R-CHOP

Aliases
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione, 1, 2-Dehydrocortisone, 2-Dehydrocortisone, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8, 9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, hydrochloride, (8S-cis)- (9CI), Adasone (152 other aliases)

302 clinical trials

47 products

15 abstracts

478 indications

10 targets

Indication
Untreated
Indication
Prostate Cancer
Indication
Acute
Indication
Childhood
Indication
Leukemia
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Lymphoblastic
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T cell
Indication
Ovarian Cancer
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Cervical Cancer
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Vulvar Cancer
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Crohn's disease
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hepatoblastoma
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cancer
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Hepatocellular
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Breast Cancer
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Breast cancer
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Bladder Cancer
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Pediatric
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Low Back Pain
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Osteoarthritis
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Medulloblastoma
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Healthy
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Myocarditis
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cervical
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Uveitis
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posterior
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Intermediate
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Panuveitis
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Wilms tumor
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Facial Palsy
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Bell's Palsy
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BCR-ABL1-like
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Chronic GVHD
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Leiomyosarcoma
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Ewing Sarcoma
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Wrist Fractures
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Wilms Tumor
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Lupus Nephritis
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Cancer
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Asthma
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Duchenne
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Retinoblastoma
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Osteoporosis
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MRD
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Cardiomyopathy
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Secondary
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lymphoma
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BRCA2
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CHEK2 mutation
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Fanconi anemia
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RAD51B
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Liver Cancer
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Anaemia
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Unclassifiable
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Myelofibrosis
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Glaucoma
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Neurotoxicity
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Solid Tumor
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urethral cancer
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Adult
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Blood Cancer
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Exacerbation
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Pneumonitis
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HIV Infection
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Cogan Syndrome
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COVID-19
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Remodeling
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Left Ventricle
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Vascular
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Vasculitis
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B-cell Neoplasm
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NOS
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Ethmoidal
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Sphenoidal
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Neuroblastoma
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Bone Sarcoma
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Anosmia
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melanoma
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Prostate cancer
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B-cell
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lung cancer
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Lung Metastases
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Sarcoma
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Skin Cancer
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Drug Toxicity
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pericarditis
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Corticosteroid
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Mortality
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Lung Diseases
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Obstructive
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Liver
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Cancer of
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B-cell Lymphoma
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Resectable
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Glucocorticoids
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Only
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Facial Swelling
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Malocclusion
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Dental Caries
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Impacted
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Dental Avulsion
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Soft Tissue
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Liposarcoma
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Angiosarcoma
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fibrosarcoma
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tendinopathy
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Arthritis
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Rheumatoid
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Glioma
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Glioblastoma
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Mixed Glioma
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Astrocytoma
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Sarcoidosis
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Pulmonary
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Frozen Shoulder
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ALK-Negative
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ALK-positive
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t(9;22)
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Trigger Finger
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HHV-8
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HIV
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Fanconi Anemia
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B-cell lymphoma
Target
PSA
Target
ECOG
Target
CD20
Target
Tubulin
Target
DNA
Indication
Safety Issues
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kidney
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Pancreas
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Gout
Abstract
Tucidinostat plus R-CHOP in previously untreated diffuse large B-cell lymphoma with double expression of MYC and BCL2: An interim analysis from the phase III DEB study.
Org: Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Peking University Cancer Hospital and Institute (Beijing Cancer Hospital),
Abstract
HDAC I/IIb selective inhibitor purinostat mesylate in relapsed and refractory diffuse large B-cell lymphoma: A single agent phase IIa trial.
Org: Department of Hematology,The First Affiliated Hospital of Chongqing Medical University, Department of Hematology and Oncology, Chongqing University Cancer Hospital, Department of Hematology Oncology, YunNan Provincial Cancer Hospital, Department of Lymphoma Medicine, Hubei Cancer Hospital, Department of Lymphoma and Hematology, Hunan Cancer Hospital,
Clinical trial
Top-down Infliximab Study in Kids With Crohn's Disease
Status: Completed, Estimated PCD: 2019-12-01
Abstract
Rituximab, chidamide, and zanubrutinib (ZCR) ± CHOP as a regimen for treatment naive (TN) double-expressor DLBCL (DE-DLBCL).
Org: Affiliated Dongguan People’s Hospital, Dongguan People’s Hospital,
Abstract
Phase 3 trial evaluating the efficacy and safety of odronextamab versus investigator’s choice in previously untreated follicular lymphoma (OLYMPIA-1).
Org: Hematology Oncology of Indiana/American Oncology Network, Azienda Unità Sanitaria Locale-IRCCS, Gazi Universitesi Tip Fakültesi, ProHealth Care,
Abstract
Randomized phase II/III study of R-CHOP +/- venetoclax in previously untreated MYC/BCL2 double expressor diffuse large B cell lymphoma (DLBCL): Alliance A051701.
Org: Massachusetts General Hospital, Alliance Statistics and Data Management Center, Mayo Clinic Rochester, Rochester, MN, Mayo Clinic, National Cancer Institute, Vilnius, Lithuania,
Abstract
Genomic profiling in a subgroup analysis of patients (pts) with diffuse large B-cell lymphoma (DLBCL) and extranodal (EN) sites of involvement in the phase 3 Pola-R-CHP versus R-CHOP (POLARIX) study.
Org: Centre Henri-Becquerel and University of Rouen, University Hospital Münster, M.D. Anderson Cancer Center, Charles University General Hospital, University of Montpellier,
Abstract
Real-world cost of disease progression (PD) after frontline (1L) R-CHOP in diffuse large B-cell lymphoma (DLBCL): An analysis of a large US claims database.
Org: Rocky Mountain Cancer Centers, The US Oncology Network, Aurora, CO, Genentech, South San Francisco, CA,
Clinical trial
Paediatric Hepatic International Tumour Trial
Status: Active (not recruiting), Estimated PCD: 2026-08-01
Clinical trial
Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) I
Status: Active (not recruiting), Estimated PCD: 2022-05-10
Clinical trial
A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma
Status: Active (not recruiting), Estimated PCD: 2024-09-01
Clinical trial
Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17
Status: Recruiting, Estimated PCD: 2027-01-01
Clinical trial
ALL Adult Consortium Trial: Adult ALL Trial
Status: Active (not recruiting), Estimated PCD: 2023-12-01
Clinical trial
A Phase 1b/2 Trial of Lurbinectedin Plus Doxorubicin in Leiomyosarcoma
Status: Recruiting, Estimated PCD: 2024-07-01
Clinical trial
Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT)
Status: Not yet recruiting, Estimated PCD: 2031-02-13
Clinical trial
Safety and Efficacy of Prednisolone in Adrenal Insufficiency Disease (PRED-AID Study)
Status: Active (not recruiting), Estimated PCD: 2025-02-01
Clinical trial
Adjuvant Treatment in Extensive Unilateral Retinoblastoma Primary Enucleated
Status: Recruiting, Estimated PCD: 2030-03-01
Clinical trial
Identifying Individuals at Risk of Glucocorticoid-Induced Impairment of Bone Disease
Status: Not yet recruiting, Estimated PCD: 2025-12-01
Clinical trial
Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy
Status: Recruiting, Estimated PCD: 2024-10-01
Clinical trial
Pharmacogenetic Study in Hepatocellular Carcinoma Patients Underwent TACE
Status: Completed, Estimated PCD: 2023-03-31
Clinical trial
Treatment of Children With Newly-Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD)
Status: Active (not recruiting), Estimated PCD: 2015-10-06
Clinical trial
Optimizing Immunosuppression for Steroid-Refractory Anti-PD-1/PD-L1 Pneumonitis
Status: Terminated, Estimated PCD: 2023-12-21
Clinical trial
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma
Status: Active (not recruiting), Estimated PCD: 2026-09-30
Clinical trial
Nivolumab and AVD in Early-stage Unfavorable Classical Hodgkin Lymphoma
Status: Active (not recruiting), Estimated PCD: 2023-12-01
Clinical trial
Prospective Tissue Collection in Breast Cancer Patients Receiving Preoperative Systemic Therapy
Status: Active (not recruiting), Estimated PCD: 2025-12-01
Clinical trial
A Phase 3 Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer
Status: Active (not recruiting), Estimated PCD: 2024-07-01
Clinical trial
Steroid Loaded Intranasal Films as a Local Treatment of Anosmia
Status: Completed, Estimated PCD: 2023-03-18
Clinical trial
Immune Checkpoint Blockade for Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers
Status: Active (not recruiting), Estimated PCD: 2022-10-11
Clinical trial
High Dose Oral Steroids in Sudden Sensorineural Hearing Loss
Status: Completed, Estimated PCD: 2022-08-01
Clinical trial
Phase II Study of Infliximab for the Treatment of Immune Checkpoint Inhibitor Colitis
Status: Recruiting, Estimated PCD: 2030-06-30
Clinical trial
Methotrexate and Prednisolone Study in Erythema Nodosum Leprosum (MaPS in ENL
Status: Recruiting, Estimated PCD: 2023-12-01
Clinical trial
Intra-articular Platelet Rich Plasma vs Corticosteroid in Treatment of Knee Osteoarthritis
Status: Not yet recruiting, Estimated PCD: 2023-10-01
Clinical trial
Gene Transfer for Patients With Fanconi Anemia Complementation Group A (FANCA)
Status: Terminated, Estimated PCD: 2024-02-15
Abstract
Edema and serositis as an adverse event in patients with cancer receiving immune checkpoint blockade: Systematic review to evaluate this immune-related adverse event and associated treatment strategies.
Org: Mount Sinai Beth Israel, Center for Thoracic Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai/Tisch Cancer Institute, Department of Medicine, Icahn School of Medicine at Mount Sinai,
Abstract
Phase II trial of split-dose R-CHOP for older patients with diffuse large B-cell lymphoma (DLBCL).
Org: Medical College of Wisconsin, Froedtert & Medical College of Wisconsin, Division of Biostatistics, Department of Data Science, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, University of Wisconsin Madison School of Medicine and Public Health, Division of Hematology & Oncology,
Abstract
Circulating tumor DNA (ctDNA) status and clinical outcomes in patients (pts) with previously untreated diffuse large B-cell lymphoma (DLBCL) in the POLARIX study.
Org: City of Hope National Medical Center, Genentech, BC Cancer Centre for Lymphoid Cancer, Centre Henri-Becquerel and University of Rouen, University Hospital Münster,
Abstract
ZUMA-23: A global, phase 3, randomized controlled study of axicabtagene ciloleucel versus standard of care as first-line therapy in patients with high-risk large B-cell lymphoma.
Org: Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, Dana-Farber Cancer Institute, Boston, MA, USA, Moffitt Cancer Center and Research Institute, Tampa, FL, Hematology Department, Institut Català d'Oncologia-Hospitalet, Barcelona, Spain, University of Lille, Centre Hospitalier Universitaire, Lille, France,
Abstract
Feasibility of CAR-T in very old patients with relapsed/refractory diffuse large B-cell lymphoma.
Org: H. Lee Moffitt Cancer Center and Research Institute,
Abstract
Doxorubicin to enhance the abscopal effect depending on tumor cell mitochondrial DNA and cGAS/STING.
Org: Harbin Medical University Cancer Hospital, West China Hospital, University of Freiburg, Department of Radiation Oncology,
Product
R-CHOP
Product
AVA6000
Product
Prednisone
Clinical trial
Efficacy and Safety of Hydroxychloroquine in the Treatment of Sudden Sensorineural Hearing Loss
Status: Not yet recruiting, Estimated PCD: 2026-05-31