Organization
NCIC Clinical Trials Group
59 clinical trials
2 abstracts
Abstract
A biomarker-directed, multi-center phase II/III study of ctDNA molecular response adaptive immuno-chemotherapy in patients with non-small cell lung cancer.Org: NCIC Clinical Trials Group,
Clinical trial
A Randomized Phase III Study Of Thalidomide And Prednisone As Maintenance Therapy Following Autologous Stem Cell Transplant in Patients With Multiple MyelomaStatus: Completed, Estimated PCD: 2011-10-19
Clinical trial
A Phase II Study of PF-03446962 in Patients With Advanced Malignant Pleural MesotheliomaStatus: Completed, Estimated PCD: 2014-04-27
Clinical trial
A Feasibility Study of Pre-Operative Sunitinib (SU11248) With Multiple Pharmacodynamic Endpoints in Patients With T1c-T3 Operable Carcinoma of the BreastStatus: Completed, Estimated PCD: 2010-03-15
Clinical trial
A Phase II Study of SB939 in Patients With Translocation-Associated Recurrent/Metastatic SarcomasStatus: Completed, Estimated PCD: 2013-01-21
Clinical trial
A Double Blind Randomized Trial of Cediranib Versus Placebo in Patients Receiving Paclitaxel/Carboplatin Chemotherapy for the Treatment of Advanced or Metastatic Non-Small Cell Lung CancerStatus: Completed, Estimated PCD: 2012-01-09
Clinical trial
A Phase III Randomized Study of Exemestane Versus Placebo in Postmenopausal Women at Increased Risk of Developing Breast CancerStatus: Completed, Estimated PCD: 2011-03-25
Clinical trial
A Phase I/II Study Of Increasing Doses Of Epirubicin And Docetaxel Plus Pegfilgrastim For Locally Advanced Or Inflammatory Breast CancerStatus: Completed, Estimated PCD: 2010-01-06
Clinical trial
A Randomized Phase III Double-Blind Study of Dexamethasone Versus Placebo in the Prophylaxis of Radiation-Induced Pain Flare Following Palliative Radiotherapy for Bone MetastasesStatus: Completed, Estimated PCD: 2015-05-25
Clinical trial
A Phase I Study to Determine the Dose of Methadone as a First Line Agent in the Treatment of Chronic Neuropathic Cancer PainStatus: Terminated, Estimated PCD: 2012-01-06
Clinical trial
A Phase III Randomized Study of BBI608 and Best Supportive Care Versus Placebo and Best Supportive Care in Patients With Pretreated Advanced Colorectal CarcinomaStatus: Completed, Estimated PCD: 2016-05-07
Clinical trial
A Phase I/II Study of Foretinib in Combination With Lapatinib in Patients With Human Epidermal Growth Factor Receptor 2(HER2)Over-Expressing Metastatic Breast CancerStatus: Completed, Estimated PCD: 2014-05-14
Clinical trial
A Phase II Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or ProgressionStatus: Completed, Estimated PCD: 2014-10-29
Clinical trial
A Phase II Study of AT7519M, a CDK Inhibitor, in Patients With Relapsed Mantle Cell LymphomaStatus: Completed, Estimated PCD: 2014-12-02
Clinical trial
A Phase II Study of AT9283 in Patients With Relapsed or Refractory Multiple MyelomaStatus: Completed, Estimated PCD: 2014-10-29
Clinical trial
A Phase II Study Of SB-715992 (NSC 727990) In Patients With Locally Advanced, Recurrent Or Metastatic Hepatocellular CarcinomaStatus: Completed, Estimated PCD: 2006-09-26
Clinical trial
A Randomized Phase III Trial Of Exemestane Versus Anastrozole In Postmenopausal Women With Receptor Positive Primary Breast CancerStatus: Completed, Estimated PCD: 2010-11-07
Clinical trial
A Phase II Study of Cisplatin and Gemcitabine in Patients With Locally Advanced/Recurrent or Metastatic Malignant Salivary Gland TumorsStatus: Completed, Estimated PCD: 2008-09-29
Clinical trial
A Phase III Study of IRESSA in Combination With Intravesical BCG Versus Intravesical BCG Alone in High Risk Superficial Transitional Cell Carcinoma of the BladderStatus: Terminated, Estimated PCD: 2012-01-06
Clinical trial
A Phase II Study of SB939 in Patients With Recurrent or Metastatic Castration Resistant Prostate CancerStatus: Completed, Estimated PCD: 2015-01-05
Clinical trial
A Phase I, Open-Label, Dose-Seeking Study of AZD2171 Given Daily Orally in Combination With Standard Chemotherapy Regimens (CT) in Patients With Advanced Incurable Non-Small Cell Lung Cancer (NSCLC) or Colorectal Cancer or Other Tumor Types Suitable for Treatment With CapecitabineStatus: Completed, Estimated PCD: 2009-10-23
Clinical trial
A Phase II Study of Foretinib in Patients With Estrogen Receptor (ER), Progesterone Receptor (PR), and Human Epidermal Growth Factor Receptor 2 (HER2) Negative, Recurrent/Metastatic Breast CancerStatus: Completed, Estimated PCD: 2014-12-14
Clinical trial
A Randomized Phase II Dose Finding Study of Revlimid™ and Melphalan in Patients With Previously Untreated Multiple MyelomaStatus: Completed, Estimated PCD: 2008-06-30
Clinical trial
A Phase II Study Of Perifosine (D-21266) In Previously Untreated Patients With Metastatic Or Recurrent Malignant MelanomaStatus: Completed, Estimated PCD: 2004-09-14
Clinical trial
A Phase I, Open-Label, Dose-Seeking Study of AZD2171 Given Daily Orally in Combination With Selected Standard Chemotherapy Regimens (CT) in Patients With Advanced Incurable Non-Small Cell Lung Cancer (NSCLC) or Colorectal CancerStatus: Completed, Estimated PCD: 2007-09-18
Clinical trial
A Phase I/II Study of AZD0530 in Combination With Gemcitabine in Patients With Advanced Pancreatic CancerStatus: Completed, Estimated PCD: 2009-01-08
Clinical trial
A Phase I Study of AT9283 Given As a 24 Hour Infusion on Days 1 and 8 Every Three Weeks in Patients With Advanced Incurable MalignancyStatus: Completed, Estimated PCD: 2010-04-09
Clinical trial
A Phase II Study of Triapine (NSC 663249) in Previously Untreated Patients With Recurrent Renal Cell CarcinomaStatus: Completed, Estimated PCD: 2005-10-04
Clinical trial
A Phase I Study of SB939 in Pediatric Patients With Refractory Solid Tumours and LeukemiaStatus: Completed, Estimated PCD: 2012-04-12
Clinical trial
A Phase III Randomized Study of Cetuximab (Erbitux™, C225) and Best Supportive Care Versus Best Supportive Care in Patients With Pretreated Metastatic Epidermal Growth Factor Receptor (EGFR)-Positive Colorectal CarcinomaStatus: Completed, Estimated PCD: 2006-11-03
Clinical trial
A Phase II Study Of BAY 43-9006 (NSC 724772; CTEP IND# 69,896) In Patients With Hormone Refractory Prostate CancerStatus: Completed, Estimated PCD: 2006-09-28
Clinical trial
A Phase II Study Of Perifosine (D-21266) In Patients With Previously Untreated Metastatic Or Locally Advanced Soft Tissue SarcomaStatus: Completed, Estimated PCD: 2004-09-18
Clinical trial
A Phase I/II Study of Foretinib in Patients With Previously Treated Non-Small Cell Lung Cancer Receiving Standard Erlotinib TherapyStatus: Completed, Estimated PCD: 2014-03-21
Clinical trial
A Phase I Study of AEG35156 Given as a 2 Hour Intravenous Infusion in Combination With Docetaxel in Patients With Solid TumoursStatus: Completed, Estimated PCD: 2009-03-24
Clinical trial
A Phase III Study of Standard Fractionation Radiotherapy With Concurrent High-Dose Cisplatin Versus Accelerated Fractionation Radiotherapy With Panitumumab in Patients With Locally Advanced Stage III and IV Squamous Cell Carcinoma of the Head and NeckStatus: Completed, Estimated PCD: 2015-05-16
Clinical trial
A Phase I Study of AT7519M Given Twice Weekly in Patients With Advanced Incurable MalignancyStatus: Completed, Estimated PCD: 2012-03-13
Clinical trial
A Phase I Clinical and Pharmacokinetic Study of SB939 in Patients With Advanced CancerStatus: Completed, Estimated PCD: 2010-04-22
Clinical trial
A Phase II Study of Interleukin-21 (IL-21) in Patients With Metastatic or Recurrent Malignant MelanomaStatus: Completed, Estimated PCD: 2010-09-02
Clinical trial
A Phase II/III Double Blind Randomized Trial of AZD2171 Versus Placebo in Patients Receiving Paclitaxel/Carboplatin Chemotherapy for the Treatment of Advanced or Metastatic Non-Small Cell Lung CancerStatus: Completed, Estimated PCD: 2008-07-04
Clinical trial
A Phase I Study of Adjuvant OSI-774 (Tarceva®) in Patients Following Combined Chemo-Radiotherapy for Locally Advanced Squamous Cell Carcinoma of the Head and NeckStatus: Completed, Estimated PCD: 2008-12-09
Clinical trial
A Phase II Study of AT7519M, a CDK Inhibitor, in Patients With Relapsed and/or Refractory Chronic Lymphocytic LeukemiaStatus: Completed, Estimated PCD: 2014-03-21
Clinical trial
A Double Blind Placebo Controlled Randomized Trial of PF-804 in Patients With Incurable Stage IIIB/IV Non-Small Cell Lung Cancer After Failure of Standard Therapy for Advanced or Metastatic DiseaseStatus: Completed, Estimated PCD: 2014-01-15
Clinical trial
A Phase II Study of Ridaforolimus in Patients With Metastatic And/Or Locally Advanced Recurrent Endometrial CancerStatus: Completed, Estimated PCD: 2012-03-19
Clinical trial
A Randomized Phase II Study of Two Different Schedules of RAD001C in Patients With Recurrent/Metastatic Breast CancerStatus: Completed, Estimated PCD: 2008-07-22
Clinical trial
A Phase III Study of Gemcitabine Plus Capecitabine (GEMCAP) Versus Gemcitabine Alone in Advanced Biliary CancerStatus: Terminated, Estimated PCD: 2010-05-11
Clinical trial
A Randomized Phase II Study of OGX-011 in Combination With Docetaxel and Prednisone or Docetaxel and Prednisone Alone in Patients With Metastatic Hormone Refractory Prostate CancerStatus: Completed, Estimated PCD: 2007-11-08
Clinical trial
A Phase III Randomized Study of Brivanib Alaninate (BMS-582664) in Combination With Cetuximab (Erbitux®) Versus Placebo in Combination With Cetuximab (Erbitux®) in Patients With K-RAS Wild Type Tumors Previously Treated With Combination Chemotherapy for Metastatic Colorectal CarcinomaStatus: Completed, Estimated PCD: 2011-09-06
Clinical trial
A Phase II Study of a Second Generation Clusterin Antisense Oligonucleotide (OGX-011) in Combination With Docetaxel in Advanced Breast CancerStatus: Completed, Estimated PCD: 2007-02-23
Clinical trial
A Phase I Study Of Combination Neoadjuvant Hormone Therapy And Weekly OGX-011 (Clusterin Antisense Oligonucleotide) Prior To Radical Prostatectomy In Patients With Localized Prostate CancerStatus: Completed, Estimated PCD: 2004-09-23
Clinical trial
A Phase I Study of a Second Generation Clusterin Antisense Oligonucleotide (OGX-011) in Combination With DocetaxelStatus: Completed, Estimated PCD: 2006-03-09
Clinical trial
A Phase II Study of Bortezomib and Gemcitabine in Patients With Relapsed Mantle Cell LymphomaStatus: Completed, Estimated PCD: 2009-04-21
Clinical trial
A Phase I Study of Temozolomide and RAD001C in Patients With Malignant Glioblastoma MultiformeStatus: Completed, Estimated PCD: 2010-09-24
Clinical trial
A Phase I-II Trial of MK-0646, a Monoclonal Antibody Against Insulin-Like Growth Factor-1 Receptor, in Combination With Etoposide and Cisplatin in Extensive Stage Small Cell Lung CancerStatus: Completed, Estimated PCD: 2012-03-15
Clinical trial
A Multi-Centre Phase II Trial Investigating the Efficacy and Tolerability of Bortezomib Added to Cyclophosphamide, Vincristine, Prednisone, and Rituximab (BCVP-R) for Patients With Advanced Stage Follicular Non-Hodgkin's Lymphoma Requiring Systemic First-Line TreatmentStatus: Completed, Estimated PCD: 2011-04-01
Clinical trial
A Phase II Study Of PS-341 (NSC 681239) In Patients With Untreated Or Relapsed Mantle Cell LymphomaStatus: Completed, Estimated PCD: 2005-07-21
Clinical trial
A Phase I/II Study of Sorafenib (BAY 43-9006) in Combination With Low Dose ARA-C (CYTARABINE) in Elderly Patients With AML or High-Risk MDSStatus: Completed, Estimated PCD: 2010-03-18
Clinical trial
A Phase I Study of AZD2281 in Combination With Irinotecan in Patients With Locally Advanced or Metastatic Incurable Colorectal CancerStatus: Completed, Estimated PCD: 2012-09-25
Clinical trial
Phase III Study Of Gemcitabine, Dexamethasone, And Cisplatin Compared To Dexamethasone, Cytarabine, And Cisplatin Plus/Minus Rituximab [(R)-GDP vs (R)-DHAP] As Salvage Chemotherapy For Patients With Relapsed Or Refractory Aggressive Histology Non-Hodgkin's Lymphoma Prior To Autologous Stem Cell Transplant And Followed By Maintenance Rituximab vs ObservationStatus: Completed, Estimated PCD: 2013-07-29
Clinical trial
A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration Resistant Prostate CancerStatus: Completed, Estimated PCD: 2015-01-13
Clinical trial
A Randomized Phase II Study of Interleukin-21 (rIL-21) Versus Dacarbazine (DTIC) in Patients With Metastatic or Recurrent MelanomaStatus: Completed, Estimated PCD: 2014-11-25
Abstract
Comparing the time toxicity of cancer treatments in the CCTG LY.12 trial.Org: University of Minnesota Masonic Cancer Center, Minneapolis, MN, Queen's University, Belfast, Princess Margaret - University Health Network, Canadian Cancer Trials Group, NCIC Clinical Trials Group,