Abstract
Assessing PSA levels as prognostic of overall survival (OS) in men with metastatic hormone-sensitive prostate cancer (mHSPC).Org: Duke University Medical Center, Duke University School of Medicine, Department of Head and Neck Surgery & Communication Sciences, Durham, NC, MRC Clinical Trials Unit at UCL, Northwestern University, Feinberg School of Medicine, Robert H. Lurie Comprehensive Cancer Center, SWOG Statistical Center,
Abstract
Analysis of significant weight gain in patients using alectinib for ALK-positive lung cancer.Org: Erasmus MC Cancer Institute, University Medical Center, Department of Hematology, Rotterdam, Netherlands, Erasmus MC University Medical Center, Erasmus Medical Center, Erasmus MC Kankerinstituut, Department of Pulmonary Medicine,
Abstract
ANTI-TNF-ALPHA INHIBITS THE ANTIBODY RESPONSE TO INFLUENZA VACCINATIONOrg: Rheumatology, Society of Patients with Rheumatism, Cracow, Poland, Infectious Diseases Physicians, gastro-enterology, Leiden University Medical Center, Leiden University,
Abstract
ANTIBODIES SPECIFIC FOR THE CITRULLINE-RESIDUE OF CITRULLINE-CONTAINING PROTEINS IN A MOUSE MODEL OF RHEUMATOID ARTHRITISOrg: Rheumatology, Society of Patients with Rheumatism, Cracow, Poland, Immunology, UKM, Muenster, Germany, Erasmus Medical Center, Human Genetics, The Genome Institute of Singapore, Singapore, Singapore, Leiden University Medical Center,