Indication
Healthy
1082 clinical trials
1162 products
14 drugs
Product
RLD2102Clinical trial
A Randomized, Open Label, Single Dose, Crossover Clinical Trial to Evaluate the Pharmacokinetic Characteristics and Safety After Administration of a Fixed-dose Combination Drug of HCP2303 and Co-administration of RLD2302 and RLD2102 in Healthy Volunteers Under Fed ConditionsStatus: Not yet recruiting, Estimated PCD: 2024-06-29
Product
HCP2303Product
BI 3031185Clinical trial
A Phase 1, Single and Multiple Ascending Dose and Food Effect Study of NEU-411 Administered Orally to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-05-31
Clinical trial
A Single-Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of LY3074828 in Healthy Chinese SubjectsStatus: Completed, Estimated PCD: 2020-12-11
Clinical trial
A Phase 1 Randomized, A Phase 1 Randomized, Placebo Controlled, Double Blind, Two Part, Single- and Multiple-Ascending-Dose Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenously Administered ABL301 in Healthy Adult ParticipantsStatus: Recruiting, Estimated PCD: 2025-01-01
Product
BI 1323495Clinical trial
A Non-randomised, Open-label Phase I Trial to Evaluate the Effect of BI 456906 at Different Dose Levels of Multiple Subcutaneous Doses in a Titration Scheme on the Single Dose Pharmacokinetics of a Combination of Ethinylestradiol and Levonorgestrel in Otherwise Healthy Women With Overweight/ObesityStatus: Recruiting, Estimated PCD: 2024-10-23
Product
CM310Product
LY3074828Product
LY3819469Product
ZanubrutinibClinical trial
A Phase I, Double Blind, Placebo Controlled, Multiple Oral Dose, Safety, Tolerability, and Pharmacokinetic Study of KBP-7072 in Healthy Male and Female SubjectsStatus: Completed, Estimated PCD: 2020-10-08
Product
LY3502970Clinical trial
A Single-Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of LY3074828 in Japanese and Caucasian Healthy SubjectsStatus: Completed, Estimated PCD: 2018-07-16
Clinical trial
Safety and Clinical Activity of Nivatrotamab, an Anti GD2×CD3 Bispecific Antibody, in Relapsed/Recurrent Metastatic Small-cell Lung Cancer An Open-label, Single-arm, Multicenter, Phase 1/2 TrialStatus: Terminated, Estimated PCD: 2022-04-08
Clinical trial
A Randomized Clinical Trial to Investigate Salivary Flow and pH Following Use of Essential-Oil Containing MouthwashesStatus: Completed, Estimated PCD: 2023-11-16
Clinical trial
A Three-Part, Randomized, Double-Blind (Part A) and Open-Label (Part B and Part C), Multi-Dose, Phase 1 Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenous LY3938577 in Healthy Participants and Participants With Type 1 Diabetes MellitusStatus: Not yet recruiting, Estimated PCD: 2025-02-17
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, IMMUNOGENICITY AND PHARMACOKINETICS FOLLOWING SINGLE INTRAVENOUS DOSE OF PF-06823859 IN JAPANESE HEALTHY PARTICIPANTSStatus: Completed, Estimated PCD: 2022-03-27
Clinical trial
A Phase Ic, Randomized, Double-blind, Placebo-controlled, Multiple Dose-Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HB0034 in Adult Healthy Subjects.Status: Completed, Estimated PCD: 2023-06-09
Clinical trial
A Randomized, Placebo Controlled, Double-blind, Double-dummy Three-way Cross Over Trial to Investigate the Effect of BI 409306, BI 425809 and Lamotrigine on Ketamine-induced Cognitive Deficits in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-08-01
Product
KBP-5074Clinical trial
A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-CYC065 Following a Single Oral Dose in Healthy Male SubjectsStatus: Active (not recruiting), Estimated PCD: 2023-03-04
Product
BT-600Product
Glucophage XRClinical trial
Pharmacokinetics, Safety, and Tolerability of a Solution Formulation of LY3298176 in Healthy SubjectsStatus: Completed, Estimated PCD: 2018-12-27
Clinical trial
An Open-label, 2-Part, Phase 1 Clinical Trial to Evaluate Drug Interactions When DA-8010 is Co-administered With Paroxetine or Mirabegron in Healthy AdultsStatus: Completed, Estimated PCD: 2023-11-07
Product
MirabegronProduct
TT-00420Clinical trial
Open, Randomised, Two-way Crossover Study to Assess the Effect of a High Fat, High Caloric Meal on the Pharmacokinetics of BI 409306, Followed by a Fixed Sequence Period to Investigate the Pharmacokinetics of BI 409306 After a Single Oral Dose Given at Bed Time in Healthy Male and Female VolunteersStatus: Completed, Estimated PCD: 2014-10-31
Product
DA-8010Product
ReminylProduct
GLPG0492Product
ALXN2080Product
FluconazoleProduct
PonesimodClinical trial
Safety, Tolerability and Pharmacokinetics of Single Rising Intravenous Dose and Single Subcutaneous Dose of BI 655130 in Healthy Japanese Male Volunteers (Double-blind, Randomised, Placebo-controlled Design).Status: Completed, Estimated PCD: 2018-01-04
Product
IVX-241Product
BI 1815368Product
esomeprazoleProduct
CaffeineProduct
Liposomal BupivacaineClinical trial
A Phase 1, Double-Blind, Active- and Placebo-Controlled Dose Escalation Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupivacaine 13.3 Administered Via a Single Intrathecal Injection to Healthy VolunteersStatus: Recruiting, Estimated PCD: 2024-07-30
Product
PF-07817883Clinical trial
Effect of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 474121 in Healthy Male Subjects (an Open-label, Two-period Fixed Sequence Design Study)Status: Completed, Estimated PCD: 2021-04-01
Product
ItraconazoleClinical trial
A Phase 1, Single-Dose Study to Assess the Relative Bioavailability and Tolerability of Subcutaneous Peresolimab Test Formulations in Healthy ParticipantsStatus: Completed, Estimated PCD: 2024-01-11
Clinical trial
A Phase 1, Multicenter, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Hepatic Function and Participants With Mild, Moderate, or Severe Hepatic ImpairmentStatus: Recruiting, Estimated PCD: 2024-07-01
Product
ListerineProduct
[14C]-LY3871801Product
PF-07209326Product
LY3876602Product
DextroseProduct
LTG-001Clinical trial
A Phase 1, Randomized, Open-label, Parallel-group, Single- and Multiple-dose Study to Characterize Pharmacokinetics, Pharmacodynamics and Safety and Tolerability of JNJ-70033093 (BMS-986177) in Healthy Chinese Adult SubjectsStatus: Completed, Estimated PCD: 2021-12-04
Clinical trial
A Phase 1, First-in-Human, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Escalating Single and Multiple Doses of ENC1018 in Healthy Adult SubjectsStatus: Not yet recruiting, Estimated PCD: 2024-08-20
Clinical trial
A Safety, Tolerability, and Pharmacokinetic Study of Injections of LY3074828 Solution Using Investigational 1-mL Pre-filled Syringes and Investigational 2-mL Autoinjector in Healthy SubjectsStatus: Completed, Estimated PCD: 2019-01-25
Product
LY3537982Product
CarbamazepineClinical trial
A Randomised, Double-blind, Placebo-controlled Trial for Establishing Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Efficacy of Multiple Subcutaneous Doses of BI 655064 in Healthy Volunteers and in Rheumatoid Arthritis Patients With Prior Inadequate Response to Methotrexate TherapyStatus: Completed, Estimated PCD: 2015-03-02
Product
ObicetrapibClinical trial
An Open-Label, Non-controlled Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of Single Escalating Doses of BCD-180 (JSC BIOCAD, Russia) in Healthy VolunteersStatus: Completed, Estimated PCD: 2023-09-30
Clinical trial
A Study to Investigate the Pharmacokinetic Drug-drug Interaction Following Oral Administration of Ethinylestradiol/Levonorgestrel (Microgynon®) and BI 409306 in Healthy Korean Premenopausal Female Subjects (an Open-label, Two-period, Fixed-sequence Study)Status: Completed, Estimated PCD: 2017-12-01
Clinical trial
Phase 1, Open-Label, Drug Interaction Study to Investigate the Effect of Single Dose Selpercatinib on the Pharmacokinetics of Rosuvastatin in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-10-31
Clinical trial
Bioequivalence of the BI 1015550 High Dose Formulation C2 and the BI 1015550 High Dose Formulation C1 (Phase 3 Formulation) Following Oral Administration in Healthy Subjects (an Open-label, Randomised, Single-dose, Two-way Crossover Trial)Status: Not yet recruiting, Estimated PCD: 2024-08-30
Product
PF-07328948Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PB2452 (Bentracimab) With and Without Ticagrelor Pretreatment in Chinese Healthy VolunteersStatus: Terminated, Estimated PCD: 2022-12-30
Clinical trial
A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics of XH-S003 After Single and Multiple Ascending Doses, Plus the Evaluation of Food Effects in Healthy VolunteersStatus: Recruiting, Estimated PCD: 2024-04-30
Clinical trial
A Relative Bioavailability Study to Compare the Pharmacokinetics of LY3437943 Administered Subcutaneously by a Test Device (Test Formulation) Versus Reference Device (Reference Formulation) in Healthy ParticipantsStatus: Completed, Estimated PCD: 2024-02-08
Product
BI 765845Product
AcetaminophenClinical trial
Relative Bioavailability, Safety, and Tolerability Following Subcutaneous Injection of Different Doses of BI 655130 and Different Injection Sites in Healthy Male and Female Subjects (a Single Dose, Mono-centric, Open-label Study in Matched-group Design).Status: Completed, Estimated PCD: 2019-06-03
Product
vepdegestrantProduct
Insulin degludecProduct
ALXN1820Clinical trial
A Phase 1, Open-Label, Two-Part Study of the Disposition and Absolute Bioavailability of [14C]-LY3473329 in Healthy Male ParticipantsStatus: Active (not recruiting), Estimated PCD: 2024-04-01
Product
BI 1810631Product
LY3473329Product
LasmiditanProduct
TP 3654Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Zonisamide Capsules (100 mg; Mylan) to Zonegran® Capsules (100 mg; Elan) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-01-01
Clinical trial
A Phase 1, Single Center, Randomized (2-Sequence), Single Blind, 3-Period Study Comparing the Safety, Tolerability, and Pharmacokinetics of Ecopipam Controlled Release Capsules With Ecopipam HCl Immediate Release Tablets in Male Adult VolunteersStatus: Completed, Estimated PCD: 2012-02-01
Product
Microgynon 30Clinical trial
Single-Dose Fed In Vivo Bioequivalence Study of Olmesartan Medoxomil Tablets (40 mg; Mylan) to Benicar® Tablets (40 mg; Sankyo) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-12-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Metoprolol Tartrate Tablets (100 mg; Mylan) and Lopressor® (100 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Clinical trial
Open Label Trial to Evaluate the Adhesion of TK-254RX in Healthy Volunteers.Status: Completed, Estimated PCD: 2023-11-09
Clinical trial
A Dose-block Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose, First-in-human, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics After Subcutaneous Administration of C1K in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-06-28
Clinical trial
A Multi-Part, Phase 1 Study With Randomized, Double-Blind, Sponsor-Open, Placebo-Controlled, Single- And Multiple-Dose Escalation To Evaluate The Safety, Tolerability, And Pharmacokinetics Of PF-07976016 In Healthy Adult ParticipantsStatus: Recruiting, Estimated PCD: 2024-09-05
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR OPEN, PLACEBO CONTROLLED, DOSE ESCALATING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE INTRAVENOUS AND MULTIPLE SUBCUTANEOUS AND INTRAVENOUS DOSES OF PF-07261271 IN HEALTHY PARTICIPANTSStatus: Completed, Estimated PCD: 2024-02-29
Product
IVX-A12Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled Study to Investigate Safety, Tolerability, and Pharmacokinetics With Single Intravenous Ascending Doses and Single and Multiple Subcutaneous Doses of LY3848575 in Healthy Participants, Including First-generation Japanese ParticipantsStatus: Completed, Estimated PCD: 2024-02-19
Product
LY3848575Clinical trial
Thorough QT Study to Evaluate the Effects of BI 409306 as Single Dose on Cardiac Safety Parameters in Healthy Male and Female Subjects. A Randomized, Placebo Controlled, Double-blind, Five-period Crossover Study With (Open-label) Moxifloxacin as Positive ControlStatus: Completed, Estimated PCD: 2019-09-06
Product
Sodium ChlorideProduct
BI 706321Product
LY3985297Clinical trial
A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase Ⅲ Clinical Study to Evaluate Efficacy and Safety of AYP-101 for the Reduction of Submental Fat in AdultsStatus: Recruiting, Estimated PCD: 2024-08-07
Clinical trial
Pharmacokinetics of LY3819469 Following Subcutaneous Dose in Participants With Renal Impairment Compared With Participants With Normal Renal FunctionStatus: Completed, Estimated PCD: 2024-01-09
Product
AspirinProduct
SisunatovirClinical trial
Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 1595043 (Single-blind, Partially Randomised, Placebo-controlled, Parallel (Sequential) Group Design) in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2021-03-19
Product
ZongertinibProduct
PRO-232Clinical trial
A Phase 1, Open-Label Study to Determine the Relative Bioavailability of LY3454738 in Healthy ParticipantsStatus: Active (not recruiting), Estimated PCD: 2024-05-02
Product
BI 1358894Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic Profiles Following Single and Multiple Doses and Food Effect of CS12192 Capsules in Healthy Adult Chinese SubjectsStatus: Completed, Estimated PCD: 2024-02-01
Product
TestosteroneProduct
BGF MDI HFAClinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Oral Doses of BI 1569912 (Single-blind, Partially Randomized Within Dose Groups, Placebo-controlled, Parallel Group Design) With an Optional Posology (Uptitration) Part (Single-blind, Partially Randomized Within Dose Groups, Placebo-controlled, Parallel Group Design) in Healthy Male SubjectsStatus: Recruiting, Estimated PCD: 2024-07-04
Product
KRP-A218Product
BGB-DXP593Product
bupropionProduct
BI 894416Product
TClinical trial
A Single and Multiple Ascending Dose Study to Assess the Safety,Tolerability, PK, PD, and Food Effect of HSK39297 in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-05-31
Clinical trial
Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BI 474121 in Healthy Japanese Male Subjects (Doubleblind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2021-11-11
Product
IBI311Clinical trial
An Open-Label, Single-Dose, Single-Period Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-Paxalisib in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2023-03-30
Clinical trial
A Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetic Profile of Single and Multiple Doses of KH607 Tablets in Chinese Healthy VolunteersStatus: Recruiting, Estimated PCD: 2024-10-30
Product
MetforminClinical trial
A Phase 1 Study to Evaluate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2024-02-05
Clinical trial
Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 894416 Versus Placebo in Healthy Male Japanese Subjects (Single-blind, Randomized, Placebo-controlled Within Dose Group)Status: Terminated, Estimated PCD: 2020-11-12
Product
JNJ-68179280Product
LY3209590Product
MT200605Product
[¹⁴C]-LOXO-783Product
LOXO-783Clinical trial
Bioequivalence of Three Different Tablet Formulations of 30 mg of Apremilast (EU-sourced Otezla® vs. US-sourced Otezla® vs. Japan-sourced Otezla®) Administered in Healthy Male and Female Subjects in the Fasted State as Well as (for EU-sourced Otezla® vs. US-sourced Otezla®) in the Fed State (an Open-label, Randomised, Single-dose, Five-period, Ten-sequence Crossover Study)Status: Terminated, Estimated PCD: 2021-08-18
Clinical trial
A Phase 1, Two-part, Open-label, Fixed-sequence Study to Evaluate the Effects of Multiple Doses of Itraconazole and Carbamazepine on the Single-dose Pharmacokinetics of LY3410738 in Healthy Adult SubjectsStatus: Terminated, Estimated PCD: 2022-04-12
Clinical trial
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Subcutaneous Doses of BI 3006337 in Healthy Male Subjects (Single-blind, Partially Randomised Within Dose Groups, Placebo-controlled, Parallel (Sequential) Group Design)Status: Completed, Estimated PCD: 2023-03-03
Product
SR1375Product
L04TD1Clinical trial
A PHASE 1, OPEN LABEL, FIXED SEQUENCE STUDY TO ESTIMATE THE EFFECT OF MULTIPLE DOSE PF-06650833 ON THE PHARMACOKINETICS OF SINGLE DOSE ORAL CONTRACEPTIVE STEROIDS IN HEALTHY FEMALE PARTICIPANTSStatus: Completed, Estimated PCD: 2021-12-16
Clinical trial
A Phase 1, Randomized, Double-Blind, Single-Dose and Repeat Single-Dose, Dose-Escalation Study to Determine the Safety, Tolerability, and Pharmacokinetics of CD388 Intramuscular or Subcutaneous Administration in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-10-27
Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of Subcutaneous ALXN1830 in Healthy ParticipantsStatus: Terminated, Estimated PCD: 2021-12-14
Product
HCTZClinical trial
A Phase 1 Study to Evaluate the Drug-Drug Interaction Between ABBV-CLS-7262, Rosuvastatin, and Digoxin Following Multiple Doses of ABBV-CLS-7262Status: Completed, Estimated PCD: 2023-05-08
Product
G03-52-01Clinical trial
A Phase 1, Single Center, Randomized, Controlled Platform Study Validating the Use of Candin as a Challenge Agent in Healthy Volunteers or Patients Given Concomitant Approved InterventionsStatus: Completed, Estimated PCD: 2022-11-02
Product
CandinClinical trial
A RANDOMIZED, PHASE 1, SINGLE-BLIND, MULTI-PERIOD STUDY TO INVESTIGATE THE PALATABILITY OF PF-07923568 ORAL SUSPENSION IN DIFFERENT LIQUID VEHICLES IN HEALTHY ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2023-09-20
Product
BI 1356225Product
SYR-472Clinical trial
A Parallel-group Treatment, Phase 1, Participant- and Investigator-Blind, Randomized Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Intravenous Dose of Donanemab Compared With Placebo in Healthy Chinese ParticipantsStatus: Completed, Estimated PCD: 2023-01-05
Clinical trial
A Randomized, Open, Parallel Phase I Clinical Study on the Comparison of Pharmacokinetics Characteristics of CM310 Recombinant Humanized Monoclonal Antibody Injection in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-03-30
Clinical trial
A Randomized, Open Label, Single Dose, 2-way Crossover Clinical Trial to Evaluate the Pharmacokinetic Characteristics and Safety Between After Administration of a Fixed-dose Combination Drug of HCP2001 and Co-administration of Each Component in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-11-27
Clinical trial
An Open-label Phase 1 Study to Evaluate PK/PD Drug-drug Interactions and Safety/Tolerability Between RLD2202 and RLD2203 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-10-25
Clinical trial
Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses and Multiple Oral Doses of BI 1569912 in Healthy Male Japanese Subjects (Single-blind, Partially Randomised Within Dose Groups, Placebo-controlled, Parallel-group Design)Status: Active (not recruiting), Estimated PCD: 2023-10-24
Clinical trial
A Single-Dose Study in Healthy Participants to Characterize Ramucirumab Pharmacokinetics and Investigate Injection Site Reactions Following an Intravenous Infusion or Subcutaneous Administration of RamucirumabStatus: Completed, Estimated PCD: 2021-05-09
Product
RLS-0071Clinical trial
A Randomized, Partial-Blind, Placebo and Positive-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses of HSK36273 in Healthy Subjects.Status: Completed, Estimated PCD: 2022-09-12
Product
MacitentanClinical trial
A Dual-center, Randomized, Double-blinded and Parallel-controlled Study to Assess the Pharmacokinetic, Pharmacodynamics, Safety and Immunogenicity of HS-20090 Injection and Xgeva® in Healthy AdultsStatus: Recruiting, Estimated PCD: 2024-04-05
Product
JanumetProduct
RSVpreF+qIRVProduct
qIRVProduct
HS-20090Clinical trial
A Single-center, Open-label, Randomized, Crossover Phase 1 Trial to Investigate Bioequivalence Between 5 × 10 mg Tablets and 2 × 25 mg Tablets of Daridorexant in Healthy Male and Female Japanese ParticipantsStatus: Completed, Estimated PCD: 2023-08-04
Product
DaridorexantProduct
DapagliflozinClinical trial
Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BI 730357 in Japanese Healthy Male Subjects (Double-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2019-04-26
Product
JiashenClinical trial
A Phase I, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, and PK of ASC11/RTV Tablets and Study to Evaluate the Effects of Food on the PK of ASC11/RTV Tablets in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2023-04-04
Clinical trial
Interventional, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study Part Investigating the Safety, Tolerability, and Pharmacokinetic and -Dynamic Properties of Lu AF90103 and a Double-Blind, Cross-Over Study Part Investigating the Safety Profile After Infusion of Lu AF90103 at Two Rates to Healthy MenStatus: Terminated, Estimated PCD: 2021-11-23
Clinical trial
A Phase 1, Open-label, Two-part Study to Investigate the Absorption, Metabolism, and Excretion, and the Absolute Bioavailability of [14C]-LOXO-292 in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2018-09-24
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO -CONTROLLED, FIRST-IN-HUMAN TRIAL TO EVALUATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF PF 06755347 AFTER SINGLE ASCENDING INTRAVENOUS AND SUBCUTANEOUS DOSING IN HEALTHY ADULT MALE PARTICIPANTS AND OPEN-LABEL AFTER SINGLE SUBCUTANEOUS DOSING IN MALE AND FEMALE PARTICIPANTS WITH PERSISTENT OR CHRONIC PRIMARY IMMUNE THROMBOCYTOPENIAStatus: Terminated, Estimated PCD: 2023-01-06
Product
ASAProduct
SumatriptanProduct
NEU-723Product
JP-1366Product
gp140 DPClinical trial
A Pharmacokinetic Study of Zavegepant Intranasal in Healthy Adults Comparing Conventional Venous Blood Sampling With Patient-Centric SamplingStatus: Completed, Estimated PCD: 2023-09-05
Clinical trial
A Phase I, Randomized, Open-label Study to Evaluate the Potential Pharmacokinetic Interactions Between D-0120 and Allopurinol in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-02-10
Clinical trial
A Single-Center, Open-label, Single-Arm Study to Evaluate the Effects of Repeat Doses of Subcutaneously Delivered Sumatriptan Via the Intraject System of Local Injection Site Signs in Healthy Adult Subjects.Status: Completed, Estimated PCD: 2007-12-01
Clinical trial
An Open-Label, Single-Dose Study to Evaluate the Pharmacokinetics of MCI-186 in Subjects With Mild or Moderate Renal Impairment Compared to Subjects With Normal Renal FunctionStatus: Completed, Estimated PCD: 2018-04-16
Clinical trial
A PhaseⅠRandomised, Double-blind, Placebo-controlled, Study to Evaluate the Safety, Tolerability, and Pharmacokinetics Characteristics of the Oral Topical Use of GB001 Recombinant Peptide Spray in Chinese Healthy Adult SubjectsStatus: Active (not recruiting), Estimated PCD: 2022-11-12
Clinical trial
A Single and Multiple Dose Study of Rodatristat Ethyl in Healthy Subjects to Evaluate the Effect of Food, and the Safety, Tolerability, and Pharmacokinetics of a Supratherapeutic Dose of Rodatristat EthylStatus: Completed, Estimated PCD: 2023-01-17
Clinical trial
A Phase I, Open-label Trial in Two Parallel Parts to Investigate Mass Balance, Metabolism, and Basic Pharmacokinetics of BI 1810631 (C-14) Administered as Oral Solution (Part A) and to Investigate Absolute Bioavailability of BI 1810631 Administered as Film-coated Tablet Together With an Intravenous Microtracer Dose of BI 1810631 (C-14) (Part B) in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2023-10-19
Product
GLS-5310Clinical trial
A PHASE 1 STUDY TO EVALUATE THE EFFECTS OF MULTIPLE DOSES OF LY3537982 ON THE SINGLE-DOSE PHARMACOKINETICS OF MIDAZOLAM, DIGOXIN, AND ROSUVASTATIN IN HEALTHY ADULT SUBJECTSStatus: Not yet recruiting, Estimated PCD: 2024-01-31
Clinical trial
An Open-label, Nonrandomized, Single-dose, Parallel-group, Safety, Tolerance, and Pharmacokinetic Study of LOXO-305 Administered to Fasted Renally Impaired Male and Female Subjects and Fasted Matched-control Healthy SubjectsStatus: Completed, Estimated PCD: 2021-06-04
Clinical trial
An Open, Single Dose Designed Clinical Study to Evaluate Safety and Pharmacokinetic/Pharmacodynamic Characteristics After Oral Administration of URC102 in Patients With Renal Impairment Under Fasted Conditions and Healthy Adult Volunteers Under Fasted and Fed ConditionsStatus: Completed, Estimated PCD: 2022-07-13
Product
Moderna mRNA-1273Clinical trial
A Phase 1 Study to Determine the Safety, Tolerability, and Pharmacokinetics of ALXN2050 in Healthy Participants of Japanese DescentStatus: Completed, Estimated PCD: 2021-09-07
Product
B1Product
TT-00920Product
RVP-001Clinical trial
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate A Range of Dose Levels of a Heterologous Prime-Boost Regimen of Ad26.ZEBOV and MVA-BN®-Filo in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2016-06-07
Product
TegoprazanClinical trial
Disposition of [14C]-Tirzepatide Following Subcutaneous Administration in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2020-10-02
Clinical trial
A Single-center, Randomized, Double-blind, Placebo-controlled, Dose-ascending Phase I Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of Sudapyridine (WX-081) Tablets in Healthy Chinese SubjectsStatus: Completed, Estimated PCD: 2020-07-02
Product
CT-P39Clinical trial
A Single-center, Open-label, Fixed-sequence Study to Investigate the Effect of Multiple-dose Itraconazole on the Pharmacokinetics of a Single Dose of 10 mg ACT-1004-1239 in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-10-20
Product
JNJ-64457744Product
Ad26.Mos4.HIVClinical trial
A Randomized, Double Blind, Three-arm, Parallel Group, Single Dose Comparative PK, PD, Safety and Immunogenicity Study Comparing ADL-018 With US-licensed XOLAIR and EU-Approved XOLAIR in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2023-02-21
Clinical trial
A Phase I, Single-center, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Tolerability of ILB-202 Administered Intravenously as Single Ascending Doses to Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-09-05
Clinical trial
A PHASE 1, OPEN-LABEL, SINGLE DOSE STUDY TO INVESTIGATE THE PHARMACOKINETICS, PHARMACODYNAMICS, SAFETY, AND TOLERABILITY OF PONSEGROMAB ADMINISTERED SUBCUTANEOUSLY IN HEALTHY ADULT CHINESE PARTICIPANTSStatus: Completed, Estimated PCD: 2023-07-07
Clinical trial
Phase 1, Randomised, Open-label, 3-way Crossover Study to Evaluate the Safety, Tolerability, Pharmacokinetics (With Food Effect), and Relative Bioavailability of NTP42:KVA4 Given as a Capsule, Compared With a Liquid, in Healthy VolunteersStatus: Recruiting, Estimated PCD: 2023-12-01
Product
PseudoephedrineClinical trial
A Randomized, Double-blind, Placebo-controlled Phase I Clinical Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Immunogenicity of CM326 Injection in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-03-01
Product
TP-05Clinical trial
A Phase 1, Randomized, Double-Blind, Single Ascending Dose Study to Determine the Safety, Tolerability, and Pharmacokinetics of CD388 Subcutaneous Administration in Healthy Japanese SubjectsStatus: Completed, Estimated PCD: 2023-07-14
Clinical trial
A Phase 1, Single-Ascending-Dose, Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3410738 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2021-08-04
Product
Oritavancin DiphosphateClinical trial
A Phase 1, Randomized, Blinded, Placebo Controlled, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of PRS 220 Administered by Oral Inhalation in Healthy Subjects.Status: Completed, Estimated PCD: 2023-08-11
Clinical trial
Phase Ib Evaluation of the Safety and Tolerability and Effect on Midazolam Metabolism of the Administration of Multiple Rising Doses of BI 730357 to Healthy VolunteersStatus: Completed, Estimated PCD: 2018-08-24
Clinical trial
A Study to Compare the Pharmacokinetics of Tirzepatide Administered Subcutaneously by an Autoinjector Versus Prefilled Syringe in Healthy SubjectsStatus: Completed, Estimated PCD: 2019-12-16
Clinical trial
A PHASE 1, OPEN-LABEL, FIXED-SEQUENCE STUDY TO ESTIMATE THE EFFECT OF PF-07081532 ADMINISTRATION ON THE SINGLE-DOSE PHARMACOKINETICS OF DABIGATRAN AND ROSUVASTATIN IN OVERWEIGHT OR OBESE ADULT PARTICIPANTSStatus: Terminated, Estimated PCD: 2023-09-11
Product
LipopolysaccharideClinical trial
A Randomized, Placebo-controlled, Double-blind, Single Ascending Dose Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-67835989 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-05-18
Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Pharmacokinetics and Safety of Subcutaneous CSL324 in Healthy Japanese and White SubjectsStatus: Completed, Estimated PCD: 2021-11-17
Clinical trial
A Multi-center, Randomized, Double-blind, Placebo-controlled Phase 3 Efficacy Study of a Heterologous Vaccine Regimen of Ad26.Mos4.HIV and Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals Who Have Sex With Cis-gender Men and/or Transgender IndividualsStatus: Completed, Estimated PCD: 2023-08-10
Product
Coumadin®Clinical trial
Effect of Rifampicin on the Pharmacokinetics of a Single Oral Dose of BI 894416 in Healthy Male Subjects (an Open-label, One-way Crossover Study)Status: Completed, Estimated PCD: 2019-10-17
Clinical trial
A PHASE 1, OPEN-LABEL, SINGLE SUBCUTANEOUS DOSE STUDY TO EVALUATE THE PHARMACOKINETICS, SAFETY AND TOLERABILITY OF LYOPHILIZED FORMULATION OF RECIFERCEPT IN HEALTHY CHINESE PARTICIPANTSStatus: Withdrawn, Estimated PCD: 2023-12-12
Clinical trial
An Open-label, Randomized, Cross-over Study With 2 Treatments (Fasting and After Meals), 3 Periods, 2 Sequences, and an Adaptive, Two-stage Design to Evaluate the Effect of Food Intake on the Bioavailability of XC8, Film-coated Tablets, 10 mg at a Single Dose of 20 mg in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-02-03
Product
ManitolClinical trial
A Single-center, Open-label Study to Investigate the Effect of Single- and Multiple-dose Daridorexant on the Pharmacokinetics of Midazolam and Its Metabolite 1-hydroxymidazolam, and the Effect of Single-dose Daridorexant on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-09-23
Product
CimetidineClinical trial
A Double-Blind, Randomized, Placebo-Controlled, Age Descending and Expansion Phase 2 Study to Investigate the Safety and Immunogenicity of a Tetravalent Chimeric Dengue Vaccine in Healthy Volunteers Between the Ages of 1.5 - 45 YearsStatus: Completed, Estimated PCD: 2016-04-01
Clinical trial
A Phase 1, Randomized, Double-Blinded, Single-Dose Escalation Study Followed by a Multiple-Dose Escalation Study of SKL24741 in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-10-27
Clinical trial
Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of CM310 Recombinant Humanized Monoclonal Antibody Injection in Healthy SubjectsStatus: Completed, Estimated PCD: 2020-01-13
Clinical trial
A Phase 1, Randomized, Placebo-controlled, Participant- and Investigator-blind, Single-dose Study of the Pharmacokinetics of LY3471851 Following Subcutaneous Dosing of LY3471851 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-02-23
Product
LevocetirizineClinical trial
A Phase 1, Randomized, Open-Label, Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous LY3471851 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-07-06
Clinical trial
A Phase 1 FIH, Randomized, Double Blind, Placebo Controlled, SAD/MAD Study to Assess Safety, Tolerability, PK/PD and Food Effect of Trichomylin in Healthy Adult Participants and Preliminary Efficacy in Management of Chronic OA PainStatus: Completed, Estimated PCD: 2022-02-18
Clinical trial
Effect of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 1584862 in Healthy Male Subjects (an Open-label, Two-period, Fixed-sequence Design Study)Status: Completed, Estimated PCD: 2023-11-10
Product
TR-01-XRClinical trial
A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-LY3871801 in Healthy Male ParticipantsStatus: Completed, Estimated PCD: 2023-11-03
Clinical trial
The Impact of the Vasodilator, Sildenafil, on the Pulmonary Circulation During Exercise in Healthy Trained and Untrained HumansStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
A Double-blind, Placebo-controlled Investigation of Inter-individual Variability in Pharmacologic Response to Non-steroidal Anti-inflammatory DrugsStatus: Terminated, Estimated PCD: 2022-09-01
Product
Anthrax Vaccine AdsorbedClinical trial
Diverse Ancestry Study in Inflammatory Bowel DiseaseStatus: Recruiting, Estimated PCD: 2027-05-01
Product
BG136Clinical trial
Single-Dose Fed Bioequivalence Study of Verapamil HCl Extended-Release Capsules (300 mg; Mylan) and Verelan® PM Extended-Release Capsules (300 mg; Schwarz) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-01-01
Clinical trial
Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane in Patients With Breast CancerStatus: Recruiting, Estimated PCD: 2024-10-31
Product
[11C]MeDASProduct
MethylphenidateClinical trial
To Determine the Effect of Endogenous GLP-1 Secretion on Islet Function in People With and Without Type 2 DiabetesStatus: Completed, Estimated PCD: 2022-12-15
Clinical trial
Single-Center, Open, Randomized, Single-Dose, Completely Repeated Crossover Bioequivalence Study to Evaluate the Effects of the Test/Reference Preparation, Entacapone,Levodopa and Carbidopa Tablets (II) in the Postprandial State in Healthy Adult SubjectsStatus: Not yet recruiting, Estimated PCD: 2024-01-04
Clinical trial
CIRcadian Rhythms and CortisoL. Effects on Substrate Metabolism and Clock Gene Expression and FunctioningStatus: Recruiting, Estimated PCD: 2024-03-01
Clinical trial
LSD Base and LSD Tartrate Bioequivalence and Bioavailability in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-10-11
Clinical trial
Developing an Approach to Perturbation of Human Small Intestinal and Colonic Permeability in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2024-01-23
Product
[18F]FluortrioprideProduct
Active PregnenoloneProduct
GlimepirideProduct
AmarylClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Olanzapine Tablets (5 mg; Mylan) and Zyprexa® Tablets (5 mg; Eli Lilly) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-07-01
Product
ZyprexaClinical trial
Vasopressin Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking StudyStatus: Recruiting, Estimated PCD: 2025-06-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Finasteride Tablets (5 mg; Mylan) to Proscar® Tablets (5 mg; Merck) in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2004-10-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study Metformin Hydrochloride ER Tablets (500 mg; Mylan) and Glucophage® XR (500 mg; Bristol-Myers Squibb) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-11-01
Clinical trial
Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive DeclineStatus: Recruiting, Estimated PCD: 2026-12-31
Product
LSDClinical trial
The Effect of Food on the Pharmacokinetics of BI 1015550 (Formulation C2) Following Single Oral Dose Administration in Healthy Subjects (an Open-label, Randomised, Single-dose, Two-period, Two-sequence Crossover Design)Status: Not yet recruiting, Estimated PCD: 2024-07-24
Clinical trial
Drone Biological Samples Transport Evaluation Compared to Walking in CHU CAEN NORMANDIEStatus: Completed, Estimated PCD: 2023-08-27
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Cilostazol Tablets (100 mg; Mylan) and Pletal® Tablets(100 mg; Otsuka) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-05-01
Product
CilostazolProduct
PletalClinical trial
Exploratory Study of the Impact of Lactobacillus Rhamnosus GG on Proton Pump Inhibitor-Induced Gut DysbiosisStatus: Recruiting, Estimated PCD: 2024-12-01
Clinical trial
The Effects of Nicotinamide Riboside Supplementation on Nicotinamide Adenine Dinucleotide (NAD+/NADH) Ratio and BioenergeticsStatus: Terminated, Estimated PCD: 2022-09-30
Product
Loxapine SuccinateProduct
Levothyroxine Sodium TabletsProduct
ProvigilProduct
GB002Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of SPY001-001 in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2025-08-02
Clinical trial
The Effects of Oxytocin on Social Touch: an fNIRS-based StudyStatus: Completed, Estimated PCD: 2022-03-01
Product
DoxycyclineClinical trial
The Objective of This Study Was to Investigate the Bioequivalence of Mylan's Escitalopram Oxalate 20 mg Tablets to Forest's Lexapro® 20 mg Tablets Following a Single, Oral 20 mg (1 x 20 mg) Dose Administered Under Fasting Conditions.Status: Completed, Estimated PCD: 2004-10-01
Product
LexaproClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Meloxicam Tablets (15 mg; Mylan) and Mobic® Tablets (15 mg; Boehringer Ingelheim) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-09-01
Product
IvermectinProduct
Paroxetine HydrochlorideProduct
Paxil CR TabletsClinical trial
Single-Dose Fed Bioequivalence Study of Propranolol Hydrochloride Extended-Release Capsules (160 mg; Mylan) and Inderal® LA Capsules (160 mg; Wyeth) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-10-01
Product
Glimepiride TabletsProduct
Skin auto-fluorescenceProduct
Valacyclovir HydrochlorideClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Alprazolam Extended-Release Tablets (1 mg; Mylan) to Xanax XR Tablets (1 mg; Pharmacia & Upjohn) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-01-01
Product
Anagrelide HydrochlorideProduct
AgrylinClinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Day Dose Study To Assess The Safety And Tolerability Of JNJ-72537634 In Healthy ParticipantsStatus: Completed, Estimated PCD: 2020-02-10
Clinical trial
Sex Disparities in Hypoxic Vasodilation and Impact of ObesityStatus: Recruiting, Estimated PCD: 2025-07-01
Product
PiperaquineClinical trial
Single-Dose Fasting In-Vivo Bioequivalence Study of Hydrochlorothiazide Tablets (50 mg; Mylan) to Hydrochlorothiazide Tablets (50 mg; Ivax) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-10-01
Product
NitrofurantoinProduct
MacrobidProduct
THB335Clinical trial
A Bioequivalence Study of Subcutaneous Injections of Citrate-Free Mirikizumab Solution Using a 1-mL Autoinjector and an Investigational 2-mL Autoinjector in Healthy ParticipantsStatus: Not yet recruiting, Estimated PCD: 2024-11-01
Clinical trial
Randomized, 2-Way Crossover, Bioequivalence Study of Galantamine 4 mg Tablet and Reminyl Following a 4 mg Dose in Healthy Subjects Under Fasting ConditionsStatus: Completed, Estimated PCD: 2004-12-01
Clinical trial
A Randomized, Open/Double-blind, Placebo-controlled Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of CM313 in Healthy Subjects With Single Subcutaneous Injection/Intravenous InfusionStatus: Not yet recruiting, Estimated PCD: 2025-04-30
Clinical trial
Phase 1 Clinical Trial to Explore Pharmacokinetics, Pharmacodynamics and Safety of Tegoprazan 12.5 mg After Oral Administration in Healthy SubjectsStatus: , Estimated PCD: 2024-07-31
Product
BAP5191Product
HCP2201Product
RLD2206Product
T2Product
TafamidisClinical trial
A Phase I, Open-label, Two-part Study of the Absorption, Metabolism, Excretion, and the Absolute Bioavailability of [14C]-LOXO-305 in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2020-11-06
Clinical trial
Study Evaluating the Effects of a Single Oritavancin Infusion on Cytochrome P450 (CYP) 1A2, CYP2C9, CYP2C19, CYP2D6, CYP3A, N-Acetyltransferase-2, and Xanthine Oxidase Activities in Healthy Adults Using the Cooperstown 5 + 1 CocktailStatus: Completed, Estimated PCD: 2013-03-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Valacyclovir Hydrochloride Tablets (1000 mg; Mylan) to Valtrex® Tablets (1000 mg; GlaxoSmithKline) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-05-01
Product
Hemay005Product
IL-YANG FLU VaccineProduct
HSK39297Clinical trial
A Partially Randomized, Sequential Cohort, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Subcutaneous Ravulizumab Coadministered With rHuPH20 in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2019-05-21
Clinical trial
A Double-Blind, Randomized, Placebo-Controlled Study to Assess the Safety, Tolerability, and Pharmacodynamics of SYNB8802 in Healthy Volunteers and in Patients With Enteric HyperoxaluriaStatus: Completed, Estimated PCD: 2023-01-17
Clinical trial
A Phase I, Open Label, Dose Escalation Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Intramuscular Injections of Letrozole LEBE at Different Strengths in Voluntary Healthy Post-Menopausal Women.Status: Recruiting, Estimated PCD: 2025-01-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Olanzapine Tablets (20 mg; Mylan) and Zyprexa® Tablets (20 mg; Eli Lilly) in Healthy VolunteersStatus: , Estimated PCD: 2003-05-01
Clinical trial
Exploratory Pilot Study to Evaluate the Pharmacokinetic Profile of MagaldrateStatus: Completed, Estimated PCD: 2024-01-15
Product
PF-07976016Product
14C-BI 409306Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single-center, Single and Multiple Ascending Oral Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of FP-020 in Healthy VolunteersStatus: Not yet recruiting, Estimated PCD: 2024-09-30
Product
MAD_placeboClinical trial
A Single-ascending and Multiple-ascending Dose Study of LY3971297 in Healthy Participants and Participants With Obesity and HypertensionStatus: Recruiting, Estimated PCD: 2024-10-02
Product
ALXN2050Clinical trial
Pilot Evaluation of the Effect of Application Procedure on the Antimicrobial Effects of an Aqueous CHG and a Traditional Iodophor Scrub PaintStatus: Completed, Estimated PCD: 2008-02-01
Product
LY3857210Clinical trial
A Bioequivalence Study to Compare the Pharmacokinetics of Two Betrixaban FormulationsStatus: Completed, Estimated PCD: 2015-11-01
Clinical trial
A Randomized, Double-blind, Placebo-controlled, Single Ascending-Dose Phase Ia Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of STSA-1201 Injection in Healthy SubjectsStatus: Completed, Estimated PCD: 2024-03-14
Clinical trial
Randomised, Crossover Bioavailability Clinical Trial of Oral Minoxidil 1 MG, After Single and Multiple Dose Administration to Healthy Volunteers Under Fasting Conditions.Status: , Estimated PCD: 2024-04-01
Product
GleptometClinical trial
Investigation of Mutual Pharmacokinetic Interactions of Digoxin, Furosemide, Metformin, and Rosuvastatin Given All Together as a Probe Cocktail for Key Drug Transporters (an Open-label, Randomised, Single-dose, Five-way Crossover Study)Status: Completed, Estimated PCD: 2016-11-11
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LPM3480392Clinical trial
Phase Ia Study to Evaluate the Tolerability, Safety, Pharmacokinetics, Preliminary Pharmacodynamics, and Immunogenicity of Single-dose JYB1904 in Healthy Chinese SubjectsStatus: Completed, Estimated PCD: 2023-01-10
Product
CG-SpikeDownClinical trial
A Randomized, Open Label, Single Dose, 4-period Replicate Crossover Clinical Trial to Evaluate the Pharmacokinetic Characteristics and Safety After Administration of a Fixed-dose Combination Drug of HCP2202 and Co-administration of RLD2202 and RLD2203 in Healthy Volunteers Under Fed ConditionsStatus: Completed, Estimated PCD: 2022-12-22
Clinical trial
Single-center, Randomized, Double-blind, Single-dose, 3-way Crossover Study to Compare the Effects of Daridorexant and Placebo on Postural Stability, the Auditory Awakening Threshold, and Cognitive Function in the Middle-of-the-night Following Evening Administration to Healthy Adult and Elderly SubjectsStatus: Completed, Estimated PCD: 2023-04-25
Clinical trial
A Randomized, Double-blind, Placebo-controlled Phase 1/2a Study for Safety and Immunogenicity Evaluations for Regimen Selection of Ad26.RSV.preF and/or RSV preF Protein Combinations Followed by Expanded Safety Evaluation in Adults Aged 60 Years and OlderStatus: Completed, Estimated PCD: 2022-05-16
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RSV preF ProteinClinical trial
A Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Phase 1 Clinical Trial to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect After the Oral Administration of NXC736 in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-11-01
Clinical trial
A Phase 1 Study to Evaluate the Effect of Food on the LY3537982 Pharmacokinetics in Health Adult SubjectsStatus: Completed, Estimated PCD: 2023-06-17
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[14C]-ALXN2050Product
Mirfenacin MRProduct
PF-07081532Product
Blood collectionClinical trial
A Phase I, Open-label Trial to Investigate Metabolism, Pharmacokinetics (Following a Mass Balance Design) and Absolute Bioavailability of BI 690517 (C-14) After Oral and Intravenous Administration in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-11-17
Product
MethotrexateProduct
Povidone iodineClinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Regeneron Anti-SARS-CoV-2 Monoclonal Antibody/Ies in Adult Healthy VolunteersStatus: Completed, Estimated PCD: 2023-01-26
Product
Alogliptin BenzoateProduct
HC-ERClinical trial
An Open-label, Parallel-group Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Cenerimod After Single-dose Administration in Subjects With Hepatic Impairment and in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-03-29
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FB-001Product
Measles Rubella VaccineProduct
L04RD1Product
IFN-β inhibitorProduct
ABX1100Product
PF-06264006Product
MIB 626Product
DextromethorphanClinical trial
A Phase I, Open-label, Two-part Study of the Absorption, Metabolism, Excretion, and the Absolute Bioavailability of [14C]-LY3537982 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2023-08-10
Product
[¹⁴C]-LY3537982Clinical trial
An Open-label, Crossover Study to Assess the Pharmacokinetics, Safety, and Tolerability of Various XW10172 Oral Immediate- and Modified-release Formulations in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2021-12-14
Clinical trial
A Single-dose, Open-label, Randomized, Two-treatment, Two-period, Crossover Study in Healthy Subjects to Assess the Bioequivalence of the Newly Formulated Tylenol® Tablet (Acetaminophen) to the Tylenol® 8H ER Tablet (Acetaminophen) Under Fed ConditionsStatus: Completed, Estimated PCD: 2020-01-16
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JNJ-63733657Clinical trial
A Three-Part Phase 1 Study to Evaluate the Potential Drug Interactions Between ALXN2050 and Cyclosporine, Tacrolimus, and Mycophenolate Mofetil in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2022-03-21
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MMFClinical trial
A Randomized, Open-label, Single-dose, Two-sequence, Two-period, Crossover Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of L04TD2 and L04RD1 in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2022-11-01
Product
UPB-101Product
DR10624Clinical trial
A Phase 1, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single-and-Multiple-Ascending Subcutaneous Doses of DR10624Status: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
A Bioequivalence Study to Compare the Pharmacokinetics of Tirzepatide Administered Subcutaneously by a Test Device (Test Formulation) Versus Reference Device (Reference Formulation) in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-07-17
Clinical trial
A Phase I, First-in-Human, Randomized, Double-Blind, Placebo-Controlled Trial of Single and Multiple Ascending Doses of M5717 to Assess the Safety, Tolerability and Pharmacokinetic Profile of Oral Doses, and to Assess the Antimalarial Activity of M5717 Against Plasmodium Falciparum in Healthy Male and Female Adult SubjectsStatus: Completed, Estimated PCD: 2019-06-14
Clinical trial
A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Immunogenicity of a Repeat Dose of G03-52-01 in Adult SubjectsStatus: Active (not recruiting), Estimated PCD: 2024-12-03
Clinical trial
An Open-label, Randomized, Two-way Crossover Trial of the Effect of a High-Fat Meal on the Pharmacokinetics of Oral Tosedostat (CHR 2797) in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2012-07-01
Product
ILB-202Clinical trial
Safety, Tolerability and Pharmacokinetics of Multiple Rising Oral Doses of BI 1819479 in Healthy Female Subjects of Non-childbearing Potential (Double-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2023-08-02
Product
TetrahydrouridineClinical trial
Phase 1 Assessment of Pharmacokinetics and Pharmacodynamics of Two Epoetin Alfa, Human Recombinant Epoetin (Blau Farmacêutica) and Eprex (Janssen-Cilag), After Single Dose, Intravenous Administration in Healthy Subjects: a Randomized Crossover Study.Status: Completed, Estimated PCD: 2013-10-31
Clinical trial
Pharmacodynamics Study of Enoxalow, Produced by Blau Farmacêutica S/A, Compared to Clexane, Produced by Sanofi-Aventis Farmacêutica Ltda, in Healthy Subjects After Intravenous Administration.Status: Completed, Estimated PCD: 2013-10-31
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PPSV23Clinical trial
A Single-Dose, Open-Label, Parallel-Group, Multi-Center Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Lazertinib (JNJ-73841937)Status: Completed, Estimated PCD: 2022-07-11
Product
EntecavirProduct
Dimethyltryptamin & HarmineClinical trial
A Randomized, Double-blind, Vehicle-controlled, Parallel Group, Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TDM-180935 Following Topical Administration in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2023-08-18
Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of a Regeneron Anti-SARS-CoV-2 Monoclonal Antibody (a COVID-19 Therapeutic) in Adult Healthy VolunteersStatus: Completed, Estimated PCD: 2023-05-30
Clinical trial
A Phase 1, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Subcutaneous Dose of NKTR-358 in Healthy VolunteersStatus: Completed, Estimated PCD: 2019-01-20
Clinical trial
A Phase 1, Double-blind, Randomized, Placebo-controlled, Dose-escalation, Pharmacokinetic Study of Single and Multiple Oral Dosing of HEC53856, A Novel HIF-PHD Inhibitor, in Healthy Non-elderly Volunteers.Status: Completed, Estimated PCD: 2020-01-01
Clinical trial
Intervention Specific Appendix to PLATFORMPBNAP1001: Evaluation of The Effect of Adalimumab on Inflammatory Mediators Following a Systemic Endotoxin ChallengeStatus: Completed, Estimated PCD: 2023-08-01
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LY3556050Product
AntraProduct
PrasugrelProduct
KJ103Clinical trial
A Randomized, Double-blind, Placebo- and Positive-controlled, Single-dose, 4-way Crossover Study to Evaluate the Effects of Aticaprant (JNJ-67953964) on Electrocardiogram Intervals in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2022-10-04
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DWP213388Clinical trial
A Phase I Study for Formulation Selection and Subsequent Optimization of Two Different Oral Formulations of Nintedanib in Healthy Male Subjects (Open-label, Randomised, Single-dose Study in Three Parts)Status: Completed, Estimated PCD: 2022-11-30
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Ofev®Product
LY3493269Clinical trial
A Single-blind, Randomised, Placebo-controlled, Parallel Group Design Phase I Trial to Investigate the Safety, Tolerability and Pharmacokinetics of Different Doses (Part A) and Different Treatment Regimens (Part B) of BI 765845 Administered to Healthy Male Subjects and Female Subjects of Non-childbearing PotentialStatus: Completed, Estimated PCD: 2023-06-07
Product
TramadolProduct
ParacetamolProduct
MepivacaineClinical trial
An Open-Label Study to Investigate the Effect of Selpercatinib on the Pharmacokinetics of Dabigatran in Healthy VolunteersStatus: Completed, Estimated PCD: 2021-05-17
Drug
RivaroxabanClinical trial
Modifying Genes in Cystic Fibrosis: The Beta-2 Adrenergic Receptors and Epithelial Na+ ChannelsStatus: Completed, Estimated PCD: 2012-07-01
Clinical trial
Long-term Effectiveness of the Antiobesity Medication PhentermineStatus: Recruiting, Estimated PCD: 2026-12-31
Product
Phentermine HydrochlorideProduct
I.M. PlaceboClinical trial
Vanderbilt University Medical CenterStatus: Active (not recruiting), Estimated PCD: 2025-11-30
Product
Sodium NitroprussideProduct
Hyperpolarized Xe129Product
PG-102(MG12)Clinical trial
A Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein SOSIP v8.2 763 Vaccine, Adjuvanted With MPLA Liposomes, in Healthy, HIV-Uninfected AdultsStatus: Recruiting, Estimated PCD: 2025-06-01
Clinical trial
A Randomized, Open-Label Study to Evaluate Potential Pharmacokinetic Interactions of Orally Administered Artemether-lumefantrine and Amodiaquine in Healthy Adult SubjectsStatus: Recruiting, Estimated PCD: 2026-08-31
Clinical trial
Direct Measurement of Gastrointestinal Permeability Change in Response to Aquamin®Status: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
The Modulatory Effects of Oxytocin on Reinforcement Learning and Interoceptive ProcessingStatus: Completed, Estimated PCD: 2021-09-20
Product
Zofran ODTClinical trial
Single-Dose Fasting Bioequivalence Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets (40 mg/25 mg; Mylan) to Benicar HCT® Tablets (40 mg/25 mg; Sankyo) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-11-01
Clinical trial
Impact of Formulation on the Pharmacokinetics of Micropatch-assisted Delivery of MetronidazoleStatus: Recruiting, Estimated PCD: 2024-09-01
Product
MetronidazoleClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Clopidogrel Bisulfate Tablets (75 mg; Mylan) to Plavix® Tablets (75 mg; Bristol-Myers Squibb/Sanofi) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-01-01
Clinical trial
Naturally Produced Cannabinoids for Pain Management and Neuroprotection From Concussion During Participation in Contact Sports: Dose EscalationStatus: Not yet recruiting, Estimated PCD: 2025-12-01
Clinical trial
A Phase 1, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Renal Function and Participants With Renal ImpairmentStatus: Completed, Estimated PCD: 2024-04-11
Clinical trial
Effects of Bacillus Calmette-Guérin (BCG) Immunization on Cerebrospinal Fluid (CSF) and Blood-Based Biomarkers in Older Adults: A PilotStatus: Completed, Estimated PCD: 2022-04-27
Clinical trial
Acute Dose-dependent Effects of DMT-bolus Applications in Healthy Subjects: A Placebo-controlled Cross-over Study (DMT BDR-Study).Status: Not yet recruiting, Estimated PCD: 2024-12-30
Clinical trial
An Intervention Study to Explore Potential Metabolic Effects of Ruminococcus Torques Strain ATCC 27756 in Healthy AdultsStatus: Completed, Estimated PCD: 2023-09-06
Product
Ruminococcus torquesClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Doxycycline Monohydrate Tablets (100 mg; Mylan) and Adoxa Tablets (100 mg; Par) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-07-01
Product
FlavanolClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Benazepril HCl and Hydrochlorothiazide Tablets (20 mg/25 mg; Mylan) to Lotensin HCT® Tablets (20 mg/25 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Product
Lotensin HCTProduct
HS-10398Product
Lidocaine topical systemProduct
OzoneClinical trial
PET Imaging of Synaptic Density Combined With Neuroimmunologic Measures to Reveal Mechanisms of HIV Neuropathogenesis During ARTStatus: Recruiting, Estimated PCD: 2027-12-01
Product
Carfentanil C-11Product
Rabeprazole SodiumClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Quinapril Hydrochloride Tablets (40 mg; Mylan) and Accupril® Tablets (40 mg; Parke-Davis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Clinical trial
Pharmacology of Mupirocin in Nasal Application in Healthy Volunteers: Monocentric StudyStatus: Recruiting, Estimated PCD: 2024-11-01
Product
MupirocinProduct
Blinded drug dose conditionsClinical trial
The Effect of Semaglutide on Pituitary FunctionStatus: Completed, Estimated PCD: 2021-09-23
Clinical trial
Bioequivalence of the BI 1015550 Low Dose Formulation C2 and the BI 1015550 Low Dose Formulation C1 (Phase 3 Formulation) Following Oral Administration in Healthy Subjects (an Open-label, Randomised, Single-dose, Two-way Crossover Trial)Status: Not yet recruiting, Estimated PCD: 2024-08-12
Product
FoodRxProduct
Glucophage XR 500 mgClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Alprazolam Extended-release Tablets (3 mg; Mylan) to Xanax XR® Tablets (3 mg; Pharmacia & Upjohn) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-08-01
Clinical trial
Single-Dose Food In Relative Bioavailability Study of Mylan Nitrofurantoin Macrocrystals 100 mg Capsules and Procter & Gamble Macrodantin® 100 mg Capsules in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-09-01
Drug
cannabidiolClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Pioglitazone HCl Tablets (45 mg; Mylan) and Actos® Tablets (45 mg; Takeda) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-03-01
Clinical trial
A Phase I Study to Evaluate the Effect of External Heat on the Pharmacokinetics of a Transdermal Granisetron Patch in Healthy SubjectsStatus: Completed, Estimated PCD: 2010-04-01
Product
GranisetronProduct
Metoprolol TartrateProduct
SYNB8802Clinical trial
A Bioequivalence Study of Injections of Mirikizumab Solution Using an Investigational 1-mL Pre-Filled Syringe and an Investigational 1-mL Autoinjector in Healthy ParticipantsStatus: Completed, Estimated PCD: 2021-05-17
Clinical trial
A Phase 1, Randomised, Oral Dose Trial to Evaluate the Effect of Food on LEO 152020 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2020-12-12
Clinical trial
An Open-Label Phase 1 Study in Healthy Adult Male Subjects to Investigate the Absorption, Metabolism, and Excretion of [14C]-HU6 Following Single-Dose Oral AdministrationStatus: Recruiting, Estimated PCD: 2024-05-22
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE BLIND, SPONSOR OPEN, PLACEBO-CONTROLLED STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF MULTIPLE ORAL DOSES OF PF-07054894 IN HEALTHY ADULT JAPANESE PARTICIPANTSStatus: Not yet recruiting, Estimated PCD: 2024-07-02
Product
HSK7653(5mg)Product
PUR3100Product
Tafamidis meglumineClinical trial
A Phase I Bridging Study to Evaluate the PK, PD, Safety and Tolerability of SR1375 in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-10-05
Clinical trial
A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Single-Dose Intravenous Study to Evaluate the Safety and Pharmacokinetics of IXT-m200 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-03-18
Product
Selected RegimenProduct
DihydroergotamineClinical trial
A Randomised, Double-Blind, Placebo-Controlled Phase I Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of MT-6345 in Healthy SubjectsStatus: Terminated, Estimated PCD: 2019-07-01
Clinical trial
A Clinical Trial to Compare and Evaluate the Safety and Bioequivalence of After Concomitant Administration of "SIPS-2209-2" and "SIPS-2209-3" and Single Administration of "SIPS-2209-1" in Healthy Adult Volunteers in Fasting Conditions.Status: Completed, Estimated PCD: 2022-09-01
Product
RLD2007Product
T6Product
AriceptProduct
DA-5207Clinical trial
A Phase I/II, Double-blind, Randomized, Active-controlled, Age De-escalation Trial to Assess Safety and Immunogenicity of a Measles Rubella Vaccine (MRV) Microneedle Patch (MRV-MNP) in Adults, MRV-primed Toddlers, and MRV-naïve InfantsStatus: Completed, Estimated PCD: 2022-11-23
Product
EU-ProliaClinical trial
A Two-Part Phase 1/2 Study to Determine Safety, Tolerability, Pharmacokinetics, and Activity of K0706, a Novel Tyrosine Kinase Inhibitor (TKI), in Healthy Subjects and in Subjects With Chronic Myeloid Leukemia (CML) or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL)Status: Active (not recruiting), Estimated PCD: 2026-08-01
Product
BMB-101Product
[14C]-TNP-2092Product
HSK7653(25mg)Clinical trial
AN INTERVENTIONAL, PHASE 1, OPEN-LABEL, FIXED-SEQUENCE, 2-PERIOD STUDY TO EVALUATE THE EFFECT OF A SINGLE ORAL DOSE OF ARV-471 (PF-07850327) ON THE PHARMACOKINETICS OF ROSUVASTATIN IN HEALTHY PARTICIPANTSStatus: Completed, Estimated PCD: 2023-03-06
Clinical trial
An Open-label, Single-dose, Parallel-group Study to Evaluate the Effects of Renal Function on Pharmacokinetics and Safety of DA-8010Status: Recruiting, Estimated PCD: 2024-03-01
Clinical trial
Disposition of [14C]-LY3437943 Following Subcutaneous Administration in Healthy Male ParticipantsStatus: Completed, Estimated PCD: 2023-06-23
Clinical trial
A Randomised, Single-blind, Placebo-controlled Trial to Investigate Safety, Tolerability, and Pharmacokinetics of Single Rising Doses of BI 1815368 Administered as Oral Solution to Healthy Male Subjects (SRD Part), and a Randomised, Open-label, Single-dose, Three-way Cross-over Part Investigating Relative Bioavailability of BI 1815368 as Tablet Versus Oral Solution and Tablet With and Without Food in Healthy Male Subjects (BA Part)Status: Completed, Estimated PCD: 2022-10-18
Product
SI-F019Clinical trial
A Sequential, Open-Label, Single-Dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of JNJ-80202135 Following a Single Intravenous Administration in Healthy Chinese Adult ParticipantsStatus: Completed, Estimated PCD: 2022-09-09
Product
B2Clinical trial
A Phase 2 Randomized, Open-Label, Parallel Group Study to Assess the Immunogenicity, Safety, and Tolerability of Moderna mRNA-1273 Vaccine Administered With Casirivimab+Imdevimab in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2022-11-21
Clinical trial
A Phase I, Single-Centre Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses of LY3526318, and to Investigate the Effect of LY3526318 on Metformin and Simvastatin Pharmacokinetics in Healthy Male Japanese ParticipantsStatus: Withdrawn, Estimated PCD: 2022-12-08
Clinical trial
A Phase I, Open-label, Fixed-sequence, Drug Interaction Study to Investigate the Effect of Multiple Oral Doses of Pirtobrutinib (LOXO-305) on the Pharmacokinetics of Repaglinide (CYP2C8 Substrate) in Healthy SubjectsStatus: Completed, Estimated PCD: 2020-12-30
Product
DWJ1248Product
PF-07261271Clinical trial
A Randomized, Open-label, Multiple-dose, Crossover Phase I Clinical Trial to Compare the Safety, Pharmacokinetics and Pharmacodynamics of JW0301 to C2105 in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-08-26
Clinical trial
A Randomised, Single-blind, Placebo-controlled Trial to Investigate Safety, Tolerability, and Pharmacokinetics of Single Rising Doses of BI 3031185 Administered as Tablet to Healthy Male Subjects, and a Randomised, Open-label, Single-dose, Two-way Cross-over Relative Bioavailability Comparison of BI 3031185 as Tablet With and Without Food in Healthy Male SubjectsStatus: Recruiting, Estimated PCD: 2024-07-09
Clinical trial
Relative Bioavailability of LY3074828 Solution Formulation in Pre-Filled Syringes Compared to Lyophilized Formulation After Single Subcutaneous AdministrationStatus: Completed, Estimated PCD: 2017-11-27
Clinical trial
A Randomised, Open-label, Single-dose, Two-way Cross-over Relative Bioavailability Comparison of BI 1595043 as Tablets With and Without Food in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2021-08-07
Product
RLD2302Clinical trial
A Phase 1, 2-part, Open-label, Fixed-sequence Study Evaluating the Effect of Rifampin (Part 1) and Rabeprazole (Part 2) on the Pharmacokinetics of a Single Dose of Camlipixant (BLU-5937) 50 mg Tablet in Healthy Participants Under Fasting ConditionsStatus: Completed, Estimated PCD: 2023-08-08
Clinical trial
Disposition of [14C]-LY3556050 Following Oral Administration in Healthy Male ParticipantsStatus: Completed, Estimated PCD: 2023-11-04
Clinical trial
Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BI 1584862 in Japanese Healthy Male Subjects (Single- Masked, Randomised, Placebo-controlled, Parallel Group Design)Status: Recruiting, Estimated PCD: 2024-05-28
Product
BI 1839100Product
MirikizumabProduct
BGB-DXP604Clinical trial
A Randomised Double-Blinded, Placebo-Controlled, Single and Multiple Ascending Dose, Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3876602 in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2025-06-01
Clinical trial
A Sequential, Randomized, Double-Blind, Placebo-Controlled, Phase 1 Single and Multiple Ascending Dose Study of LTG-001 Administered Orally to Evaluate the Safety, Tolerability, and Pharmacokinetics in Healthy Male and Female Participants 18 to 55 Years of AgeStatus: Recruiting, Estimated PCD: 2024-05-31
Product
NintedanibClinical trial
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3841136 in Healthy and Overweight ParticipantsStatus: Completed, Estimated PCD: 2024-01-25
Clinical trial
Pharmacokinetics of Imlunestrant in Participants With Hepatic ImpairmentStatus: Completed, Estimated PCD: 2024-02-28
Clinical trial
A Phase 1, Open-label, Fixed-sequence Study to Investigate the Effect of the Moderate CYP3A Inducer Rifabutin on the Pharmacokinetics of Zanubrutinib in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2020-11-10
Clinical trial
A Phase 1, Multi-cohort, Open-label Study to Evaluate the Relative Bioavailability of Capsule and Tablet Formulations of TYRA-300-B01, and to Evaluate the Safety, Tolerability, and Food Effect of TYRA-300-B01 Tablets in Healthy Adult ParticipantsStatus: Recruiting, Estimated PCD: 2024-05-01
Product
Iron supplementClinical trial
A Phase 1, Single-Center, Randomized, Open-Label, Bioavailability and Safety Three Period Crossover Multiple-Dose Study Comparing Two Dose Levels of AMZ001 (Diclofenac Sodium Gel 3.06%) and One Dose Level of Diclofenac Sodium 1% Gel in Healthy SubjectsStatus: Active (not recruiting), Estimated PCD: 2023-12-27
Clinical trial
A Phase I, Open-Label, Randomized, 2-Way Crossover Study to Compare the PK of Pirtobrutinib (LOXO-305) TabletsStatus: Completed, Estimated PCD: 2021-12-22
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, VEHICLE-CONTROLLED, PARALLEL COHORT STUDY TO EVALUATE THE SAFETY, TOLERABILITY, SKIN IRRITATION POTENTIAL AND PHARMACOKINETICS OF MULTIPLE-DOSE, TOPICAL ADMINISTRATION OF PF-07038124 TO JAPANESE HEALTHY PARTICIPANTSStatus: Completed, Estimated PCD: 2021-09-09
Clinical trial
Single-blind, Partially Randomised, Placebo-controlled Phase I Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Intravenous Doses of BI 655130 in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2016-05-27
Product
Microgynon®Product
PRA052Product
BGF MDI HFOProduct
Reference DrugClinical trial
A Phase 1, Randomized, 2-period, 2-sequence, Crossover With Parallel-group Extension, Open-label Study to Compare the Relative Bioavailability of 2 Oral Formulations of ALXN1840 in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2021-03-24
Clinical trial
A PHASE 1, OPEN-LABEL, SINGLE-PERIOD, NON-RANDOMIZED STUDY TO EVALUATE THE PHARMACOKINETICS, EXCRETION, MASS BALANCE AND METABOLISM OF [14C]PF-07265803 ADMINISTERED ORALLY TO HEALTHY ADULT MALE PARTICIPANTSStatus: Completed, Estimated PCD: 2022-05-26
Clinical trial
A Randomized, Double-blind, Placebo-controlled Phase 2a Study to Evaluate a Range of Dose Levels of an Ad26.RSV.preF-based Vaccine in Adults Aged 60 Years and OlderStatus: Completed, Estimated PCD: 2020-09-24
Clinical trial
A Randomized, Double-blind, Placebo-controlled, Single-ascending Dose Phase Ⅰa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of STSA-1002Following Intravenous Infusion in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-01-12
Clinical trial
A Randomized Phase I, Open-Label, Active-Controlled Study Assessing The BE Between Single Doses of 500 mg GXR RM Tablets and 500 mg GXR Tablets Under Fasted and Fed State in Two 2-Way Crossover Groups of Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-03-11
Product
FamotidineProduct
Test DrugProduct
BentracimabClinical trial
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3372993 in Participants With Alzheimer's Disease and Healthy ParticipantsStatus: Active (not recruiting), Estimated PCD: 2024-08-30
Clinical trial
A Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of RTA 901 in Healthy AdultsStatus: Completed, Estimated PCD: 2017-07-23
Product
BLU-5937Product
LY3437943Clinical trial
A Randomized, Double-blind, Placebo-controlled Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses and Multiple Dose of HSK31679 in Healthy Volunteers and Subjects With Elevated LDL-CStatus: Completed, Estimated PCD: 2022-09-21
Product
ENC1018Clinical trial
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Oral Doses of BI 894416 in Healthy Male Subjects (Single-blind, Partially Randomised, Placebo-controlled Parallel Group Design)Status: Completed, Estimated PCD: 2018-09-10
Clinical trial
A Randomized Clinical Trial to Investigate Two-Week Clinical Safety, Changes in Salivary Flow and pH Following Use of an Anticavity Low pH MouthwashStatus: Completed, Estimated PCD: 2023-08-03
Product
Camlipixant + GemfibrozilProduct
Insulin DegludecClinical trial
A Single- and Multiple-Ascending Dose Study in Healthy Subjects to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3298176 and Multiple Doses in Patients With Type 2 Diabetes MellitusStatus: Completed, Estimated PCD: 2017-06-26
Clinical trial
A PHASE 1, OPEN-LABEL, RANDOMIZED, THREE-TREATMENT, THREE-PERIOD, CROSSOVER, SINGLE DOSE STUDY TO ESTIMATE THE RELATIVE BIOAVAILABILITY OF 61 MG AND 70 MG TAFAMIDIS FREE ACID TABLETS TO COMMERCIAL 61 MG TAFAMIDIS FREE ACID CAPSULE ADMINISTERED UNDER FASTED CONDITIONS IN HEALTHY ADULT PARTICIPANTSStatus: Active (not recruiting), Estimated PCD: 2024-05-27
Clinical trial
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RTA 408 Lotion in Healthy VolunteersStatus: Completed, Estimated PCD: 2014-04-01
Product
LY3410738Clinical trial
The Effect of Multiple Doses of Carbamazepine on the Pharmacokinetics of a Single Oral Dose of BI 1810631 in Healthy Male Subjects (an Open-label, Two-period, Fixed-sequence Trial)Status: Completed, Estimated PCD: 2023-12-08
Product
Dabigatran etexilateProduct
Proair HFAClinical trial
A Phase I, Open Label, Fixed-sequence Drug Interaction Study to Investigate the Effect of Multiple Oral Doses of LOXO-305 on the Pharmacokinetics of a Single Dose of Intravenous and Oral Midazolam (CYP3A4 Substrate) in Healthy SubjectsStatus: Completed, Estimated PCD: 2020-10-20
Clinical trial
An Open-Label, 2-Part Study to Investigate the Effect of Lasmiditan on the Pharmacokinetics of Dabigatran and Rosuvastatin in Healthy VolunteersStatus: Completed, Estimated PCD: 2021-07-06
Product
RosuvastatinClinical trial
An Open-Label, Two-Period, Randomized, Single Oral Dose, Crossover Study to Evaluate the Bioequivalence of Tasimelteon Capsule Formulation Relative to Tasimelteon Liquid Suspension Formulation in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-06-15
Clinical trial
An Open-label, Fixed-sequence, Phase 1 Clinical Trial to Evaluate the Effect of Clarithromycin/Rifampicin on the Pharmacokinetics of DA-8010 in Healthy AdultsStatus: Completed, Estimated PCD: 2023-11-06
Product
ClarithromycinClinical trial
A Phase I, Participant- and Investigator-Blind, Single-center Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of LY3871801 in Healthy Asian and Non-Asian ParticipantsStatus: Completed, Estimated PCD: 2023-10-25
Product
RifampicinProduct
LY3844583Clinical trial
A Phase 1, Open-label, Study of the Absorption, Metabolism, and Excretion of [14C]-KBP-5074 Following a Single Oral Dose in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2020-12-23
Product
CS32582Clinical trial
Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses and Multiple Oral Doses of BI 1323495 Versus Placebo in Healthy Male Japanese Subjects Genotyped as Poor and Extensive Metabolizers of UGT2B17 (Single-blind, Randomised, Placebo-controlled [Within Dose Groups] Trial), Including an Investigation of Drug-drug Interaction With Itraconazole in Healthy Male Subjects Genotyped as Poor Metabolizers of UGT2B17 (an Open-label, Two-period, Fixed Sequence Trial)Status: Completed, Estimated PCD: 2021-07-30
Product
rHuPH20Product
DigoxinProduct
MoxifloxacinProduct
PF-07265803Product
CEL383Product
NalmefeneProduct
RTA 408Clinical trial
Safety, Tolerability, and Pharmacokinetics of Single Rising Intravenous Doses of BI 765845 in Healthy Male Japanese Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2023-12-17
Product
M5717Product
Fentanyl Transdermal SystemClinical trial
Palatability Study of a Novel Paediatric Formulation of Tachipirina® With Strawberry FlavourStatus: Completed, Estimated PCD: 2022-04-25
Product
Oxybutynin ChlorideClinical trial
A Randomized, Single-dose, Open-label, Two-way Crossover Pivotal Study to Assess the Bioequivalence Between Albuterol Sulfate Inhalation Aerosol 108 mcg Per Actuation (MDI, eq. to Albuterol 90mcg/Puff) and Proair HFA (Albuterol Sulfate) Inhalation Aerosol 90 mcg Per Actuation (MDI, eq. to Albuterol 90mcg/Puff) in Healthy Volunteers Under Fasting ConditionsStatus: Completed, Estimated PCD: 2021-05-10
Clinical trial
A Single-dose, Open-label, Randomized, Two-treatment, Two-period, Crossover Study in Healthy Subjects to Assess the Bioequivalence of the Newly Formulated Tylenol® Tablet (Acetaminophen) to the Tylenol® 8H ER Tablet (Acetaminophen) Under Fasting ConditionsStatus: Completed, Estimated PCD: 2020-02-10
Product
Bowel prepClinical trial
Phase I, Open-label, Single-sequence, Cross-over Study of the Effect of Multiple Doses of Itraconazole on Single-dose Tepotinib Pharmacokinetics in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-07-05
Product
TirzepatideClinical trial
A Drug-Drug Interaction Study to Assess the Effect of Orforglipron on the Pharmacokinetics of Digoxin, Simvastatin, Rosuvastatin, Acetaminophen, and Midazolam in Healthy Overweight and Obese ParticipantsStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
Effect of Injection Site on the Relative Bioavailability of a Single Dose of LY3437943 in Healthy Participants With a High Body Mass IndexStatus: Active (not recruiting), Estimated PCD: 2024-07-01
Clinical trial
A PHASE 1, OPEN-LABEL, 2-PERIOD STUDY TO EVALUATE THE EFFECT OF MULTIPLE DOSES OF ESOMEPRAZOLE ON THE PHARMACOKINETICS OF SINGLE DOSE VEPDEGESTRANT (ARV-471, PF-07850327) UNDER THE FED CONDITION IN HEALTHY ADULT MALES AND HEALTHY ADULT FEMALES OF NONCHILDBEARING POTENTIALStatus: Recruiting, Estimated PCD: 2024-05-03
Product
AvenciguatProduct
Letrozole LEBEProduct
C1KProduct
XH-S003Product
PRA023 IVClinical trial
Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Dose and Multiple Rising Oral Doses of BI 706321 in Healthy Japanese Male Subjects and Single Oral Dose of BI 706321 in Healthy Chinese Male Subjects (Double-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Recruiting, Estimated PCD: 2025-10-21
Product
OrforglipronProduct
Flupentixol + MelitracenProduct
BI 425809Product
VupanorsenClinical trial
Safety, Tolerability and Pharmacokinetics of Multiple Rising Oral Doses of BI 1595043 (Double-blind, Randomised, Placebocontrolled, Parallel Group Design) in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-01-14
Product
PF-07104091Product
TepotinibProduct
WarfarinProduct
AtorvastatinClinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Rising Intravenous Infusion or Subcutaneous Injection Doses of BI 765250 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Active (not recruiting), Estimated PCD: 2024-09-16
Product
Yasmin®Clinical trial
An Open-label, Fixed-sequence Cross-over, Two-period, Phase I Trial to Evaluate the Effect of Multiple Doses of BI 1358894 on the Pharmacokinetics of a Combination of Ethinylestradiol and Drospirenone in Healthy Female SubjectsStatus: Terminated, Estimated PCD: 2024-02-08
Product
CS12192Clinical trial
A PHASE 1, OPEN-LABEL, RANDOMIZED, SINGLE DOSE, CROSSOVER STUDY TO ESTIMATE THE RELATIVE BIOAVAILABILITY OF PF-07817883 FOLLOWING ORAL ADMINISTRATION OF NEW FORMULATIONS RELATIVE TO THE REFERENCE FORMULATION IN HEALTHY ADULT PARTICIPANTS UNDER FASTED CONDITIONStatus: Completed, Estimated PCD: 2024-01-12
Product
ALXN1840Product
FP-020Clinical trial
Interventional, Randomized, Single Dose, Open-label, Crossover, Bioequivalence Study in Healthy Men and Women to Compare Two Pharmaceutical Formulations of Flupentixol/Melitracen (Deanxit®) - in Fasted and Fed ConditionsStatus: Completed, Estimated PCD: 2018-06-28
Product
ND-003Clinical trial
Development of Applications of PillCam™ Endoscopy and Patency Systems and Clinical Evaluation of Their Performance in Healthy Volunteers ("HEIGHT" Study)Status: Terminated, Estimated PCD: 2023-03-27
Product
VepdegestrantProduct
LC542019Clinical trial
A Phase 1, Open Label, Nonrandomized, Single-dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of KBP-5074 in Subjects With Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic FunctionStatus: Completed, Estimated PCD: 2020-11-19
Clinical trial
Relative Bioavailability of 40 mg/0.4 mL of BI 695501 Compared to 40 mg/0.8 mL of BI 695501 Formulation Following Single Subcutaneous Administration in Healthy Male and Female Subjects (a Double Blind, Randomised, Single-dose, Parallel-arm Study)Status: Completed, Estimated PCD: 2022-08-29
Product
Chlorhexidine gluconateClinical trial
A Phase 1, Single-centre, Dose-escalation Study Utilising Both Open-label and Double-blind Placebo-controlled Crossover Design Studies to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Low Doses of Lysergic Acid Diethylamide Ranging From 50 µg to 100 µg in Healthy VolunteersStatus: Completed, Estimated PCD: 2016-07-26
Product
PaxalisibProduct
EtanerceptProduct
RLD2202Clinical trial
Interventional, Randomized, Double-blind, Placebo-controlled, Single-ascending-dose Study Investigating the Safety, Tolerability, and Pharmacokinetic Properties of Lu AF87908 in Healthy Subjects and Patients With Alzheimer's DiseaseStatus: Completed, Estimated PCD: 2023-07-19
Clinical trial
Effect of Tirzepatide on Oral Contraceptive Pharmacokinetics in Healthy Female SubjectsStatus: Completed, Estimated PCD: 2021-02-09
Product
NipocalimabProduct
JYB1904Clinical trial
A Randomised, Single-blind, Placebo-controlled Trial to Investigate Safety, Tolerability, and Pharmacokinetics of Single Rising Doses of BI 1584862 Administered as Tablet to Healthy Male Subjects (SRD Part), and a Randomised, Open-label, Single-dose, Two-way Crossover Part Investigating Relative Bioavailability of BI 1584862 as Tablet With and Without Food in Healthy Male Subjects (FE Part)Status: Completed, Estimated PCD: 2023-03-06
Product
EDP1815Product
Standard of coreProduct
SelpercatinibClinical trial
A Single-Dose, Randomized, Double-Blind, Placebo- and Positive-Controlled, 4-Way Crossover Study to Evaluate the Effect of LOXO-292 on the QTc Interval in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2019-06-21
Product
IXT-m200Clinical trial
Evaluation of the Effect of LY3871801 on the Pharmacokinetics of CYP450 Substrates and an OAT1/3 Substrate in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-03-29
Product
AbilifyProduct
BPDO-1603Product
ARV-471Product
SafinamideProduct
BIIB014Clinical trial
A Randomized, Double-Blind, Placebo-Controlled, Crossover Study to Assess the Effect of BIIB014 on the Pharmacokinetics of Rosiglitazone, Warfarin, and Midazolam in Healthy VolunteersStatus: Completed, Estimated PCD: 2010-06-02
Clinical trial
Randomized, Double-blind, Placebo-controlled, Dose Escalation Study for the Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Ascending Oral Doses of IOA-289 in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2021-09-07
Clinical trial
Relative Bioavailability of BI 1810631 as Two Different Oral Formulations Given as Single Doses and Investigation of the Effects of Food and Multiple-dose Rabeprazole on the Pharmacokinetics of Single-dose BI 1810631 Following Oral Administration in Healthy Male Subjects (an Open-label, Randomised, Four-way Crossover Trial)Status: Completed, Estimated PCD: 2022-09-13
Clinical trial
Phase I, Open-label, Three-Period Crossover Study to Investigate the Effect of a Proton Pump Inhibitor (Omeprazole) on the PK of Tepotinib in Healthy SubjectsStatus: Completed, Estimated PCD: 2018-07-02
Product
OmeprazoleClinical trial
A Single-Dose, Partial-Replicate, Pharmacokinetic, and Comparative Bioavailability Study of Rupatadine 10 mg Tablets and Clarinex® 5 mg Tablets Under Fasting ConditionsStatus: Completed, Estimated PCD: 2022-01-13
Clinical trial
A Phase I, Randomized, Open-Label, Single-Dose, Crossover Study to Evaluate Food Effect on the Pharmacokinetics and Safety of CT-L01 After Oral Administration in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-07-19
Clinical trial
A Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study to Investigate Safety, Tolerability, and Pharmacokinetics of JNJ-77242113 in Healthy Japanese Participants and a Single Dose Study to Investigate Safety, Tolerability, and Pharmacokinetics of JNJ-77242113 in Healthy Chinese ParticipantsStatus: Completed, Estimated PCD: 2022-09-28
Clinical trial
A Study of the Safety, Tolerability, Microbial Kinetics and Effect on Urinary Oxalate Excretion of FB-001 in Healthy Volunteers Fed a High Oxalate/Low Calcium Diet and in Patients With Enteric HyperoxaluriaStatus: Recruiting, Estimated PCD: 2024-08-31
Product
MRV-MNPClinical trial
A Single-center, Open-label, Single-dose, Randomized, 3-way Crossover Phase 1 Study in Healthy Adult Participants to Assess the Relative Oral Bioavailability of Macitentan 75 mg as Two Different Test Formulations Compared to the Reference FormulationStatus: Completed, Estimated PCD: 2022-08-30
Clinical trial
A Phase 1 Clinical Trial to Evaluate the Effect of Food on the Pharmacokinetics and Safety of DWP16001 After Administration in Healthy Adult VolunteersStatus: Recruiting, Estimated PCD: 2023-05-31
Clinical trial
A Phase 1 Double-Blind, Placebo-Controlled, Single- and Multiple-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Nipocalimab in Healthy Male and Female ParticipantsStatus: Completed, Estimated PCD: 2022-05-26
Clinical trial
Relative Bioavailability of a Single Oral Dose of Digoxin, Furosemide, Metformin, and Rosuvastatin Given Alone and All Together as a Cocktail, and Investigation of the Effect of Increased Doses of Metformin or Furosemide on Relative Bioavailability of the Other Cocktail Compounds in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2015-01-01
Product
ApipeProduct
EE/NGMProduct
bosentanClinical trial
A Phase 1, Open-Label, Multiple-Dose, Parallel Study to Determine the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of ALXN2050 in Adult ParticipantsStatus: Recruiting, Estimated PCD: 2024-04-05
Product
RTVClinical trial
Relative Bioavailability of a Single Oral Dose of BI 730357 When Administered Alone or in Combination With Multiple Oral Doses of Itraconazole in Healthy Male Subjects (an Open-label, One-way Crossover Study)Status: Completed, Estimated PCD: 2019-03-11
Clinical trial
A PHASE I, SINGLE CENTER, OPEN-LABEL STUDY TO ASSESS THE PHARMACOKINETICS, SAFETY AND TOLERABILITY OF AZTREONAM-AVIBACTAM ADMINISTERED AS SINGLE AND REPEATED INTRAVENOUS DOSES IN HEALTHY CHINESE PARTICIPANTSStatus: Completed, Estimated PCD: 2021-09-27
Clinical trial
A Phase 1 Study to Evaluate the Effect of Food on the Pharmacokinetics of LOXO-783 in Healthy Adult SubjectsStatus: Recruiting, Estimated PCD: 2023-12-01
Product
IruplinalkibClinical trial
An Open-label, Fixed-sequence Study to Evaluate the Drug-drug Interactions Between Tegoprazan Tablets and Bismuth Potassium Citrate Capsules, Amoxicillin Capsules, and Clarithromycin Tablets in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-04-28
Product
RepaglinideProduct
QuinidineProduct
[phenyl-14C]ARV-471Product
KetoconazoleProduct
Tafamidis free acidProduct
ClopidogrelProduct
RitlecitinibProduct
EvobrutinibClinical trial
The Effect of BI 730357 on the Pharmacokinetics of Rosuvastatin, Digoxin, Metformin and Furosemide Given as a Cocktail - an Open-label, Non-randomised, 2-period Fixed-sequence Trial in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-01-11
Product
BPI-16350Product
JNJ-77474462Clinical trial
A Single-center, Open-label Study Evaluating the Pharmacokinetics, and Safety of Multiple Dose Oral Brexpiprazole Tablets (1 mg) in Chinese Healthy SubjectsStatus: Completed, Estimated PCD: 2020-06-10
Product
Lu AG06474Product
LY3509754Clinical trial
A Phase 1, Randomized, Participant-and Investigator-Blind, Placebo-Controlled, Single-and Multiple-Ascending Dose, Drug-Drug Interaction and Food Effect Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3509754 in Healthy Non-Japanese and Japanese ParticipantsStatus: Terminated, Estimated PCD: 2022-10-14
Clinical trial
Investigation of Pharmacokinetics and Absolute Oral Bioavailability of BI 730357 Administered as an Oral Dose With an Intravenous Microtracer Dose of BI 730357 BS (C-14) in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2019-03-26
Product
DabigatranClinical trial
Phase I, Open-label, Single Sequence, Two-Period Study to Evaluate the Effect of Tepotinib on P-gp by Investigating the PK of the P-gp Probe Substrate Dabigatran Etexilate in Healthy SubjectsStatus: Completed, Estimated PCD: 2018-08-27
Clinical trial
Bioavailability, Pharmacokinetics and Safety Evaluation of Phencynonate Hydrochloride in Healthy VolunteersStatus: Completed, Estimated PCD: 2010-01-01
Clinical trial
A Phase I Dose Escalation Study of Ascending Single and Multiple Doses of the MEK Inhibitor Zapnometinib in Healthy Subjects to Evaluate the Safety & Tolerability Compared to Placebo, Additionally Evaluating Pharmacokinetics and Pharmacodynamics of Target Engagement, as Well as Investigating Possible FDI and DDIStatus: Completed, Estimated PCD: 2023-07-20
Product
DonanemabClinical trial
A Study to Investigate Continuous Blood Pressure Monitoring Using Traditional Device (ABPM) Versus Novel Devices (Biobeat and Aktiia)Status: Completed, Estimated PCD: 2023-04-04
Clinical trial
A Trial Investigating the Pharmacodynamics of BC Combo THDB0207 Compared With Humalog® Mix25 and Simultaneous Injections of Humalog® and Lantus® in Healthy Chinese VolunteersStatus: Completed, Estimated PCD: 2022-12-04
Product
OmalizumabProduct
BI 3000202Product
Placebo matching BI 3000202Product
[14C]-LOXO-305Product
TerbinafineProduct
LamisilClinical trial
Relative Bioavailability and the Effect of Food on the Bioavailability of LY3337641 in Healthy SubjectsStatus: Completed, Estimated PCD: 2017-05-31
Product
BI 685509Product
IohexolProduct
Percoffedrinol®Product
CSL324Product
ACT-246475Clinical trial
A Single-center, Open-label, Single-dose, Randomized, 2-way Crossover Phase 1 Study in Healthy Adult Participants to Assess the Bioequivalence of the Dispersible Final Market Image (FMI) Macitentan Tablet (4 x 2.5 mg) and the Opsumit Tablet (10 mg) in Fasted ConditionsStatus: Completed, Estimated PCD: 2022-08-31
Product
Tramadol HydrochlorideClinical trial
A Randomized, Single-blinded, Placebo Controlled, Single Ascending Dose Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of KJ103 in Healthy SubjectsStatus: Active (not recruiting), Estimated PCD: 2023-03-18
Product
Ad26.ZEBOV-Batch #1Clinical trial
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Immunogenicity, Safety and Tolerability of a Heterologous Prime-Boost Regimen Using Three Different Batches of Ad26.ZEBOV and a Single Batch of MVA-BN®-Filo in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2016-01-22
Product
AticaprantProduct
SKL24741Clinical trial
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Subcutaneous Doses of BI 655064 in Healthy Chinese Male Volunteers (Randomised, Double-blind, Placebo-controlled, Clinical Phase I Study)Status: Completed, Estimated PCD: 2016-05-25
Product
napabucasinProduct
MZE001Product
MGTA-145Product
Bowel prep combinationClinical trial
Effect of Opioids and NSAIDs on Sympathetic Nervous System and Vascular Function in Healthy Subjects and Patients With OsteoarthritisStatus: Recruiting, Estimated PCD: 2025-07-31
Clinical trial
Assessment of Neuroinflammation in Central Inflammatory Disorders Using [F-18]DPA-714.Status: Recruiting, Estimated PCD: 2025-04-10
Clinical trial
Understanding Rebound Pain After Regional Anesthesia Resolution: Mechanistic Trial in Healthy VolunteersStatus: Recruiting, Estimated PCD: 2024-12-01
Product
18F-SF12051Clinical trial
A Phase 1a, Dose-finding, Open-label Trial Followed by a Phase 1b, Double-blind, Randomised, Placebo-controlled Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of the Tuberculosis Subunit Vaccine H107e/CAF®10b in AdultsStatus: Recruiting, Estimated PCD: 2026-05-01
Product
H107e/CAF10bProduct
H107e/CAF®10bProduct
I.D. PlaceboProduct
PhentolamineProduct
Low Dose Regular insulinProduct
Regular insulinProduct
0.20% CHX and Cymenol gelClinical trial
Hyperpolarized 129Xe MRI to Identify Structural Determinants of Low Lung Function and Respiratory Symptoms in Young Adults From the Lung Health CohortStatus: Recruiting, Estimated PCD: 2027-03-31
Clinical trial
Safety, Tolerability and Pharmacokinetics of Single Oral Doses of BI 409306 (Tablet) in Healthy Chinese and Japanese Male Volunteers and Multiple Oral Doses of BI 409306 (Tablet) in Healthy Japanese Male Volunteers (Randomised, Double-blind, Placebo-controlled Within Dose Groups)Status: Completed, Estimated PCD: 2013-07-18
Product
BI 3034701Product
OndansetronProduct
PioglitazoneClinical trial
An Open-Label Pharmacokinetic Study to Evaluate the Bioavailability of Oral Primaquine and the Pharmacokinetics of Carboxyprimaquine in Healthy Adult SubjectsStatus: Withdrawn, Estimated PCD: 2025-03-01
Product
Regimen 1Clinical trial
Evaluation of Halitosis Using a Multi-Mineral Approach (Aquamin®)Status: Recruiting, Estimated PCD: 2025-07-01
Clinical trial
Mood Effects of Serotonin Agonists ExtendedStatus: Completed, Estimated PCD: 2021-06-07
Clinical trial
Return of Genomic Results and Aggregate Penetrance in Population-Based CohortsStatus: , Estimated PCD: 2024-06-30
Product
Clopidogrel BisulfateProduct
PlavixClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Doxycycline Monohydrate Tablets (100 mg; Mylan) and Adoxa Tablets (100 mg; Par) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-08-01
Product
AdoxaProduct
PsilocybinProduct
LY3873862Product
Glycine BufferClinical trial
Microbial, Immune, and Metabolic Perturbations by Antibiotics (MIME Study)Status: Recruiting, Estimated PCD: 2024-11-01
Clinical trial
Oxytocin Modulates the Processing of the Advantageous- and Disadvantageous-inequityStatus: Active (not recruiting), Estimated PCD: 2024-05-20
Product
ReboxetineProduct
NicotineClinical trial
Effects of Lysergic Acid Diethylamide (LSD) on Neuroplasticity in Healthy Human SubjectsStatus: Recruiting, Estimated PCD: 2024-12-01
Product
Benzoyl peroxideProduct
PsilocinClinical trial
Effect of Stimulant Drugs on Social PerceptionStatus: Completed, Estimated PCD: 2018-08-01
Product
methamphetamineClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Terbinafine Hydrochloride Tablets (250 mg; Mylan) to Lamisil® Tablets (250 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-03-01
Product
Lamisil TabletsClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets (100/50 mg; Mylan) to Lopressor HCT® Tablets (100/50 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-02-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Glipizide and Metformin HCl Tablets (5 mg/500 mg; Mylan) to Metaglip® Tablets (5 mg/500 mg; Bristol-Myers Squibb) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-06-01
Clinical trial
A PHASE 1, OPEN-LABEL, RANDOMIZED, SINGLE-DOSE, PARALLEL DESIGN, STUDY TO EVALUATE PHARMACOKINETIC COMPARABILITY OF TWO PF-07940367 FILM-COATED TABLET FORMULATIONS ADMINISTERED AS 150 MG UNDER FASTED CONDITIONS IN HEALTHY PARTICIPANTSStatus: Recruiting, Estimated PCD: 2024-08-19
Clinical trial
Single-Dose Fed Bioequivalence Study of Balsalazide Disodium Capsules (750 mg; Mylan) and Colazal® Capsules (750 mg; Salix) in Healthy VolunteersStatus: Completed, Estimated PCD: 2007-02-01
Product
ColazalProduct
OlanzapineClinical trial
Single Dose Crossover Comparative Bioavailability Study of Baclofen 20 mg Tablets in Healthy Male Volunteers / Fasting StateStatus: Completed, Estimated PCD: 2003-11-01
Drug
KetamineProduct
Ts-134Product
SV2A PETProduct
TSPO PETClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Midodrine HCl Tablets (5 mg; Mylan) and ProAmatine® Tablets (5 mg; Roberts) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-08-01
Product
ProAmatineClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Quinapril HCl and Hydrochlorothiazide Tablets (20 mg/25 mg; Mylan) to Accuretic™ Tablets (20 mg/25 mg; Parke-Davis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-08-01
Clinical trial
The Effects of Oral Vasopressin on Attention Control: An Eye-tracking StudyStatus: Recruiting, Estimated PCD: 2025-06-01
Clinical trial
Pilot Study of a Multi-System Analysis of Opioid Receptor BindingStatus: Recruiting, Estimated PCD: 2025-09-01
Clinical trial
A Multiple-Dose Study to Investigate the Bioequivalence of Orforglipron (LY3502970) Capsules and Orforglipron Tablets in Participants With Obesity or Overweight Who Are Otherwise Healthy.Status: Not yet recruiting, Estimated PCD: 2025-05-21
Clinical trial
A Bioequivalence Study of Subcutaneous Injections of LY3209590 in Two Formulations in Healthy ParticipantsStatus: Completed, Estimated PCD: 2024-01-18
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Rabeprazole Sodium Tablets (20 mg; Mylan) and Aciphex® Tablets (20 mg; Eisai) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-06-01
Clinical trial
Effects of Administration of Growth Hormone, Without and With Liraglutide, on AgRP, Energy and Glucose Metabolism in Healthy and GH Deficient HumansStatus: Recruiting, Estimated PCD: 2028-04-30
Product
Growth Hormone + LirglutideProduct
Growth HormoneClinical trial
Investigating the Effects of Nabilone on Endocannabinoid Metabolism in the Human BrainStatus: Recruiting, Estimated PCD: 2026-10-01
Product
NDV-HXP-SClinical trial
Targeting Cellular Senescence With Senolytics to Improve Skeletal Health in Older Humans: A Phase 2, Single-Center, 20-week, Open-Label, Randomized Controlled Trial.Status: Active (not recruiting), Estimated PCD: 2023-06-06
Product
DasatinibProduct
FisetinProduct
FluoxetineProduct
OcalivaClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Finasteride Tablets (5 mg; Mylan) and Proscar Tablets (5 mg; Merck) in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2004-10-01
Product
FexofenadineProduct
AllegraClinical trial
Effects of Dietary Conditions on Drug ResponseStatus: Terminated, Estimated PCD: 2023-02-02
Clinical trial
The Effects of Intrapartum Antibiotic Prophylaxis to Prevent Group B Streptococcal Early-onset Disease on Intestinal Microbiome and Immunity of OffspringStatus: , Estimated PCD: 2023-06-30
Clinical trial
Food Prescriptions to Promote Affordable Diets That Meet RDAs Among Multi-generational Latino HouseholdsStatus: Recruiting, Estimated PCD: 2026-01-15
Product
Metformin Hydrochloride ERClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Carvedilol Tablets (12.5 mg; Mylan) to Coreg® Tablets (12.5 mg; GSK) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-04-01
Product
CarvedilolProduct
Xanax XRProduct
MacrodantinClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Carvedilol Tablets (12.5 mg; Mylan) to Coreg® Tablets (12.5 mg; GSK) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-04-01
Product
TadalafilProduct
granisetronClinical trial
Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant DepressionStatus: Recruiting, Estimated PCD: 2025-12-31
Clinical trial
A Two-way Crossover, Open-label, Single-dose, Fasting, Bioequivalence Study of Meloxicam 15 mg Tablets Versus Mobic® 15 mg Tablets in Normal Healthy Non-Smoking Male and Female SubjectsStatus: Completed, Estimated PCD: 2004-02-01
Product
MeloxicamProduct
MobicClinical trial
A Pharmacokinetics Study of CM310 Recombinant Humanized Monoclonal Antibody Injection in Healthy SubjectsStatus: Not yet recruiting, Estimated PCD: 2025-04-30
Clinical trial
Single-blind, Randomised, Placebo-Controlled Trial on the Safety, Tolerability, and Pharmacokinetics of Single Rising Doses and Multiple Doses of Intravenous BI 3802876 in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-10-22
Product
[14C]-BI 1291583Product
BI 1820237Clinical trial
A Phase I, Single-arm, Open-label, Ethnobridging Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) of Single and Multiple Oral Doses of Hemay005 Tablets in Healthy Caucasian Adult VolunteersStatus: Completed, Estimated PCD: 2023-08-08
Product
LopressorProduct
LY3541860Product
Rosuvastatin + BI 1323495Clinical trial
Phase I, Randomised, Double-masked, Placebo-controlled, Combined Single and Multiple Ascending Dose Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Male and Female VolunteersStatus: Completed, Estimated PCD: 2013-02-01
Product
PB2452Clinical trial
A Phase 1, Randomized, Placebo-controlled, Investigator and Participant Blinded, Single Ascending Dose and Multiple Ascending Dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of LY3985297 in Healthy ParticipantsStatus: Not yet recruiting, Estimated PCD: 2025-07-01
Product
Polyene PhosphatidylcholineProduct
PF-07054894Clinical trial
Effects of Iclepertin on the QT Interval Following Oral Administration in Healthy Male and Female Subjects (a Double-blind, Randomised, Placebo-controlled, Multiple-dose, Parallel Group With Nested Crossover Design Trial, With Moxifloxacin as Positive Control)Status: Recruiting, Estimated PCD: 2024-05-28
Clinical trial
An Open-label Study Assessing the Ocular and Systemic Safety and Systemic Absorption of AR-13324 Ophthalmic Solution, 0.02% in Healthy VolunteersStatus: Completed, Estimated PCD: 2013-11-01
Product
KH607Clinical trial
Pharmacokinetics, Safety and Tolerability of BI 1015550 Following Oral Administration in Male and Female Participants With Different Degrees of Renal Impairment (Severe and Moderate) as Compared With Individually Matched Male and Female Participants With Normal Renal Function (an Open-label, Non-randomised, Single Dose, Parallel, Individual-matched Design Trial)Status: Completed, Estimated PCD: 2023-08-15
Product
Placebo comparatorClinical trial
To Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LPM3480392 Injection at Different Rates in Healthy Subjects in a Phase I Clinical TrialStatus: Completed, Estimated PCD: 2022-03-09
Product
Benazepril HClClinical trial
A Prospective, Open-label, Single-dose Phase 1 Study to Measure Daridorexant in Breast Milk of Healthy Lactating WomenStatus: Completed, Estimated PCD: 2023-04-30
Clinical trial
A Randomized, Single-center, Double-blind, Placebo Controlled Trial With Ascending Multiple Intravenous Doses to Determine Safety, Tolerability and Pharmacokinetics of AON-D21 in Healthy Male Subjects.Status: Completed, Estimated PCD: 2022-11-29
Product
HSK36273Clinical trial
A Phase 1, Single Center, Randomized, Controlled Platform Study Validating the Use of Candin as a Challenge Agent in Healthy Volunteers or Patients Given Concomitant Approved InterventionsStatus: Completed, Estimated PCD: 2021-09-21
Clinical trial
A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Dose Range Finding Study to Assess the Safety, Tolerability, PD and PK of RLS-0071 in Healthy Adult Subjects After Challenge With Inhaled Lipopolysaccharide (LPS)Status: Completed, Estimated PCD: 2022-09-21
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RLD2008Clinical trial
An Open Label, Randomized, Single Dose, Cross-over ,Two-group Study to Evaluate the Pharmacokinetics and Safety of DA-1229_01 5/1000mg in Healthy Subjects at Fasting StateStatus: Not yet recruiting, Estimated PCD: 2023-04-21
Product
T3Product
R2Product
T5Product
Compound-XClinical trial
A Randomized, Double-blind, Placebo-controlled, Dose-increasing Phase I Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Intravenous Infusion of LPM3480392 Injection in Healthy SubjectStatus: Completed, Estimated PCD: 2021-11-02
Product
DWP16001Product
AR-13324Clinical trial
An Adaptive Design, Phase 1, Open-label Study to Investigate Receptor Occupancy in Brain After Single Oral Doses of LY3857210 as Measured by Positron Emission Tomography (PET) With the Radioligand [18F]-LY3818850 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-12-14
Clinical trial
A Phase 1, Open-Label, Multi-Dose Study to Assess the Systemic and Local Tissue Pharmacokinetics and Pharmacodynamics of JNJ-64251330 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2020-12-29
Clinical trial
A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of a Single Dose of ALXN1210 Administered Subcutaneously Compared to Intravenously in Healthy SubjectsStatus: Completed, Estimated PCD: 2017-07-18
Product
PF-07612577Product
Aztreonam-AvibactamClinical trial
An Uncontrolled, Single Centre, Healthy Volunteer, Phase II Proof-of-concept Trial Investigating MR-enterography Image Quality of Lumentin® 44, a New Egg Albumen Based Oral Small Bowel Filling Contrast Agent.Status: Completed, Estimated PCD: 2023-02-15
Product
Dimethyl FumarateClinical trial
A Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Tolerability, and Pharmacokinetics of BG00012 Administered With and Without 325 mg Aspirin in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2011-03-18
Clinical trial
Investigation of Pharmacokinetics and Absolute Oral Bioavailability of BI 1015550 Administered as an Oral Dose With an Intravenous Microtracer Dose of [14C]-BI 1015550 in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2023-03-28
Product
TacrolimusClinical trial
A PHASE 1, RANDOMIZED, OPEN-LABEL, 3-PERIOD, CROSSOVER, SINGLE-DOSE, 2-PART STUDY IN HEALTHY PARTICIPANTS TO INVESTIGATE THE EFFECT OF TABLET FORMULATION AND FOOD ON THE RELATIVE BIOAVAILABILITY OF PF-06821497Status: Completed, Estimated PCD: 2023-06-20
Clinical trial
A Phase I, First-In-Human, Randomized, Double-blind, Placebo-controlled, Single-Ascending-Dose Study of TT-00920 in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-06-18
Product
PlacebosClinical trial
A Randomized, Open-label, Parallel-group, Ethno-bridging Study Comparing the Pharmacokinetics and Safety of a Single Dose of UPB-101 in Healthy Japanese and Non-Japanese Non-East Asian AdultsStatus: Completed, Estimated PCD: 2023-04-07
Clinical trial
A Phase 1 Two-Part Study to Evaluate the Potential Drug Interactions Between ALXN2050 and Fluconazole, and Between ALXN2050 and Rifampin in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2021-08-04
Clinical trial
A Phase I Open Label Study to Assess the Single Dose Pharmacokinetics and Safety of Sublingual Administration of Tablets and Medicated Drops of Plant Cannabis ExtractStatus: Completed, Estimated PCD: 2022-10-24
Product
A5Product
B4Clinical trial
Safety, Tolerability and Immunogenicity of GLS-5310 DNA Vaccine Given as a Booster to Those Previously Vaccinated Against SARS-CoV-2Status: Active (not recruiting), Estimated PCD: 2023-01-10
Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study of Subcutaneously and Intravenously Administered ALXN1910 in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2023-02-07
Product
MVA-BN-FiloClinical trial
An Open Label, Fixed-sequence Study to Evaluate the Potential CYP3A4 Induction Effect of INDV-2000 Using Oral Midazolam as a Probe in Healthy Adults ParticipantsStatus: Completed, Estimated PCD: 2023-05-01
Product
LY3526318Product
PF-06755347Clinical trial
A Randomized, Parallel-Group, Placebo-Controlled, Double-Blind Phase 1/2a Study in Healthy HIV Uninfected Adults to Assess the Safety/Tolerability and Immunogenicity of 2 Different Prime/Boost Regimens; Priming With Trivalent Ad26.Mos.HIV and Boosting With Trivalent Ad26.Mos.HIV And Clade C Gp140 Plus Adjuvant or Priming With Tetravalent Ad26.Mos4.HIV and Boosting With Tetravalent Ad26.Mos4.HIV and Clade C Gp140 Plus AdjuvantStatus: Completed, Estimated PCD: 2022-04-25
Clinical trial
The Effect of Food on the Pharmacokinetics of a BI 425809 Tablet Formulation Administered as a Single Dose With and Without Food to Healthy Subjects (an Open-label, Randomised, Two-period, Two-sequence Crossover Trial)Status: Completed, Estimated PCD: 2022-12-28
Product
rFVIIaClinical trial
Pharmacodynamics Study of Enoxalow, Produced by Blau Farmacêutica S/A, Compared to Clexane, Produced by Sanofi-Aventis Farmacêutica Ltda, in Healthy Subjects After Subcutaneous Administration.Status: Completed, Estimated PCD: 2013-11-01
Clinical trial
Relative Bioavailability Comparison of BI 1015550 as the Intended Commercial Formulation (iCF) Versus Trial Formulation 2 and iCF With and Without Food Following Oral Administration in Healthy Subjects (an Open-label, Randomised, Single-dose, Three-way Crossover Trial)Status: Completed, Estimated PCD: 2022-09-30
Product
DRVClinical trial
A Randomized, Open-Label Study on the Effect of Nipocalimab on Vaccine Responses in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-10-04
Product
CefazolinProduct
LISTERINE COOL MINTClinical trial
An Open-label, Single-dose, Randomized, 2-period, 2-sequence Cross-over, Single-center Phase I Trial in Healthy Subjects to Assess the Bioequivalence of Tepotinib TF3 Administered as 5 Tablets of 100 mg Versus 2 Tablets of 250 mg Dose StrengthStatus: Completed, Estimated PCD: 2019-12-16
Clinical trial
Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BI 1839100 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2023-09-25
Product
Reference FormulationClinical trial
A Randomized, Double-blind, Placebo-controlled Study to Investigate the Safety, Tolerability and Pharmacokinetics of HS-10506 in Healthy SubjectsStatus: Not yet recruiting, Estimated PCD: 2023-12-24
Clinical trial
A Randomized, Double-blind, Placebo-controlled Phase 2a Study to Evaluate a Range of Dose Levels and Vaccination Intervals of Ad26.COV2.S in Healthy Adults Aged 18 to 55 Years Inclusive and Adults Aged 65 Years and Older and to Evaluate 2 Dose Levels of Ad26.COV2.S in Healthy Adolescents Aged 12 to 17 Years InclusiveStatus: Completed, Estimated PCD: 2022-03-09
Clinical trial
A Randomised, Double-blind, Placebo-controlled, Dose-escalation, Parallel-group, Single and Multiple Dosing Trial of NN90-1170 in Healthy Volunteers and Patients With Type 2 Diabetes to Assess Safety, Tolerability, Pharmacokinetics, and PharmacodynamicsStatus: Completed, Estimated PCD: 1999-11-01
Clinical trial
Relative Bioavailability of a Single Oral Dose of BI 894416 When Administered Alone or in Combination With Multiple Oral Doses of Itraconazole in Healthy Male Subjects (an Open-label, One-way Crossover Study)Status: Completed, Estimated PCD: 2018-12-14
Clinical trial
A Single Center, Randomized, Double Blinded PhaseI/IIa Exploratory Study to Evaluate Reactogenicity, Safety, Immunogenicity and Dose Response of a New Hepatitis B Vaccine in Human AdultStatus: Completed, Estimated PCD: 2015-05-28
Clinical trial
Phase II/III Double-blind, Randomized Clinical Trial With Active Vaccine Control to Evaluate the Safety, Immunogenicity, and Consistency of the Lots of Booster Dose of COVID-19 (Recombinant, Inactivated) Vaccine in Adults in BrazilStatus: Active (not recruiting), Estimated PCD: 2023-10-05
Product
BNT162b2Product
0.20% CHX gelProduct
PF-06882961Clinical trial
A Pharmacokinetic Study of Centella Asiatica in the ElderlyStatus: Active (not recruiting), Estimated PCD: 2019-11-30
Drug
LosartanClinical trial
Effect of Genetic Variation in the GLP-1 Receptor on Beta-cell Function During Fasting and Hyperglycemia in Nondiabetic HumansStatus: Recruiting, Estimated PCD: 2024-10-01
Product
Exendin-9,39Clinical trial
Single-Dose Fasting Bioequivalence Study of Oxybutynin Chloride Extended-Release Tablets (15 mg; Mylan)and Ditropan XL® Tablets (15 mg; ALZA) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-01-01
Product
Bromocriptine MesylateClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Rabeprazole Sodium Delayed-Release Tablets (20 mg; Mylan) to Aciphex® Tablets (20 mg; Eisai) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-08-01
Clinical trial
Effects of Fish Oil and Red Wine on Oxidative Stress Biomarkers: a Randomized Double-blinded Trial on the Modulation of the Eicosanoid and Isoprostane Pathways in Healthy Subjects by Omega-3 Polyunsaturated Fatty Acids and Red Wine.Status: Active (not recruiting), Estimated PCD: 2024-11-01
Product
Fish OilClinical trial
Physiologically Based Pharmacokinetic Modelling of Intravenous and Intranasal Formulations of Naloxone in Healthy Volunteers.Status: Recruiting, Estimated PCD: 2024-09-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Terbinafine Hydrochloride Tablets (250 mg; Mylan) and Lamisil® (250 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-03-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Midodrine HCl Tablets (5 mg; Mylan) and ProAmatine® Tablets (5 mg; Roberts) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-08-01
Product
AtenololProduct
MTX-463Product
CAB LAProduct
Verapamil HydrochlorideClinical trial
A 2-Part, Randomized, Phase I Study to Evaluate the Pharmacokinetics,Safety and Tolerability of Y-2 Sublingual Tablet in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2023-11-21
Clinical trial
Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human LungStatus: Recruiting, Estimated PCD: 2026-01-01
Product
DesonideProduct
Dilantin KapsealsClinical trial
Acute Dose-dependent Effects of DMT in Healthy Subjects: A Placebo-controlled Cross-over StudyStatus: Completed, Estimated PCD: 2024-03-08
Clinical trial
Effect of Cannabidiol on Microglial Activation and Central Pain-SensitizationStatus: Recruiting, Estimated PCD: 2024-08-31
Product
CapsaicinClinical trial
Effects of Oxytocin on the Functional Architecture of the Brain Before and After Prolonged Naturalistic Fear InductionStatus: Recruiting, Estimated PCD: 2025-05-31
Drug
Vitamin D3Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Oxybutynin Chloride Extended-release Tablets (5 mg; Mylan) and Ditropan XL® Tablets (5 mg; ALZA) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Metoprolol Tartrate Tablets (25 mg; Mylan) and Lopressor® (50 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Product
ZofranClinical trial
The Effect of Lixisenatide on the Effect of Pituitary HormonesStatus: Recruiting, Estimated PCD: 2023-10-31
Clinical trial
Serotonergic Modulation of Cognition, Emotion and Brain Activation in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-10-30
Product
JMKX000623Clinical trial
A Study of STAtins for Reducing Events in the Elderly (STAREE)Status: Active (not recruiting), Estimated PCD: 2025-12-01
Drug
AtorvastatinClinical trial
Cannabidiol and Autonomic Function in Individuals at RestStatus: Completed, Estimated PCD: 2021-11-29
Clinical trial
The Effects of Orally Administered Oxytocin on Behavioral and Neural Responses to Self Versus Other Touch DistinctionStatus: Recruiting, Estimated PCD: 2023-07-30
Clinical trial
Pharmacokinetics, Safety, and Efficacy of Fisetin - A Phase I and Pilot Phase IIa StudyStatus: Not yet recruiting, Estimated PCD: 2026-12-31
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Amlodipine and Benazepril HCl Capsules (10 mg/20 mg; Mylan) to Lotrel® Capsules (10 mg/20 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-05-01
Product
LorazepamProduct
Inderal LAProduct
[11-C]OMARProduct
PalceboProduct
Group 2: JW0104 + C2207Product
Group 3: C2207 + JW0104Product
Group 4: JW0104 + C2207Product
Group 5: JW0104 + C2207Product
Group 6: C2207 + JW0104Product
LEO 152020Clinical trial
Bioequivalence of Zongertinib Tablets From Two Different Manufacturers Following Oral Administration in Healthy Male and Female Subjects (an Open-label, Randomised, Single-dose, Two-period, Two-sequence Crossover Trial)Status: Not yet recruiting, Estimated PCD: 2024-06-24
Clinical trial
A Randomized, Open-label, Single Dose, Crossover Study to Compare the Pharmacokinetic Characteristics and Safety of JW0202 and C2202 or C2205 and JW0201 After Oral Administration in Healthy VolunteersStatus: Completed, Estimated PCD: 2023-11-20
Product
Food effect Cohort 1Product
Food effect_Cohort 2Product
RID-TDSClinical trial
A Randomized, Open-label, Crossover Phase 1 Study to Evaluate the Bioequivalence Following a Single Oral Dose Administration of SYR-472 25mg and 50mg Tablets in Healthy Adult Male SubjectsStatus: Completed, Estimated PCD: 2015-04-01
Product
T1Product
VerdinexorProduct
KH607 tabletsClinical trial
A Phase I, Open-label, Single Dose, Mass Balance Trial to Investigate Metabolism and Pharmacokinetics of BI 1291583 (C-14) Administered as Oral Solution in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2023-07-05
Product
CFTX-1554Clinical trial
A Single-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3819469Status: Completed, Estimated PCD: 2022-11-09
Clinical trial
A Phase I, Open-label, Single-dose, Single-arm Trial to Investigate Metabolism and Pharmacokinetics of BI 456906 (C-14) Administered Subcutaneously to (Otherwise) Healthy Male Volunteers With Normal Body Weight, Overweight or ObesityStatus: Completed, Estimated PCD: 2022-11-17
Product
DanicopanClinical trial
Single-center, Open-Label, 3-Period Crossover, Phase 1 Study to Evaluate the Pharmacokinetics of Hydrocodone Bitartrate Extended-Release (HC-ER) Capsules 50 mg When Co-Administered With Alcohol in Healthy Subjects Under Fasted ConditionsStatus: Completed, Estimated PCD: 2009-12-01
Clinical trial
A Two-Part, Open-Label Phase 1 Study to Evaluate the Effect of Food and Age on the Pharmacokinetics of DanicopanStatus: Completed, Estimated PCD: 2021-02-03
Clinical trial
A Phase 1, Open-Label, Drug Interaction Study to Investigate the Effect of Multiple Doses of Cyclosporine on the Pharmacokinetics of LY3502970 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-01-17
Clinical trial
A Phase 1, Open-Label Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of a Single Oral Dose of [14C]-ALXN2050 in Healthy Adult Male SubjectsStatus: Completed, Estimated PCD: 2021-08-23
Product
EB-203Clinical trial
Evaluate Efficacy of Milk Product Supplemented With Bioactives in Lowering Post Meal Glucose Response: an Acute Study in Chinese PopulationStatus: Completed, Estimated PCD: 2023-03-14
Clinical trial
A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Respiratory Combination Vaccine Candidates in Older AdultsStatus: Completed, Estimated PCD: 2023-09-27
Product
RSVpreFProduct
Xgeva®Product
TF2Product
IxekizumabProduct
LiraglutideProduct
BC222insulin lisproProduct
BI 1819479Product
RSVpreF + qIRVProduct
RodatristatProduct
A4Product
DA-5216-RProduct
ALXN1910Product
INDV-2000Clinical trial
A Phase 1, Randomized, Double-blind, Three-arm, Parallel Group, Single-dose Study to Compare the Pharmacokinetics and Safety of Three Formulations of Omalizumab (CT-P39, EU-approved Xolair, and US-licensed Xolair) in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-03-27
Product
Placebo matching BI 3802876Product
VER-01Clinical trial
A Randomized, Double-Blind and Nested Crossover (For Placebo and Moxifloxacin) Thorough QT Study to Evaluate the Effect of Rodatristat Ethyl, Rodatristat, and Its Major Metabolites on Cardiac Repolarization in Healthy VolunteersStatus: Completed, Estimated PCD: 2023-07-28
Clinical trial
A Phase 1, Open-Label Study to Characterize the Pharmacokinetics of Donanemab Following Intravenous Doses in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-07-14
Product
PonsegromabClinical trial
Six Month Clinical Efficacy of Virtually Supervised Mouthwash and Interdental Brushes: Effect on Plaque, Gingivitis and Oral MicrobiomeStatus: Completed, Estimated PCD: 2023-10-03
Clinical trial
The Effect of Multiple Oral Doses of BI 1015550 on Metabolism of Midazolam Administered Orally in Healthy Male Subjects (Open-label, Two-period Fixed Sequence Design Trial)Status: Completed, Estimated PCD: 2022-12-16
Clinical trial
An Open-Label, Single Dose Study to Evaluate the Pharmacokinetics of the Phase 2 Formulation of CORT125134 Capsules in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2016-04-27
Clinical trial
The Effect of Different Doses of Metformin or Furosemide on Rosuvastatin Pharmacokinetics Following Oral Administration in Healthy Male Subjects (an Open-label, Randomised, Single-dose, Six-way Crossover Study)Status: Completed, Estimated PCD: 2015-12-09
Product
AdalimumabProduct
JNJ-67835989Product
Midazolam-ratiopharm®Product
Ad26.COV2.SProduct
First Reference ConcorProduct
ANX1502Product
XC8Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of MZE001 to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-12-21
Product
SHR-2001Clinical trial
Brain-Behavior Markers of Reward and Drug Effects in Young AdultsStatus: Recruiting, Estimated PCD: 2025-06-30
Product
DiclofenacProduct
ClonidineClinical trial
Effects of Serotonin Transporter Inhibition on the Subjective Response to LSD in Healthy SubjectsStatus: Completed, Estimated PCD: 2024-02-20
Clinical trial
Acute Analgesic Effects of DMT on Experimentally Induced Acute Nociceptive Pain, Hyperalgesia and Allodynia in Healthy ParticipantsStatus: Not yet recruiting, Estimated PCD: 2025-01-30
Product
SecukinumabProduct
[11C]APP311Clinical trial
Assessing Target Engagement of Terazosin in Healthy AdultsStatus: Active (not recruiting), Estimated PCD: 2023-03-01
Product
Yellow Fever VaccineProduct
SufentanilClinical trial
Anthrax Vaccine Adsorbed: Human Reactogenicity and Immunogenicity Trial to Address Change in Route of Administration and Dose ReductionStatus: Completed, Estimated PCD: 2010-02-01
Product
Low dose Regular InsulinClinical trial
First-in-Human, Randomized, Double-Blind, Placebo-Controlled, Single Dose Escalation and Multiple Dose Escalation Phase I Clinical Trial of BG136 for Injection in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2023-09-05
Clinical trial
Mapping the Influence of Drugs of Abuse on Risk and Reward Circuits - MDMAStatus: Recruiting, Estimated PCD: 2024-11-01
Product
Single-Dose PropranololProduct
Single-dose placeboClinical trial
Bioequivalence Trial of Bilastine Tablets in Healthy Subjects in a Single-Center, Open, Randomized, Single-Dose, Double-Cycle, Double-Crossover Fasting StateStatus: Not yet recruiting, Estimated PCD: 2023-12-03
Product
Amino AcidClinical trial
An Open Label, Single Arm Pilot Study to Investigate the Safety and Tolerability of a Single 300mg Intravenous Dose of AVT16 in Healthy Adult Subjects Aged 18 to 55 Years InclusiveStatus: Recruiting, Estimated PCD: 2024-10-16
Product
AltrenoClinical trial
SSS40 A Single-center, Randomized, Double-blind, Placebo-controlled Phase I Clinical Study of Single-dose, Dose-escalation Safety, Tolerability, Pharmacokinetics, and Immunogenicity in Healthy Chinese Subjects.Status: Not yet recruiting, Estimated PCD: 2023-10-26
Clinical trial
Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluotriopride ([18F]FTP) by PET/CTStatus: Active (not recruiting), Estimated PCD: 2024-08-01
Product
LidocaineClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Meloxicam Tablets (15 mg; Mylan) and Mobic® Tablets (15 mg; Boehringer Ingelheim) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-09-01
Product
LY3454738Product
Camlipixant + RifampinProduct
BI 1595043Product
ImlunestrantProduct
BI 1584862Product
NEU-411Product
rosuvastatinProduct
RifabutinProduct
PirtobrutinibClinical trial
A Phase I, Open-label, Fixed-sequence, Drug Interaction Study to Investigate the Effect of Single and Multiple Oral Doses of LOXO-305 on the Pharmacokinetics of Multiple Oral Doses of Digoxin (P-Glycoprotein Substrate) in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-06-09
Clinical trial
Safety, Tolerability, and Pharmacokinetics of Two Dose Strengths of a Single Subcutaneous Dose of BI 655130 and One Single Intravenous Dose of BI 655130 in Healthy Male and Female Subjects (Open-label, Parallel Group Design)Status: Completed, Estimated PCD: 2018-01-10
Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of BGB-DXP604 Alone and in Combination With BGB-DXP593 in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-05-21
Product
ABL301Clinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Rising Oral Doses of BI 1323495 in Healthy Male Subjects (Single-blind, Partially Randomised, Placebo-controlled Parallel Group Design)Status: Completed, Estimated PCD: 2018-11-14
Product
BI 655130Product
BI 3802876Clinical trial
A Phase I, Single-Center, Open-Label, 3-Way Crossover, Randomized Single Dose Study to Evaluate the Food Effect on the Pharmacokinetics of TT-00420 Tablet and to Determine the Relative Bioavailability of TT-00420 Tablet Versus TT-00420 Capsule in Adult Healthy VolunteersStatus: Completed, Estimated PCD: 2021-03-07
Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic Profiles Following Single and Multiple Doses and Food Effect of CS32582 Capsules in Healthy Adult SubjectsStatus: Not yet recruiting, Estimated PCD: 2025-01-02
Product
Diclofenac SodiumClinical trial
Pharmacokinetics and Pharmacodynamic Effects of Different Single Oral Doses of BI 474121 in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2021-07-01
Product
GalantamineClinical trial
Investigation of Pharmacokinetics and Absolute Oral Bioavailability of BI 1291583 Administered as an Oral Dose With an Intravenous Microtracer Dose of [14C]-BI 1291583 in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2024-02-07
Clinical trial
A Clinical Pharmacological Study to Evaluate the Effects of Iron Supplements on the Pharmacokinetics of MT-6548 in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2018-09-30
Product
ABBV-CLS-7262Clinical trial
A Phase 1 Placebo-and Active-Controlled Crossover Study of the Potential for Cardiac Repolarization Effects Following Single Dose of ABBV-CLS-7262 in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
A Pilot Study Comparing LY3410738 Capsule and Tablet Formulations and Effect of a Low-fat Meal and a Proton Pump Inhibitor on the Single-dose Pharmacokinetics of LY3410738 Tablets in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-04-28
Clinical trial
A Phase I, Open-Label, Randomized, 2-Way Crossover Study to Investigate the Effect of Food on the Pharmacokinetics of a Single Oral Dose of Pirtobrutinib (LOXO-305) in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-03-08
Product
BI 1015550Clinical trial
Phase I, Open-Label, Single-sequence, Cross-Over Study of the Effect of Multiple Doses of Carbamazepine on Single-Dose Tepotinib Pharmacokinetics in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-05-06
Product
liraglutideClinical trial
A Randomized, Single-blind, Single-centre, Two-period, Cross-over Trial Investigating the Bioequivalence Between Completed Phase 2 and Planned Phase 3 Formulations of Liraglutide in Healthy SubjectsStatus: Completed, Estimated PCD: 2004-06-30
Product
KBP-7072Product
RSV VaccineClinical trial
Double Blind Placebo Controlled Dose Ranging Study for the Assessment of Safety, Tolerability and Pharmacokinetics of Single Ascending Oral Doses of GLPG0492 in Healthy Subjects and Open Relative Bioavailability Study of Oral Solution Versus Solid Formulation, Fasted and Fed, in Elderly SubjectsStatus: Completed, Estimated PCD: 2010-08-01
Product
Bardoxolone methylClinical trial
Safety, Tolerability, and Pharmacokinetics of Multiple Rising Oral Doses of BI 1815368 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Recruiting, Estimated PCD: 2024-06-14
Clinical trial
A Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Investigate Safety, Tolerability, and Pharmacokinetics of CK-0045 Following Subcutaneous Administration in Healthy Participants and Otherwise Healthy Participants With ObesityStatus: Completed, Estimated PCD: 2024-01-04
Product
STSA-1002Product
CK-0045Product
SpesolimabClinical trial
Effect of Rifampicin on the Pharmacokinetics of BI 409306 Following Oral Administration in Healthy Male Subjects (an Open-label, Two-period, Fixed Sequence Trial)Status: Completed, Estimated PCD: 2017-07-11
Product
TasimelteonClinical trial
Relative Bioavailability of Two Different Tablet Formulations of BI 685509 and Investigation of the Effects of Food and Esomeprazole on the Pharmacokinetics of BI 685509 Following Oral Administration in Healthy Male and Female Subjects (an Open-label, Randomised, Four-way Crossover Trial)Status: Completed, Estimated PCD: 2024-03-14
Product
ParoxetineClinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Rising Intravenous Doses of BI 765080 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel-group Design)Status: Completed, Estimated PCD: 2021-08-25
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED, DOSE-ESCALATING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE AND MULTIPLE INTRAVENOUS AND SUBCUTANEOUS DOSES OF PF-07264660 IN HEALTHY PARTICIPANTSStatus: Active (not recruiting), Estimated PCD: 2024-04-28
Clinical trial
A Randomised, Single-blind, Placebo-controlled Trial to Investigate Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BI 474121 Administered as Oral Solution and Tablets to Healthy Male Subjects (SRD Part), and a Randomised, Open-label, Single-dose, Three-way Cross-over Bioavailability Comparison of BI 474121 as Tablet Versus Oral Solution and Tablet With and Without Food (BA Part)Status: Completed, Estimated PCD: 2021-03-25
Clinical trial
A First-in-Human, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of CEL383 When Administered Intravenously to Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2024-01-17
Product
placeboProduct
moxifloxacinProduct
itraconazoleClinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of Subcutaneous ALXN1830 in Healthy ParticipantsStatus: Terminated, Estimated PCD: 2021-01-22
Clinical trial
Randomised, Double-blind, Placebo-controlled Parallel-group Proof of Mechanism Study to Assess the Pharmacokinetics and to Evaluate the Pharmacodynamic Effect of Different Single Oral Doses of BI 409306 in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2012-02-01
Product
PRA023Clinical trial
A Phase 1, Double-Blind, Placebo-Controlled, Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of PRA023 in Healthy Caucasian and Japanese Adult VolunteersStatus: Completed, Estimated PCD: 2022-08-31
Clinical trial
A Phase 1, 2-Part, Randomized, Double-Blind, Placebo Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BT-600 Single and Multiple Ascending Oral Doses in Healthy Adult SubjectsStatus: Recruiting, Estimated PCD: 2024-04-01
Product
Memantine Lactose-freeClinical trial
A Bioequivalence Study of Subcutaneous Injections of Mirikizumab Reference Solution Using Investigational 1-mL and 2-mL Prefilled Syringes and Mirikizumab Test Solution Formulation Using Investigational 1-mL and 2-mL Prefilled Syringes in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-05-25
Clinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Oral Doses of BI 1323495 Versus Placebo in Healthy Subjects, Including an Investigation of Drug-drug Interaction With Microdose Midazolam (Double-blind, Randomised, Placebo-controlled [Within Dose Groups] Trial)Status: Completed, Estimated PCD: 2021-03-05
Product
MidazolamProduct
LY3871801Clinical trial
A Safety, Tolerability, and Pharmacokinetic Study of Injections of LY3074828 Solution Using Investigational 1-mL Pre-filled Syringes and Investigational 1-mL Autoinjector in Healthy SubjectsStatus: Completed, Estimated PCD: 2019-10-04
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED, PARALLEL STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF MULTIPLE ASCENDING ORAL DOSES OF PF-07328948 IN HEALTHY ADULT PARTICIPANTSStatus: Recruiting, Estimated PCD: 2024-07-10
Clinical trial
A Single-Group, Open-Label, Single-Period, Phase 1 Study to Determine the Absolute Bioavailability of LY3502970 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2024-01-05
Product
[14C]-LY3502970Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Oxybutynin Chloride Extended-release Tablets (10 mg; Mylan) and Ditropan XL® Tablets(10 mg; ALZA) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-07-01
Clinical trial
A Double-Blind, Randomized, Placebo-Controlled, Parallel-Design, Study With an Open-Label Positive-Control, to Assess the Cardiac Safety of Oritavancin in Healthy VolunteersStatus: Completed, Estimated PCD: 2013-01-01
Product
LotionClinical trial
Single-Dose Fed Bioequivalence Study of Topiramate Sprinkle Capsules (25 mg; Mylan) and Topamax® Sprinkle Capsules (25 mg; Ortho-McNeil Neurologics) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-12-01
Clinical trial
Single-Dose In Vivo Bioequivalence and Wear Study of Fentanyl Transdermal System (25 µg/h; Mylan) and Fentanyl Transdermal System With Overlay (25 µg/h; Mylan) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-02-01
Clinical trial
A Phase I, Open-label, Fixed-sequence, Drug Interaction Study to Investigate the Effect of Multiple Oral Doses of LOXO-305 on CYP1A2, CYP2C9, and CYP2C19 Substrates Using a Probe Drug Cocktail in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-04-15
Clinical trial
A Phase 1, Open-Label, Food Effect, And Dose Proportionality Study With Omaveloxolone In Healthy VolunteersStatus: Completed, Estimated PCD: 2018-11-20
Product
omaveloxoloneClinical trial
A Double-blind, Placebo-controlled, Randomized, Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Orally Administered DA-7503 After Single and Multiple Ascending Dose Regimens in Healthy Adult and Elderly ParticipantsStatus: Not yet recruiting, Estimated PCD: 2025-05-31
Product
BI 3006337Clinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Rising Subcutaneous Doses and Multiple Subcutaneous Doses Over 6 Weeks of BI 3006337 in Healthy Male Japanese Subjects (Single-blind, Randomised Within Dose Groups, Placebo-controlled, Parallel Group Design)Status: Recruiting, Estimated PCD: 2024-10-18
Clinical trial
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Intravenous Doses of BI 655130 (Double-blind, Partially Randomised Within Dose Groups, Placebo-controlled Parallel Group Design) and One Single Intravenous Dose of BI 655130 (Single-blind, Partially Randomised, Placebo-controlled) in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2017-08-01
Product
Albuterol SulfateClinical trial
Relative Bioavailability of a Mirikizumab Test Formulation Compared to the Reference Formulation in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-01-11
Clinical trial
A PHASE 1, RANDOMIZED, OPEN-LABEL STUDY IN HEALTHY PARTICIPANTS TO ESTIMATE THE BIOAVAILABILITY OF TWO NEW ENCORAFENIB FORMULATIONS RELATIVE TO THE CURRENT FORMULATION AND TO EVALUATE THE EFFECT OF A PROTON-PUMP INHIBITOR ON ENCORAFENIB PLASMA PHARMACOKINETICSStatus: Completed, Estimated PCD: 2022-09-30
Clinical trial
Relative Bioavailability of Rosuvastatin (Part 1) and Dabigatran (Part 2) Given Alone and Together With BI 1323495 in Healthy Male Subjects (Open, Single-dose, Randomised, Two-period Crossover Design in Each Trial Part)Status: Completed, Estimated PCD: 2020-09-23
Clinical trial
Phase 1, Open-label, Parallel, 2-arm, Fixed-sequence Study to Investigate the Effect of Coadministration of CYP3A4 Inhibitor and CYP3A4 Inducer on the Pharmacokinetics, Safety, and Tolerability of KBP-5074 in Healthy SubjectsStatus: Completed, Estimated PCD: 2020-11-30
Product
Listerine Total Care ZeroClinical trial
A Single and Multiple-Ascending Dose Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetics of LY3938577 in Healthy Participants and Participants With Type 2 Diabetes MellitusStatus: Recruiting, Estimated PCD: 2024-08-01
Clinical trial
Comparing Direct and Indirect Detection Methods Following Multiple Routes of Testosterone administration-an Anti-doping PerspectiveStatus: , Estimated PCD: 2024-08-01
Product
DuragesicClinical trial
Single-Dose In Vivo Bioequivalence and Wear Study of Fentanyl Transdermal System (25 µg/h; Mylan) and Fentanyl Transdermal System With Overlay (25 µg/h; Mylan) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-10-01
Product
WAL0921Product
LY4100511Clinical trial
A Placebo-controlled, Phase 1, Participant- and Investigator-blinded, Single- and Multiple- Dose Study to Evaluate Safety, Tolerability, and Pharmacokinetics of LY4100511 (DC-853) in Healthy Asian and Non-Asian ParticipantsStatus: Not yet recruiting, Estimated PCD: 2024-05-30
Clinical trial
Pharmacokinetics, Safety, and Tolerability of BI 685509 in Subjects With Severe Liver Impairment (Child-Pugh Classification C) as Compared to Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-10-01
Product
Avenciguat (BI 685509)Clinical trial
A Phase 1, Randomized, Participant- and Investigator-Blind, Placebo-Controlled, Single- and Multiple-Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3541860 in Healthy Japanese and Non-Japanese ParticipantsStatus: Completed, Estimated PCD: 2023-12-27
Product
BI 1569912Clinical trial
A Parallel-Group, Single-Dose, Phase 1, Open-Label Study to Investigate the Pharmacokinetics of LY3437943 in Participants With Hepatic Impairment Compared With Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2024-10-01
Clinical trial
The Effect of Multiple Doses of BI 1569912 on the Single-dose Pharmacokinetics of Repaglinide, Midazolam and Bupropion Following Oral Administration in Healthy Male and Female Subjects (an Open-label, 2-period Fixed-sequence Trial)Status: Not yet recruiting, Estimated PCD: 2024-08-24
Product
TopiramateProduct
BI 765080Clinical trial
An Evaluation of The Absolute Bioavailability of TH104Status: Active (not recruiting), Estimated PCD: 2024-02-11
Clinical trial
A Clinical Study on Absorption, Metabolism, and Excretion of [14C]HSK31679 in Healthy Adult Male Chinese Subjects - Mass Balance and Biotransformation of [14C]HSK31679 in HumanStatus: Active (not recruiting), Estimated PCD: 2023-12-21
Clinical trial
Single-Dose Food in Vivo Bioequivalence Study of Valacyclovir Hydrochloride Tablets (1000 mg; Mylan) to Valtrex® Tablets (1000 mg; GlaxoSmithKline) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-08-01
Product
ValtrexClinical trial
A PHASE 1, OPEN-LABEL, TWO-PERIOD, FIXED SEQUENCE STUDY TO INVESTIGATE THE EFFECT OF A PROTON PUMP INHIBITOR ON THE PHARMACOKINETICS OF SISUNATOVIR IN HEALTHY ADULT PARTICIPANTSStatus: Recruiting, Estimated PCD: 2024-06-16
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MinoxidilProduct
semaglutideProduct
[14C]-HU6Clinical trial
A Randomized, Open Label, Single Dose, Crossover Clinical Trial to Evaluate the Pharmacokinetic Characteristics and Safety After Administration of a Fixed-dose Combination Drug of HCP2303 and Co-administration of RLD2302 and RLD2102 in Healthy Volunteers Under Fasting ConditionsStatus: Not yet recruiting, Estimated PCD: 2024-06-08
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A Phase 1, Single-Center, Open-Label, 3-Cohort, Fixed-Sequence, Drug-Drug Interaction Study To Assess The Pharmacokinetics Of LY4100511 (DC-853) When Orally Administered Alone, When Coadministered With Itraconazole, Fluconazole, Or Carbamazepine In Healthy Adult ParticipantsStatus: Not yet recruiting, Estimated PCD: 2024-06-17
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LetrozoleClinical trial
A Phase 1, 2-part, Open-label, Fixed-sequence Study Evaluating Potential Drug-drug Interactions Between Gemfibrozil (Part 1) or Dabigatran Etexilate (Part 2) and Camlipixant (BLU-5937) 50 mg Tablet in Healthy Participants Under Fasting ConditionsStatus: Completed, Estimated PCD: 2023-10-13
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Relative Bioavailability of a Single Oral Dose of BI 1323495 When Administered Alone or in Combination With Multiple Oral Doses of Itraconazole in Healthy Male Subjects (an Open-label, One-way Crossover Study)Status: Completed, Estimated PCD: 2019-09-06
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A Phase 1 Study to Evaluate Safety, Tolerability, and Food-Effect Following Administration of ABBV-CLS-7262 in Healthy VolunteersStatus: Completed, Estimated PCD: 2024-01-30
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IclepertinProduct
TK-254RXClinical trial
A 3-Part, Randomized, Placebo-controlled, Double-blind, Single Ascending Dose Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-69095897 in Healthy ParticipantsStatus: Terminated, Estimated PCD: 2023-01-27
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A PHASE 1, RANDOMIZED, OPEN-LABEL, SINGLE DOSE STUDY TO INVESTIGATE THE PHARMACOKINETICS, PHARMACODYNAMICS, SAFETY AND TOLERABILITY OF VUPANORSEN ADMINISTERED SUBCUTANEOUSLY TO HEALTHY CHINESE ADULTSStatus: Completed, Estimated PCD: 2021-10-19
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Single- and Multiple-Ascending Dose, Safety, Tolerability, and Pharmacokinetic Study With LY3154885 in Healthy SubjectsStatus: Terminated, Estimated PCD: 2020-02-09
Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single and Multiple-Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RAY1225Status: Recruiting, Estimated PCD: 2024-05-01
Clinical trial
A Randomized, Double Blind, Three-Arm, Parallel Group, Pharmacokinetic Similarity Study in Healthy Male Subjects to Evaluate Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of LY06006 Versus US Prolia and EU Prolia by Single-Dose Subcutaneous InjectionStatus: Completed, Estimated PCD: 2023-03-14
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Effect of Injection Site on the Relative Bioavailability of Single Dose of LY3209590 and Evaluation of Absolute Bioavailability of LY3209590 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-06-27
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LotensinProduct
LazertinibProduct
JNJ-88260237Clinical trial
A Double-blind, Randomized, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-88260237 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-05-09
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OtezlaProduct
MBX 2109Product
Ir-CPIClinical trial
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Doses of BI 655088 Administered by Intravenous Infusion in Healthy Male Subjects (Single-blind, Partially Randomised Within Dose Groups, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2019-02-14
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A Phase 1, Open-label, Drug Interaction Study to Investigate the Effect of Multiple Doses of Clarithromycin on the Pharmacokinetics of LY3502970 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-11-03
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A Phase 1 Open-label Single Ascending Dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of JNJ-77474462 (Bermekimab) in Healthy Chinese Participants Following Subcutaneous AdministrationStatus: Withdrawn, Estimated PCD: 2023-11-20
Clinical trial
A Phase 1, Single Centre, Open Label, Crossover Study in Healthy Volunteers Using Scintigraphy to Evaluate the Gastrointestinal Behaviour of EDP1815 Oral Dosage Forms.Status: Completed, Estimated PCD: 2022-08-11
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BetrixabanProduct
RLD2002Clinical trial
A Randomized, Open-label, Single-Dose, Parallel Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HCP1803 in Healthy Male Volunteers.Status: Completed, Estimated PCD: 2023-03-20
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Ad26.RSV.preFProduct
HeparinProduct
BI 730357Clinical trial
Partially-blind, Randomized, Parallel Group, Placebo and Active Comparator-controlled Phase I Clinical Trial to Evaluate the Photosensitivity Potential of BI 730357Status: Completed, Estimated PCD: 2020-09-09
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TofacitinibProduct
MT-6345Clinical trial
An Open Label, Randomized, Single Dose, Cross-over ,Two-group Study to Evaluate the Pharmacokinetics and Safety of DA-1229_01 2.5/500mg in Healthy Subjects at Fed StateStatus: Not yet recruiting, Estimated PCD: 2023-04-07
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RLD2203Clinical trial
AN INTERVENTIONAL, PHASE 1, OPEN-LABEL, FIXED SEQUENCE, 2-PERIOD STUDY TO ESTIMATE THE EFFECT OF MULTIPLE DOSES OF ITRACONAZOLE ON THE PHARMACOKINETICS OF SINGLE DOSE ARV-471 IN THE FED CONDITION IN HEALTHY ADULT MALES, AND FEMALES OF NONCHILDBEARING POTENTIALStatus: Completed, Estimated PCD: 2023-05-22
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IOA-289Product
RupatadineClinical trial
A Randomized, Open, Single-dose, Crossover-design, Phase I Study to Evaluate Bioequivalence After Co-administration of ALO 25 mg and MET XR 1,000 mg or Administration of CT-L01 25/1,000 mg in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-06-21
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CT-L01Clinical trial
Formulation Selection and Subsequent Optimization of Oral Formulations of BI 685509 in Healthy Male Subjects (Open-label, Randomized, Single-dose Design Study in up to Three Parts; Trial Part 1: Five-period Crossover; Optional Trial Parts 2 & 3: Fourperiod Crossover)Status: Completed, Estimated PCD: 2022-02-07
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T7Product
R3Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Lamotrigine Tablets (25 mg; Mylan) to Lamictal® Tablets (25 mg; GSK) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-08-01
Clinical trial
A Phase 1 Study to Evaluate the Safety and PK/PD Drug-drug Interaction Between Epaminurad and Naproxen or to Assess the Safety and Multiple-Dose PK/PD Characteristics of Epaminurad in Healthy VolunteersStatus: Not yet recruiting, Estimated PCD: 2024-08-01
Clinical trial
Modulating Celecoxib Induced Blood Pressure Changes by Timed Administration of Aspirin and the Human ChronobiomeStatus: Not yet recruiting, Estimated PCD: 2026-05-01
Clinical trial
Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2025-06-30
Clinical trial
Single-Center, Open, Randomized, Single-Dose, Completely Repeated Crossover Bioequivalence Study to Evaluate the Effects of the Test/Reference Preparation, Entacapone,Levodopa and Carbidopa Tablets (II) in Healthy Adult SubjectsStatus: Not yet recruiting, Estimated PCD: 2023-09-07
Clinical trial
A Dose-response Study Examining the Contribution of GLP-1 Receptor Signaling to Glucagon-stimulated Insulin SecretionStatus: Completed, Estimated PCD: 2022-06-14
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Nicotinamide RibosideProduct
IndomethacinClinical trial
Open-label, Randomised, Two-way Crossover Study to Assess the Effect of Once Daily Itraconazole on the Pharmacokinetics of BI 409306 After a Single Oral Dose in Healthy Male Volunteers Genotyped as Poor and Extensive Metabolizers of CYP2C19Status: Completed, Estimated PCD: 2015-01-07
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LevothroidClinical trial
Renal Microvessel Imaging for Characterization of Chronic Kidney DiseaseStatus: , Estimated PCD: 2028-04-01
Clinical trial
Effect of Ileocolic-released Conjugated Bile Acid on Satiety, Entero-Endocrine Cell Function, and Body Weight in Patients With Obesity and Abnormal Satiety PhenotypeStatus: , Estimated PCD: 2026-05-01
Clinical trial
Effects of Psilocybin-facilitated Experience on the Psychology and Effectiveness of Professional Leaders in ReligionStatus: Active (not recruiting), Estimated PCD: 2024-05-01
Clinical trial
A Phase 1, Single and Multiple Subcutaneous Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics of TB001 Injection in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-08-23
Clinical trial
Impact of Repetitive Transcranial Magnetic Stimulation (rTMS) of Limbic Brain Circuitry in Stress Modulation in a Healthy PopulationStatus: Withdrawn, Estimated PCD: 2023-04-10
Clinical trial
Single-Dose Fasting Bioequivalence Study of Doxycycline Monohydrate Tablets (150 mg; Mylan) and Adoxa Tablets (150 mg; Par) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-03-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Clopidogrel Bisulfate Tablets (75 mg; Mylan) to Plavix® Tablets (75 mg; Bristol-Myers Squibb/Sanofi) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-12-01
Clinical trial
Effects of Intranasal Oxytocin on Fear Processing in Naturalistic ContextsStatus: Recruiting, Estimated PCD: 2025-03-31
Clinical trial
Is Nociceptive Processing Evoked by Heat Homeostatically Regulated: A Contact-heat Evoked Potentials StudyStatus: Completed, Estimated PCD: 2024-03-04
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Capsaicin 8% PatchClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Glimepiride Tablets (1 mg; Mylan) to Amaryl® Tablets (1 mg; Aventis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-11-01
Clinical trial
A Double-Blind, Randomized, Placebo-Controlled, First-in-Human Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Orally Administered DF-003 Following Single (Part 1) and Multiple (Part 2) Ascending Doses in Healthy SubjectsStatus: Active (not recruiting), Estimated PCD: 2024-03-23
Clinical trial
Randomized Single Dose Crossover Replicate Comparative Bioavailability Study of Clarithromycin 250 mg Tablets in Healthy Male and Female Volunteers Under Fasted ConditionsStatus: Completed, Estimated PCD: 2004-06-01
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Sertraline HydrochlorideClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Cetirizine HCl Tablets (10 mg; Mylan) and Zyrtec® Tablets (10 mg; Pfizer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
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IsoproterenolProduct
gp140 HIV Bivalent VaccineClinical trial
A Randomised, Double-blind, Placebo Controlled, Parallel Group Study in Healthy Adult Volunteers to Determine the Tolerability and Safety of Pyronaridine (PYR) Co-administered With Piperaquine (PQP) Under Fasted ConditionsStatus: Completed, Estimated PCD: 2022-05-31
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Single dose placeboClinical trial
A Phase 1, Open-label, Randomized, Two-Part Study to Assess the Safety and Pharmacokinetics of Tablet and Capsule Formulations of HU6 in Healthy Subjects.Status: Not yet recruiting, Estimated PCD: 2024-10-14
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Reference Drug or Test DrugProduct
TYRA-300-B01Clinical trial
Safety, Tolerability and Pharmacokinetics of Multiple Rising Oral Doses of BI 3000202 in Healthy Male and Female Subjects (Double-blind, Randomised, Placebo-controlled, Parallel Group Design) and Evaluation of Midazolam Interaction in Healthy Male and Female Subjects (Nested, Open, Fixed-sequence, Intra-individual Comparison)Status: Recruiting, Estimated PCD: 2024-09-27
Clinical trial
An Open-Label Study to Assess the Drug-Drug Interaction Potential of a Single 1200 mg IV Dose of Orbactiv (Oritavancin) Co-Administered With Warfarin in Healthy Subjects.Status: Completed, Estimated PCD: 2015-09-01
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RSS0393Clinical trial
A Phase Ib, Randomized, Double-Blind, Placebo Controlled, Sequential Study of Single Oral Doses of M5717 to Explore the Chemoprophylactic Activity of M5717 in a Controlled PISPZ Challenge Model in Healthy ParticipantsStatus: Completed, Estimated PCD: 2021-08-18
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TopamaxClinical trial
Thorough QT Study to Evaluate the Effects of BI 1015550 as Single Doses Following Oral Administration on Cardiac Safety Parameters (Double-blind, Randomized, Placebo-controlled, Five-period Crossover, With Open-label Moxifloxacin as Positive Control) in Healthy Male and Female SubjectsStatus: Recruiting, Estimated PCD: 2024-07-30
Clinical trial
A Randomized, Open-label, Single Dose, 2x4 Crossover Study to Evaluate the Safety and Pharmacokinetic Characteristics After Co-administration of JW0101 and C2101 and Administration of JW0102 in Healthy Volunteers Under Fasting ConditionsStatus: Completed, Estimated PCD: 2023-07-10
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SimvastatinProduct
Sodium BicarbonateClinical trial
An Open Label, Single Arm, Single Dose Study to Evaluate the Pharmacokinetics and Safety and Tolerability of MGTA 145 in Subjects With Normal Estimated GFR and Varying Degrees of Renal ImpairmentStatus: Completed, Estimated PCD: 2020-03-24
Clinical trial
A Phase 1, Randomized, Study in Healthy Volunteers to Assess Relative Bioavailability and Effect of Food on Capsule and Tablet Formulations of TP-3654Status: Completed, Estimated PCD: 2023-08-01
Clinical trial
A Randomized, Open-label, Multiple-dose, 6×3 Crossover Clinical Trial to Investigate the Pharmacokinetic Drug Interaction and Safety of JW0104 and C2207 in Healthy AdultsStatus: Completed, Estimated PCD: 2023-12-23
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REGN15160Clinical trial
The Effect of Multiple Oral Doses of Bosentan on the Steady State Kinetics of BI 425809 After Oral Administration to Healthy Male Subjects (an Open-label, Two-period Fixed Sequence Trial)Status: Completed, Estimated PCD: 2023-05-26
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A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED, 4-PERIOD, CROSSOVER, FIRST-IN-HUMAN STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF SINGLE ASCENDING ORAL DOSES OF PF-07328948 ADMINISTERED TO HEALTHY ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2023-05-03
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JNJ-77242113Clinical trial
A Phase I, Open-label, Two-arm, Non-randomised Trial to Investigate the Metabolism and Pharmacokinetics of a Single Dose of BI 764198 (C-14) Administered as Oral Solution Using Two Different Approaches in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2023-11-09
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BI 764198Product
ID120040002Clinical trial
Bioequivalence Study of Dapagliflozin 10 mg Film-coated Tablet Produced by PT Dexa Medica in Comparison With the Comparator Drug (Forxiga® 10 mg Film-Coated Tablet, Manufactured by AstraZeneca Pharmaceuticals LP, USA for AstraZeneca Pharmaceuticals Co. Ltd., China Imported by PT AstraZeneca Indonesia, Indonesia)Status: Completed, Estimated PCD: 2023-03-15
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A Phase 1, Single Ascending Dose and Multiple Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ABX1100 in Normal Healthy VolunteersStatus: Recruiting, Estimated PCD: 2024-07-31
Clinical trial
An Open Label, Randomized, Single Dose, Cross-over ,Two-group Study to Evaluate the Pharmacokinetics and Safety of DA-1229_01 5/1000mg in Healthy Subjects at Fed StateStatus: Not yet recruiting, Estimated PCD: 2023-04-28
Clinical trial
Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 1015550 in Healthy Japanese Male Subjects (Double-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2018-08-24
Clinical trial
A Randomized, Double-Blind, Placebo-Controlled, Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Oral Doses of BMB-101 in Fed and Fasted Adult Healthy Human VolunteersStatus: Completed, Estimated PCD: 2023-05-04
Clinical trial
An Open-label, Single-sequence, Drug-drug Interaction Study to Evaluate the Effect of Steady-state Carbamazepine on the Single-dose Pharmacokinetics of Erdafitinib Tablets in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-06-14
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JNJ-64251330Product
PF-06650833Clinical trial
AN OPEN LABEL, PHASE 1, TWO-ARM STUDY TO ASSESS TARGET OCCUPANCY AND FUNCTIONAL INHIBITION OF JAK3 AND TEC KINASES BY SINGLE DOSES OF RITLECITINIB IN HEALTHY ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2022-01-14
Clinical trial
A PHASE 1, OPEN-LABEL, RANDOMIZED, CROSSOVER, SINGLE DOSE STUDY TO ESTIMATE THE RELATIVE BIOAVAILABILITY OF VARIANT 12.2 MG TAFAMIDIS FREE ACID TABLETS AND PROPOSED COMMERCIAL 12.2 MG TAFAMIDIS FREE ACID TABLETS ADMINISTERED UNDER FASTED CONDITIONS IN HEALTHY ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2022-10-28
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HHT120Clinical trial
The Effect of Imlunestrant on CYP2C8, CYP2C19, CYP2D6, P-gp, and BCRP Activity and the Effect of P-gp Inhibition on Imlunestrant Pharmacokinetics in Healthy Women of Non-childbearing PotentialStatus: Completed, Estimated PCD: 2022-11-02
Clinical trial
An Open-Label, Single-Dose Study to Evaluate the Pharmacokinetics of MCI-186 in Subjects With Severe Hepatic Impairment Compared to Subjects With Normal Hepatic FunctionStatus: Completed, Estimated PCD: 2019-03-25
Clinical trial
Bioequivalence of Lasmiditan Oral Disintegrating Tablet Compared to Current Immediate-Release Tablet Formulation to Support Treatment of MigraineStatus: Completed, Estimated PCD: 2021-07-24
Clinical trial
Disposition of [¹⁴C]-LY3337641 Following Oral Administration in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2016-11-01
Product
BrexpiprazoleProduct
MCI-186Product
14C TirzepatideClinical trial
A Randomized, Open-label, Three-period, Multiple Dosing Crossover Clinical Trial to Evaluate the Influence of Tegoprazan on the Pharmacodynamics of Clopidogrel in Healthy SubjectsStatus: Not yet recruiting, Estimated PCD: 2024-11-01
Clinical trial
A Open-label, Single-dose, Phase 1 Study to Compare and Evaluate the Safety and Pharmacokinetics According to the Dose of Camostat Mesylate in Healthy VolunteersStatus: Completed, Estimated PCD: 2021-03-16
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KetamineClinical trial
A Phase I, Randomized, Double-blind, Placebo-controlled, Ascending Single Dose and Multiple Dose Study of TT-00920 in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-06-06
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A1Clinical trial
Phase 1 Assessment of Pharmacokinetics and Pharmacodynamics of Two Epoetin Alfa, Human Recombinant Epoetin (Blau Farmacêutica) and Eprex (Janssen-Cilag), After Multiple Dose, Intravenous Administration in Healthy Subjects: a Randomized Parallel Study.Status: Completed, Estimated PCD: 2013-10-31
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A First-in-human, Randomized, Double-blinded, Placebo- Controlled, Two-part Study to Assess Safety/Tolerability and Pharmacokinetics of Single- and Multiple-ascending Doses and Food Effect of GFH312 in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-05-23
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MilvexianProduct
Ad26.ZEBOVClinical trial
An Open-label, Randomized, Crossover Study to Evaluate the Pharmacokinetic and Pharmacodynamic Interaction Between Tegoprazan and Novel Oral Anticoagulants (NOACs) After Multiple Oral Dosing in Healthy VolunteersStatus: Completed, Estimated PCD: 2023-07-17
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A Phase 1, First-in-human, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Food Effect, and Pharmacodynamics Following a Single Oral Dose of IA-14069 in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-09-08
Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single-Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of NM8074 Administered Intravenously to Healthy SubjectsStatus: Completed, Estimated PCD: 2022-06-15
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Ad26.Mos.HIVProduct
Clade C gp140Clinical trial
An Open Label, Randomized, Single Dose, Two Way Crossover, Bioavailability Study of a Combination Formulation of Decitabine/Tetrahydrouridine (2.5 mg/100 mg) Modified Release Capsules in Healthy, Fasting, Male AdultsStatus: Recruiting, Estimated PCD: 2023-05-16
Clinical trial
A Two-Part, Open-Label, Randomized, Placebo-Controlled Crossover Study to Assess the Reversal of the Anticoagulant Effects of Milvexian by 4-Factor Prothrombin Complex Concentrate (4F-PCC) (Part 1) and Recombinant Human Factor VIIa (rFVIIa) (Part 2) in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-06-07
Clinical trial
An Open-Label, Single-Dose Study to Assess the Absolute Oral Bioavailability and Pharmacokinetics of JNJ-42847922 (Seltorexant) Administered as Oral Tablet and an Intravenous Microdose of 14C-seltorexant in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-03-01
Clinical trial
An Open-Label Study to Investigate the Regional Brain Kinetics of the Positron Emission Tomography Ligand [18F]-JNJ-70099731 in Healthy Male ParticipantsStatus: Completed, Estimated PCD: 2022-02-01
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CM326Product
TUR03Clinical trial
A Phase 1, Randomzied, Double-blind, Third-party Open Placebo-controlled, Dose Escalating Study To Evaluate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Single Intravenous And Multiple Subcutaneous And Intravenous Doses Of Pf-06480605 In Healthy SubjectsStatus: Completed, Estimated PCD: 2015-03-01
Clinical trial
AN INTERVENTIONAL, PHASE 1, OPEN-LABEL, FIXED-SEQUENCE, 2-PERIOD STUDY TO EVALUATE THE EFFECT OF A SINGLE ORAL DOSE OF ARV-471 (PF-07850327) ON THE PHARMACOKINETICS OF DABIGATRAN IN HEALTHY PARTICIPANTSStatus: Completed, Estimated PCD: 2023-04-19
Clinical trial
A Phase 1, Open-Label, Randomized, Single-Dose, Parallel-Group Study to Evaluate the Food Effect on the Pharmacokinetics of TP-05 Under Fed and Fasted Conditions in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-05-30
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XEN-101Clinical trial
A Single-center, Open-label, Three-period, Fixed-sequence Design Study to Investigate the Effect of Daridorexant on the Pharmacokinetics of Dabigatran and Rosuvastatin in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-09-17
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Flavoxate HydrochlorideProduct
Adjuvanted Multimeric-001Product
Phosphate Buffered SalineProduct
Adjuvanted PBSClinical trial
A Randomized, Double-Blind, Single and Multiple Ascending Dose Study to Assess the Safety and Pharmacokinetics of Niclosamide in Healthy AdultsStatus: Completed, Estimated PCD: 2021-10-13
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JNJ-70033093Product
HS-10506Clinical trial
Double-blind, Randomized, Dose-response Study of RE02 in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2023-12-01
Clinical trial
The Effect of Multiple Doses of BI 425809 on the Pharmacokinetics of Multiple Doses of a Combination of Ethinylestradiol and Levonorgestrel Following Oral Administration in Healthy Premenopausal Female Subjects (an Open-label, Two-period, Fixed Sequence Design Trial With run-in Period)Status: Completed, Estimated PCD: 2023-10-04
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REGN5381Clinical trial
A Phase I (First-in-human) Randomized, Double-blind, Placebo Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CAN10, an Anti-IL1RAP Monoclonal Antibody, in Healthy Subjects and in Subjects With Mild to Moderate Plaque Psoriasis.Status: Recruiting, Estimated PCD: 2025-04-24
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CAN10Clinical trial
Pharmacokinetics, Safety and Tolerability of Doses of BI 1015550 in Healthy Chinese Male and Female Subjects (Open-label, Parallel Group Design)Status: Completed, Estimated PCD: 2023-03-16
Clinical trial
Relative Bioavailability of Empagliflozin/Metformin Fixed-dose Combination - Empagliflozin 12.5 mg + Metformin 850mg (Boehringer Ingelheim) Coated Tablet Versus Jardiance® 10mg (Reference 1: Boehringer Ingelheim) Coated Tablet and Glifage® 850mg (Reference 2: Merck S / A. ) Coated Tablet, Administered Together in Healthy Male and Female Subjects Under Fed Conditions: an Open-label, Randomised, Single-dose, Two-way Crossover StudyStatus: Completed, Estimated PCD: 2021-08-06
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EmpagliflozinProduct
Glifage®Clinical trial
A Phase 1 Safety, Tolerability and Pharmacokinetic Study of R-Idazoxan HCl Extended-Release (TR-01-XRR), S-Idazoxan HCl Extended-Release (TR-01-XRS) and Racemic Idazoxan HCl Extended-Release (TR-01-XR) in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2024-03-01
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PRA023 IV High DoseProduct
AprepitantClinical trial
Consciousness and Psilocybin Effects on Well-Being (The CoPE Study): Pilot PhaseStatus: , Estimated PCD: 2025-06-01
Clinical trial
A Randomized, Open-label, Two-period, Cross-over Trial to Evaluate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Injection Compared With Xultophy® in Healthy Chinese SubjectsStatus: Recruiting, Estimated PCD: 2024-06-16
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Randomized Clinical Trial on the Immediate Antibacterial Effect and Substantivity of a Single Application of a New Chlorhexidine Gel on Oral Biofilm and SalivaStatus: Completed, Estimated PCD: 2023-06-30
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Intranasal insulinClinical trial
Phase 1, Dose-Dependent Effect of Intranasal Insulin in Humans Using Functional MRIStatus: Completed, Estimated PCD: 2024-02-22
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PhenylephrineClinical trial
Losartan Modulates Neural Responses to Looming Visual Stimuli: An Eye-tracking StudyStatus: Recruiting, Estimated PCD: 2025-06-01
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Study of Mylan Pharmaceuticals Inc. and Novartis Pharmaceuticals Corporation (Parlodel®) 5 mg Bromocriptine Mesylate Capsules Following a 10 mg Dose in Healthy Adult Volunteers Under Fed ConditionsStatus: Completed, Estimated PCD: 2007-06-01
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ParlodelProduct
[18F]PBR111Product
Balsalazide DisodiumClinical trial
Acute Effects of R- and S-MDMA in Healthy SubjectsStatus: Completed, Estimated PCD: 2024-01-13
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Terbinafine HydrochlorideProduct
ProAmatine TabletsProduct
Early Dinner tracerDrug
VarlilumabProduct
DexlansoprazoleProduct
N,N-DimethyltryptamineProduct
EcopipamClinical trial
A Phase 1, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Single-Ascending Dose Study of LY3872386 in Healthy Participants, a Multiple-Ascending Dose Study of LY3872386 in Patients With Atopic Dermatitis, and an Open-Label Multiple-Dose Evaluation of the Safety and Tolerability of Prednisone in Healthy Participants.Status: Recruiting, Estimated PCD: 2026-01-01
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rhNGFProduct
ZonegranProduct
Benicar HCTClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Olmesartan Medoxomil Tablets (40 mg; Mylan) to Benicar® Tablets (40 mg; Sankyo) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-12-01
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Placebo with C1K 600mgProduct
TP-03Clinical trial
A Phase 1, Open-Label, Drug-Drug Interaction, Study to Evaluate the Effect of ASC42 on the Pharmacokinetics of Atorvastatin Tablets in Healthy Volunteers (HVs)Status: Completed, Estimated PCD: 2022-08-23
Clinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Intravenous Doses of BI 3032950 in Healthy Male and Female Subjects (Single-blind, Randomised Within Dose Groups, Placebo-controlled Parallel-group Design)Status: Recruiting, Estimated PCD: 2024-09-13
Clinical trial
A Safety, Tolerability, and Pharmacokinetic Study of 1- and 2-mL Injections of LY3074828 Solution Using Investigational Pre-filled Syringes and Investigational Autoinjectors in Healthy SubjectsStatus: Completed, Estimated PCD: 2018-08-13
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MAD_ND003Clinical trial
A Phase 1 Clinical Study to Evaluate the Pharmacokinetic Comparability, Safety, Tolerability, and Immunogenicity of Felzartamab for Injection in Healthy Male Adult Subjects in China (Randomized, Double-blind, Crossover Design)Status: Recruiting, Estimated PCD: 2024-12-31
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A Randomized, Open-Label, Six-Sequence, Three-Period Crossover Study to Demonstrate the Bioequivalence of Single Oral Administration of K-001 Relative to Single Oral Coadministration of Separate Tablets of K-877-ER Plus CSG452 in Healthy Adult Volunteers, and to Characterize the Food Effect on the Pharmacokinetics of K-001Status: Completed, Estimated PCD: 2023-04-01
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K-877-ERClinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Intravenous Doses of BI 765423 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Recruiting, Estimated PCD: 2025-04-11
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JNJ-69095897Clinical trial
A Phase 1, Open-Label Study to Investigate Drug-Drug Interaction (DDI) Potential of Nipocalimab With Coadministration of Etanercept or Hydroxychloroquine in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-05-27
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A Randomized, Double-Blind, Placebo-Controlled Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenously Administered PRT064445, a Factor Xa (fXa) Inhibitor AntidoteStatus: Completed, Estimated PCD: 2012-09-01
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RAY1225Product
HydroxychloroquineClinical trial
A Phase I, Placebo-controlled, Double-blind, First-in-human Study to Investigate Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GS-248 Solution in Healthy Subjects and Patients With Systemic Sclerosis (SSc)Status: Completed, Estimated PCD: 2019-12-20
Product
GS-248Clinical trial
A Multi-Center, Open-Label, Single-Dose Study to Evaluate the Pharmacokinetics of MCI-186 in Subjects With Mild or Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic FunctionStatus: Completed, Estimated PCD: 2018-07-20
Clinical trial
A Phase 1, Open-Label, Multiple-Dose, Parallel Study to Determine the Effect of Renal Impairment on the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of ALXN2050 in Adult ParticipantsStatus: Completed, Estimated PCD: 2022-02-18
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A Randomized, Open-label, 2-Way-Crossover Study Assessing the Bioequivalence Between Single Doses of 500 mg Glucophage® XR RM Tablets (Merck/China Jiangsu-Manufactured) and 500 mg Glucophage® XR RM Tablets (Merck/Germany Darmstadt-Manufactured) Under Fed and Fasted State in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-01-03
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CosentyxClinical trial
A Phase 1, Randomized, Double-blinded, Vehicle-controlled, Single and Multi-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics in Healthy Volunteers of the Novel Self-Administered Intranasal CG- SpikeDown Antiviral DrugStatus: , Estimated PCD: 2023-01-01
Product
SinsunatovirProduct
Ad26.RSV.preF + RSV preFProduct
NXC736Product
RamucirumabClinical trial
Comparative Randomized, Single Dose, Two-way Crossover Bioequivalence Study to Determine the Bioequivalence Aripiprazole From Apipe 10 mg Orally Disintegrating Tablets (Man. by: P&C Labs (Pellets & CR Products), Egypt) Versus Abilify 10 mg Orodispersible Tablets (Otsuka Pharmaceutical Netherlands B.V., Netherlands)Status: Completed, Estimated PCD: 2022-11-07
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A Single-dose, Open-label, Single Arm Study to Investigate PK of Xevinapant (Debio 1143) and Its Metabolite, D-1143-MET1 in Healthy East Asian ParticipantsStatus: Completed, Estimated PCD: 2023-04-21
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BI 690517Product
IA-14069Product
Metformin HCl XRClinical trial
An Open-label, Active-controlled, Randomized, Three-cycle, Crossover Trial to Evaluate the Pharmacokinetics and Pharmacodynamics of Single-Dose THDB0206 Injection in Healthy Chinese SubjectsStatus: Completed, Estimated PCD: 2022-06-06
Clinical trial
A Double-Blind, Randomized, Placebo-Controlled, Phase I Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Escalating Intravenous Doses of CM-101 in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2018-02-18
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Choriogonadotropin AlphaClinical trial
A Randomized, Open-label, Crossover Phase 1 Clinical Trial to Evaluate Food-Effects on Pharmacokinetics and Pharmacodynamics of Oral Single Dose of JP-1366 Tablet in Healthy VolunteersStatus: Not yet recruiting, Estimated PCD: 2023-04-01
Product
ASC11Clinical trial
The Effect of Repeat Dosing of Imlunestrant on CYP3A Activity in Healthy Women of Non-childbearing PotentialStatus: Completed, Estimated PCD: 2022-11-30
Product
VigilProduct
[oxoisoindolin-14C]ARV-471Product
EsomeprazoleProduct
Jiashen TabletsProduct
CyclosporineClinical trial
Comparative Randomized, Single Dose, Two-way Crossover Bioequivalence Study to Determine the Bioequivalence of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg Tablets (Teva GmbH, Germany)Status: Completed, Estimated PCD: 2022-11-22
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DA-5216Clinical trial
Relative Bioavailability of 100 mg Nintedanib (Ofev®) Given as Four Capsules of 25 mg Compared to One Capsule of 100 mg Following Oral Administration in Healthy Male Subjects (an Open-label, Randomised, Single-dose, Two-period, Two-sequence Crossover Study)Status: Completed, Estimated PCD: 2021-08-30
Product
Lenoxin®Clinical trial
A Phase 1, Single and Multiple Ascending Dose Study of NEU-723 Administered Orally to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics in Healthy SubjectsStatus: Terminated, Estimated PCD: 2023-06-30
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GFH312Clinical trial
A Phase 1, Open-label, Randomized, 2-Part, 2-Way Crossover Study in Healthy Adult Participants to Assess the Relative Bioavailability of Tablet Formulations of Lazertinib (JNJ-73841937)Status: Completed, Estimated PCD: 2023-09-01
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PF-06480605Clinical trial
An Open-label Phase I Trial to Assess Pharmacokinetics and Safety of Single Subcutaneous Doses and Single Intravenous Doses of BI 655130 in Healthy Chinese Male and Female Subjects (Single Doses, Open-label Study in Parallel-group Design).Status: Completed, Estimated PCD: 2021-04-07
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Pharmacokinetic Study of Cefazolin 3 g/150 mL in Subjects Weighing Greater Than or Equal to 120 kg Versus Cefazolin 2 g/100 mL in Subjects Weighing Less Than 120 kgStatus: Completed, Estimated PCD: 2022-08-30
Product
ATR-002Product
SpesolimapProduct
NTP42:KVA4Product
SADClinical trial
A Phase I, Single-Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LOXO-305 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2020-12-01
Clinical trial
Phase 1, Open-label, 3-Parts Study With Crossover Design in Each Part to Investigate the Bioequivalence of the Tablet Formulation of TF3 Compared to TF2 (Part A), and to Investigate the Influence of Food on the PK of Each TF2 (Part B) and TF3 (Part C) of Tepotinib in Healthy SubjectsStatus: Completed, Estimated PCD: 2019-01-25
Clinical trial
A Randomized, Double Blind, Three-arm, Parallel Group, Single Dose Comparative PK, PD, Safety and Immunogenicity Study Comparing ADL-018 With US-licensed XOLAIR in Healthy Adult SubjectsStatus: Recruiting, Estimated PCD: 2023-07-30
Clinical trial
A Phase 1 Study to Investigate the Effect of Cholestyramine on the Pharmacokinetics of LOXO-783 in Healthy AdultsStatus: Completed, Estimated PCD: 2023-07-09
Clinical trial
A Phase 1 Randomized, Placebo-Controlled Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HZN-457 in Healthy VolunteersStatus: Completed, Estimated PCD: 2023-08-09
Clinical trial
An Open-Label Study in Healthy Participants to Evaluate the Effect of LY3556050 on Metformin PharmacokineticsStatus: Completed, Estimated PCD: 2022-12-27
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A Single-center, Open-label, Fixed-sequence, Study Evaluating the Two-way Drug-drug Interaction Between JNJ-70033093 and Digoxin in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-06-09
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A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ANX1502 in Normal Healthy VolunteerStatus: Recruiting, Estimated PCD: 2023-06-30
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Phase I Study to Evaluate the Safety and Pharmacokinetics of JP-1366 in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2022-10-09
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A Phase 1, First-in-human, Randomized, Double-blind, Placebo Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DWP213388 After SAD and MAD in Healthy Adult SubjectsStatus: Not yet recruiting, Estimated PCD: 2024-02-20
Product
Ad26.ZEBOV-Batch #2Product
Ad26.ZEBOV-Batch #3Clinical trial
A Randomized, Open-label, 2-way-crossover Study Assessing the Bioequivalence Between Single Doses of 5 mg Concor® Tablets (Manufactured by Merck/China Nantong) and 5 mg Concor® Tablets (Manufactured by Merck/Germany Darmstadt) in Chinese Healthy Participants Under Fed or Fasted ConditionsStatus: Completed, Estimated PCD: 2023-06-18
Clinical trial
A Phase 1, Single-Center, Randomized, 3-Period Crossover Study in Healthy Volunteers to Evaluate the Absorption of WTX101 After Single Dose Administration of an Enteric Coated Formulation With and Without Food and a Non-Coated Formulation Coadministered With a Proton Pump Inhibitor Without FoodStatus: Completed, Estimated PCD: 2014-05-29
Product
MetaglipClinical trial
Cannabidiol Effects on Cardiovascular System and Exercise ResponsesStatus: Withdrawn, Estimated PCD: 2024-12-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Ciprofloxacin Extended-Release Tablets (1000 mg; Mylan) and Cipro® XR Tablets (1000 mg; Bayer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-10-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Metoprolol Tartrate/Hydrochlorothiazide Tablets (100/50 mg; Mylan) and Lopressor HCT® Tablets (100/50 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-02-01
Product
Lopressor HCTClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Escitalopram Oxalate Tablets (20 mg; Mylan) to Lexapro® Tablets (20 mg; Forest) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-10-01
Clinical trial
Single-Dose Fasting Bioequivalence Study of Paroxetine Hydrochloride Tablets (40 mg; Mylan) and Paxil® Tablets (40 mg; GSK) in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2006-12-01
Product
Paroxetine hydrochlorideProduct
PaxilClinical trial
the BIS Index Response is Poorly Described by Propofol Effect Site Eleveld's Model After Applying a PerturbationStatus: Recruiting, Estimated PCD: 2023-09-15
Product
Fixed Propofol InfusionClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Fexofenadine Tablets (180 mg; Mylan) and Allegra® Tablets (180 mg; Aventis) in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2003-11-01
Product
SertralineProduct
IntranasalProduct
PerampanelClinical trial
Single-Dose Food In Vivo Bioequivalence Study Metformin Hydrochloride ER Tablets (750 mg; Mylan) and Glucophage XR (750 mg; Bristol-Myers Squibb) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-12-01
Clinical trial
Single-Dose Fasting Bioequivalence Study of Verapamil HCl Extended-Release Capsules (300 mg; Mylan) to Verelan® PM Extended-Release Capsules (300 mg; Schwarz) in Healthy Volunteers Dosed in the EveningStatus: Completed, Estimated PCD: 2006-03-01
Clinical trial
The Role of Oxytocin in the Perception of Infant FacesStatus: Completed, Estimated PCD: 2015-12-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Mylan Nitrofurantoin Monohydrate/Macrocrystals Capsules (100 mg; Mylan) and Macrobid® Capsules (100 mg; Procter & Gamble) in Healthy Volunteers.Status: , Estimated PCD: 2002-08-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Alprazolam Extended-Release Tablets (3 mg; Mylan) to Xanax XR® Tablets (3 mg; Pharmacia & Upjohn) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-08-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Rabeprazole Sodium Delayed-Release Tablets (20 mg; Mylan) to Aciphex® Delayed-Release Tablets (20 mg; Eisia) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-06-01
Product
CD101Product
EscitalopramProduct
ApixabanDrug
MetforminProduct
KRGClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Sertraline Hydrochloride Tablets (100 mg; Mylan) and Zoloft® Tablets (100 mg; Pfizer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Lorazepam Tablets (2 mg; Mylan) and Ativan Tablets (2 mg; Wyeth) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-12-01
Product
AtivanClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Mercaptopurine (50 mg; Mylan) and Purinethol® Tablets (50 mg; Gate) in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2003-12-01
Product
Propranolol HydrochlorideClinical trial
A Randomized, Double-Blind, 3-arm, Parallel Group, Placebo- and Positive-controlled Study to Investigate the Effects of Setmelanotide on QTc Interval in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-04-07
Product
Oral PlaceboProduct
SC PlaceboProduct
Artificial tearClinical trial
A Randomized, Double-Blind, Placebo-Controlled, Phase 1, Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Food Effect of THB335 in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2025-03-15
Clinical trial
Bioequivalence of Two Sifrol® Tablets Following Oral Administration in Healthy Subjects (an Open-label, Randomised, Single-dose, Two-way Crossover Trial)Status: Not yet recruiting, Estimated PCD: 2024-07-30
Product
PramipexoleClinical trial
A Study to Assess the Pharmacokinetics, Tolerability and Safety of the Co-administration of Sancuso® (Transdermal Granisetron) and Intravenous Granisetron in Healthy SubjectsStatus: Completed, Estimated PCD: 2009-05-01
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BuphenylClinical trial
Efficacy of Cetylpyridinium Chloride and Zinc Mouthwash in Reducing the Occurrence of Symptoms Associated With the Flu and Cold Season - a Randomized Clinical TrialStatus: Completed, Estimated PCD: 2022-10-06
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TralokinumabProduct
Camlipixant + RabeprazoleClinical trial
An Open-label, Parallel-group Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Cenerimod After Single-dose Administration in Subjects With Severe Renal Impairment and Control SubjectsStatus: Completed, Estimated PCD: 2023-07-27
Clinical trial
Relative Bioavailability of BI 894416 as Tablet Formulation Following a High-fat, High-calorie Breakfast Compared to Administration in the Fasting State in Healthy Male Subjects (an Open-label, Randomised, Single-dose, Two-period, Two-sequence Crossover Study)Status: Completed, Estimated PCD: 2019-04-24
Product
DPA-714Product
OPT101Product
Placebo salineProduct
H107eDrug
BCGClinical trial
A Multicenter, Randomized, Double-blind, Placebo-controlled Phase IIa Clinical Trial to Evaluate the Efficacy and Safety of Oral Local Use of GB001 Recombinant Peptide Spray for the Treatment of Mild Recurrent Aphthous UlcerStatus: Active (not recruiting), Estimated PCD: 2023-12-06
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Measurement of Insulin Levels in the Cerebrospinal Fluid (CSF) of Healthy Adults After a Single Intranasal Dose - Middle AgeStatus: Not yet recruiting, Estimated PCD: 2026-02-28
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Investigational Study of the Effect of Clinical Procedures on Drug Delivery of the Fentanyl Transdermal System (25 µg/hr; Mylan) and Duragesic® (25 µg/hr; Janssen) in Healthy VolunteersStatus: , Estimated PCD: 2006-10-01
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A Double-blind, Randomized, Placebo Controlled, Combined Single and Multiple Ascending Dose, Phase 1 Study to Investigate the Safety, Tolerability and Pharmacokinetic and Pharmacodynamics of PG-102(MG12) in Healthy VolunteersStatus: Recruiting, Estimated PCD: 2024-06-26
Clinical trial
Multi-organ Transit Time Acquisition Using Contrast UltrasoundStatus: Active (not recruiting), Estimated PCD: 2023-06-16
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Safety, Tolerability and Pharmacokinetics of Single Subcutaneous Doses of BI 3034701 in Healthy Male Volunteers (Part A) and of Multiple Rising Subcutaneous Doses in Otherwise Healthy Male and Female Volunteers With Obesity/Overweight (Part B)Status: Recruiting, Estimated PCD: 2025-10-13
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Artemether-lumefantrineProduct
AmodiaquineProduct
AquaminProduct
Intranasal oxytocinClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Ondansetron Orally Disintegrating Tablets (8 mg; Mylan) to Zofran ODT® Tablets (8 mg; GlaxoSmithKline) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-07-01
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Regimen 2Product
Regimen 3Product
Genomic SequencingClinical trial
Effects of Changing Intestinal Transit Time on Gut Microbial Composition and Metabolism During a Dietary Intervention With Low and High Fiber.Status: Recruiting, Estimated PCD: 2024-12-01
Product
Diet + LaxativeProduct
Doxycycline MonohydrateClinical trial
A Single Ascending and Multiple Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3873862 in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2025-06-01
Product
AmoxicillinProduct
VoSpire ERClinical trial
A Phase 1, Open-label, Positron Emission Tomography Study in Healthy Subjects to Determine the Relationship Between Plasma Concentration and Target Occupancy of ASN51 Following Repeated Oral Doses.Status: Completed, Estimated PCD: 2023-04-04
Clinical trial
A PHASE 1, RANDOMIZED, OPEN-LABEL, SINGLE-DOSE, PARALLEL-GROUP STUDY TO COMPARE THE PHARMACOKINETICS AND RELATIVE BIOAVAILABILITY OF MEDROXYPROGESTERONE ACETATE IN HEALTHY FEMALE PARTICIPANTS FOLLOWING SUBCUTANEOUS INJECTION OF SAYANA PRESS IN THE UPPER ARM RELATIVE TO ANTERIOR THIGH AND ABDOMENStatus: Recruiting, Estimated PCD: 2025-03-05
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Sayana PressProduct
Glipizide + Metformin HClClinical trial
Filgrastim-Mobilized Peripheral Blood Stem Cells for Allogeneic Transplantation With Unrelated DonorsStatus: Recruiting, Estimated PCD: 2030-01-01
Clinical trial
Effect of Ghrelin on Sympathetic Nervous System and Stress ReactivityStatus: Completed, Estimated PCD: 2010-05-01
Product
ghrelinProduct
PF-07940367Clinical trial
Mechanisms of Ozone-Induced Alterations in Efferocytosis and PhagocytosisStatus: Completed, Estimated PCD: 2023-07-26
Product
ZithromaxClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Paroxetine Hydrochloride Controlled-Release Tablets (25 mg; Mylan) to Paxil CR™ Tablets (25 mg; GlaxoSmithKline) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-04-01
Product
BaclofenProduct
Escitalopram OxalateClinical trial
Single-Dose Food in Vivo Bioequivalence Study of Benazepril HCl and Hydrochlorothiazide Tablets (20 mg/25 mg; Mylan) to Lotensin HCT® Tablets (20 mg/25 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Product
AccureticClinical trial
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid InfusionStatus: Recruiting, Estimated PCD: 2025-06-30
Clinical trial
Glutamatergic Mechanisms of Psychosis and Target Engagement (SA1)Status: Active (not recruiting), Estimated PCD: 2024-12-01
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NabiloneClinical trial
Activating Neuroplasticity to ENHANCE the Perception Box Expanding Effects of PsilocybinStatus: Not yet recruiting, Estimated PCD: 2027-07-01
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A Double Blind, Randomized Study Assessing the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of IBI355 in Healthy VoluteersStatus: Not yet recruiting, Estimated PCD: 2025-02-13
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Comparative Acute Effects of LSD, Psilocybin and Mescaline in a Random-Order Placebo-Controlled Cross-Over Study in Healthy SubjectsStatus: Completed, Estimated PCD: 2022-09-02
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FinasterideClinical trial
Single-Dose Food In Vivo Bioequivalence Study Metformin Hydrochloride ER Tablets (500 mg; Mylan) and Glucophage® XR (500 mg; Bristol-Myers Squibb) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-05-01
Product
CoregProduct
CetirizineProduct
Nitrofurantoin MacrocrystalsClinical trial
Investigation of the Pharmacokinetic Profile of CBDStatus: Active (not recruiting), Estimated PCD: 2023-02-14
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Modafinil Tablets (200 mg; Mylan) to Provigil® Tablets (200 mg; Cephalon) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-10-01
Product
ModafinilProduct
Carvedilol TabletsClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Ondansetron Orally Disintegrating Tablets (8 mg; Mylan) to Zofran ODT® Tablets (8 mg; GlaxoSmithKline) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-07-01
Product
Zofran ODT TabletsClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Anagrelide Hydrochloride Capsules (1 mg; Mylan) to Agrylin® Capsules (1 mg; Shire US) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-01-01
Clinical trial
A Single-Blind, Randomized, Parallel Trial to Define the ECG Effects of Sancuso® (Granisetron Transdermal System) Compared to Placebo and Moxifloxacin in Healthy Men and WomenStatus: Completed, Estimated PCD: 2009-08-01
Clinical trial
Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and AscentStatus: Recruiting, Estimated PCD: 2025-09-01
Product
PotassiumProduct
Tachipirina 120 mg/5 mLProduct
PfSPZ ChallengeClinical trial
A Phase 1, First-in-human, Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VG-3927 in Healthy AdultsStatus: , Estimated PCD: 2024-12-31
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Bowel Prep CombinationProduct
RProduct
CSG452Clinical trial
A Randomized, Open-label, Parallel Design Clinical Trial to Evaluate the Safety/Tolerability and Pharmacokinetic of DWJ211 in Healthy VolunteersStatus: Completed, Estimated PCD: 2020-04-21
Clinical trial
Safety, Tolerability and Pharmacokinetics After Continuous Infusion of KAND567. A Single-centre, Placebo-controlled, Randomised, Double-blind Study in Healthy SubjectsStatus: Completed, Estimated PCD: 2020-04-27
Clinical trial
Open, Randomized, 2-period, 2-sequence, Cross-over Relative Bioavailability Study to Investigate the Pharmacokinetics and to Assess the Bioequivalence of a Rivastigmine Test Patch Formulation 13.3 mg/24 h (Twice-weekly Patch) Compared to the Reference Exelon® 13.3 mg/24 h (Once-daily Patch) Applied for 11 DaysStatus: Completed, Estimated PCD: 2023-07-02
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A Randomized, Double-blind, Placebo-controlled Study of the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Oral Doses of CFTX-1554 in Healthy Subjects, With Comparison of Intake of CFTX-1554 as Liquid Formulation and as Capsule, and After a High-fat Breakfast Versus FastedStatus: Completed, Estimated PCD: 2023-02-10
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A Phase 1, Randomized, Double-Blind, Dose Escalation Study to Evaluate the Safety and Pharmacokinetics of a Single IM Dose of G03-52-01 vs Placebo in Adult SubjectsStatus: Active (not recruiting), Estimated PCD: 2022-08-20
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611Product
BI 764122Product
DA-1229Clinical trial
An Open-label, Single-dose, Randomized, 4-period, 2-sequence, Fully Replicated Crossover, Single-center Phase I Study to Assess Bioequivalence in Healthy Participants Between Euthyrox® Tablets Manufactured at Merck Nantong Versus Euthyrox® Tablets Manufactured at Merck Darmstadt Administered Orally as 12 Tablets of 50 μgStatus: Completed, Estimated PCD: 2022-10-18
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[¹⁴C]-LY3337641Product
XW10172Clinical trial
A Study to Investigate the Safety and Tolerability of a Wearable On-body Delivery System, and Exploratory Assessment of Participant Response With an Autoinjector, Following Subcutaneous Injections of Placebo in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-07-22
Clinical trial
A Phase 1/2a Trial to Evaluate the Safety/Tolerability and Immunogenicity of Homologous Ad26 Mosaic Vector Regimens or Ad26 Mosaic and MVA Mosaic Heterologous Vector Regimens, With High-Dose, Low-Dose or no Clade C gp140 Protein Plus Adjuvant for HIV PreventionStatus: Completed, Estimated PCD: 2017-08-29
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Humalog®Product
LY3537021Product
NVP-2002-R1+NVP-2002-R2Product
NVP-2002Product
EI-001Clinical trial
A Phase I, Single-site, Open-label, Partially Randomized Study to Evaluate the Relative Bioavailability and Pharmacokinetics of Evobrutinib Following Administration of Different Formulations in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-02-14
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casirivimab+imdevimabClinical trial
Single-center, Randomized, Double-blind, Placebo-controlled, Ascending-Dose Study to Evaluate the Safety and Pharmacokinetics of Recombinant Human Plasma Gelsolin (Rhu-pGSN) After Intravenous Administration to Healthy VolunteersStatus: Completed, Estimated PCD: 2023-05-24
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REGN7999Product
VapendavirProduct
Tenofovir AlafenamideProduct
JNJ-42847922Product
SeltorexantClinical trial
A Phase 1, Open-label, Fixed-sequence Study to Estimate the Effects of Multiple-dose Administration of Itraconazole on the Pharmacokinetics of SHR8554 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-01-21
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CelecoxibClinical trial
A Randomised, Double-blind, Three-arm, Parallel Group, Single-dose Study to Compare the Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of Denosumab (SB16, EU Sourced Prolia®, and US Sourced Prolia®) in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-11-09
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PRS-220Clinical trial
The Effect of Potent Inhibitors of Drug Transporters (Verapamil, Rifampin, Cimetidine, Probenecid) on Pharmacokinetics of a Transporter Probe Drug Cocktail Consisting of Digoxin, Furosemide, Metformin and Rosuvastatin (an Open-label, Randomised, Crossover Trial in Three Parts)Status: Completed, Estimated PCD: 2018-05-02
Clinical trial
A Randomized, Double-Blind, Placebo-Controlled, Two-Part Single Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of REGN5381 (an NPR1 Agonist) in HumansStatus: Completed, Estimated PCD: 2022-12-14
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ProbenecidProduct
RelacorilantProduct
TrichomylinClinical trial
Elucidating Mechanisms That Underlie Symptomatology of Functional Dyspepsia Using Novel Imaging Technique of SPECT/CT, MRI, High-Resolution Manometry and Biomarkers; and the Therapeutic Validation of Elucidated Mechanisms Using Neuromodulator CompoundsStatus: Recruiting, Estimated PCD: 2024-12-31
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MirtazapineClinical trial
Brain Morphological Changes Accompanied by Effective Biologic Treatments for Psoriasis and Their Associations With the Improvement of Well-being, Itch, and PainStatus: Recruiting, Estimated PCD: 2024-08-31
Drug
CelecoxibProduct
NaproxenClinical trial
Effects of MDMA-like Substances in Healthy SubjectsStatus: Active (not recruiting), Estimated PCD: 2024-05-31
Product
TerazosinClinical trial
Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - SufentanilStatus: Active (not recruiting), Estimated PCD: 2024-08-31
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Lanthanum CarbonateClinical trial
Measurement of Insulin Levels in Cerebral Spinal Fluid (CSF) of Healthy Adults After a Single Intranasal DoseStatus: Recruiting, Estimated PCD: 2024-08-01
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Single-Dose Fasting In Vivo Bioequivalence Study of Metolazone Tablets (10 mg; Mylan) and Zaroloxyn® Tablets (10 mg; Celltech) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-02-01
Product
DexrazoxaneClinical trial
Phase 1 Study Evaluating the Safety of [11C]MeDAS Myelin-Targeting PET Agent in HumansStatus: Not yet recruiting, Estimated PCD: 2025-12-01
Clinical trial
A PHASE 1 SINGLE INTRANASAL DOSE, OPEN-LABEL PHARMACOKINETIC STUDY OF ZAVEGEPANT IN HEALTHY LACTATING WOMENStatus: Not yet recruiting, Estimated PCD: 2025-02-10
Clinical trial
the Association of Psychological Distress in Patients With Advanced Lung Cancer Treated With Immunotherapy or Targeted TherapyStatus: Recruiting, Estimated PCD: 2027-12-31
Drug
immunotherapyProduct
DexmedetomidineProduct
NorepinephrineProduct
MDMAProduct
MadoparProduct
propranololClinical trial
A Phase I, First-in-human, Randomised, Double-blind, Placebo-controlled, Single Ascending Oral Dose, Safety, Tolerability and Pharmacokinetic Study to Investigate the Effects of OCT461201 in Healthy VolunteersStatus: Completed, Estimated PCD: 2023-09-25
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BilastineProduct
AVT16Clinical trial
In Vivo Study of THC-induced Immune-genome Changes at Single Cell Solution in HIV-infected HumansStatus: Recruiting, Estimated PCD: 2025-06-30
Clinical trial
A Single Center, Randomized, Double-blind, Placebo-controlled Phase I Clinical Trial of a Novel Recombinant Humanized Anti Interleukin-6 Receptor Monoclonal Antibody in Healthy SubjectsStatus: Completed, Estimated PCD: 2020-01-06
Clinical trial
Testing the Interactive Effects of Delta-9-Tetrahydrocannabinol and PregnenoloneStatus: Completed, Estimated PCD: 2019-06-24
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Metolazone Tablets (2.5 mg; Mylan) and Zaroloxyn® Tablets (2.5 mg; Celltech) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
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Lamictal TabletsClinical trial
Epigenetic Mechanism Reprogramming Mucosal Anti-viral Immunity in Allergic Asthma VIRAL MUCOSAL REPROGRAMMINGStatus: Recruiting, Estimated PCD: 2027-05-01
Product
EpaminuradProduct
LSD + OlanzapineProduct
LSD + LorazepamClinical trial
Effects of Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier FunctionStatus: Recruiting, Estimated PCD: 2024-11-30
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Loxapine Succinate Capsules (25 mg; Mylan) and Loxitane® Capsules (25 mg; Watson) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-02-01
Product
LoxitaneClinical trial
Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of GB002 Recombinant Polypeptide Inhalation Solution in a Randomized, Double-blind, Placebo-controlled, Dose-increasing Single and Multiple Administration in Chinese Healthy Adult Subjects.Status: Active (not recruiting), Estimated PCD: 2024-05-30
Product
SPY001-001Product
Yohimbine + HydrocortisoneClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Ondansetron Tablets (24 mg; Mylan) and Zofran® Tablets (24 mg; GSK) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-07-01
Clinical trial
Open-Label Study to Evaluate Pharmacokinetic Properties and Mosquito-Lethal Effect of Ivermectin Metabolites in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-04-05
Product
LixisenatideClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Paroxetine Hydrochloride Controlled-Release Tablets (25 mg; Mylan) to Paxil CR™ Tablets (25 mg; GlaxoSmithKline) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-05-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Lamotrigine Tablets (25 mg; Mylan) to Lamictal® Tablets (25 mg; GSK) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-08-01
Product
LamictalClinical trial
Cardiovascular Consequences of Prolonged Inhaled Short-acting Beta-agonist Use in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2024-08-01
Product
SalbutamolClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Valacyclovir Hydrochloride Tablets (1000 mg; Mylan) to Valtrex® Tablets (1000 mg; GlaxoSmithKline) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-05-01
Product
DF-003Product
AlprazolamProduct
JNJ-72537634Product
Cetirizine HClClinical trial
A Phase 1 Study Comparing the Pharmacokinetics and Safety of Intravenous and Oral PsilocybinStatus: Withdrawn, Estimated PCD: 2024-03-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Quinapril HCl and Hydrochlorothiazide Tablets (20 mg/25 mg; Mylan) to Accuretic™ Tablets (20 mg/25 mg; Parke-Davis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-09-01
Clinical trial
A PHASE 1, OPEN-LABEL, RANDOMIZED, SINGLE-DOSE, 2-WAY CROSSOVER, PIVOTAL BIOEQUIVALENCE STUDY COMPARING 50-MG CHEWABLE DILANTIN® INFATABS® MANUFACTURED AT VEGA BAJA (PUERTO RICO) AND ASCOLI (ITALY) IN HEALTHY ADULT PARTICIPANTS UNDER FASTING CONDITIONSStatus: Not yet recruiting, Estimated PCD: 2024-11-08
Clinical trial
A Phase I Clinical Trial in Healthy and Overweight/Obese Subjects to Investigate the Safety, Tolerability and Pharmacokinetics of Mulberry Twig AlkaloidsStatus: Recruiting, Estimated PCD: 2024-10-19
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PlaceboClinical trial
An Open-label, Nonrandomized, Single-dose, Parallel-group, Safety, Tolerance, and Pharmacokinetic Study of LOXO-305 Administered to Fasted Hepatically Impaired Male and Female Subjects and Fasted Matched-control Healthy SubjectsStatus: Completed, Estimated PCD: 2021-12-30
Product
[14C]-LY3556050Clinical trial
A Phase I Study to Assess Safety, Tolerability, Pharmacokinetics and Effect of Food on Multiple Rising Oral Doses of BI 1839100 (Single-blind, Randomised, Placebo-controlled, Parallel Group Design) and the Effect of Multiple Doses of BI 1839100 on the Single Dose Pharmacokinetics of Cytochrome P450 Substrate (Midazolam), a P Glycoprotein Substrate (Digoxin) and OATP Substrate (Rosuvastatin) Administered Orally (Open-label, Fixed-sequence) in Healthy Male SubjectsStatus: Recruiting, Estimated PCD: 2024-06-07
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BI 695501Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single and Multiple Ascending Dose Study of Subcutaneous and Intravenous ALXN1820 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-09-01
Product
midazolamClinical trial
The Effect of Multiple Oral Doses of BI 1015550 on the Pharmacokinetics of Nintedanib and Pirfenidone Administered Single Dose to Healthy Male Subjects (Open-label, Two-period, Fixed-sequence Crossover Trial)Status: Completed, Estimated PCD: 2023-12-14
Product
PirfenidoneProduct
digoxinProduct
BI 456906Product
LY3841136Product
BI 474121Product
LY3839840Clinical trial
Single- and Multiple-Ascending Dose Study to Evaluate the Safety and Pharmacokinetics of LY3839840 Following Oral Dosing in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2024-06-13
Product
MT-6548Clinical trial
Phase Ⅲ, Randomized, Double-blind, Active Controlled to Evaluate the Immunogenicity and Safety of "IL-YANG Quadrivalent Seasonal Influenza Vaccine" in Healthy Infants From 6 Months to Under 3 Years of Age(≥ 6 Months and < 3 Years)Status: Not yet recruiting, Estimated PCD: 2025-02-28
Product
Fluarix TetraProduct
BI 409306Product
PF-07038124Clinical trial
A Phase 2a, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Antiviral Activity, Safety, and Pharmacokinetics of Repeated Oral Doses of JNJ-64281802 Against Dengue Serotype 1 Infection in a Dengue Human Challenge Model in Healthy Adult ParticipantsStatus: , Estimated PCD: 2024-01-31
Product
JNJ-64281802Clinical trial
A Phase I, Randomized, Partial Double-blind, Single Dose, 3 Way Cross Over Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol for BGF MDI HFO Compared With BGF MDI HFA Using an AeroChamber Plus Flow Vu Spacer and to Compare the Lung Exposure of BGF MDI HFO With a Spacer to BGF MDI HFO Without a SpacerStatus: Not yet recruiting, Estimated PCD: 2024-10-28
Product
BupivacaineProduct
[14C]HSK31679Product
BardoxoloneClinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Different Titration Schedules of Subcutaneous Doses of BI 1820237 Alone or Together With Either Semaglutide or BI 456906 in Otherwise Healthy Male and Female Individuals With Obesity/Overweight (Multiple Dose, Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Active (not recruiting), Estimated PCD: 2024-07-31
Product
CM313Product
Tetramethylpyrazine nitroneClinical trial
A Phase 1, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Single-Ascending Dose Study of LY3844583 in Healthy Participants, and Multiple-Dose Study of LY3844583 in Healthy Participants and Patients With Atopic DermatitisStatus: Completed, Estimated PCD: 2024-01-20
Clinical trial
A RANDOMIZED, DOUBLE-BLIND, PLACEBO CONTROLLED EVALUATION OF SINGLE DOSES OF PF-07209326 IN HEALTHY PARTICIPANTS (SAFETY, TOLERABILITY, AND PHARMACOKINETICS [PK]) FOLLOWED BY AN OPEN LABEL, REPEAT DOSE EVALUATION IN SICKLE CELL DISEASE PARTICIPANTS (SAFETY, TOLERABILITY, PK AND EFFICACY)Status: Completed, Estimated PCD: 2023-07-07
Clinical trial
A Randomized, Single-blind, Placebo-controlled, Sequential Parallel-Group and Multiple Ascending Dose (MAD) Study to Evaluate the Safety, Tolerability and Pharmacokinetics of KBP-7072 in Healthy SubjectsStatus: Completed, Estimated PCD: 2015-12-01
Clinical trial
A Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of RTA 1701 in Healthy AdultsStatus: Completed, Estimated PCD: 2019-06-28
Product
PF-07264660Product
RTA 901Clinical trial
A Phase 1, Single-Centre, Open-Label, Two-Part, Sequential Cross-Over Study Designed to Assess the Pharmacokinetic Profile of BLU-5937 Following Administration of Extended Release Formulation Prototypes and an Immediate Release Reference Formulation in Healthy Male and Female SubjectsStatus: Recruiting, Estimated PCD: 2024-06-28
Product
Matching placeboProduct
CKR-051Clinical trial
A Randomized, Single-blind, Placebo-controlled, Single/Multiple Dose, Dose Escalation, Phase 1 Clinical Trial to Evaluate Safety, Tolerability and Pharmacokinetic Characteristics of CKR-051 After Transdermal Administration in Healthy Male Subjects.Status: Completed, Estimated PCD: 2024-01-08
Clinical trial
A Phase 1 Study to Evaluate the Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole, and Carbamazepine in Healthy Adult ParticipantsStatus: Recruiting, Estimated PCD: 2024-05-06
Clinical trial
An Open-Label, Parallel-Group, Single Ascending Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability and Pharmacokinetics of KBP-5074 Following Oral Administration and With a Food Effect PanelStatus: Completed, Estimated PCD: 2015-01-01
Clinical trial
A Single Dose Study to Assess the Pharmacokinetics of 2 Formulations of LY3819469 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-11-07
Clinical trial
A First-in-Human, Phase I, Double-blind, Placebo-controlled, Single and Multiple Ascending Oral Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of KRP-A218 in Healthy Subjects, Including Food-Effect and Drug-drug Interaction With ItraconazoleStatus: Completed, Estimated PCD: 2022-04-21
Clinical trial
A Randomized, Open-label, Multiple-dose, Crossover Phase I Clinical Trial to Compare the Safety, Pharmacokinetics and Pharmacodynamics After Oral Administration of JW0302 to C2206 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2023-06-09
Product
LY3938577Product
RLD2205Product
DulaglutideProduct
RTA 408 LotionClinical trial
A PHASE 1, RANDOMIZED, OPEN-LABEL, 2-PART CROSSOVER STUDY TO ASSESS THE RELATIVE BIOAVAILABILITY OF SISUNATOVIR FOLLOWING SINGLE ORAL DOSE OF DIFFERENT FORMULATIONS UNDER FED AND FASTED CONDITIONS IN HEALTHY ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2024-02-26
Clinical trial
A Randomized, Single-dose, Open-label, Two-way Crossover Pivotal Study to Assess the Bioequivalence Between Albuterol Sulfate Inhalation Aerosol 108mcg Per Actuation (MDI, eq. to Albuterol 90mcg/Puff) and Proair HFA (Albuterol Sulfate) Inhalation Aerosol 90mcg Per Actuation (MDI, eq. to Albuterol 90mcg/Puff) in Healthy Volunteers Under Fasting ConditionsStatus: Completed, Estimated PCD: 2022-04-25
Product
EncorafenibProduct
RabeprazoleProduct
ALXN1210Product
HSK31679Product
LY3372993Clinical trial
A Phase 1, Randomized, Double-blind, Placebo-controlled, Single Ascending Dose Study of Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Subcutaneous ALXN2030 in Healthy ParticipantsStatus: Recruiting, Estimated PCD: 2025-02-04
Product
OritavancinClinical trial
A Randomized, Double-Blind, Single Center Cohort Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a New Formulation of a Single 1200MG IV Dose of Oritavancin in Healthy VolunteersStatus: Completed, Estimated PCD: 2016-04-01
Clinical trial
A Double-Blind Randomized Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple 1200 mg Dose Intravenous Oritavancin Infusions in Healthy SubjectsStatus: Completed, Estimated PCD: 2015-10-01
Product
BI 1291583Product
RavulizumabClinical trial
A Phase I, Single-Dose, Randomized, Partially Double-Blind, Placebo- and Positive-Controlled, 3-Way Crossover Study to Evaluate the Effect of LOXO-305 on QTc Interval in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-03-31
Clinical trial
A Phase 1, Randomized, Double-blind, Sponsor-Open, Placebo- and Positive-Controlled Crossover Study to Investigate the Effect of Multiple Doses of Sisunatovir on QTc Interval in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2023-10-30
Product
Insulin LisproClinical trial
A Phase 1, Double-Blind, Placebo-Controlled, Safety, Tolerability and Pharmacokinetics Study of PRA023 in Healthy VolunteersStatus: Completed, Estimated PCD: 2021-09-23
Product
PeresolimabClinical trial
A Phase 1, Open-label, Single-dose, Parallel-group Study to Evaluate the Plasma Pharmacokinetics and Safety of Obicetrapib in Participants With Moderate Hepatic Impairment Relative to Participants With Normal Hepatic FunctionStatus: Recruiting, Estimated PCD: 2024-05-31
Clinical trial
A Phase 1 Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-Bardoxolone Methyl Following a Single Oral Dose Administration in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2011-12-31
Product
RTA 1701Clinical trial
Single-Dose Fasting Bioequivalence Study of Verapamil HCl Extended-Release Capsules (300 mg; Mylan) to Verelan® PM Extended-Release Capsules (300 mg; Schwarz) in Healthy Volunteers Dosed in the EveningStatus: Completed, Estimated PCD: 2006-01-01
Clinical trial
A Phase 1 Study to Evaluate the Effects of Multiple Doses of Itraconazole or Carbamazepine on the Single-Dose Pharmacokinetics of LY3537982 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2023-08-28
Product
Bardoxolone MethylProduct
TachipirinaProduct
Ditropan XLProduct
Verelan PMProduct
IVX-121Clinical trial
A Phase 1 Randomized, Observer-blind, Placebo-controlled, Multi-center Trial to Evaluate the Safety and Immunogenicity of IVX-A12, a Respiratory Syncytial Virus and Human Metapneumovirus Bivalent Combination Virus-like Particle Protein Subunit Vaccine, in Healthy Adults, 60 to 75 Years of AgeStatus: Completed, Estimated PCD: 2024-01-24
Clinical trial
Single-Dose Fasting Bioequivalence Study of Nadolol/Bendroflumethiazide Tablets (80 mg/5 mg; Mylan) to Corzide® Tablets (80 mg/5 mg; King) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-08-01
Product
CorzideClinical trial
A Phase 1, Open-label, Parallel-group Study to Assess the Effect of Steady-state Carbamazepine on the Pharmacokinetics of Ponesimod in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2023-03-05
Clinical trial
A Randomized, Open Label, Single Dose, 4-period Replicate Crossover Clinical Trial to Evaluate the Pharmacokinetic Characteristics and Safety After Administration of a Fixed-dose Combination Drug of HCP2201 and Co-administration of RLD2205 and RLD2206 in Healthy Male Volunteers Under Fasting ConditionsStatus: Completed, Estimated PCD: 2023-05-14
Product
sisunatovirProduct
Lactose-free memantineProduct
MemantineClinical trial
Single-Dose In Vivo Bioequivalence and Wear Study of Fentanyl Transdermal System (25 µg/h; Mylan) and Fentanyl Transdermal System With Overlay (25 µg/h; Mylan) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-07-01
Clinical trial
A Phase 1, Double Blind, Randomized, Placebo-Controlled First in Human Study, to Assess the Safety, Tolerability and Pharmacokinetics of BAP5191 Following Topical Application of Repeat Doses in Healthy Adult ParticipantsStatus: Active (not recruiting), Estimated PCD: 2024-03-15
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repaglinideClinical trial
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Rising Doses of BI 409306 Film-coated Tablets Given Orally q.d. for 14 Days in Young and Elderly Healthy Male/Female Volunteers (Randomized, Double-blind, Placebo Controlled Within Dose Groups Phase I Study)Status: Completed, Estimated PCD: 2012-08-01
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Olmesartan MedoxomilClinical trial
Safety, Tolerability and Pharmacokinetics of Multiple Rising Oral Doses of BI 474121 in Young and Elderly Healthy Male and Female Subjects (Double-blind, Randomised, Placebo-controlled, Parallel Group Design) and Evaluation of Midazolam Interaction in Young Healthy Male and Female Subjects (Nested, Open, Fixed-sequence, Intra-individual Comparison)Status: Completed, Estimated PCD: 2021-10-07
Product
PrednisoneProduct
LY3541105Clinical trial
A Phase 1, Randomized, Placebo-Controlled, Dose-Escalation Study to Evaluate the Safety, Tolerability, and PK of LY3541105 Following Single Doses in Healthy/Overweight Participants and Multiple Doses in Overweight ParticipantsStatus: Active (not recruiting), Estimated PCD: 2024-08-01
Clinical trial
Safety, Pharmacokinetics, and Pharmacodynamics of a Single, Ascending Dose of WAL0921 in Healthy SubjectsStatus: Completed, Estimated PCD: 2024-01-09
Product
C1K 300mgProduct
ZonisamideClinical trial
A Drug-Drug Interaction Study to Assess the Effect of Carbamazepine on the Pharmacokinetics of Orforglipron in Healthy ParticipantsStatus: Not yet recruiting, Estimated PCD: 2024-07-15
Clinical trial
Pharmacokinetics, Safety, and Tolerability of BI 456906 Following Subcutaneous Injection in Male and Female Participants With Mild, Moderate and Severe Renal Impairment in Comparison to Participants With Normal Renal Function (Mono-centric, Open-label Study With Parallel Matched-pair Design)Status: Not yet recruiting, Estimated PCD: 2024-11-26
Clinical trial
Single-Dose Fed Bioequivalence Study of Olmesartan Medoxomil and Hydrochlorothiazide Tablets (40 mg/25 mg; Mylan) to Benicar HCT® Tablets (40 mg/25 mg; Sankyo) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-11-01
Product
BenicarProduct
TicagrelorClinical trial
A Phase 2B, Randomized, Double-blind, Multicenter, Placebo-controlled Study to Evaluate the Efficacy of Bentracimab (PB2452) in Reversing Ticagrelor in Subjects Aged 50 to 80 Years OldStatus: Completed, Estimated PCD: 2021-09-01
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BCD-180Clinical trial
A PHASE 1, RANDOMIZED, OPEN-LABEL, 4-PERIOD, 5-TREATMENT, 6-SEQUENCE, CROSSOVER, SINGLE-DOSE STUDY IN HEALTHY PARTICIPANTS TO INVESTIGATE THE EFFECT OF TABLET FORMULATION AND FOOD ON THE BIOAVAILABILITY OF PF-07104091Status: Completed, Estimated PCD: 2022-10-17
Clinical trial
A Phase 2a Randomized, Observer-blind, Placebo-controlled, Dosage Optimization, Multi-center Clinical Trial to Evaluate the Safety and Immunogenicity of IVX-A12, a Respiratory Syncytial Virus and Human Metapneumovirus Bivalent Combination Virus-like Particle Protein Subunit Vaccine, in Adults 60 to 85 Years of AgeStatus: Active (not recruiting), Estimated PCD: 2025-07-05
Product
LOXO-305Product
BI 765423Clinical trial
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Intravenous Doses of BI 765423 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2024-03-19
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BI 3032950Product
BI 765250Clinical trial
A Phase 1, Single-Dose Study to Assess the Relative Bioavailability, Absolute Bioavailability, and Tolerability of LY3074828 Formulations in Healthy SubjectsStatus: Completed, Estimated PCD: 2018-04-03
Clinical trial
A Phase 1, Open-Label, Single Ascending and Multiple Set Dose Study to Evaluate the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of ALXN1210 Administered Intravenously to Healthy Japanese SubjectsStatus: Completed, Estimated PCD: 2017-07-05
Product
ALXN1830Clinical trial
Pharmacokinetics of a Heptavalent Equine-derived Botulinum Antitoxin (NP-018)Status: Completed, Estimated PCD: 2006-12-01
Clinical trial
Single Ascending Dose and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetic and Food Effect of ND-003 Tablets in Healthy Adult VolunteersStatus: Not yet recruiting, Estimated PCD: 2024-12-01
Clinical trial
Safety, Tolerability, and Pharmacokinetics of Multiple Rising Oral Doses of BI 1584862 in Healthy Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Active (not recruiting), Estimated PCD: 2024-05-06
Clinical trial
A First in Human, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LC542019 in Healthy Subjects and Subjects With T2DMStatus: Completed, Estimated PCD: 2023-12-14
Clinical trial
A Randomized, Double-blind, Placebo-controlled, Sequential Parallel Group, Single Ascending Dose Study in Healthy Subjects to Evaluate the Safety, Tolerability and Pharmacokinetics of KBP-7072 Following Oral AdministrationStatus: Completed, Estimated PCD: 2015-10-01
Product
Lysergic Acid DiethylamideProduct
HCP1904-1Clinical trial
Comparative, Randomized, Single Dose, Two-way Crossover Bioequivalence Study to Determine the Bioequivalence of Metformin HCl From Gleptomet 50/1000 mg F.C.Tablets (EVA Pharma for Pharmaceuticals & Medical Appliances, Egypt) and Janumet 50/1000 mg F.C.Tablets (Merck Sharp & Dohme, The Netherlands) After a Single Oral Dose Administration of Each to Healthy Adults Under Fed Conditions.Status: Completed, Estimated PCD: 2022-12-13
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FurosemideClinical trial
A Phase 3 Open-label Randomized Clinical Trial to Evaluate the Safety, Reactogenicity and Immunogenicity of a 2-dose Ebola Vaccine Regimen of Ad26.ZEBOV Followed by MVA-BN-Filo in Healthy Pregnant WomenStatus: Completed, Estimated PCD: 2023-03-02
Product
DenosumabProduct
HCP2202Clinical trial
A Phase 1, Randomized, Blinded, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of ALXN1210 Administered Intravenously to Healthy SubjectsStatus: Completed, Estimated PCD: 2016-09-01
Product
VehicleProduct
SIPS-2209-1Product
SIPS-2209-2Product
TelmisartanClinical trial
Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses (40 mg Telmisartan / 12.5 mg HCTZ to 80 mg Telmisartan / 12.5 mg HCTZ) and Multiple Oral Doses (80 mg Telmisartan / 12.5 mg HCTZ) of Drug in Healthy Male VolunteersStatus: , Estimated PCD: 2004-02-15
Clinical trial
A Phase 1, Randomized, Double Blind, Placebo Controlled, Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of Single and Multiple Ascending Doses of MBX 2109 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-06-20
Clinical trial
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Doses of BI 655064 (Buffer Solution for Injection) in Healthy Chinese and Japanese Male Volunteers (Randomised, Double-blind, Placebocontrolled Within Dose Groups, Clinical Phase I Study)Status: Completed, Estimated PCD: 2014-05-14
Clinical trial
A Relative Bioavailability Study of 40 mg Benazepril Hydrochloride Tablets Under Non-Fasting ConditionsStatus: Completed, Estimated PCD: 2001-03-01
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CORT125236Clinical trial
A Phase I Adaptive Dose, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Orally Administered CORT125236 in Healthy Subjects, With an Optional Pharmacological Effects CohortStatus: Completed, Estimated PCD: 2023-02-03
Clinical trial
Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Assess the Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of Compound LB54640 in Healthy Overweight and Obese SubjectsStatus: Completed, Estimated PCD: 2022-03-30
Clinical trial
A Phase I, Pharmacokinetics, Safety and Tolerability Study of Single and Multiple Oral Doses of Safinamide in Healthy Adult Chinese VolunteersStatus: Completed, Estimated PCD: 2021-08-20
Clinical trial
An Open Label Randomized, Single Dose, Three-way, Partial Replicate Bioequivalence Study to Determine the Bioequivalence of Solifenacin Succinate & Mirabegron From Mirfenacin MR 5/50 mg Extended Release Tablets (Hikma Pharma, Egypt) Versus Vesicare 5 mg Film Coated Tablets & Betmiga 50 mg Prolonged-Release Tablets (Astellas Pharma Europe B.V, the Netherlands / Astellas Pharma Europe B.V, the Netherlands)Status: Completed, Estimated PCD: 2022-07-25
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CiprofloxacinClinical trial
A PHASE 1, OPEN-LABEL, FIXED-SEQUENCE STUDY TO EVALUATE THE EFFECT OF ITRACONAZOLE AND CYCLOSPORINE ON THE SINGLE-DOSE PHARMACOKINETICS OF PF-07081532 IN OVERWEIGHT OR OBESE ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2023-05-29
Clinical trial
Safety, Tolerability and Pharmacokinetics of Single Rising Oral Doses of BI 764122 (Single-blind, Partially Randomised, Placebo-controlled, Parallel (Sequential) Group Design) and the Effect of Food on BI 764122 (Open-label, Randomised, Single-dose, Two-period, Two-sequence Crossover Design) in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2019-08-12
Clinical trial
A Single-Ascending Dose, Safety, Tolerability, and Pharmacokinetic Study of LY3462817 in Healthy Japanese and Non-Japanese ParticipantsStatus: Completed, Estimated PCD: 2023-03-08
Clinical trial
Phase 1, Open-label, Single Sequence, Two-Period Crossover Trial to Evaluate the Effect of Tepotinib on CYP3A by Investigating the PK of the CYP3A Substrate Midazolam in Healthy SubjectsStatus: Completed, Estimated PCD: 2018-10-25
Clinical trial
Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IA-14069 in Healthy Subjects, With an Extension to Explore Any Drug-Drug Interaction Potential With Methotrexate (Part 1), and in Patients With Rheumatoid Arthritis, With Preliminary Assessment of Efficacy in Patients (Part 2)Status: Recruiting, Estimated PCD: 2024-09-01
Clinical trial
A Phase I Clinical Trial to Evaluate Safety, Tolerability and Pharmacokinetics of EB-203 Eye Drops in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-10-07
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EuthyroxProduct
DA-1229_01Clinical trial
A PHASE 1, OPEN-LABEL, RANDOMIZED, CROSSOVER, SINGLE DOSE STUDY TO DETERMINE THE BIOEQUIVALENCE OF 12.2 MG TAFAMIDIS FREE ACID TABLETS AND COMMERCIAL 20 MG TAFAMIDIS MEGLUMINE CAPSULES ADMINISTERED UNDER FASTED CONDITIONS AND THE EFFECT OF FOOD ON ORAL BIOAVAILABILITY OF 12.2 MG TAFAMIDIS FREE ACID TABLETS IN HEALTHY ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2022-12-18
Clinical trial
A Randomized, Open-label, Single-dose, Two-sequence, Two-period, Cross-over Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of L04TD1 and L04RD1 in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2022-10-09
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CG100649Clinical trial
A Randomized, Open, Crossover Clinical Study to Investigate the Effects of Ketoconazole on the Pharmacokinetics of CG100649 in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2010-03-01
Product
LY3971297Clinical trial
Pharmacokinetics and Safety of BPDO-1603 or BPDO-16031 and BPDO-16033 Administration in Healthy Adults. Randomized, Open-label, Single-dose, Cross-over, Phase 1 StudyStatus: Completed, Estimated PCD: 2023-02-21
Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics of Jiashen Tablets in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-04-09
Clinical trial
Study Evaluating the Mass Balance and Biotransformation of Single Dose [14C]Iruplinalkib (WX-0593) In Healthy Male VolunteersStatus: Completed, Estimated PCD: 2020-12-15
Clinical trial
Title of Study: A First-in-Human, Phase 1, Randomized, Double-Blind, Single Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of EI-001 in Healthy VolunteersStatus: Recruiting, Estimated PCD: 2022-12-01
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, SPONSOR-OPEN, PLACEBO-CONTROLLED, SINGLE AND MULTIPLE-DOSE STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND PHARMACOKINETICS OF PF-07612577 (PF-06264006 [CTB] + PF-07338233 [AVP]) IN HEALTHY ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2023-06-23
Product
BismuthProduct
AmoxicilliClinical trial
Effects of MIB-626 (β-Nicotinamide Mononucleotide) With and Without A High-Intensity Multi-Dimensional Exercise Training Program on Physical Performance, Muscle Bioenergetics, and Neuropsychological Performance in Highly Fit Young AdultsStatus: Recruiting, Estimated PCD: 2025-04-01
Clinical trial
A Phase 1, Open-Label, Single-Dose Bioequivalence Study of Injections of Lebrikizumab Using a 2-mL Pre-Filled Syringe With Needle Safety Device and an Investigational 2-mL Autoinjector in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-02-11
Clinical trial
A Phase 0, Double-Blind, Randomized, Placebo-Controlled, Crossover Study to Assess Ketamine-induced Changes in ERP Biomarkers in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-12-12
Clinical trial
A Phase I, Double-Blind, Randomised, Adaptive-designed Study to Assess the Pharmacokinetics and Safety of BLU-5937 in Healthy Adult Japanese and Caucasian Subjects Following Single and Multiple Oral DosesStatus: Completed, Estimated PCD: 2021-10-22
Clinical trial
A Phase 1, Open-Label, Single-Dose, Randomized, 2-Period Crossover Study to Assess the Bioequivalence of Two Pacritinib Drug Product Formulations (Phase 3 Clinical Trial [P3CT] Formulation [Reference] and Final Market Image [FMI] Formulation [Test]) Following Oral Administration in Healthy SubjectsStatus: Completed, Estimated PCD: 2015-09-01
Product
AlteplaseClinical trial
Bioequivalence of Alteplase Derived From Two Different Manufacturing Processes Following Intravenous Administration in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2021-06-21
Product
URC102Product
Epoetin AlfaClinical trial
A Phase I Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and Safety After Administration of NVP-2002 and Co-administration of NVP-2002-R1 and NVP-2002-R2 in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2023-04-25
Product
L04TD2Product
PacritinibClinical trial
A Randomized, Double-blind, Placebo-controlled Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Doses of FTP 198 in Healthy VolunteersStatus: Completed, Estimated PCD: 2021-02-26
Clinical trial
A Phase 1 Study to Investigate the Pharmacokinetics and Pharmacodynamics of JNJ-77474462 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2021-05-30
Product
AnakinraProduct
BravamaxClinical trial
The Effect of Multiple Doses of Esomeprazole on the Single-dose Pharmacokinetics of BI 1819479 Following Oral Administration in Healthy Male Subjects (an Open-label, Randomized, Two-way Cross-over Study)Status: Completed, Estimated PCD: 2023-01-23
Clinical trial
A Randomized, Open-label, Single Dose, Cross-over Clinical Trial to Compare the Safety, Tolerability, and Pharmacokinetic Properties of DA-5216 and DA-5216-R and to Evaluate the Food Effect on DA-5216 in Healthy Adult Subjects.Status: Recruiting, Estimated PCD: 2022-10-01
Product
CRESTOR®Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single Center Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of REGN7999, a TMPRSS6 Antagonist, in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2023-08-24
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ACT-1004-1239Clinical trial
Interventional, Randomized, Double-Blind, Sequential-Group, Placebo-Controlled, Single-Ascending Oral Dose Study Investigating the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of Lu AG06474 and Open-Label, Cross-Over Study to Investigate Intra-Subject Variability and the Effect of Food in Healthy Young MenStatus: Completed, Estimated PCD: 2022-12-22
Clinical trial
A Phase 1 Study to Confirm the Single- and Multiple-dose Pharmacokinetics and to Evaluate Food Effect of Vapendavir in Healthy Participants and Participants With COPDStatus: , Estimated PCD: 2023-08-01
Product
[18F]-JNJ-70099731Clinical trial
Comparative Randomized, Single Dose, Three-way, Three-sequence, Two Treatment, Partial Replicate, Crossover, Open-label Study to Determine the Bioequivalence of Nirmatrelvir & Ritonavir From Copaxid 150 +100 mg Tablets (Eva Pharma, Egypt) Versus Paxlovid 150 + 100 mg Film Coated Tablets (Pfizer Europe, Belgium)Status: Completed, Estimated PCD: 2022-09-04
Clinical trial
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, THIRD-PARTY OPEN, PLACEBO-CONTROLLED, DOSE ESCALATING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS AND PHARMACODYNAMICS FOLLOWING SINGLE SUBCUTANEOUS DOSE OF PF-06480605 IN JAPANESE HEALTHY PARTICIPANTSStatus: Completed, Estimated PCD: 2020-11-11
Product
CHR-2797Clinical trial
Open-label, Nonrandomized, Single-dose, Parallel-group, Safety, Tolerance, and Pharmacokinetic Study of LOXO-292 Administered to Fasted Hepatically Impaired Male and Female Subjects and Fasted Matched-control Healthy SubjectsStatus: Completed, Estimated PCD: 2019-10-04
Clinical trial
A Bioequivalence Study of Subcutaneous Injections of Mirikizumab Reference Solution Using an Investigational 1-mL Autoinjector and Mirikizumab Test Solution Formulation Using an Investigational 1-mL Autoinjector in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-02-20
Product
BI 1015550 TF2Product
SudapyridineProduct
TdapClinical trial
A Phase 1, Blinded, Randomized, Placebo-controlled, First-in-human Study of Orally Administered JNJ-64457744 to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics After Single and Multiple Ascending DosesStatus: Terminated, Estimated PCD: 2023-03-14
Product
TDM-180935Product
BCD-264Clinical trial
A Randomized, Double-Blind, Comparative Clinical Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of Single Intravenous Infusion of BCD-264 and Darzalex® in Healthy VolunteersStatus: Completed, Estimated PCD: 2023-08-15
Product
Matching PlaceboProduct
DarzalexProduct
LY3471851Clinical trial
A Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of LY3471851 in Japanese and Caucasian Healthy SubjectsStatus: Completed, Estimated PCD: 2020-03-06
Product
LY3337641Product
First Test ConcorProduct
HZN-457Clinical trial
A Phase I/II, Randomized, Single-Blind, Placebo-Controlled Escalating Double-Dose Safety Study of an Intramuscular Influenza Vaccine (Multimeric-001) Injected to Healthy VolunteersStatus: Completed, Estimated PCD: 2009-10-01
Product
Multimeric-001Clinical trial
Investigation of Metabolism and Pharmacokinetics and Absolute Bioavailability of BI 685509 (C-14) After Intravenous and Oral Administration in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2022-11-17
Clinical trial
The Effect of Multiple Doses of BI 730357 on the Single Dose Pharmacokinetics of Caffeine, Warfarin, Omeprazole and Midazolam Administered Orally as a Cocktail in Healthy Subjects (an Open-label, Two-period Fixed Sequence Design Trial)Status: Completed, Estimated PCD: 2021-03-17
Clinical trial
Single-center, Double-blind (ACT-246475), Open-label (Clopidogrel, Prasugrel, and Ticagrelor), Placebo-controlled, Randomized, Two-way Crossover Study to Investigate the Pharmacodynamics, Safety, and Tolerability of a Single Oral Dose of Clopidogrel or, Prasugrel, or Ticagrelor When Administered After a Single Subcutaneous Dose of the P2Y12 Antagonist ACT-246475 in Healthy Male and Female SubjectsStatus: Completed, Estimated PCD: 2019-05-20
Clinical trial
Comparative Randomized, Single Dose, Two-Way Crossover Open Label Study To Determine The Bioequivalence Of 5 mg/mL Tramadol Hydrochloride Oral Solution (08P1902F0) Relative To Contramal® (100 mg/mL Oral Solution) After An Oral AdministrationStatus: Completed, Estimated PCD: 2023-02-26
Clinical trial
A Randomized, 3-Treatment, 3-Period, 6-Sequence, Crossover, Placebo- and Active-Controlled, Double-Blind for ALXN1840 (Open-Label for Moxifloxacin) Thorough QT/QTc Study to Evaluate ALXN1840 on Cardiac Repolarization in Healthy AdultsStatus: Completed, Estimated PCD: 2021-03-24
Product
ConcorProduct
DexamethasoneProduct
TDVProduct
CORT125134Clinical trial
A Phase 1, Randomized, Open-Label, Single-Dose, Three-Way Crossover Study to Evaluate The Effect of Food on the Oral Bioavailability of Relacorilant in Healthy SubjectsStatus: Completed, Estimated PCD: 2020-11-16
Clinical trial
A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SHR-2001 After a Single Subcutaneous Injection in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2023-12-20
Clinical trial
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Multiple-Ascending Dose Study of TT-00920 in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-11-30
Product
CVI-HBV-001Clinical trial
Assessment of [18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy SubjectsStatus: Completed, Estimated PCD: 2023-05-09
Clinical trial
Adenosine Receptors From Genes to Behavior: Neurobehavioral Correlates of Caffeine on Anxiety, Avoidance, Decision-Making and Interoception in Healthy Individuals and Panic Disorder.Status: Not yet recruiting, Estimated PCD: 2025-03-01
Clinical trial
A Phase 1a/1b Study of OPT101 in Healthy VolunteersStatus: Recruiting, Estimated PCD: 2024-06-30
Product
AlbuterolProduct
CAF®10bProduct
GB001Product
0.20% CHX GelClinical trial
Muscarinic M1 Receptor Availability and Cognition in SchizophreniaStatus: Completed, Estimated PCD: 2023-10-31
Product
11C-EMOProduct
BI-409306Product
DefinityProduct
763SIP8/MPLA-5 vaccineClinical trial
Single-Dose Fasting Bioequivalence Study of Topiramate Sprinkle Capsules (25 mg; Mylan) and Topamax® Sprinkle Capsules (25 mg; Ortho-McNeil Neurologics) in Healthy Volunteers Dosed With ApplesauceStatus: Completed, Estimated PCD: 2005-12-01
Product
Intranasal PlaceboClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Pioglitazone HCl Tablets (45 mg; Mylan) to Actos® Tablets (45 mg; Takeda) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-03-01
Product
ActosClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Metformin Hydrochloride ER Tablets (500 mg; Mylan) and Glucophage® XR Tablets (500 mg; Bristol-Myers Squibb) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-10-01
Product
Metformin HydrochlorideClinical trial
Effects of Psilocybin on Electrophysiology and the Dynamic Content of ThoughtStatus: Recruiting, Estimated PCD: 2024-12-31
Clinical trial
Methods to Identify and Treat Severe Asthma Patients Project 2: Airway pH PhenotypingStatus: Recruiting, Estimated PCD: 2027-06-30
Product
AzithromycinProduct
Intranasal placeboProduct
Bacillus Calmette-GuerinClinical trial
Studying the Role of Brain Molecules for Decision MakingStatus: Completed, Estimated PCD: 2021-12-13
Clinical trial
Profiling the Skin Microbiome in Response to Altreno in Acne PatientsStatus: Completed, Estimated PCD: 2022-08-22
Clinical trial
Comparison of the Effects of PEX20 (Oral Psilocin), PEX30 (Sublingual Psilocin), and PEX10 (Oral Psilocybin) in Healthy AdultsStatus: Recruiting, Estimated PCD: 2025-03-01
Clinical trial
Single-Dose Fed Bioequivalence Study of Albuterol Sulfate Extended-Release Tablets (8 mg; Mylan) and VoSpire® ER Tablets (8 mg; Pliva) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-10-01
Clinical trial
Healthy Aging Through Dietary Intervention: Multiparametric Quantification of Function and Pathophysiology of the Aging Heart and Prevention of Age-associated Decline in Exercise Capacity Through Dietary FlavanolsStatus: Completed, Estimated PCD: 2022-09-30
Product
ASN51Drug
FilgrastimClinical trial
A Randomized, Double-blind, Placebo-controlled, Dose-escalation Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics, and the Impact of Food on Pharmacokinetics of HS-10398 in Healthy Participants, and a Clinical Trial to Assess the Pharmacokinetic Characteristics of HS-10398 in Participants With Kidney DysfunctionStatus: Not yet recruiting, Estimated PCD: 2025-01-31
Clinical trial
An Open Label, Randomized, Three-treatment, Three-sequence, Three-period, Cross-over, Pharmacokinetic and Adhesion Performance Study of Lidocaine Patch 36 mg/Patch (1.8%) in Fasting, Healthy, Adult, Human Subjects, With Physical Exercise, Heat and Normal Conditions.Status: Completed, Estimated PCD: 2016-01-25
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Azithromycin Tablets (600 mg; Mylan) to Zithromax® Tablets (600 mg; Pfizer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-05-01
Product
Paxil CRClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Olanzapine Tablets (5 mg; Mylan) and Zyprexa® Tablets (5 mg; Eli Lilly) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-07-01
Clinical trial
Glutamatergic Mechanisms of Psychosis and Target Engagement: Aim2Status: , Estimated PCD: 2025-08-15
Product
Midodrine HClClinical trial
Single-Dose Fed Bioequivalence Study of Paroxetine Hydrochloride Tablets (40 mg; Mylan) and Paxil® Tablets (40 mg; GSK) in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2006-12-01
Product
ClinisolProduct
VasopressinProduct
NaloxoneProduct
AciphexClinical trial
Double-blind, Randomized, With an Active Control Vaccine, Phase I Clinical Trial for Evaluation of Safety and Immunogenicity of a Recombinant Inactivated COVID-19 Vaccine in Adults in Brazil - ADAPTCOVStatus: Completed, Estimated PCD: 2021-12-10
Product
IBI355Product
QuercetinClinical trial
Single-Dose Fasting Bioequivalence Study of Fluoxetine Capsules (40 mg; Mylan) and Prozac Pulvules (40 mg; Dista) in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2006-04-01
Product
ProzacProduct
Quinapril HydrochlorideProduct
AccuprilClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Levothyroxine Sodium Tablets (200 mg; Mylan) to Synthroid Tablets (200 mg; Abbott) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-03-01
Clinical trial
A Phase I Clinical Study to Evaluate the Safety, Biodistribution, Radiation Dose and Pharmacokinetics of 68Ga-HX01 Injection for PET ImagingStatus: Completed, Estimated PCD: 2023-07-20
Product
68Ga-HX01Clinical trial
The Effect of Obeticholic Acid on Gut Microbiota, Gastric Motility, Accommodation, Gastrointestinal Peptide in Healthy VolunteersStatus: Recruiting, Estimated PCD: 2023-07-22
Product
ProscarClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Ciprofloxacin Extended-Release Tablets (1000 mg; Mylan) and Cipro® XR Tablets (1000 mg; Bayer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-10-01
Product
Cipro XRClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Fexofenadine Tablets (180 mg; Mylan) and Allegra® Tablets (180 mg; Aventis) in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2003-11-01
Product
Blood SamplesClinical trial
A Randomized, Single-Blind, Investigator Initiative Trial Study of Remimazolam Versus Midazolam for Sedation in Diagnostic Upper Gastrointestinal EndoscopyStatus: Not yet recruiting, Estimated PCD: 2023-12-31
Product
RemimazolamClinical trial
Acute Effects of 3,4-methylenedioxymethamphetamine (MDMA) With and Without a Booster Dose (MDMA-booster Study)Status: Recruiting, Estimated PCD: 2025-12-31
Product
SemaglutideDrug
antibioticsClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Cetirizine HCl Tablets (10 mg; Mylan) and Zyrtec® (10 mg; Pfizer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Product
ZyrtecClinical trial
The Effects of Low Dose Ketamine on Cardiovascular FunctionStatus: Terminated, Estimated PCD: 2021-05-28
Product
SalineClinical trial
A Single-center, Open-label, Single-dose, Randomized, 3-way Crossover Phase 1 Study in Healthy Adult Participants to Assess the Bioequivalence of the Combination of Macitentan/Tadalafil (10 mg/20 mg) Administered as a Fixed Dose Combination Formulation Compared to the Reference Free Combination of 10 mg Macitentan (Opsumit®) and 20 mg Tadalafil (Adcirca®) as Well as the Food Effect of the Fixed-dose Combination FormulationStatus: Completed, Estimated PCD: 2022-05-13
Product
Macitentan + TadalafilProduct
Nirmatrelvir + RitonavirProduct
NM8074Product
DecitabineProduct
Lasix®Product
EmraclidineClinical trial
A First-in-human, Randomized, Double-blind, Parallel-group Study to Evaluate the PK, Safety, Tolerability, Immunogenicity, and PD Profile of a Single Intravenous Dose of TUR03 Compared With Soliris® in Healthy Adult Male ParticipantsStatus: Recruiting, Estimated PCD: 2024-07-23
Clinical trial
An Open-Label, Parallel-Group, Single-Dose Study to Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of JNJ-42847922 in Adult ParticipantsStatus: Completed, Estimated PCD: 2021-11-19
Clinical trial
A Phase 1, Open-label Trial to Evaluate the Effect of Food on the Pharmacokinetics of Emraclidine in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2023-07-26
Clinical trial
A Phase 1, Single-Center, Randomized, 3-Period Crossover Study to Evaluate the Relative Bioavailability of WTX101 in Healthy Subjects After Single Dose Administration of a Non-Coated Formulation With and Without a Proton Pump Inhibitor and With a Proton Pump Inhibitor With and Without FoodStatus: Completed, Estimated PCD: 2014-03-24
Clinical trial
Effect of Injection Site on the Relative Bioavailability of a Single Dose of Tirzepatide in Subjects With Low and High Body Mass IndicesStatus: Completed, Estimated PCD: 2020-04-03
Clinical trial
A Randomised, Single-blind, Placebo-controlled Trial to Investigate Safety, Tolerability, and Pharmacokinetics of Single Rising Doses of BI 3000202 Administered as Tablet to Healthy Male Subjects, and a Randomised, Open-label, Single-dose, Two-way Cross-over Relative Bioavailability Comparison of BI 3000202 as Tablet With and Without Food in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2023-11-13
Clinical trial
A Randomized, Double-Blind, Multiple Dose, 3-way Crossover, Exploratory Study to Assess the Pharmacodynamic Effects of SAGE-217 Capsules in Healthy Adults Using a 5-hour Phase Advance Model of InsomniaStatus: Completed, Estimated PCD: 2017-12-04
Product
SAGE-217Product
REGN14284Clinical trial
The Relative Bioavailability of Two Terbinafine HCl 250 mg Tablet Formulations Under Non-Fasting ConditionsStatus: Completed, Estimated PCD: 2002-01-01
Product
HEC53856Product
ReciferceptClinical trial
A Relative Bioavailability Study of 100 mg Flavoxate Hydrochloride Tablets Under Fasting ConditionsStatus:
Product
NiclosamideProduct
Allyl IsothiocyanateClinical trial
A Phase I, Open Label, Single Dose Study to Evaluate the Mass Balance of 14C-Napabucasin in Healthy Adult Male SubjectsStatus: Completed, Estimated PCD: 2018-06-02
Product
PhencynonateProduct
TR-01-IRClinical trial
Tracking Peripheral Immune Cell Infiltration of the Brain in Central Inflammatory Disorders Using [Zr-89]Oxinate-4-labeled Leukocytes.Status: Recruiting, Estimated PCD: 2024-10-05
Product
Xultophy®Product
ZolmitriptanClinical trial
General and Anxiety-Linked Influence of Acute Serotonin Reuptake Inhibition on Neural Responses Associated With Attended Visceral SensationStatus: Completed, Estimated PCD: 2018-11-13
Product
Fluticasone propionateClinical trial
Acute Effects of 2C-B Compared With MDMA and Psilocybin in Healthy SubjectsStatus: Recruiting, Estimated PCD: 2024-06-30
Clinical trial
Endothelial Derived Hyperpolarization Factor and Regulation of Cerebral and Muscle Blood FlowStatus: Recruiting, Estimated PCD: 2024-06-01
Clinical trial
A PHASE 1, OPEN-LABEL, SINGLE-DOSE, PARALLEL GROUP STUDY TO EVALUATE THE PHARMACOKINETICS OF PF-06882961 IN PARTICIPANTS WITH TYPE 2 DIABETES MELLITUS WITH VARYING DEGREES OF RENAL IMPAIRMENT RELATIVE TO PARTICIPANTS WITHOUT RENAL IMPAIRMENTStatus: Completed, Estimated PCD: 2022-02-18
Clinical trial
Cannabis and Polysubstance Use: Response Inhibition and Stress ExposureStatus: Recruiting, Estimated PCD: 2024-12-01
Product
Cannabis oilClinical trial
The Effects of Losartan on Attention Control: An Eye-tracking StudyStatus: Recruiting, Estimated PCD: 2025-06-01
Product
Tramadol.Clinical trial
Single-Dose Fasting Bioequivalence Study of Levothyroxine Sodium Tablets (300 mcg; Mylan) to Synthroid® Tablets (300 mcg; Abbott)Status: Completed, Estimated PCD: 2007-04-01
Product
Levothyroxine SodiumProduct
SynthroidProduct
Late Dinner tracerClinical trial
Multi-level Molecular Profiling of Stress Exposure Under Standardized Food Intake: A Clinical StudyStatus: Recruiting, Estimated PCD: 2024-12-31
Product
JLP-2004Clinical trial
A Phase 1, Participant- and Investigator-blinded, Randomized, Single-dose Study to Investigate the Safety and Pharmacokinetics of Lebrikizumab in Healthy Chinese ParticipantsStatus: Recruiting, Estimated PCD: 2024-09-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Glipizide and Metformin HCl Tablets (5 mg/500 mg; Mylan) to Metaglip® Tablets (5 mg/500 mg; Bristol-Myers Squibb) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-06-01
Clinical trial
Single-Dose Fed Bioequivalence Study of Nadolol/Bendroflumethiazide Tablets (80 mg/5 mg; Mylan) and Corzide® Tablets (80 mg/5 mg; King) in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-08-01
Product
Empagliflozin + LinagliptinProduct
RPV LAProduct
Y-2Clinical trial
Alterations in the Human Microbiome With Commonly Used Topical MedicationsStatus: Recruiting, Estimated PCD: 2026-09-28
Clinical trial
Single-Dose Food in Vivo Bioequivalence Study of Amlodipine and Benazepril HCl Capsules (10 mg/20 mg; Mylan) to Lotrel® Capsules (10 mg/20 mg; Novartis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-06-01
Clinical trial
Steady-State Bioequivalence Study of Extended Phenytoin Sodium Capsules (100 mg; Mylan) and Dilantin® Kapseals® (100 mg; Pfizer) in Healthy Adult VolunteersStatus: Completed, Estimated PCD: 2005-12-01
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ZoloftClinical trial
The Effect of Supplementation of Vitamin D3 on Inflammation Induced by 100 km Running, Iron Metabolism and ErythropoiesisStatus: Completed, Estimated PCD: 2022-11-01
Clinical trial
Effects of Perampanel on Neurophysiology Test PerimetersStatus: Completed, Estimated PCD: 2021-11-29
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Levothyroxine Sodium Tablets (300 μg; Mylan) to Synthroid® Tablets (300 μg; Abbott) in Healthy Volunteers.Status: Completed, Estimated PCD: 2003-06-01
Clinical trial
Effects of Caffeine on Anxiety, Emotional Processing, Approach-avoidance Behavior, and Interoception in Panic Disorder - a Double Blind Randomized Controlled StudyStatus: Completed, Estimated PCD: 2023-03-19
Product
SyntocinonClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Metolazone Tablets (5 mg; Mylan) and Zaroloxyn® Tablets (5 mg; Celltech) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-11-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Ondansetron Tablets (24 mg; Mylan) and Zofran® Tablets (24 mg; GSK) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-07-01
Clinical trial
A Randomized, Double-Blind, Placebo-Controlled, Single-Administration, Dose-Escalation Study of Entolimod on Immunosenescence in Healthy Geriatric Subjects Receiving Influenza VaccinationStatus: Completed, Estimated PCD: 2022-03-30
Clinical trial
Phase I Study to Evaluate the Drug-Drug Interaction (DDI) Between JMKX000623 Tablets and Metformin Hydrochloride Tablets in Healthy Chinese SubjectsStatus: Completed, Estimated PCD: 2023-11-06
Clinical trial
TGIR (Traditional Gastrointestinal Remedy) Randomized Placebo-controlled Healthy Subject StudyStatus: Recruiting, Estimated PCD: 2023-12-01
Clinical trial
Impact of Insulin on Sympathetic Nervous System-mediated Peripheral VasoconstrictionStatus: Completed, Estimated PCD: 2021-06-25
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Sodium thiosulfateClinical trial
The Assessment for Effect of Red Ginseng Extract on Changes in Indicators of Immune Function in Vietnamese Healthy Volunteers: The Double-blind, Randomized, Placebo-controlled TrialStatus: Completed, Estimated PCD: 2022-12-03
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Mescaline + KetanserinProduct
MercaptopurineProduct
SetmelanotideClinical trial
Influence of Artificial Tears on Corneal Parameter Measurement Using Three Different Devices: Scheimpflug-, Keratometry - and Placido-technologyStatus: Completed, Estimated PCD: 2022-04-22
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Multiple dose placeboClinical trial
A Randomized, Crossover, Open-label Phase 1 Study of Glyceryl Tri-(4-phenylbutyrate) (GT4P)Status: Completed
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HPN-100Clinical trial
A Randomized, Open-label, 2-period, 2-sequence Cross-over Trial to Compare the Pharmacokinetics of Tralokinumab of Two Presentations in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-12-29
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FadraciclibClinical trial
A Phase 1, Double-Blind, Placebo-Controlled, Safety, Tolerability and Pharmacokinetics Study of PRA052 in Healthy VolunteersStatus: Completed, Estimated PCD: 2024-02-21
Clinical trial
Relative Bioavailability of BI 1810631 Following Oral Administration Under Fed and Fasted Conditions in Healthy Male Subjects (an Open-label, Randomised, Single-dose, Two-way Crossover Trial).Status: Completed, Estimated PCD: 2024-01-02
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PF-06823859Product
Dabigatran EtexilateProduct
LamotrigineClinical trial
Relative Bioavailability of BI 1323495 Following Oral Administration Under Fed and Fasted Conditions in Healthy Male Subjects (an Open-label, Randomised, Single-dose, Two-period, Two-sequence Crossover Study)Status: Completed, Estimated PCD: 2019-03-03
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ALXN2030Product
RifampinClinical trial
A PHASE 1, OPEN-LABEL, SINGLE DOSE STUDY TO INVESTIGATE THE PHARMACOKINETICS, SAFETY AND TOLERABILITY OF ZAVEGEPANT INTRANASAL ADMINISTRATION IN HEALTHY CHINESE ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2023-12-12
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ZavegepantProduct
BI 655064Clinical trial
A Randomized, Double-blind, Placebo-controlled Phase I Clinical Trial Evaluating the Safety and Pharmacokinetic Profile of RSS0393 Ointment as a Single and Multiple Dose Ascending Local Dermal Administration in Healthy and Adult Subjects With PsoriasisStatus: Not yet recruiting, Estimated PCD: 2024-08-01
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DA-7503Product
[14C]-LY3473329Clinical trial
A Study to Evaluate Tirzepatide Concentrations in Breastmilk Following Administration of Single Dose of Tirzepatide by Subcutaneous Injection in Healthy Lactating FemalesStatus: Completed, Estimated PCD: 2024-03-12
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LY3872386Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Zonisamide Capsules (100 mg; Mylan) to Zonegran® Capsules (100 mg; Elan) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-12-01
Clinical trial
A Phase 2A, Randomized, Double-blind, Placebo-controlled, Single Dose, Sequential Group Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PB2452 With Ticagrelor Pretreatment in Older and Elderly Subjects and With High-Dose Ticagrelor Pretreatment in Healthy Younger SubjectsStatus: Completed, Estimated PCD: 2019-10-09
Product
AYP-101Product
VG-3927Product
ASC42Clinical trial
Phase I Clinical Study, Evaluating Safety and Tolerability of PRO-232 an Ophthalmic Solution, Versus Placebo, When Applied to the Ocular Surface of Ophthalmologically and Clinically Healthy Volunteers.Status: Not yet recruiting, Estimated PCD: 2025-06-30
Clinical trial
Pharmacokinetics of R-BI 1015550 After Single Oral Doses of BI 1015550 in Japanese Healthy Male Subjects (Open-label, Non-randomised, and Parallel Group Design)Status: Completed, Estimated PCD: 2024-02-07
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MADProduct
K-001Product
ExelonProduct
VodobatinibClinical trial
Metabolism and Pharmacokinetics of [14C]-BI 409306 After Administration of 25 mg [14C]-BI 409306 as Oral Solution in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2015-12-11
Clinical trial
An Open-Label, 3-Period, Fixed Sequence Study to Evaluate the Effect of an H2 Antagonist and a Proton Pump Inhibitor on the Single Dose Pharmacokinetics of LOXO-292 in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2019-09-03
Clinical trial
A Dose Escalation Phase I Clinical Study to Evaluate the Tolerability and Safety of a Single Intravenous Injection IBI311 in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-11-23
Clinical trial
The Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 1810631 in Healthy Male Subjects (an Open-label, Two-period, Fixed-sequence Trial)Status: Completed, Estimated PCD: 2023-06-12
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KAND567Clinical trial
A Randomized, Double-blind, Placebo Control, Phase 1 Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) of MT200605 for Injection in Healthy Subjects.Status: , Estimated PCD: 2024-07-30
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Vesicare & BetmigaClinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Sequential, Dose-Escalating Trial to Evaluate the Safety and Tolerability of Oral Verdinexor (KPT-335) in Healthy Adult SubjectsStatus: Terminated, Estimated PCD: 2015-10-01
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CD388Clinical trial
A Randomised, Single-blind, Placebo-controlled Trial in Parallel Group Design to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Oral Doses of BI 1356225 Administered as Oral Solution and Tablets to Healthy Male Subjects, and a Randomised, Open-label, Single-dose, Two-way Cross-over Bioavailability Comparison of BI 1356225 as Tablet With and Without FoodStatus: Completed, Estimated PCD: 2019-12-23
Product
LB64640Clinical trial
A Multiple Dose Study in Healthy Overweight and Obese Participants to Investigate the Safety, Tolerability, and Pharmacokinetics of LY3502970Status: Completed, Estimated PCD: 2022-09-09
Clinical trial
Relative Bioavailability of Intended Commercial Formulations (iCF) of BI 730357 Versus BI 730357 Trial Formulation 1 and Bioavailability Comparison of Three Different iCF Batches Following Oral Administration in Healthy Subjects (an Open-label, Single-dose, Randomised, 2-way and 3-way Crossover Trial)Status: Completed, Estimated PCD: 2019-06-21
Clinical trial
A Pilot Study in Healthy Volunteers to Assess the Rate and Extent of Absorption of Hydrocodone From 20 mg Hydrocodone Bitartrate Extended-Release (HC-ER) Capsules, in Both Fed and Fasted StatesStatus: Completed, Estimated PCD: 2002-06-01
Clinical trial
A Phase 1 Randomized, Double Blinded, Placebo-Controlled Single Dose Escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of 611 in Adult Healthy Male and Female VolunteersStatus: Completed, Estimated PCD: 2021-08-13
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HCP2001Clinical trial
A Randomized, Open Label, Single Dose, 4-period Replicate Crossover Clinical Trial to Evaluate the Pharmacokinetic Characteristics and Safety After Administration of a Fixed-dose Combination Drug of HCP2202 or Co-administration of RLD2202 and RLD2203 in Healthy Volunteers Under Fasting ConditionsStatus: Completed, Estimated PCD: 2022-11-10
Clinical trial
A Randomized, Double-blind, Placebo-controlled First-in-Human Study of Single and Multiple Doses of ALXN2080 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-04-24
Clinical trial
An Open Label, Randomized, Single Dose, Cross-over ,Two-group Study to Evaluate the Pharmacokinetics and Safety of DA-1229_01 2.5/500mg in Healthy Subjects at Fasting StateStatus: Not yet recruiting, Estimated PCD: 2023-04-14
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Lu AF87908Product
PRT064445Clinical trial
A Phase 1, Randomized, Blinded, Placebo Controlled, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of ALXN1210 Administered Intravenously to Healthy SubjectsStatus: Completed, Estimated PCD: 2015-03-13
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CenerimodProduct
T8Product
T9Product
T10Clinical trial
A Phase 1, Open-label Two-part Study of the Absorption, Metabolism, Excretion, and the Absolute Bioavailability of [14C]-LOXO-783 in Healthy Adult SubjectsStatus: Not yet recruiting, Estimated PCD: 2024-01-11
Product
LY3462817Product
ForxigaClinical trial
Effect of Itraconazole on the Pharmacokinetics of a Single Oral Dose of BI 1815368 in Healthy Male Subjects (an Open-label, Two-period Fixed-sequence Design Study)Status: Completed, Estimated PCD: 2023-10-24
Clinical trial
A Phase I, Open-label, Single-dose Trial to Investigate Metabolism and Pharmacokinetics of BI 730357 BS (C-14) Administered as Oral Solution in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2018-11-13
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PF-06821497Clinical trial
AN INTERVENTIONAL, PHASE 1, OPEN-LABEL, 2-ARM PARALLEL STUDY TO INVESTIGATE THE ABSORPTION, METABOLISM, AND EXCRETION OF [14C]ARV-471 IN HEALTHY ADULT PARTICIPANTSStatus: Completed, Estimated PCD: 2023-07-27
Clinical trial
A Single- and Multiple-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3337641 in Japanese and Caucasian Healthy SubjectsStatus: Completed, Estimated PCD: 2017-05-25
Clinical trial
A Phase 1, Double-Blind, Randomized, Placebo-Controlled, Study to Evaluate the Safety and Tolerability of LY3537021 When Combined With GLP-1 Receptor Agonist in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-02-24
Product
LumentinClinical trial
Can Biotin Supplementation be Used to Mask hCG Abuse?Status: Completed, Estimated PCD: 2023-02-02
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[¹⁴C]-LY3437943Product
MVA-MosaicProduct
THDB0206Clinical trial
A Randomized Study to Investigate Injection-Site Pain Following Subcutaneous Injections of 2 Ixekizumab Test Formulations Compared to the Commercial Formulation Using a Pre-filled Syringe in Healthy SubjectsStatus: Terminated, Estimated PCD: 2019-07-18
Clinical trial
Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BI 1819479 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2022-12-20
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GB001 recombinant peptideProduct
A2Product
B3Product
Lu AF90103Product
EdoxabanProduct
RivaroxabanProduct
MetfoLiquid GeriaSanProduct
XolairClinical trial
Open-Label Study to Assess the Disposition of [14C]-LY3372689 Following Oral Administration in Healthy Male ParticipantsStatus: Completed, Estimated PCD: 2023-04-18
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ADL-018Product
BI matching placeboProduct
PropranololClinical trial
Single-blind, Randomized, Two-arm, Dose-response Study of DMT and Harmine in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-09-17
Clinical trial
Randomized Open-label Study to Evaluate the Pharmacokinetics and Safety of VER-01 After Single Dose With and Without Meal in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-11-17
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[¹⁴C]-LY3372689Clinical trial
A Phase I Single-blind, Randomised, Placebo-controlled, Parallelgroup Design Trial to Investigate the Safety, Tolerability, Pharmacokinetics and Harmacodynamics of Single Rising Doses of BI 3032950 Administered as Intravenous Infusion (Part A) or Subcutaneous Injection (Part B) to Healthy Male SubjectsStatus: Completed, Estimated PCD: 2023-09-21
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CholestyramineClinical trial
An Open-Label, Repeat-Dose Study to Evaluate the Pharmacokinetics of Orally Administered CORT125134 Using the Current Capsule Formulation in Healthy SubjectsStatus: Completed, Estimated PCD: 2017-11-15
Clinical trial
A Multiple Dose Study to Assess the Pharmacokinetics, Safety, and Tolerability of Tablet and Capsule Formulations of LY3502970 in Healthy Overweight and Obese ParticipantsStatus: Completed, Estimated PCD: 2023-09-14
Clinical trial
Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BI 1839100 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design)Status: Completed, Estimated PCD: 2023-06-14
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UrispasClinical trial
A Phase 1, Randomized, Open-Label, 2-Way Crossover Study to Assess the Single-Dose Pharmacokinetics of ALXN1840 Enteric-Coated Tablets at 2 Dose Strengths in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2019-10-09
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RE02Clinical trial
An Open-label, Randomized, Cross-over Study With 2 Treatments (Fasting and After Meals), 3 Periods, 2 Sequences, and an Adaptive, Two-stage Design to Evaluate the Effect of Food Intake on the Bioavailability of XC221 100 mg Tablets at a Single Dose in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-02-22
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VerapamilProduct
XC221Clinical trial
An Open-label, Multi-center, Bilateral, Human Factors Study to Evaluate the Utilization and Safety of a Novel Intracanalicular Insertion Device in Healthy SubjectsStatus: Terminated, Estimated PCD: 2022-11-01
Clinical trial
An Open-Label, Multiple-Dose Study to Investigate the Pharmacokinetics of LY3493269 Oral Formulations Administered in a Fed or Fasted State in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-06-20
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TR-01-XRRProduct
THCProduct
DMTClinical trial
Cytotoxicity of Yellow Fever Specific CD8 T Cells Following YF-17D VaccinationStatus: , Estimated PCD: 2025-02-15
Clinical trial
Short-Term Effects of Nicotinamide and Lanthanum Carbonate on Phosphorus Homeostasis in Healthy VolunteersStatus: Completed, Estimated PCD: 2017-12-01
Product
NicotinamideClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Midodrine HCl Tablets (5 mg; Mylan) and ProAmatine® Tablets (5 mg; Roberts) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-11-01
Product
MetolazoneProduct
ZaroloxynClinical trial
Effects of Experimental Sleep Disruption and Fragmentation on Study Drug Receptor Function, Receptor Agonist Analgesia, and Abuse LiabilityStatus: Recruiting, Estimated PCD: 2024-08-31
Clinical trial
A Phase II Trial Assessing Immunogenicity and Safety of COVID-19 mRNA Vaccine BNT162b2 in Adult Volunteers With no History of SARS-CoV-2 Infection Administered With Two Doses of Vaccine (D1-D29) and in Adult Volunteers With Documented History of SARS-CoV-2 Infection (of More Than 5 Months) Administered With Only One Dose of VaccineStatus: Completed, Estimated PCD: 2021-06-30
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Targeted Therapy AgentClinical trial
Does Serotonin System Stimulation Increase Pro-social Behavior? - A Comparative Pharmacological Neuroscientific Study in Healthy HumansStatus: Recruiting, Estimated PCD: 2025-04-01
Clinical trial
Sex Disparities in Hypoxic Sympatholysis and Impact of ObesityStatus: Recruiting, Estimated PCD: 2025-06-30
Product
Serotonin agonistProduct
Saline + Intralipid/HeparinDrug
R-CHOPClinical trial
Multi-modal Assessment of GABA Function in PsychosisStatus: Recruiting, Estimated PCD: 2025-02-28
Product
Single-Dose MadoparProduct
single-dose placeboClinical trial
A Randomised Crossover Study of the Pharmacokinetics, Safety and Tolerability of Two Rectal Formulations of Ceftriaxone Compared to Parenteral Ceftriaxone, in Healthy Thai Adults.Status: Not yet recruiting, Estimated PCD: 2025-04-01
Product
CeftriaxoneProduct
OCT461201Clinical trial
A 90-day, Double-blind, Placebo-controlled, Randomized, Parallel-Group Efficacy and Safety Study of an Amino Acid Supplement in AdultsStatus: Completed, Estimated PCD: 2024-01-08
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Delta-9-THCClinical trial
Safety and Efficacy of Inhaled Tissue Plasminogen Activator (tPA) for the Acute Treatment of Pediatric Plastic BronchitisStatus: Completed, Estimated PCD: 2021-03-05
Product
tPAProduct
VDJ001Product
SSS40Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Glimepiride Tablets (1 mg; Mylan) to Amaryl® Tablets (1 mg; Aventis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-12-01
Clinical trial
Phase 1, Randomized, Comparative Pharmacokinetic Study of Bolus Intravenous Lidocaine 0.7 mg/kg, Lidocaine Patch 1.8%, and Lidocaine Patch 5% (Lidoderm®) in Healthy SubjectsStatus: Completed, Estimated PCD: 2014-07-24
Product
Lidocaine patchProduct
Lidocaine 5%Product
RG-RVProduct
LSD + KetanserinClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Levothyroxine Sodium Tablets (300 μg; Mylan) to Levothroid® Tablets (300 μg; Llyod) in Healthy Volunteers.Status: Completed, Estimated PCD: 2005-09-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Modafinil Tablets (200 mg; Mylan) and Provigil® Tablets (200 mg; Cephalon) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-10-01
Clinical trial
Effects of Oxytocin and Vasopressin on Moral Decision MakingStatus: Completed, Estimated PCD: 2022-12-12
Product
OxytocinProduct
TB001Clinical trial
Single-center, Open, Randomized, Single-dose, Two-cycle, Two-sequence, Crossover Bioequivalence Study to Evaluate the Effects of the Test and the Fed StatesStatus: Completed, Estimated PCD: 2021-03-17
Clinical trial
Common and Differentiated Representations Between Social Exclusion and Social SeparationStatus: Recruiting, Estimated PCD: 2023-09-20
Product
Budesonide/formoterolClinical trial
Myocardial Fibrosis and Changes of Myocardial Function Related to AgingStatus: Recruiting, Estimated PCD: 2024-06-20
Product
Blood samplingProduct
MescalineClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Oxybutynin Chloride ER Tablets (10 mg; Mylan) and Ditropan XL® Tablets (10 mg; ALZA) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-08-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Anagrelide Hydrochloride Capsules (1 mg; Mylan) to Agrylin® Capsules (1 mg; Shire US) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-01-01
Clinical trial
Non-intrusive Detection of Temporary Neurologic Impairment By OpioidsStatus: Completed, Estimated PCD: 2022-04-11
Product
OxycodoneClinical trial
A Randomized, Parallel-group, Placebo-controlled, Double-blind Phase 1/2a Study in Healthy HIV Uninfected Adults to Assess Safety/Tolerability and Immunogenicity of 2 Different Prime/Boost Regimens: Priming With Tetravalent Ad26.Mos4.HIV and Boosting With Tetravalent Ad26.Mos4.HIV and Either Clade C gp140 Plus Adjuvant OR a Combination of Mosaic and Clade C gp140 Plus AdjuvantStatus: Completed, Estimated PCD: 2023-11-22
Product
PyronaridineClinical trial
Single-Dose Fed In Vivo Bioequivalence Study of Azithromycin Tablets (600 mg; Mylan) to Zithromax® Tablets (600 mg; Pfizer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-05-01
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HydrochlorothiazideClinical trial
The PASTDUe Nutrition EcoSystem Pathway In Acute Care Abdominal Surgery and Trauma to Decrease Underfeeding and ComplicationsStatus: Recruiting, Estimated PCD: 2025-01-01
Product
Nutrition EcosystemClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Nitrofurantoin Monohydrate/Macrocrystals Capsules (100 mg; Mylan) and Macrobid® Capsules (100 mg; Procter & Gamble) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-11-01
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PhenytoinProduct
HU6Clinical trial
A Bridged Phase 1, Randomized, Double-blind, Placebo-controlled Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Multiple Doses of TBN in Healthy SubjectsStatus: Not yet recruiting, Estimated PCD: 2025-06-30
Clinical trial
A Single-center, Randomized, Double-Blind, Placebo-Controlled Phase 1 Single Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity Characteristics of 9MW3011 in Healthy VolunteersStatus: Active (not recruiting), Estimated PCD: 2024-04-01
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9MW3011Clinical trial
Pharmacokinetic Study to Evaluate the Whole Blood Pharmacokinetics of TP-03 Following Six Week Topical Ocular AdministrationStatus: Completed, Estimated PCD: 2021-09-03
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PRA023 IV Low DoseClinical trial
An Open-Label, Multiple Ascending Dose (MAD) Study to Evaluate the Safety, Tolerability and Pharmacokinetics of KBP-5074 in Healthy Subjects With a Separate Panel in Subjects With Mild to Moderate Renal ImpairmentStatus: Completed, Estimated PCD: 2016-05-26
Clinical trial
A PHASE 1, RANDOMIZED, OPEN-LABEL, 3-PERIOD, 3-TREATMENT, 6-SEQUENCE, CROSSOVER, SINGLE-DOSE STUDY IN HEALTHY ADULT PARTICIPANTS TO ESTIMATE THE BIOAVAILABILITY OF THE REGISTRATION TABLETS OF VEPDEGESTRANT (ARV-471, PF-07850327) RELATIVE TO THE PHASE 3 TABLETSStatus: Recruiting, Estimated PCD: 2024-06-16
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DWJ211Product
STSA-1201Clinical trial
A Randomized, Open-label, Two-Way Crossover Study to Evaluate Relative Bioavailability and Pharmacodynamics of Two Doses of HSK7653 in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-08-12
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RanitidineProduct
LY06006Clinical trial
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-68179280 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-03-07
Clinical trial
Phase 1 Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of ID120040002 in Healthy VolunteersStatus: Recruiting, Estimated PCD: 2023-07-31
Clinical trial
A Phase 1, Open-label, Randomized, 4-Way Crossover Pivotal Study to Assess the Bioequivalence of Four Different Oral Tablet Formulations of Lazertinib (JNJ-73841937) in Healthy Adult ParticipantsStatus: Completed, Estimated PCD: 2023-03-31
Clinical trial
A Phase I, Double Blind, Placebo Controlled, Single Ascending Dose Study of Intravenously Administered Ir-CPI to Evaluate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability in Healthy Male VolunteersStatus: Completed, Estimated PCD: 2020-07-18
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BI 655088Clinical trial
A Double Dummy, Double-blind Study to Assess the Safety, Tolerability, and Pharmacokinetics of PUR3100 in Health AdultsStatus: Completed, Estimated PCD: 2022-09-22
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AON-D21Product
HCP1803-3Clinical trial
A Randomized, Open, Single-dose, Crossover-design, Phase I Study to Evaluate Bioequivalence After Co-administration of ALO 12.5 mg and MET XR 500 mg or Administration of CT-L01 12.5/500 mg in Healthy VolunteersStatus: Completed, Estimated PCD: 2022-07-05
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Reference Product XProduct
T4Clinical trial
A Phase 1 Multiple-Dose Study to Investigate the Pharmacokinetics, Safety, and Tolerability of 2 Different Formulations of LY3502970 in Healthy ParticipantsStatus: Completed, Estimated PCD: 2022-09-01
Clinical trial
An Open-label, Randomized, Cross-over, Multiple Dose, Phase 1 Clinical Trial to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of DA-5207 Transdermal Delivery System in Healthy AdultsStatus: Completed, Estimated PCD: 2022-12-13
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XevinapantClinical trial
A PHASE 1, RANDOMIZED, DOUBLE-BLIND, THIRD-PARTY OPEN, PLACEBO CONTROLLED, STUDY TO EVALUATE THE PHARMACOKINETICS, SAFETY, AND TOLERABILITY FOLLOWING A SINGLE DOSE OF PF-06823859 IN HEALTHY CHINESE PARTICIPANTSStatus: Completed, Estimated PCD: 2023-03-21
Clinical trial
An Open Label Phase 1 Study in Healthy Adult Male Subjects to Investigate the Absorption, Metabolism, and Excretion of [14C]-TNP-2092 Following a Single Intravenous Dose AdministrationStatus: Completed, Estimated PCD: 2021-11-30
Clinical trial
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising Oral Doses of BI 690517 in Healthy Male SubjectsStatus: Completed, Estimated PCD: 2016-12-12
Clinical trial
A Phase 1, Open-Label Study in Healthy Adult Participants to Assess the Pharmacokinetics of JNJ-64281802 Administered as Different Multiple Dose RegimensStatus: Completed, Estimated PCD: 2022-12-11
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ErdafitinibClinical trial
An Open-label, Single-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of JNJ-77242113 Following Oral Administration in Healthy Chinese Adult ParticipantsStatus: Completed, Estimated PCD: 2023-04-07
Clinical trial
A Parallel-group, Phase 1, Open-label Study to Investigate the Pharmacokinetics of LY3437943 in Participants With Renal Impairment Compared With Healthy ParticipantsStatus: Completed, Estimated PCD: 2023-09-05
Clinical trial
A Single and Multiple Assending Doses Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamic Characteristics and Food Effect After Administration of HHT120 Capsule in Healthy SubjectsStatus: Withdrawn, Estimated PCD: 2023-02-15
Clinical trial
A Phase 1, Open-Label, 2-Period, Fixed Sequence Study to Estimate the Effect of Itraconazole on the Pharmacokinetics of PF-07817883 in Healthy AdultsStatus: Completed, Estimated PCD: 2023-07-10
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LebrikizumabProduct
BG00012Product
D-0120Clinical trial
A Phase I Clinical Study on the Safety, Tolerability and Pharmacokinetics of SI-F019 Recombinant Human Bivalent ACE2-Fc Fusion Protein Injection in a Single Dose in Healthy SubjectsStatus: Completed, Estimated PCD: 2021-09-20
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A Phase 1, Open-label, Single Dose Study to Investigate Pharmacokinetics, Safety and Tolerability of JNJ-63733657 in Healthy Chinese ParticipantsStatus: Completed, Estimated PCD: 2022-08-02
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A3Clinical trial
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Compare Fulvestrant Plus BPI-16350 or Plus Placebo in Patients With HR+, HER2- Locally Advanced, Recurrent or Metastatic Breast Cancer With Disease Progression Following Endocrine TherapyStatus: Active (not recruiting), Estimated PCD: 2023-12-31
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4F-PCCClinical trial
A Single Center, Double-Blinded, Phase 1a Randomized Study to Evaluate Safety and Pharmacokinetics of a New Manganese Based Magnetic Resonance Imaging (MRI) Contrast Agent, RVP-001, in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-07-22
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SHR8554；ItraconazoleProduct
XOLAIRProduct
DRV/COBI FDCClinical trial
A Single-dose, Open-label, Randomized, Crossover Pivotal Bioequivalence Study in Healthy Participants to Assess the Bioequivalence of Darunavir 600 mg in the Presence of Cobicistat 90 mg When Administered as a Fixed Dose Combination Tablet (Darunavir/Cobicistat) Compared to the Co-administration of the Separate Available Formulations (Darunavir 100 mg/mL Suspension at a Dose of 600 mg and Cobicistat 90 mg Tablet), Under Fed ConditionsStatus: Completed, Estimated PCD: 2022-09-28
Clinical trial
Pharmacokinetics, Safety, and Tolerability of BI 690517 in Subjects With Mild and Moderate Liver Impairment (Child-Pugh Classification A and B) as Compared to Healthy SubjectsStatus: Completed, Estimated PCD: 2023-04-13
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COBIProduct
SolirisClinical trial
A Phase I Bridging Study to Evaluate the PK, Safety and Tolerability of SR750 in Healthy SubjectsStatus: Completed, Estimated PCD: 2023-09-06
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SR750Clinical trial
A Phase 1 Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of XEN-101Status: Completed, Estimated PCD: 2023-05-30
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TR-01-XRSClinical trial
Comparative Pharmacokinetic Study of Aprepitant Injection in HumansStatus: Not yet recruiting, Estimated PCD: 2024-01-25
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SildenafilClinical trial
Pharmacokinetic Model Based on Population Physiology of Oral and Intranasal Formulations of Zolmitriptan in Healthy VolunteersStatus: Completed, Estimated PCD: 2023-09-06
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CitalopramClinical trial
A Randomized, Open-labelled Bronchoscopy Study to Assess the Effects of Inhaled Corticosteroids (ICS) on Adult Healthy VolunteersStatus: Active (not recruiting), Estimated PCD: 2026-10-31
Clinical trial
The Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of a Single Oral Dose BI 3000202 in Healthy Male Subjects (an Open-label, Randomized, Two-way Cross-over Study)Status: Recruiting, Estimated PCD: 2024-07-02
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BI 300202Clinical trial
Does Abnormal Insulin Action in the Brain Underlie Cognitive and Metabolic Dysfunction in SchizophreniaStatus: Recruiting, Estimated PCD: 2025-04-01
Clinical trial
Single-Dose Fasting Bioequivalence Study of Topiramate Sprinkle Capsules (25 mg; Mylan) and Topamax® Sprinkle Capsules (25 mg; Ortho-McNeil Neurologics) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-12-01
Clinical trial
Novel Treatment for Brain Insulin Resistance and HypoperfusionStatus: Recruiting, Estimated PCD: 2026-06-01
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Human insulinClinical trial
In Vivo Study of Neuroinflammation in Tobaccosmoking: a Clinical Positron EmissionTomography (PET) Study of 18 kDa TranslocatorProtein (TSPO) Using [18F]PBR111 (Part A)Status: Not yet recruiting, Estimated PCD: 2025-05-01
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Tramadol Administered Orally to Healthy Subjects for the Improvement of Its Detection in Biological Matrices in the Context of Anti-Doping ControlStatus: Completed, Estimated PCD: 2023-10-11
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An Assessment of the Acute Effects of Herbal Dietary Supplements on Aerobic Performance in Recreational AthletesStatus: , Estimated PCD: 2024-01-19
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Herbal SupplementClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Balsalazide Disodium Capsules (750 mg; Mylan) and Colazal® Capsules (750 mg; Salix) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-05-01
Clinical trial
Study of Mylan Pharmaceuticals Inc. and Novartis Pharmaceuticals Corporation (Parlodel®) 2.5 mg Bromocriptine Mesylate Tablets Following a 10 mg Dose in Healthy Adult Volunteers Under Fed ConditionsStatus: Completed, Estimated PCD: 2007-07-01
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Intranasal naloxoneProduct
Placebo gumProduct
MethamphetamineClinical trial
A Randomized, Open-label, Crossover Phase 1 Clinical Trial to Evaluate the Safety, Pharmacokinetic Characteristics and the Effect of Food After Administration of JLP-2004 in Healthy Adult VolunteersStatus: Recruiting, Estimated PCD: 2024-06-30
Clinical trial
Beta1-Selective Blockade for Prevention of Postmenopausal Bone Loss: A Phase 2, Multi-Center, Double-Blinded, Randomized Placebo-Controlled TrialStatus: Active (not recruiting), Estimated PCD: 2025-12-31
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A Single Center, Open Label, Randomized, Single-dose, Two-period, Two-way Cross-over Study to Compare the Rate and Extent of Absorption of DelanzoᵀᴹDR 60mg (Dexlansoprazole) Capsule With Dexilant® 60mg (Dexlansoprazole) Capsule in Healthy Pakistani Subjects.Status: Completed, Estimated PCD: 2022-10-25
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Glipizide and Metformin HClClinical trial
Single-center, Open, Randomized, Single-dose, Crossover Bioequivalence Study Evaluating the Use of the Subject Formulation, Empagliflozin And Linagliptin Tablets, Versus the Reference Formulation, Empagliflozin And Linagliptin Tablets (Glyxambi®), in Healthy Adult SubjectsStatus: Completed, Estimated PCD: 2022-11-23
Clinical trial
MTX-463-I101: A Phase 1 Randomized, Double-Blind, Dose-Escalating Study to Assess the Safety, Tolerability, and Pharmacokinetics of MTX-463 in Healthy AdultsStatus: Recruiting, Estimated PCD: 2024-11-16
Clinical trial
A Phase 1, Single-blind, Randomized, Parallel-group Study in Healthy Participants to Investigate the Single-dose Pharmacokinetics, Safety and Tolerability of Rilpivirine After Subcutaneous Administration of a Rilpivirine Extended-Release Suspension Alone, and of Rilpivirine and Cabotegravir After Co-administration With Cabotegravir Extended-Release SuspensionStatus: Active (not recruiting), Estimated PCD: 2024-05-23
Clinical trial
Single-Dose Fasting Bioequivalence Study of Verapamil HCl Extended-Release Capsules (300 mg;Mylan) and Verelan® PM Extended-Release Capsules (300 mg; Schwarz) Sprinkled on Applesauce in Healthy VolunteersStatus: Completed, Estimated PCD: 2006-01-01
Clinical trial
Single-Dose Food In Vivo Bioequivalence Study of Oxybutynin Chloride Extended-release Tablets (5 mg; Mylan) and Ditropan XL® Tablets (5 mg; ALZA) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Quinapril Hydrochloride Tablets (40 mg; Mylan) and Accupril® Tablets (40 mg; Parke-Davis) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Product
Amlodipine and BenazeprilProduct
LotrelClinical trial
Single-Dose Food In Vivo Bioequivalence Study of Sertraline Hydrochloride Tablets (100 mg; Mylan) and Zoloft® Tablets (100 mg; Pfizer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2002-12-01
Product
N-acetyl cysteineClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Ciprofloxacin Extended-Release Tablets (500 mg; Mylan) and Cipro® XR Tablets (500 mg; Bayer) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-11-01
Clinical trial
A Phase 1, Randomized, Double-Blind, Single-Dose, Dose Escalation Study to Determine the Safety, Tolerability, and Pharmacokinetics of CD101 Injection in Healthy SubjectsStatus: Completed, Estimated PCD: 2015-10-01
Clinical trial
Functional Neuroimaging Effects of the N-methyl-D-aspartate Receptor (NMDAR) Partial Agonist, GLYX-13, on Learning and Memory in Healthy IndividualsStatus: Terminated, Estimated PCD: 2016-01-01
Product
GLYX-13Product
EntolimodProduct
Influenza vaccineProduct
TGIRProduct
InsulinProduct
Oral Lollipop with OxytocinProduct
Oral LollipopClinical trial
Phase I Pharmacokinetic Pilot Study to Investigate the Bioavailability and Tolerability of Three Different Oral Formulations of Sodium ThiosulfateStatus: Withdrawn, Estimated PCD: 2019-05-01
Clinical trial
A Partially Randomised, Single-blind, Placebo-controlled Trial to Investigate Safety, Tolerability, and Pharmacokinetics of Single Rising Doses of BI 3731579 Administered as Tablet to Healthy Male SubjectsStatus: Not yet recruiting, Estimated PCD: 2024-10-31
Product
BI 3731579Clinical trial
Role of the Serotonin 5-HT2A Receptor in Mescaline-induced Altered States of ConsciousnessStatus: Completed, Estimated PCD: 2023-03-27
Clinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Metformin Hydrochloride ER Tablets (750 mg; Mylan) and Glucophage® XR Tablets (750 mg; Bristol-Myers Squibb) in Healthy VolunteersStatus: Completed, Estimated PCD: 2003-12-01
Product
PurinetholClinical trial
Single-Dose Fasting In Vivo Bioequivalence Study of Metformin Hydrochloride ER Tablets (500 mg; Mylan) and Glucophage® XR Tablets (500 mg; Bristol-Myers Squibb) in Healthy VolunteersStatus: Completed, Estimated PCD: 2004-03-01
Clinical trial
Single-Dose Fasting Bioequivalence Study of Propranolol Hydrochloride Extended-Release Capsules (160 mg; Mylan) and Inderal® LA Capsules (160 mg; Wyeth) in Healthy VolunteersStatus: Completed, Estimated PCD: 2005-09-01
Product
Ammonul