Product
MDMA
Aliases
3,4-methylenedioxymethamphetamine, 3,4-Methylenedioxymethamphetamine, Full dose MDMA, Full Dose MDMA (125 mg), Low dose MDMA (5 other aliases)
22 clinical trials
20 indications
Indication
Posttraumatic Stress DisorderIndication
PTSDIndication
AnxietyIndication
Post-Traumatic Stress DisorderIndication
pharmacokineticsIndication
Alcohol Use DisorderIndication
Psilocybin-assisted TherapyIndication
MDMAIndication
LSDIndication
Social Anxiety DisorderIndication
HealthyIndication
FibromyalgiaIndication
SchizophreniaIndication
Social InteractionIndication
Stimulant UseIndication
Social BehaviorIndication
MotivationIndication
Stress DisordersIndication
Post-TraumaticIndication
Opioid Use DisorderClinical trial
A Randomized, Double-Blind, Active Placebo-Controlled Phase 2 Pilot Study of MDMA-assisted Psychotherapy in People With Chronic, Treatment-Resistant Posttraumatic Stress Disorder (PTSD)Status: Completed, Estimated PCD: 2016-04-07
Clinical trial
Phase II Clinical Trial Testing the Safety and Efficacy of 3,4-Methylenedioxymethamphetamine (MDMA)-Assisted Psychotherapy in Subjects With Chronic Posttraumatic Stress DisorderStatus: Completed, Estimated PCD: 2008-05-02
Clinical trial
A Randomized, Double-Blind, Placebo-Controlled Phase 2 Pilot Study of MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening IllnessStatus: Completed, Estimated PCD: 2017-04-25
Clinical trial
A Phase 1/2 Open-Label Treatment Development Study of Methylenedioxymethamphetamine (MDMA)-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic Posttraumatic Stress Disorder (PTSD)Status: Completed, Estimated PCD: 2017-12-16
Clinical trial
A Phase 1, Single Center, Open Label, Randomized Sequence, 2-period Cross-over Study to Determine the Effect of Food on the Relative Bioavailability of 3,4-methylenedioxymethamphetamine (MDMA) Oral Formulation in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-12-02
Clinical trial
MDMA-assisted Therapy in Twelve People With War and Terrorism-related Posttraumatic Stress Disorder (PTSD)Status: Terminated, Estimated PCD: 2009-03-01
Clinical trial
Randomized, Triple-Blind, Phase 2 Pilot Study Comparing 3 Different Doses of MDMA in Conjunction With Manualized Therapy in 24 Veterans, Firefighters and Police Officers With Chronic Posttraumatic Stress Disorder (PTSD)Status: Completed, Estimated PCD: 2015-06-04
Clinical trial
A Randomized Trial of MDMA-Assisted Cognitive-Behavioural Conjoint Therapy (CBCT) Versus CBCT in Dyads in Which One Member Has Posttraumatic Stress Disorder (PTSD)Status: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
A Phase 2 Open-Label Treatment Development Study of MDMA-Assisted Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder (PTSD)Status: Active (not recruiting), Estimated PCD: 2024-06-01
Clinical trial
An Open Label, Phase 2, Single-arm Pilot Study to Investigate the Safety and Preliminary Effectiveness of MDMA-assisted Therapy in Veterans With Co-occurring Alcohol Use Disorder and Post-traumatic Stress Disorder (AUD-PTSD)Status: Recruiting, Estimated PCD: 2025-01-21
Clinical trial
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy TrainingStatus: , Estimated PCD: 2029-06-01
Clinical trial
Social Anxiety MDMA-Assisted Therapy Investigation (SAMATI): A Randomized, Delayed Treatment Control Phase 2 Study of the Safety and Effectiveness of Manualized MDMA-Assisted Therapy for the Treatment of Social Anxiety DisorderStatus: Active (not recruiting), Estimated PCD: 2025-08-01
Clinical trial
Epigenetic Regulation of Stress-related Genes in Relation to MDMA-Assisted Psychotherapy Treatment for Post-Traumatic Stress DisorderStatus: Active (not recruiting), Estimated PCD: 2023-11-01
Clinical trial
Mapping the Influence of Drugs of Abuse on Risk and Reward Circuits - MDMAStatus: Recruiting, Estimated PCD: 2024-11-01
Clinical trial
A Pilot Study of MDMA-Assisted Massed Exposure Therapy for PTSD (MDMA PE)Status: Recruiting, Estimated PCD: 2025-12-01
Clinical trial
Hyperscan Neuroimaging to Reveal the Brain Mechanisms Supporting Analgesia Following MDMA-assisted Therapy for FibromyalgiaStatus: Not yet recruiting, Estimated PCD: 2026-03-01
Clinical trial
Tolerability of MDMA in SchizophreniaStatus: Not yet recruiting, Estimated PCD: 2025-03-01
Clinical trial
Effects of Familiarity on Prosocial Effects of MDMAStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
Acute Effects of 3,4-methylenedioxymethamphetamine (MDMA) With and Without a Booster Dose (MDMA-booster Study)Status: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social FunctionStatus: Completed, Estimated PCD: 2022-10-24
Clinical trial
The Effects of MDMA on Prefrontal and Amygdala Activation in Posttraumatic Stress DisorderStatus: Withdrawn, Estimated PCD: 2028-01-01
Clinical trial
MDMA-Assisted Therapy 6 to 12 Months After Childbirth for People With Co-occurring Opioid Use and Post Traumatic Stress DisordersStatus: Active (not recruiting), Estimated PCD: 2025-04-01