Organization
Shanghai Zhongshan Hospital
48 clinical trials
Clinical trial
A Single-center, Double-blinded, Randomized, Placebo-controlled Trial to Evaluate the Effectiveness and Safety of Low-frequency Injection of HRS9531 in Control of Weight Regain in Obese Subjects With and Without DiabetesStatus: Active (not recruiting), Estimated PCD: 2025-06-30
Clinical trial
Efficacy and Safety of Sunvozertinib With Anlotinib in EGFR-TKIs Resistant EGFR-sensitive Mutated Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC): a Prospective, Single-arm, Phase II TrialStatus: Not yet recruiting, Estimated PCD: 2026-01-01
Clinical trial
Dose Escalation and Expansion Clinical Trial of Irinotecan Liposome Combined With Oxaliplatin and 5-FU/LV Plus Bevacizumab as First-line Treatment of Metastatic Colorectal CancerStatus: Recruiting, Estimated PCD: 2026-01-01
Clinical trial
Growth Hormone Replacement Therapy on Metabolic Effects in Patients With Fatty Liver Caused by Growth Hormone Deficiency After Pituitary GH Adenoma Surgery: A Monocentric, Prospective, Randomized, Parallel-controlled Clinical Study.Status: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
The Effect of Continuous Intravenous Infusion of Lidocaine on Postoperative Pulmonary Complications and Prognosis in Emergency Surgical Patients With Intra-abdominal InfectionStatus: Active (not recruiting), Estimated PCD: 2025-09-30
Clinical trial
Study of Combination Treatment Using Anlotinib and TQB2450 in Patients With Advanced Hepatocellular Carcinoma Who Failed Prior Immune Checkpoint Inhibitor Therapies: a Single Arm, Multicenter Clinical TrialStatus: Not yet recruiting, Estimated PCD: 2025-10-31
Clinical trial
Safety and Efficacy of Perioperative Efgartigimod Combined With Thymectomy for Thymoma and Myasthenia Gravis: A Prospective, Single-arm StudyStatus: Not yet recruiting, Estimated PCD: 2026-12-30
Clinical trial
Two Stage, Multi-center Trial of Candonilimab in Combination With LM-302 for Treatment of Patients With Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standard of Chemotherapy and PD1/PD-L1 AntibodyStatus: Recruiting, Estimated PCD: 2025-08-01
Clinical trial
B7-Family Score Predicts Clinical Outcome From Chemotherapy and Checkpoint Blockade for Patients With Urothelial CarcinomaStatus: Completed, Estimated PCD: 2020-08-25
Clinical trial
The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related Myocarditis: a Single-arm, Prospective, Phase 2 TrialStatus: Not yet recruiting, Estimated PCD: 2025-11-30
Clinical trial
Assessment of the Efficacy of Glucocorticoids in Improving Post-operative Organ Dysfunction in Patients With Acute Type A Aortic Dissection(GLAD): a Randomized Controlled TrialStatus: Completed, Estimated PCD: 2023-11-29
Clinical trial
Comparative Effectiveness of Nadroparin Versus Transjugular Intrahepatic Portosystemic Shunt in Cirrhotic Patients With Refractory Asymptomatic Portal Vein Thrombosis：a Multicenter, Randomized Controlled TrialStatus: Not yet recruiting, Estimated PCD: 2025-05-30
Clinical trial
A Phase Ib/II Clinical Trial to Evaluate the Efficacy and Safety of Surufatinib in Combination With KN046 and AG Regimen Chemotherapy for the First-Line Treatment of Unresectable Advanced Pancreatic CancerStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
The Combination of Pembrolizumab and Lenvatinib as Neoadjuvant Treatment for Hepatocellular Carcinoma Patients: a Single Arm Phase II StudyStatus: Active (not recruiting), Estimated PCD: 2023-12-15
Clinical trial
A Retrospective Study Comparing Interventional Therapy (TACE/HAIC) Combined With PD-1/PD-L1 Inhibitors and Anti-angiogenic Agents Versus PD-1/PD-L1 Inhibitors and Anti-angiogenic Agents Alone in the First-line Treatment of Intermediate and Advanced Hepatocellular Carcinoma Beyond up to SevenStatus: Not yet recruiting, Estimated PCD: 2024-08-01
Clinical trial
A Single-arm, Single-center, Prospective Clinical Study of the Efficacy and Safety of Chemotherapy Combined With Toripalimab in the Treatment of Advanced Biliary Tract CancerStatus: Completed, Estimated PCD: 2021-12-01
Clinical trial
IndObufen Versus asPirin After Coronary Drug-eluting Stent implantaTION in Elderly Patients With Acute Coronary SyndromeStatus: Not yet recruiting, Estimated PCD: 2026-05-31
Clinical trial
Efficacy and Safety of Oxycodone Hydrochloride and Remifentanil for Long-term Analgesia During Invasive Mechanical Ventilation in Postoperative Patients: A Pilot StudyStatus: Not yet recruiting, Estimated PCD: 2025-02-28
Clinical trial
The Efficacy and Safety of Second-line Zimberelimab and SIRIOX Chemotherapy for Patient With Previously AG Chemotherapy Treated Pancreatic Cancer: A Prospective, Single Arm, Phase II Clinical StudyStatus: Not yet recruiting, Estimated PCD: 2026-01-01
Clinical trial
Retrospective Research on Lung Cancer Patients Receiving Neoadjuvant Immunochemotherapy From Zhongshan Hospital Fudan University.Status: Completed, Estimated PCD: 2022-11-01
Clinical trial
Second-line Treatment With CAdonilimab and LEnvatinib for Unresectable HCC: A Single Arm, Multicenter, Phase II Trial. (SCALE)Status: Not yet recruiting, Estimated PCD: 2026-05-31
Clinical trial
The Consistency of Tracking Changes of Cardiac Output by Carotid Doppler Blood Flow and Thermodilution Technique in Cardiac Surgery PatientsStatus: Recruiting, Estimated PCD: 2026-12-31
Clinical trial
Evaluation of the Efficacy and Safety of Fecal Microbiota Transplantation for Parkinson's Disease Patients With ConstipationStatus: Not yet recruiting, Estimated PCD: 2026-05-31
Clinical trial
Chemoradiotherapy Combined With Slulimumab in the Treatment of First-line Intrahepatic Cholangiocarcinoma: Efficacy and Safety Evaluation of a Phase II Clinical StudyStatus: Not yet recruiting, Estimated PCD: 2026-12-31
Clinical trial
A Phase II Study of Neoadjuvant Transcatheter Arterial Chemoembolization（TACE）Plus PD-1 Antibody (Tislelizumab) in the Locally Advanced Stomach AdenocarcinomaStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
A Study to Evaluate GP Chemotherapy in Combination With Tislelizumab and Ociperlimab as First-line Treatment in Participants With Unresectable Advanced Biliary Tract Carcinoma (BTC)Status: Active (not recruiting), Estimated PCD: 2023-01-18
Clinical trial
Furmonertinib Mesylate Neoadjuvant Treatment of Resectable Stage Ⅱ-ⅢB Non-small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor（EGFR）Sensitive Mutation：a Prospective，Muliticenter，Open Label，Phase Ⅱ Single-arm StudyStatus: Not yet recruiting, Estimated PCD: 2024-08-01
Clinical trial
A Phase II Study to Evaluate the Safety and Efficacy of Sintilimab Combined With Nab-paclitaxel and Gemcitabine for Neoadjuvant and Adjuvant Therapy of Patients With Resectable and Borderline Resectable Pancreatic CancerStatus: Not yet recruiting, Estimated PCD: 2025-10-01
Clinical trial
A Single-arm, Multi-center, Phase II Study of Tislelizumab, Lenvatinib and GEMOX Transformation in the Treatment of Potentially Resectable, Locally Advanced Biliary Tract CancerStatus: Active (not recruiting), Estimated PCD: 2023-07-03
Clinical trial
Effect of Canagliflozin on Cardiac Microcirculation Function in Patients With Type 2 Diabetes Mellitus Complicated With Cardiovascular Risk FactorsStatus: Recruiting, Estimated PCD: 2024-01-01
Clinical trial
Effectiveness of Regimen Switch After Intensive Insulin Therapy in Hospitalized Patients With Type 2 DiabetesStatus: Recruiting, Estimated PCD: 2023-12-31
Clinical trial
Ciprofol Versus Propofol for Tracheal Intubation in ICU Patients: a Randomized Controlled Pilot StudyStatus: Not yet recruiting, Estimated PCD: 2026-05-30
Clinical trial
Study to Assess the Efficacy and Safety of iNCDSS Assisted Insulin Dosage Titration System on Glucose Control in Type 2 Diabetes Mellitus Patients : a Muticenter, Single-blind, Randomized Controlled StudyStatus: Completed, Estimated PCD: 2022-09-08
Clinical trial
Tislelizumab Plus Cetuximab and Irinotecan Comparing the Third-line Standard-of-care Selected by Researchers in the Treatment of Ras Wild-type Recurrent Refractory Metastatic Colorectal Cancer: A Multicenter, Randomized, Controlled Clinical TrialStatus: Recruiting, Estimated PCD: 2024-04-01
Clinical trial
A Single-center, Prospective Cohort Study of Neoadjuvant Anti-PD-1 Plus Chemotherapy in Locally Advanced Resectable Esophageal Squamous Cell CarcinomaStatus: Recruiting, Estimated PCD: 2023-12-01
Clinical trial
Adrenal Venous Sampling Under 1 mg Overnight Dexamethasone Suppression Test to Determine Subtype in Primary Aldosteronism，a Single Center, Randomized, Double Blended, Placebo Controlled Clinical TrailStatus: Completed, Estimated PCD: 2022-10-30
Clinical trial
Effect of Dapagliflozin for Remission of Type 2 Diabetes Mellitus: A Multicenter, Randomized, Placebo-Controlled TrialStatus: Active (not recruiting), Estimated PCD: 2023-01-30
Clinical trial
A Multicenter, Randomized, Double-blinded, Placebo-controlled Phase III Trial to Evaluate the Efficacy and Safety of Liraglutide on Body Weight Loss in Obese and Overweight PatientsStatus: Completed, Estimated PCD: 2022-12-31
Clinical trial
Phase I/II Study of Anti-PD-1/PD-L1 Antibodies Combined With S-adenosyl-methionine in Patients With Advanced-Stage Hepatocellular CarcinomaStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
Determine the Effects of Prone Positioning and Nitric Oxide in Adult COVID-19 Patients With ARDS by Electrical Impedance TomographyStatus: Recruiting, Estimated PCD: 2023-06-30
Clinical trial
PD-L1 Antibody Combined With CTLA-4 Antibody for Patients With Advanced Intrahepatic Cholangiocarcinoma Who Progressed After Standard Treatment: a Single-arm, Phase II Clinical StudyStatus: Recruiting, Estimated PCD: 2023-09-01
Clinical trial
Clinical Study of mRNA Personalized Tumor Vaccine Encoding Neonatal Antigen Combined With Sintilimab Injection Liver CancerStatus: Not yet recruiting, Estimated PCD: 2025-03-12
Clinical trial
Prediction for pCR After Neoadjuvant Immunotherapy Combined With Chemotherapy Using Single-Cell RNA Sequencing in Patients With Locally Advanced Esophageal Squamous Cell Carcinoma (ESCC) : A Single-Arm Phase II Clinical TrialStatus: Completed, Estimated PCD: 2023-09-30
Clinical trial
Prone Positioning Versus Prone Positioning and NO Inhalation in COVID-19 Associated Acute Respiratory Distress Syndrome.Status: Recruiting, Estimated PCD: 2023-12-01
Clinical trial
An Open-label, Single-arm Phase II Study to Evaluate the Efficacy and Safety of TST001 for Patients With CLDN18.2 Positive Previously Treated Unresectable Advanced or Metastatic Biliary Tract CancerStatus: Completed, Estimated PCD: 2023-05-06
Clinical trial
The Evaluation of the Effect of Dihydroartemisinin in Patients With Polycystic Ovary SyndromeStatus: Completed, Estimated PCD: 2023-03-23
Clinical trial
Therapeutic Efficacy of Dihydroartemisinin in Patients With Polycystic Ovary SyndromeStatus: Recruiting, Estimated PCD: 2025-03-01
Clinical trial
Synergistic Effects of PD-1 Antibody and Chemotherapy Followed by Surgery in Patients With Limited-metastatic Gastric or Gastroesophageal Adenocarcinoma: an Open-label, Single-center, Phase 2 Trial (ROSETTE Trial)Status: Not yet recruiting, Estimated PCD: 2027-07-01